Melanoma risk during immunomodulating treatment

Authors: Zheng, Yixuan James, Ho, Wilson, Sanlorenzo, Martina, Vujic, Igor, Daud, Adil, Algazi, Alain, Rappersberger, Klemens, Ortiz-Urda, Susana

Source: Melanoma research. 32(6):411-418

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TCR-sequencing in cancer and autoimmunity: barcodes and beyond

Authors: Pauken, Kristen E., Lagattuta, Kaitlyn A., Lu, Benjamin Y., Lucca, Liliana E., Daud, Adil I., Hafler, David A., Kluger, Harriet M., Raychaudhuri, Soumya, Sharpe, Arlene H.

Source: Trends in immunology. 43(3):180-194

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100156126544.0x000001&indx=1&recIds=ETOCvdc_100156126544.0x000001

Amplification of the CXCR3/CXCL9 axis via intratumoral electroporation of plasmid CXCL9 synergizes with plasmid IL-12 therapy to elicit robust anti-tumor immunity

Authors: Lee, Jack Y., Nguyen, Bianca, Mukhopadhyay, Anandaroop, Han, Mia, Zhang, Jun, Gujar, Ravindra, Salazar, Jon, Hermiz, Reneta, Svenson, Lauren, Browning, Erica, Lyerly, H. Kim, Canton, David A., Fisher, Daniel, Daud, Adil, Algazi, Alain, Skitzki, Joseph, Twitty, Christopher G.

Source: In Molecular Therapy - Oncolytics 16 June 2022 25:174-188

Discovering dominant tumor immune archetypes in a pan-cancer census

Authors: Spitzer, Matthew, Fong, Lawrence, Nelson, Amanda, Kumar, Raj, Lee, Justin, Burra, Arun, Hsu, Joy, Hackett, Caroline, Tolentino, Karen, Sjarif, Jasmine, Johnson, Peter, Shao, Evans, Abrau, Darrell, Lupin, Leonard, Shaw, Cole, Collins, Zachary, Lea, Tasha, Corvera, Carlos, Nakakura, Eric, Carnevale, Julia, Alvarado, Michael, Loo, Kimberley, Chen, Lawrence, Chow, Melissa, Grandis, Jennifer, Ryan, Will, El-Sayed, Ivan, Jablons, David, Woodard, Gavitt, Meng, Maxwell W., Porten, Sima P., Okada, Hideho, Tempero, Margaret, Ko, Andrew, Kirkwood, Kim, Vandenberg, Scott, Guevarra, Denise, Oropeza, Erica, Cyr, Chris, Glenn, Pat, Bolen, Jennifer, Morton, Amanda, Eckalbar, Walter, Combes, Alexis J., Samad, Bushra, Tsui, Jessica, Chew, Nayvin W., Yan, Peter, Reeder, Gabriella C., Kushnoor, Divyashree, Shen, Alan, Davidson, Brittany, Barczak, Andrea J., Adkisson, Michael, Edwards, Austin, Naser, Mohammad, Barry, Kevin C., Courau, Tristan, Hammoudi, Taymour, Argüello, Rafael J., Rao, Arjun Arkal, Olshen, Adam B., Cai, Cathy, Zhan, Jenny, Davis, Katelyn C., Kelley, Robin K., Chapman, Jocelyn S., Atreya, Chloe E., Patel, Amar, Daud, Adil I., Ha, Patrick, Diaz, Aaron A., Kratz, Johannes R., Collisson, Eric A., Fragiadakis, Gabriela K., Erle, David J., Boissonnas, Alexandre, Asthana, Saurabh, Chan, Vincent, Krummel, Matthew F.

Source: In Cell 6 January 2022 185(1):184-203

Should Sentinel Lymph Node Biopsy Status Guide Adjuvant Radiation Therapy in Patients With Merkel Cell Carcinoma?

Authors: Ahmad, Tessnim R., Vasudevan, Harish N., Lazar, Ann A., Chan, Jason W., George, Jonathan R., Alvarado, Michael D., Yu, Siegrid S., Daud, Adil, Yom, Sue S.

