Gucy1α1 specifically marks kidney, heart, lung and liver fibroblasts

Authors: Valeria Rudman-Melnick, Davy Vanhoutte, Kaitlynn Stowers, Michelle Sargent, Mike Adam, Qing Ma, Anne Karina T. Perl, Alexander G. Miethke, Ashley Burg, Tiffany Shi, David A. Hildeman, E. Steve S. Woodle, J. Matthew Kofron, Prasad Devarajan

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)

Subject Terms: Kidney fibrosis, CKD, Multiorgan fibroblast marker, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/9640b9d662d8426cb449a1fbe232065c

Prior viral infection primes cross-reactive CD8+ T cells that respond to mouse heart allografts

Authors: M. Eyad Khorki, Tiffany Shi, Eileen E. Cianciolo, Ashley R. Burg, P. Chukwunalu Chukwuma, Jennifer L. Picarsic, Mary K. Morrice, E. Steve Woodle, Jonathan S. Maltzman, Autumn Ferguson, Jonathan D. Katz, Brian M. Baker, David A. Hildeman

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: transplant, cross-reactivity, TCR (T cell receptor), LCMV (lymphocytic choriomeningitis virus), transplantation, CD8+ T cell response, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1287546/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/555d23a18c6843c39ebce9e0a10efea5

Naturally-aged microglia exhibit phagocytic dysfunction accompanied by gene expression changes reflective of underlying neurologic disease

Authors: Alyssa L. Thomas, Maria A. Lehn, Edith M. Janssen, David A. Hildeman, Claire A. Chougnet

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/155b2661eb834da5aff628b3216a5b65

Antigen-specific decidual CD8+ T cells include distinct effector memory and tissue-resident memory cells

Authors: Shweta Mahajan, Aria Alexander, Zachary Koenig, Nicholas Saba, Nina Prasanphanich, David A. Hildeman, Claire A. Chougnet, Emily DeFranco, Sandra Andorf, Tamara Tilburgs

Source: JCI Insight, Vol 8, Iss 17 (2023)

Subject Terms: Immunology, Reproductive biology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/781060653b01409aa72fd46062791775

Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality

Authors: Tiffany Shi, Ashley R. Burg, J. Timothy Caldwell, Krishna M. Roskin, Cyd M. Castro-Rojas, P. Chukwunalu Chukwuma, George I. Gray, Sara G. Foote, Jesus A. Alonso, Carla M. Cuda, David A. Allman, James S. Rush, Catherine H. Regnier, Grazyna Wieczorek, Rita R. Alloway, Adele R. Shields, Brian M. Baker, E. Steve Woodle, David A. Hildeman

Source: The Journal of Clinical Investigation, Vol 133, Iss 14 (2023)

Subject Terms: Immunology, Transplantation, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/42e02f11da09405283e3b6ddcd572117

Aging mitigates the severity of obesity-associated metabolic sequelae in a gender independent manner

Authors: Maria E. Moreno-Fernandez, Vishakha Sharma, Traci E. Stankiewicz, Jarren R. Oates, Jessica R. Doll, Michelle S. M. A. Damen, Maha A. T. A. Almanan, Claire A. Chougnet, David A. Hildeman, Senad Divanovic

Source: Nutrition & Diabetes, Vol 11, Iss 1, Pp 1-13 (2021)

Subject Terms: Nutritional diseases. Deficiency diseases, RC620-627

File Description: electronic resource

Relation: https://doaj.org/toc/2044-4052

Access URL: https://doaj.org/article/7d0c748d3a344ab1a14d117f2eb1e4a9

Implications of Inflammatory States on Dysfunctional Immune Responses in Aging and Obesity

Authors: Alyssa L. Thomas, Pablo C. Alarcon, Senad Divanovic, Claire A. Chougnet, David A. Hildeman, Maria E. Moreno-Fernandez

Source: Frontiers in Aging, Vol 2 (2021)

Subject Terms: aging, obesity, inflammaging, anti-inflammation, immune system, immunosenecence, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fragi.2021.732414/full; https://doaj.org/toc/2673-6217

