The potential of omics approaches to elucidate mechanisms of biodiesel-induced pulmonary toxicity

Authors: Liza Selley, David H. Phillips, Ian Mudway

Source: Particle and Fibre Toxicology, Vol 16, Iss 1, Pp 1-16 (2019)

Subject Terms: Biodiesel, Pulmonary toxicity, Transcriptomics, Metabolomics, Hypothesis generation, Mechanism, Toxicology. Poisons, RA1190-1270, Industrial hygiene. Industrial welfare, HD7260-7780.8

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12989-018-0284-y; https://doaj.org/toc/1743-8977

Access URL: https://doaj.org/article/2383c9da3d9a4a15a80036c337f31b96

EXPOsOMICS: final policy workshop and stakeholder consultation

Authors: Michelle C. Turner, Paolo Vineis, Eduardo Seleiro, Michaela Dijmarescu, David Balshaw, Roberto Bertollini, Marc Chadeau-Hyam, Timothy Gant, John Gulliver, Ayoung Jeong, Soterios Kyrtopoulos, Marco Martuzzi, Gary W. Miller, Timothy Nawrot, Mark Nieuwenhuijsen, David H. Phillips, Nicole Probst-Hensch, Jonathan Samet, Roel Vermeulen, Jelle Vlaanderen, Martine Vrijheid, Christopher Wild, Manolis Kogevinas, on behalf of the EXPOsOMICS Consortium

Source: BMC Public Health, Vol 18, Iss 1, Pp 1-11 (2018)

Subject Terms: Exposome, Workshop report, External exposome, Internal exposome, Air pollution, Water contamination, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12889-018-5160-z; https://doaj.org/toc/1471-2458

Access URL: https://doaj.org/article/c710a420e6aa42229449fce0036c7503

Visualisation tools for dependent peptide searches to support the exploration of in vitro protein modifications.

Authors: George W Preston, Liping Yang, David H Phillips, Claudia S Maier

Source: PLoS ONE, Vol 15, Iss 7, p e0235263 (2020)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0235263&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/0ca3bd08bfd54c158438e28c66446bcb

From the exposome to mechanistic understanding of chemical-induced adverse effects

Authors: Beate I. Escher, Jörg Hackermüller, Tobias Polte, Stefan Scholz, Achim Aigner, Rolf Altenburger, Alexander Böhme, Stephanie K. Bopp, Werner Brack, Wibke Busch, Marc Chadeau-Hyam, Adrian Covaci, Adolf Eisenträger, James J. Galligan, Natalia Garcia-Reyero, Thomas Hartung, Michaela Hein, Gunda Herberth, Annika Jahnke, Jos Kleinjans, Nils Klüver, Martin Krauss, Marja Lamoree, Irina Lehmann, Till Luckenbach, Gary W. Miller, Andrea Müller, David H. Phillips, Thorsten Reemtsma, Ulrike Rolle-Kampczyk, Gerrit Schüürmann, Benno Schwikowski, Yu-Mei Tan, Saskia Trump, Susanne Walter-Rohde, John F. Wambaugh

Source: Environment International, Vol 99, Iss , Pp 97-106 (2017)

Subject Terms: Environmental sciences, GE1-350

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0160412016309187; https://doaj.org/toc/0160-4120

Access URL: https://doaj.org/article/1e10d437cf274ea0a58837bf35c10e71

Protein Adductomics: Analytical Developments and Applications in Human Biomonitoring

Authors: George W. Preston, David H. Phillips

Source: Toxics, Vol 7, Iss 2, p 29 (2019)

Subject Terms: haemoglobin, albumin, mass spectrometry, biomarkers, protein adducts, Chemical technology, TP1-1185

File Description: electronic resource

Relation: https://www.mdpi.com/2305-6304/7/2/29; https://doaj.org/toc/2305-6304

Access URL: https://doaj.org/article/0a8f41ba48b946129d299198da718c0c

Molecular and Metabolic Consequences Following E6 Transfection in an Isogenic Ovarian Cell Line (A2780) Pair