Source: In Advances in Radiation Oncology November-December 2021 6(6)

Long-term outcomes in patients with advanced melanoma who had initial stable disease with pembrolizumab in KEYNOTE-001 and KEYNOTE-006

Authors: Hamid, Omid, Robert, Caroline, Daud, Adil, Carlino, Matteo S., Mitchell, Tara C., Hersey, Peter, Schachter, Jacob, Long, Georgina V., Hodi, F. Stephen, Wolchok, Jedd D., Arance, Ana, Grob, Jean Jacques, Joshua, Anthony M., Weber, Jeffrey S., Mortier, Laurent, Jensen, Erin, Diede, Scott J., Moreno, Blanca Homet, Ribas, Antoni

Source: In European Journal of Cancer November 2021 157:391-402

Long-term safety of pembrolizumab monotherapy and relationship with clinical outcome: A landmark analysis in patients with advanced melanoma

Authors: Robert, Caroline, Hwu, Wen-Jen, Hamid, Omid, Ribas, Antoni, Weber, Jeffrey S., Daud, Adil I., Hodi, F. Stephen, Wolchok, Jedd D., Mitchell, Tara C., Hersey, Peter, Dronca, Roxana, Joseph, Richard W., Boutros, Celine, Min, Le, Long, Georgina V., Schachter, Jacob, Puzanov, Igor, Dummer, Reinhard, Lin, Jianxin, Ibrahim, Nageatte, Diede, Scott J., Carlino, Matteo S., Joshua, Anthony M.

Source: In European Journal of Cancer February 2021 144:182-191

Pulsed Electric Fields in Oncology: A Snapshot of Current Clinical Practices and Research Directions from the 4th World Congress of Electroporation.

Authors: Campana, Luca G.¹ (AUTHOR) francesco.lancellotti@mft.nhs.uk, Daud, Adil² (AUTHOR) adil.daud@ucsf.edu, Lancellotti, Francesco¹ (AUTHOR), Arroyo, Julio P.³ (AUTHOR) jparroyo@vt.edu, Davalos, Rafael V.^3,4 (AUTHOR) davalos@vt.edu, Di Prata, Claudia⁵ (AUTHOR) claudiadipratamd@gmail.com, Gehl, Julie^6,7 (AUTHOR) kgeh@regionsjaelland.dk

Source: Cancers. Jul2023, Vol. 15 Issue 13, p3340. 42p.

Subject Terms: *CANCER chemotherapy, *CONFERENCES & conventions, *ELECTROMAGNETIC fields, *ELECTROPORATION, *INTERPROFESSIONAL relations, *PHYSICIAN practice patterns, *GENETIC techniques, *ONCOLOGY, *MEDICAL research

Pembrolizumab versus ipilimumab in advanced melanoma (KEYNOTE-006): post-hoc 5-year results from an open-label, multicentre, randomised, controlled, phase 3 study

Authors: Robert, Caroline ^*, Ribas, Antoni, Schachter, Jacob, Arance, Ana, Grob, Jean-Jacques, Mortier, Laurent, Daud, Adil, Carlino, Matteo S, McNeil, Catriona M, Lotem, Michal, Larkin, James M G, Lorigan, Paul, Neyns, Bart, Blank, Christian U, Petrella, Teresa M, Hamid, Omid, Su, Shu-Chih, Krepler, Clemens, Ibrahim, Nageatte, Long, Georgina V

