The spatial landscape of cancer hallmarks reveals patterns of tumor ecological dynamics and drug sensitivity

Authors: Grande, Enrique, Alonso-Gordoa, Teresa, Álvarez-Maestro, Mario, Andrada, Elena, Azueta, Ainara, Javier Burgos, Raquel Benítez, Castellano, Daniel, Climent, M. Angel, Domínguez, Mario, Albert Font, Ignacio Durán, Galante, Isabel, Galván, Patricia, García, Juan F., García del Muro, Xavier, Guerrero-Ramos, Félix, Malats, Núria, Marqués, Miriam, Maroto, Pablo, Martínez de Villarreal, Jaime, Moreno-Oya, Ane, Paramio, Jesús M., Pinto, Alvaro, Prat, Aleix, Puente, Javier, Reig, Oscar, Real, Francisco X., Sibai, Mustafa ^{1, 2, 15}, Cervilla, Sergi ^{1, 15}, Grases, Daniela ^{1, 15}, Musulen, Eva ^{1, 3}, Lazcano, Rossana ⁴, Mo, Chia-Kuei ⁵, Davalos, Veronica ¹, Fortian, Arola ⁶, Bernat, Adrià ⁶, Romeo, Margarita ⁶, Tokheim, Collin ⁷, Barretina, Jordi ⁶, Lazar, Alexander J. ⁴, Ding, Li ⁵, Esteller, Manel ^{1, 10, 12, 13, 16}, Bailey, Matthew H. ^{14, 16}, Porta-Pardo, Eduard ^{1, 2, 16, 17, ∗}

Source: In Cell Reports 25 February 2025 44(2)

Cancer epigenetics in clinical practice

Authors: Davalos, Veronica, Esteller, Manel

Source: CA. 73(4):376-424

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186566320.0x000001&indx=1&recIds=ETOCvdc_100186566320.0x000001

The transcribed ultraconserved region uc.160+ enhances processing and A‐to‐I editing of the miR‐376 cluster: hypermethylation improves glioma prognosis

Authors: Soler, Marta, Davalos, Veronica, Sánchez‐Castillo, Anaís, Mora‐Martinez, Carlos, Setién, Fernando, Siqueira, Edilene, Castro de Moura, Manuel, Esteller, Manel, Guil, Sonia

Source: Molecular oncology. 16(3):648-664

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100139827418.0x000001&indx=1&recIds=ETOCvdc_100139827418.0x000001

Epigenetic Profiling and Response to CD19 Chimeric Antigen Receptor T-Cell Therapy in B-Cell Malignancies

Authors: Garcia-Prieto, Carlos A, Villanueva, Lorea, Bueno-Costa, Alberto, Davalos, Veronica, González-Navarro, Europa Azucena, Juan, Manel, Urbano-Ispizua, Álvaro, Delgado, Julio, Ortiz-Maldonado, Valentín, del Bufalo, Francesca, Locatelli, Franco, Quintarelli, Concetta, Sinibaldi, Matilde, Soler, Marta, Castro de Moura, Manuel, Ferrer, Gerardo, Urdinguio, Rocio G, Fernandez, Agustin F, Fraga, Mario F, Bar, Diana, Meir, Amilia, Itzhaki, Orit, Besser, Michal J, Avigdor, Abraham, Jacoby, Elad, Esteller, Manel

Source: Journal of the National Cancer Institute. 114(3):436-445

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100144309116.0x000001&indx=1&recIds=ETOCvdc_100144309116.0x000001

Epigenetic activation of antiviral sensors and effectors of interferon response pathways during SARS-CoV-2 infection

Authors: Bińkowski, Jan, Taryma-Leśniak, Olga, Łuczkowska, Karolina, Niedzwiedź, Anna, Lechowicz, Kacper, Strapagiel, Dominik, Jarczak, Justyna, Davalos, Veronica, Pujol, Aurora, Esteller, Manel, Kotfis, Katarzyna, Machaliński, Bogusław, Parczewski, Miłosz, Wojdacz, Tomasz K.

Source: In Biomedicine & Pharmacotherapy September 2022 153

Epigenetic profiling linked to multisystem inflammatory syndrome in children (MIS-C): A multicenter, retrospective study

Authors: Davalos, Veronica, García-Prieto, Carlos A., Ferrer, Gerardo, Aguilera-Albesa, Sergio, Valencia-Ramos, Juan, Rodríguez-Palmero, Agustí, Ruiz, Montserrat, Planas-Serra, Laura, Jordan, Iolanda, Alegría, Iosune, Flores-Pérez, Patricia, Cantarín, Verónica, Fumadó, Victoria, Viadero, Maria Teresa, Rodrigo, Carlos, Méndez-Hernández, Maria, López-Granados, Eduardo, Colobran, Roger, Rivière, Jacques G., Soler-Palacín, Pere, Pujol, Aurora, Esteller, Manel

Source: In eClinicalMedicine August 2022 50

Epigenetic loss of the transfer RNA-modifying enzyme TYW2 induces ribosome frameshifts in colon cancer

Authors: Rosselló-Tortella, Margalida, Llinàs-Arias, Pere, Sakaguchi, Yuriko, Davalos, Veronica, Setien, Fernando, Calleja-Cervantes, Maria E., Pin˜eyro, David, Martínez-Gómez, Jesús, Guil, Sonia, Joshi, Ricky, Villanueva, Alberto, Suzuki, Tsutomu, Esteller, Manel

Source: Proceedings of the National Academy of Sciences of the United States of America, 2020 Aug . 117(34), 20785-20793.

