Engineering Lipid Nanoparticles to Enhance Intracellular Delivery of Transforming Growth Factor-Beta siRNA (siTGF-β1) via Inhalation for Improving Pulmonary Fibrosis Post-Bleomycin Challenge

Authors: Xu Deng, Yingjie Yang, Liming Gan, Xinliu Duan, Xiwei Wang, Jingyan Zhang, Aiping Wang, Anan Zhang, Zhizhao Yuan, Daquan Chen, Aiping Zheng

Source: Pharmaceutics, Vol 17, Iss 2, p 157 (2025)

Subject Terms: lipid nanoparticles (LNPs), siRNA delivery, design of experiments (DOE), pulmonary fibrosis (PF), transforming growth factor β1 (TGF-β1), Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/17/2/157; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/99ea563db2844300b219bb4efa148c7f

Novel dual CAFs and tumour cell targeting pH and ROS dual sensitive micelles for targeting delivery of paclitaxel to liver cancer

Authors: Chunjing Guo, Wei Zhang, Qiaoyun Zhang, Yanguo Su, Xiaoya Hou, Qiang Chen, Huimin Guo, Ming Kong, Daquan Chen

Source: Artificial Cells, Nanomedicine, and Biotechnology, Vol 51, Iss 1, Pp 170-179 (2023)

Subject Terms: Tumour-associated fibroblasts, deep penetration, dual targeting, ROS response, anti-fibrosis, nanoparticles, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

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Relation: https://doaj.org/toc/2169-1401; https://doaj.org/toc/2169-141X

Access URL: https://doaj.org/article/54bdfd29264147e58766e6b53d80e46b

α-Lipoic acid loaded hollow gold nanoparticles designed for osteoporosis treatment: preparation, characterization and in vitro evaluation

Authors: Yanhai Xi, Wenming Pan, Yanyan Liu, Ji Liu, Guohua Xu, Yanguo Su, Daquan Chen, Xiaojian Ye

Source: Artificial Cells, Nanomedicine, and Biotechnology, Vol 51, Iss 1, Pp 131-138 (2023)

Subject Terms: α-Lipoic acid, hollow gold nanoparticles, antioxidant, ROS, osteoporosis, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

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Relation: https://doaj.org/toc/2169-1401; https://doaj.org/toc/2169-141X

Access URL: https://doaj.org/article/8c4a935072064796a5e270a61260dd30

CD47KO/CRT dual-bioengineered cell membrane-coated nanovaccine combined with anti-PD-L1 antibody for boosting tumor immunotherapy

Authors: Shengyang Liu, Jiayan Wu, Yuanji Feng, Xiaoya Guo, Tong Li, Meng Meng, Jie Chen, Daquan Chen, Huayu Tian

Source: Bioactive Materials, Vol 22, Iss , Pp 211-224 (2023)

Subject Terms: CRISPR–Cas9, Dual-bioengineered cell membrane, Immune checkpoint blockade, Nanovaccine, Tumor immunotherapy, Materials of engineering and construction. Mechanics of materials, TA401-492, Biology (General), QH301-705.5

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Relation: http://www.sciencedirect.com/science/article/pii/S2452199X22004133; https://doaj.org/toc/2452-199X

Access URL: https://doaj.org/article/e6331b4abd6c427683146e54c089922c

Dextran sulfate-based MMP-2 enzyme-sensitive SR-A receptor targeting nanomicelles for the treatment of rheumatoid arthritis

Authors: Caiwei Yu, Hui Liu, Chunjing Guo, Qiang Chen, Yanguo Su, Huimin Guo, Xiaoya Hou, Feng Zhao, Huaying Fan, Hui Xu, Yan Zhao, Xiaofeng Mu, Guohua Wang, Haiyu Xu, Daquan Chen

Source: Drug Delivery, Vol 29, Iss 1, Pp 454-465 (2022)

Subject Terms: rheumatoid arthritis, celastrol, dextran sulfate, mmp-2 response, targeting drug delivery system, Therapeutics. Pharmacology, RM1-950

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Relation: https://doaj.org/toc/1071-7544; https://doaj.org/toc/1521-0464

Access URL: https://doaj.org/article/dd9a8da6634c454d8fb2d54ad7859901

Hypoxia responsive nano-drug delivery system based on angelica polysaccharide for liver cancer therapy