Access URL: https://doaj.org/article/071eff6706d84f6c9f411082e6cb5b5d

The Variable Genomic NK Cell Receptor Locus Is a Key Determinant of CD4+ T Cell Responses During Viral Infection

Authors: Jana Raynor, Adora Lin, Sarah A. Hummel, Kristin Lampe, Michael Jordan, Kasper Hoebe, David A. Hildeman

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: NK cells, NK DC cross talk, CD4 T cells, viral infection, innate, adaptive immune response, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.00197/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/a73f170725f04db8a4eb0e4e13944ccd

Increased Yield of Plasmid DNA During Removal of CsCl by Ethanol Precipitation

Authors: David A. Hildeman, Daniel Muller

Source: BioTechniques, Vol 22, Iss 5, Pp 878-879 (1997)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/0736-6205; https://doaj.org/toc/1940-9818

Access URL: https://doaj.org/article/2e52a516eea64a16b6111afae26a9e3f

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1009 In-depth analysis of myeloid cell subsets in lupus nephritis kidneys provides insights into disease mechanisms: lessons from the accelerating medicines partnership (AMP) in RA/SLE consortium

Authors: Richard Furie, Joel M Guthridge, Judith A James, Maria Dall’Era, Michelle A Petri, Chaim Putterman, Jill P Buyon, Diane L Kamen, Betty Diamond, David Wofsy, Soumya Raychaudhuri, Thomas Tuschl, Jennifer Grossman, Peter M Izmirly, Qian Xiao, Nir Hacohen, Kenneth C Kalunian, Michael B Brenner, Mariko Ishimori, H Michael Belmont, Robert Clancy, ANNE DAVIDSON, Matthias Kretzler, Michael Weisman, Celine C Berthier, Andrea Fava, Jennifer L Barnas, Jennifer H Anolik, Paul J Hoover, Deepak A Rao, Arnon Arazi, William Apruzzese, Fernanda Payan-Schober, Joseph Mears, Saori Sakaue, James Lederer, Michael Peters, Tony Jones, Thomas M Eisenhaure, Siddarth Gurajala, Derek Fine, David A Hildeman, Steve Woodle, Maureen A McMahon, Jeffery Hodgin

Source: Lupus Science and Medicine, Vol 11, Iss Suppl 2 (2024)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2053-8790

Access URL: https://doaj.org/article/65b7bcfbd80b4d188bbcb8ba5050d6cc

1107 Immune cell heterogeneity in lupus nephritis kidneys and its relation to histopathological features: lessons from the accelerating medicines partnership (AMP) in SLE Consortium

Authors: Richard Furie, Joel M Guthridge, Judith A James, Maria Dall’Era, Michelle A Petri, Chaim Putterman, Jill P Buyon, Diane L Kamen, Betty Diamond, David Wofsy, Soumya Raychaudhuri, Thomas Tuschl, Jennifer Grossman, Peter M Izmirly, Qian Xiao, Nir Hacohen, Kenneth C Kalunian, Michael B Brenner, Mariko Ishimori, H Michael Belmont, Robert Clancy, ANNE DAVIDSON, Matthias Kretzler, Michael Weisman, Celine C Berthier, Andrea Fava, Jennifer L Barnas, Jennifer H Anolik, Paul J Hoover, Deepak A Rao, Arnon Arazi, William Apruzzese, Fernanda Payan-Schober, Saori Sakaue, James Lederer, Michael Peters, Tony Jones, Jospeh Mears, Thomas M Eisenhaure, Siddarth Gurajala, Derek Fine, David A Hildeman, Steve Woodle, Maureen A McMahon, Jeffery Hodgin

Source: Lupus Science and Medicine, Vol 9, Iss Suppl 3 (2022)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/2053-8790

Access URL: https://doaj.org/article/1ff32e9bfffe45e7a30cc6f3a475aa6c

Seroprevalence of SARS-CoV-2 infection in Cincinnati Ohio USA from August to December 2020.