Source: In The Lancet Oncology September 2019 20(9):1239-1251

Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium

Authors: Andrews, Miles C, Berry, Donald A, Block, Matthew S, Boland, Genevieve M, Bollin, Kathryn B, Carlino, Matteo S, Carvajal, Richard D, Cohen, Jonathan, Davar, Diwakar, Delman, Keith A, Dummer, Reinhard, Farwell, Michael D, Fisher, David E, Fusi, Alberto, Glitza, Isabella C, de Gruijl, Tanja D, Gyorki, David E, Hauschild, Axel, Hieken, Tina J, Larkin, James, Lawson, David H, Lebbe, Celeste, Lee, Jeffrey E, Lowe, Michael C, Luke, Jason J, McArthur, Grant A, McDermott, David F, McQuade, Jennifer L, Mitchell, Tara C, Petrella, Teresa M, Prieto, Peter A, Puzanov, Igor, Robert, Caroline, Salama, April K, Sandhu, Shaneen, Schadendorf, Dirk, Shoushtari, Alexander N, Sosman, Jeffrey A, Swetter, Susan M, Tanabe, Ken K, Turajlic, Samra, Tyler, Douglas S, Woodman, Scott E, Wright, Frances C, Zager, Jonathan S, Amaria, Rodabe N, Menzies, Alexander M, Burton, Elizabeth M, Scolyer, Richard A, Tetzlaff, Michael T, Antdbacka, Robert, Ariyan, Charlotte, Bassett, Roland, Carter, Brett, Daud, Adil, Faries, Mark, Fecher, Leslie A, Flaherty, Keith T, Gershenwald, Jeffrey E, Hamid, Omid, Hong, Angela, Kirkwood, John M, Lo, Serigne, Margolin, Kim, Messina, Jane, Postow, Michael A, Rizos, Helen, Ross, Merrick I, Rozeman, Elisa A, Saw, Robyn P M, Sondak, Vernon, Sullivan, Ryan J, Taube, Janis M, Thompson, John F, van de Wiel, Bart A, Eggermont, Alexander M, Davies, Michael A, Ascierto, Paolo A, Spillane, Andrew J, van Akkooi, Alexander C J, Wargo, Jennifer A, Blank, Christian U, Tawbi, Hussein A, Long, Georgina V

Source: In The Lancet Oncology July 2019 20(7):e378-e389

Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity

Authors: Binnewies, Mikhail, Mujal, Adriana M., Pollack, Joshua L., Combes, Alexis J., Hardison, Emily A., Barry, Kevin C., Tsui, Jessica, Ruhland, Megan K., Kersten, Kelly, Abushawish, Marwan A., Spasic, Marko, Giurintano, Jonathan P., Chan, Vincent, Daud, Adil I., Ha, Patrick, Ye, Chun J., Roberts, Edward W., Krummel, Matthew F.

Source: In Cell 18 April 2019 177(3):556-571

Tumor Immune Profiling-Based Neoadjuvant Immunotherapy for Locally Advanced Melanoma

Authors: Levine, Lauren S., Mahuron, Kelly M., Tsai, Katy K., Wu, Clinton, Mattis, Daiva M., Pauli, Mariela L., Oglesby, Arielle, Lee, James C., Spitzer, Matthew H., Krummel, Matthew F., Algazi, Alain P., Rosenblum, Michael D., Alvarado, Michael, Daud, Adil I.

Source: Annals of surgical oncology. 27(11):4122-4130

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Clonal Deletion of Tumor-Specific T Cells by Interferon-γ Confers Therapeutic Resistance to Combination Immune Checkpoint Blockade

Authors: Pai, Chien-Chun Steven, Huang, John T., Lu, Xiaoqing, Simons, Donald M., Park, Chanhyuk, Chang, Anthony, Tamaki, Whitney, Liu, Eric, Roybal, Kole T., Seagal, Jane, Chen, Mingyi, Hagihara, Katsunobu, Wei, Xiao X., DuPage, Michel, Kwek, Serena S., Oh, David Y., Daud, Adil, Tsai, Katy K., Wu, Clint, Zhang, Li, Fasso, Marcella, Sachidanandam, Ravi, Jayaprakash, Anitha, Lin, Ingrid, Casbon, Amy-Jo, Kinsbury, Gillian A., Fong, Lawrence

Source: In Immunity 19 February 2019 50(2):477-492

Successful Anti-PD-1 Cancer Immunotherapy Requires T Cell-Dendritic Cell Crosstalk Involving the Cytokines IFN-γ and IL-12

Authors: Garris, Christopher S., Arlauckas, Sean P., Kohler, Rainer H., Trefny, Marcel P., Garren, Seth, Piot, Cécile, Engblom, Camilla, Pfirschke, Christina, Siwicki, Marie, Gungabeesoon, Jeremy, Freeman, Gordon J., Warren, Sarah E., Ong, SuFey, Browning, Erica, Twitty, Christopher G., Pierce, Robert H., Le, Mai H., Algazi, Alain P., Daud, Adil I., Pai, Sara I., Zippelius, Alfred, Weissleder, Ralph, Pittet, Mikael J.