Authors: Yuen-Li Chung, Eszter Nagy, Dominik Zietkowski, Geoffrey S. Payne, David H. Phillips, Nandita M. deSouza

Source: Cellular Physiology and Biochemistry, Vol 32, Iss 5, Pp 1460-1472 (2013)

Subject Terms: Glycerophosphocholine, Glutamine metabolism, Glucose metabolism, cPLA2, Metabolomics, HPV E6, Proton magnetic resonance spectroscopy, Physiology, QP1-981, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.karger.com/Article/FullText/356583; https://doaj.org/toc/1015-8987; https://doaj.org/toc/1421-9778

Access URL: https://doaj.org/article/7ffc3df2d8174d80b7c7a9004042324a

Exposure to polycyclic aromatic hydrocarbons among never smokers in Golestan Province, Iran, an area of high incidence of esophageal cancer – a cross-sectional study with repeated measurement of urinary 1-OHPG in two seasons

Authors: Farhad eIslami, Paolo eBoffetta, Frederik J van Schooten, Paul eStrickland, David H Phillips, Akram ePourshams, Akbar eFazel-Tabar Malekshah, Roger eGodschalk, Elham eJafari, Arash eEtemadi, Salahadin eAbubaker, Farin eKamangar, Kurt eStraif, Henrik eMøller, Joachim eSchüz, Reza eMalekzadeh

Source: Frontiers in Oncology, Vol 2 (2012)

Subject Terms: esophageal cancer, polymorphism, 1-hydroxypyrene glucuronide, frying, polycyclic aromatic hydrocarbon, red meat, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00014/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/9d82e27238554d42ada1508acdff6390

STrengthening the Reporting of OBservational studies in Epidemiology--Molecular Epidemiology (STROBE-ME): an extension of the STROBE Statement.

Authors: Valentina Gallo, Matthias Egger, Valerie McCormack, Peter B Farmer, John P A Ioannidis, Micheline Kirsch-Volders, Giuseppe Matullo, David H Phillips, Bernadette Schoket, Ulf Stromberg, Roel Vermeulen, Christopher Wild, Miquel Porta, Paolo Vineis, STROBE Statement

Source: PLoS Medicine, Vol 8, Iss 10, p e1001117 (2011)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22039356/?tool=EBI; https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

Access URL: https://doaj.org/article/90ea98b7304f471c879937baaae572c0

Role of P450 1A1 and P450 1A2 in Bioactivation versus Detoxication of the Renal Carcinogen Aristolochic Acid I: Studies in Cyp1a1(−/−), Cyp1a2(−/−), and...

Authors: Volker M. Arlt, Kateřina Levová, František Bárta, Zhanquan Shi, James D. Evans, Eva Frei, Heinz H. Schmeiser, Daniel W. Nebert, David H. Phillips, Marie Stiborová

Source: Chemical Research in Toxicology; Oct2011, Vol. 24 Issue 10, p1710-1719, 10p

Mechanisms of the Different DNA Adduct Forming Potentials of the Urban Air Pollutants 2-Nitrobenzanthrone and Carcinogenic 3-Nitrobenzanthrone.

Authors: Marie Stiborová, Václav Martínek, Martina Svobodová, Jana Šístková, Zdeněk Dvořák, Jitka Ulrichová, Vilím Šimánek, Eva Frei, Heinz H. Schmeiser, David H. Phillips, Volker M. Arlt

Source: Chemical Research in Toxicology; Jul2010, Vol. 23 Issue 7, p1192-1201, 10p

Interlaboratory and Interplatform Comparison of Microarray Gene Expression Analysis of HepG2 Cells Exposed to Benzo(a)pyrene.

Authors: Sarah L. Hockley, Karen Mathijs, Yvonne C.M. Staal, Daniel Brewer, Ian Giddings, Joost H.M. van Delft, David H. Phillips

Source: OMICS: A Journal of Integrative Biology; Apr2009, Vol. 13 Issue 2, p115-125, 11p

Biotransformation of Benzo[a]pyrene in Ahr Knockout Mice Is Dependent on Time and Route of Exposure.