Access URL: https://www.jstor.org/stable/26969050

Epigenome-wide association study of COVID-19 severity with respiratory failure

Authors: Castro de Moura, Manuel, Davalos, Veronica, Planas-Serra, Laura, Alvarez-Errico, Damiana, Arribas, Carles, Ruiz, Montserrat, Aguilera-Albesa, Sergio, Troya, Jesús, Valencia-Ramos, Juan, Vélez-Santamaria, Valentina, Rodríguez-Palmero, Agustí, Villar-Garcia, Judit, Horcajada, Juan P., Albu, Sergiu, Casasnovas, Carlos, Rull, Anna, Reverte, Laia, Dietl, Beatriz, Dalmau, David, Arranz, Maria J., Llucià-Carol, Laia, Planas, Anna M., Pérez-Tur, Jordi, Fernandez-Cadenas, Israel, Villares, Paula, Tenorio, Jair, Colobran, Roger, Martin-Nalda, Andrea, Soler-Palacin, Pere, Vidal, Francesc, Pujol, Aurora, Esteller, Manel

Source: In eBioMedicine April 2021 66

Epigenetic loss of m1A RNA demethylase ALKBH3 in Hodgkin lymphoma targets collagen, conferring poor clinical outcome

Authors: Esteve-Puig, Rosaura, Climent, Fina, Piñeyro, David, Domingo-Domènech, Eva, Davalos, Veronica, Encuentra, Maite, Rea, Anna, Espejo-Herrera, Nadia, Soler, Marta, Lopez, Miguel, Ortiz-Barahona, Vanessa, Tapia, Gustavo, Navarro, José-Tomás, Cid, Joan, Farré, Lourdes, Villanueva, Alberto, Casanova, Isolda, Mangues, Ramon, Santamarina-Ojeda, Pablo, Fernández, Agustín F., Fraga, Mario F., Piris, Miguel Angel, Kol, Nitzan, Avrahami, Chen, Moshitch-Moshkovitz, Sharon, Rechavi, Gideon, Sureda, Anna ^*, Esteller, Manel ^*

Source: In Blood 18 February 2021 137(7):994-999

Epigenetic prediction of response to anti-PD-1 treatment in non-small-cell lung cancer: a multicentre, retrospective analysis

Authors: Duruisseaux, Michäel, Martínez-Cardús, Anna, Calleja-Cervantes, Maria E, Moran, Sebastian, Castro de Moura, Manuel, Davalos, Veronica, Piñeyro, David, Sanchez-Cespedes, Montse, Girard, Nicolas, Brevet, Marie, Giroux-Leprieur, Etienne, Dumenil, Coraline, Pradotto, Monica, Bironzo, Paolo, Capelletto, Enrica, Novello, Silvia, Cortot, Alexis, Copin, Marie-Christine, Karachaliou, Niki, Gonzalez-Cao, Maria, Peralta, Sergio, Montuenga, Luis M, Gil-Bazo, Ignacio, Baraibar, Iosune, Lozano, Maria D, Varela, Mar, Ruffinelli, Jose C, Palmero, Ramon, Nadal, Ernest, Moran, Teresa, Perez, Lidia, Ramos, Immaculada, Xiao, Qingyang, Fernandez, Agustin F, Fraga, Mario F, Gut, Marta, Gut, Ivo, Teixidó, Cristina, Vilariño, Noelia, Prat, Aleix, Reguart, Noemi, Benito, Amparo, Garrido, Pilar, Barragan, Isabel, Emile, Jean-François, Rosell, Rafael, Brambilla, Elisabeth, Esteller, Manel

Source: In The Lancet Respiratory Medicine October 2018 6(10):771-781

Refinement of computational identification of somatic copy number alterations using DNA methylation microarrays illustrated in cancers of unknown primary.

Authors: Blecua, Pedro¹ (AUTHOR), Davalos, Veronica¹ (AUTHOR), Villasante, Izar de¹ (AUTHOR), Merkel, Angelika¹ (AUTHOR), Musulen, Eva^1,2 (AUTHOR), Coll-SanMartin, Laia¹ (AUTHOR), Esteller, Manel^1,3,4,5 (AUTHOR) mesteller@carrerasresearch.org

Source: Briefings in Bioinformatics. Sep2022, Vol. 23 Issue 5, p1-9. 9p.