Source: In Immunity 18 December 2018 49(6):1148-1161

Outcomes by line of therapy and programmed death ligand 1 expression in patients with advanced melanoma treated with pembrolizumab or ipilimumab in KEYNOTE-006: A randomised clinical trial

Authors: Carlino, Matteo S., Long, Georgina V., Schadendorf, Dirk, Robert, Caroline, Ribas, Antoni, Richtig, Erika, Nyakas, Marta, Caglevic, Christian, Tarhini, Ahmed, Blank, Christian, Hoeller, Christoph, Bar-Sela, Gil, Barrow, Catherine, Wolter, Pascal, Zhou, Honghong, Emancipator, Kenneth, Jensen, Erin H., Ebbinghaus, Scot, Ibrahim, Nageatte, Daud, Adil

Source: In European Journal of Cancer September 2018 101:236-243

Distinguishing between help and harm: Helper T cell subsets and immune-related adverse events.

Authors: Haugh, Alexandra M.¹, Daud, Adil I.² adil.daud@ucsf.edu

Source: Journal of Clinical Investigation. 10/15/2024, Vol. 134 Issue 20, p1-3. 3p.

Subject Terms: *T helper cells, *DRUG side effects, *IMMUNE checkpoint inhibitors, *T cells, *CELL populations

Intratumoral and Combination Therapy in Melanoma and Other Skin Cancers

Authors: Oglesby, Arielle, Algazi, Alain P., Daud, Adil I.

Source: American journal of clinical dermatology. 20(6):781-796

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100130230700.0x000001&indx=1&recIds=ETOCvdc_100130230700.0x000001

A dual pathway inhibition strategy using BKM120 combined with vemurafenib is poorly tolerated in BRAF V600E/K mutant advanced melanoma

Authors: Algazi, Alain Patrick, Rotow, Julia, Posch, Christian, Ortiz‐Urda, Susana, Pelayo, Alyson, Munster, Pamela N., Daud, Adil

Source: Pigment cell & melanoma research. 32(4):603-606

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100090983463.0x000001&indx=1&recIds=ETOCvdc_100090983463.0x000001

Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium

Authors: Amaria, Rodabe N, Menzies, Alexander M, Burton, Elizabeth M, Scolyer, Richard A, Tetzlaff, Michael T, Antdbacka, Robert, Ariyan, Charlotte, Bassett, Roland, Carter, Brett, Daud, Adil, Faries, Mark, Fecher, Leslie A, Flaherty, Keith T, Gershenwald, Jeffrey E, Hamid, Omid, Hong, Angela, Kirkwood, John M, Lo, Serigne, Margolin, Kim, Messina, Jane, Postow, Michael A, Rizos, Helen, Ross, Merrick I, Rozeman, Elisa A, Saw, Robyn P M, Sondak, Vernon, Sullivan, Ryan J, Taube, Janis M, Thompson, John F, van de Wiel, Bart A, Eggermont, Alexander M, Davies, Michael A, Ascierto, Paolo A, Spillane, Andrew J, van Akkooi, Alexander C J, Wargo, Jennifer A, Blank, Christian U, Tawbi, Hussein A, Long, Georgina V

Source: Lancet oncology. 20(7):e378-e389

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083873857.0x000001&indx=1&recIds=ETOCvdc_100083873857.0x000001

An analysis of genetic heterogeneity in untreated cancers

Authors: Reiter, Johannes, Baretti, Marina, Gerold, Jeffrey, Makohon-Moore, Alvin, Daud, Adil, Iacobuzio-Donahue, Christine, Azad, Nilofer, Kinzler, Kenneth, Nowak, Martin, Vogelstein, Bert

Source: Nature reviews.Cancer. 19(11):639-650

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190866283.0x000001&indx=1&recIds=ETOCvdc_100190866283.0x000001