Authors: Carlos Sagredo, Steen Mollerup, Kathleen J. Cole, David H. Phillips, Heidi Uppstad, Steinar Øvrebø

Source: Chemical Research in Toxicology; Mar2009, Vol. 22 Issue 3, p584-591, 8p

AHR- and DNA-Damage-Mediated Gene Expression Responses Induced by Benzo(a)pyrene in Human Cell Lines.

Authors: Sarah L. Hockley, Volker M. Arlt, Daniel Brewer, Robert te Poele, Paul Workman, Ian Giddings, David H. Phillips

Source: Chemical Research in Toxicology; Oct2007, Vol. 20 Issue 12, p1797-1810, 14p

Growth kinetics in MCF-7 cells modulate benzo[a]pyrene-induced CYP1A1 up-regulation.

Authors: Haiyan Jiao, Sarah L. Allinson, Michael J. Walsh, Rebecca Hewitt, Kathy J. Cole, David H. Phillips, Francis L. Martin

Source: Mutagenesis; Mar2007, Vol. 22 Issue 2, p111-116, 6p

Subject Terms: CARCINOGENS, BENZOPYRENE, CYTOCHROMES, CANCER cells

Early proximal tubule injury in experimental aristolochic acid nephropathy: functional and histological studies.

Authors: Catherine Lebeau, Frédéric D. Debelle, Volker M. Arlt, Agnieszka Pozdzik, Eric G. De Prez, David H. Phillips, Monique M. Deschodt-Lanckman, Jean-Louis Vanherweghem, Joëlle L. Nortier

Source: Nephrology Dialysis Transplantation; Nov2005, Vol. 20 Issue 11, p2321-2332, 12p

Hepatic DNA adduct dosimetry in rats fed tamoxifen: a comparison of methods.

Authors: Laura J. Schild, David H. Phillips, Martin R. Osborne, Alan Hewer, Frederick A. Beland, Mona I. Churchwell, Karen Brown, Margaret Gaskell, Elizabeth Wright, Miriam C. Poirier

Source: Mutagenesis; Mar2005, Vol. 20 Issue 2, p115-124, 10p

Subject Terms: MURIDAE, ANTINEOPLASTIC agents, TAMOXIFEN, NUCLEIC acids

Modulation of N-methyl-N-nitrosourea-induced crypt restricted metallothionein immunopositivity in mouse colon by a non-genotoxic diet-related chemical.

Authors: Eilish T. Donnelly, Helen Bardwell, Geraldine Anne Thomas, E. Dillwyn Williams, Margaret Hoper, Paul Crowe, Wilson G. McCluggage, Michael Stevenson, David H. Phillips, Alan Hewer, Martin R. Osborne, Frederick C. Campbell

Source: Carcinogenesis; Vol. 25 Issue 5, p847-855, 9p

DNA adducts and mutagenic specificity of the ubiquitous environmental pollutant 3-nitrobenzanthrone in Muta Mouse.

Authors: Volker M. Arlt, Li Zhan, Heinz H. Schmeiser, Masamitsu Honma, Makoto Hayashi, David H. Phillips, Takayoshi Suzuki

Source: Environmental & Molecular Mutagenesis; 2004, Vol. 43 Issue 3, p186-195, 10p

Activation of 3-nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cells.

Authors: Volker M. Arlt, Hansruedi Glatt, Eva Muckel, Ulrike Pabel, Bernd L. Sorg, Albrecht Seidel, Heinz Frank, Heinz H. Schmeiser, David H. Phillips

Source: International Journal of Cancer; 7/10/2003, Vol. 105 Issue 5, p583, 10p

Subject Terms: CARCINOGENS, DIESEL motor exhaust gas, AIR pollution

This result is not displayed to guests.
Login for full access.