Authors: Greg Davis, Allen J York, Willis Clark Bacon, Suh-Chin Lin, Monica Malone McNeal, Alexander E Yarawsky, Joseph J Maciag, Jeanette L C Miller, Kathryn C S Locker, Michelle Bailey, Rebecca Stone, Michael Hall, Judith Gonzalez, Alyssa Sproles, E Steve Woodle, Kristen Safier, Kristine A Justus, Paul Spearman, Russell E Ware, Jose A Cancelas, Michael B Jordan, Andrew B Herr, David A Hildeman, Jeffery D Molkentin

Source: PLoS ONE, Vol 16, Iss 7, p e0254667 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/567754193c2d4608b6803f79e3e2b6ff

Olfactomedin 4 marks a subset of neutrophils in mice

Authors: Matthew N Alder, Jaya Mallela, Amy M Opoka, Patrick Lahni, David A Hildeman, Hector R Wong

Source: Innate Immunity, Vol 25 (2019)

Subject Terms: Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://doaj.org/toc/1753-4259; https://doaj.org/toc/1753-4267

Access URL: https://doaj.org/article/4a390860a5b242699e92f5d9ccf81b72

Tissue-specific control of latent CMV reactivation by regulatory T cells.

Authors: Maha Almanan, Jana Raynor, Allyson Sholl, Mei Wang, Claire Chougnet, Rhonda D Cardin, David A Hildeman

Source: PLoS Pathogens, Vol 13, Iss 8, p e1006507 (2017)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1006507&type=printable; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/044cf3d209704fe59f1edf663fbfbbf8

NKT cells contribute to basal IL-4 production but are not required to induce experimental asthma.

Authors: Christopher G McKnight, Suzanne C Morris, Charles Perkins, Zhenqi Zhu, David A Hildeman, Albert Bendelac, Fred D Finkelman

Source: PLoS ONE, Vol 12, Iss 11, p e0188221 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5705134?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/178aa329dc0a43b086794a21f0a0537c

Oncolytic HSV virotherapy in murine sarcomas differentially triggers an antitumor T-cell response in the absence of virus permissivity

Authors: Jennifer L Leddon, Chun-Yu Chen, Mark A Currier, Pin-Yi Wang, Francesca A Jung, Nicholas L Denton, Kevin M Cripe, Kellie B Haworth, Michael A Arnold, Amy C Gross, Timothy D Eubank, William F Goins, Joseph C Glorioso, Justus B Cohen, Paola Grandi, David A Hildeman, Timothy P Cripe

Source: Molecular Therapy: Oncolytics, Vol 1, Iss C (2014)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2372770516300043; https://doaj.org/toc/2372-7705

Access URL: https://doaj.org/article/bf8e7d0411ef44b882998c44c0e17aa8

IL-15 fosters age-driven regulatory T cell accrual in the face of declining IL-2 levels

Authors: Jana eRaynor, Allyson eSholl, David R. Plas, Philippe eBouillet, Claire A Chougnet, David A Hildeman

Source: Frontiers in Immunology, Vol 4 (2013)

Subject Terms: Aging, IL-2, Bim, CD25, Treg, IL-15, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00161/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/85157bf847c4483b8d20e0075840e5db

Growth factor independent-1 maintains Notch1-dependent transcriptional programming of lymphoid precursors.

Authors: James D Phelan, Ingrid Saba, Hui Zeng, Christian Kosan, Malynda S Messer, H Andre Olsson, Jennifer Fraszczak, David A Hildeman, Bruce J Aronow, Tarik Möröy, H Leighton Grimes

Source: PLoS Genetics, Vol 9, Iss 9, p e1003713 (2013)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3772063?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/ecc354ee1fdc4214a1d727d92fc781bf

RhoH regulates subcellular localization of ZAP-70 and Lck in T cell receptor signaling.

Authors: Hee-Don Chae, Jamie E Siefring, David A Hildeman, Yi Gu, David A Williams

Source: PLoS ONE, Vol 5, Iss 11, p e13970 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2980477?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b3a7cade93ee4d1b8322ff8db4555e69