Subject Terms: *CANCER of unknown primary origin, *DNA methylation, *DNA microarrays, *DNA, *FLUORESCENCE in situ hybridization, *GENE amplification, *METHYLATION, *RIBOSOMAL DNA

Epigenetic inactivation of the splicing RNA-binding protein CELF2 in human breast cancer

Authors: Piqué, Laia, Martinez de Paz, Alexia, Piñeyro, David, Martínez-Cardús, Anna, Castro de Moura, Manuel, Llinàs-Arias, Pere, Setien, Fernando, Gomez-Miragaya, Jorge, Gonzalez-Suarez, Eva, Sigurdsson, Stefan, Jonasson, Jon, Villanueva, Alberto, Vidal, August, Davalos, Veronica, Esteller, Manel

Source: Oncogene. 38(45):7106-7112

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190905796.0x000001&indx=1&recIds=ETOCvdc_100190905796.0x000001

Look-alike humans identified by facial recognition algorithms show genetic similarities

Authors: Joshi, Ricky S., Rigau, Maria, García-Prieto, Carlos A., Castro de Moura, Manuel, Piñeyro, David, Moran, Sebastian, Davalos, Veronica, Carrión, Pablo, Ferrando-Bernal, Manuel, Olalde, Iñigo, Lalueza-Fox, Carles, Navarro, Arcadi, Fernández-Tena, Carles, Aspandi, Decky, Sukno, Federico M., Binefa, Xavier, Valencia, Alfonso, Esteller, Manel

Source: Cell reports. 40(8)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173201487.0x000001&indx=1&recIds=ETOCvdc_100173201487.0x000001

The Epigenomic Revolution in Breast Cancer: From Single-Gene to Genome-Wide Next-Generation Approaches

Authors: Davalos, Veronica, Martinez-Cardus, Anna, Esteller, Manel

Source: In The American Journal of Pathology October 2017 187(10):2163-2174

A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis

Authors: Agrawal, Praveen, Fontanals-Cirera, Barbara, Sokolova, Elena, Jacob, Samson, Vaiana, Christopher A., Argibay, Diana, Davalos, Veronica, McDermott, Meagan, Nayak, Shruti, Darvishian, Farbod, Castillo, Mireia, Ueberheide, Beatrix, Osman, Iman, Fenyö, David, Mahal, Lara K., Hernando, Eva

Source: In Cancer Cell 12 June 2017 31(6):804-819

DNA methylation profiling of myelodysplastic syndromes and clinical response to azacitidine: A multicentre retrospective study.

Authors: Noguera‐Castells, Aleix, Campillo‐Marcos, Ignacio, Davalos, Veronica, García‐Prieto, Carlos A., Valcárcel, David, Molero, Antonieta, Palomo, Laura, Gattermann, Norbert, Wulfert, Michael, Chaparro‐González, Lorea, Solé, Francesc, Cabezón, Marta, Jiménez‐Lorenzo, María J., Xicoy, Blanca, Zamora, Lurdes, De Stefano, Alessia, Casalin, Irene, Finelli, Carlo, Follo, Matilde Y., Esteller, Manel

Source: British Journal of Haematology; May2024, Vol. 204 Issue 5, p1838-1843, 6p

Subject Terms: MYELODYSPLASTIC syndromes, DNA methylation, AZACITIDINE, RETROSPECTIVE studies, EPIGENOMICS, BIOMARKERS

Epigenetic Fingerprint of the SARS-CoV-2 Infection in the Lung of Lethal COVID-19.

Authors: Noguera-Castells, Aleix, Parra, Jerónimo, Davalos, Veronica, García-Prieto, Carlos A., Veselinova, Yoana, Pérez-Miés, Belén, Caniego-Casas, Tamara, Palacios, José, Saenz-Sardà, Xavier, Englund, Elisabet, Musulen, Eva, Esteller, Manel

Source: CHEST; Apr2024, Vol. 165 Issue 4, p820-824, 5p

Subject Terms: LUNG infections, SARS-CoV-2, COVID-19, EPIGENETICS

Limited miR-17-92 overexpression drives hematologic malignancies

Authors: Danielson, Laura S., Reavie, Linsey, Coussens, Marc, Davalos, Veronica, Castillo-Martin, Mireia, Guijarro, Maria V., Coffre, Maryaline, Cordon-Cardo, Carlos, Aifantis, Iannis, Ibrahim, Sherif, Liu, Cynthia, Koralov, Sergei B., Hernando, Eva

Source: In Leukemia Research March 2015 39(3):335-341

The Breast Cancer Oncogene EMSY Represses Transcription of Antimetastatic microRNA miR-31

Authors: Viré, Emmanuelle, Curtis, Christina, Davalos, Veronica, Git, Anna, Robson, Samuel, Villanueva, Alberto, Vidal, August, Barbieri, Isaia, Aparicio, Samuel, Esteller, Manel, Caldas, Carlos, Kouzarides, Tony

Source: In Molecular Cell 6 March 2014 53(5):806-818

Cancer metastasis under the magnifying glass of epigenetics and epitranscriptomics.

Authors: Janin, Maxime, Davalos, Veronica, Esteller, Manel

Source: Cancer & Metastasis Reviews; Dec2023, Vol. 42 Issue 4, p1071-1112, 42p