Authors: Xue Liu, Zhenfeng Wu, Chunjing Guo, Huimin Guo, Yanguo Su, Qiang Chen, Changgang Sun, Qingming Liu, Daquan Chen, Hongjie Mu

Source: Drug Delivery, Vol 29, Iss 1, Pp 138-148 (2022)

Subject Terms: hypoxia responsive, angelica polysaccharide, micelle, liver cancer, ferroptosis, Therapeutics. Pharmacology, RM1-950

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Relation: https://doaj.org/toc/1071-7544; https://doaj.org/toc/1521-0464

Access URL: https://doaj.org/article/6d01967aeb564bc0b3ad1630427e9dba

Complex polymeric nanomicelles co-delivering doxorubicin and dimethoxycurcumin for cancer chemotherapy

Authors: Muhammad Sohail, Bin Yu, Zheng Sun, Jiali Liu, Yanli Li, Feng Zhao, Daquan Chen, Xin Yang, Hui Xu

Source: Drug Delivery, Vol 29, Iss 1, Pp 1523-1535 (2022)

Subject Terms: Complex polymeric nanomicelles, doxorubicin, dimethoxycurcumin, combinational cancer chemotherapy, Therapeutics. Pharmacology, RM1-950

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Relation: https://doaj.org/toc/1071-7544; https://doaj.org/toc/1521-0464

Access URL: https://doaj.org/article/5652d8133ae84be595ec3c676e3091aa

A novel saponin liposomes based on the couplet medicines of Platycodon grandiflorum–Glycyrrhiza uralensis for targeting lung cancer

Authors: Chunjing Guo, Yanguo Su, Hui Wang, Min Cao, Ningning Diao, Zhongxin Liu, Daquan Chen, Ming Kong

Source: Drug Delivery, Vol 29, Iss 1, Pp 2743-2750 (2022)

Subject Terms: Couplet medicines, liposomes, synergistic therapy, platycodin, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1071-7544; https://doaj.org/toc/1521-0464

Access URL: https://doaj.org/article/aad26bd201184cf2b995954b615228eb

Dose escalation biodistribution, positron emission tomography/computed tomography imaging and dosimetry of a highly specific radionuclide-labeled non-blocking nanobody

Authors: Yanling Yang, Chao Wang, Yan Wang, Yan Sun, Xing Huang, Minzhou Huang, Hui Xu, Huaying Fan, Daquan Chen, Feng Zhao

Source: EJNMMI Research, Vol 11, Iss 1, Pp 1-10 (2021)

Subject Terms: Nb109, PD-L1, PET imaging, nanobody, Tracer, 68Ga, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: https://doaj.org/toc/2191-219X

Access URL: https://doaj.org/article/7c63a243a80746918ff5bf1304bef3db

Effect of Angelica polysaccharide on mouse myeloid-derived suppressor cells

Authors: Jie Shen, Mengyu Zhang, Ke Zhang, Yahan Qin, Meifang Liu, Shujuan Liang, Daquan Chen, Meiyu Peng

Source: Frontiers in Immunology, Vol 13 (2022)

Subject Terms: Angelica polysaccharide, myeloid-derived suppressor cells, mannose receptor, proliferation, differentiation, immunosuppression, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2022.989230/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/4db6eeee9d9448fe950561fc306d2138

A DM1-doped porous gold nanoshell system for NIR accelerated redox-responsive release and triple modal imaging guided photothermal synergistic chemotherapy

Authors: Pengcheng Xu, Ru Wang, Wenqian Yang, Yanyan Liu, Dongsheng He, Zixuan Ye, Daquan Chen, Yuan Ding, Jiasheng Tu, Yan Shen

Source: Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-19 (2021)

Subject Terms: Porous gold nanoshell, Maytansine, Chemo-thermal therapy, Multimodal imaging, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/ddfa2b6a30914fb4b046b01bebe3d01a

3D Printing Technology Based on Versatile Gelatin-Carrageenan Gel System for Drug Formulations

Authors: En Liang, Zengming Wang, Xiang Li, Shanshan Wang, Xiaolu Han, Daquan Chen, Aiping Zheng

Source: Pharmaceutics, Vol 15, Iss 4, p 1218 (2023)

Subject Terms: 3D printing, pediatric medicines, printability, rheological characteristics, microstructure, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/4/1218; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/cf1986ac9cb04748bbac43d05d9cefb8

Correction to: A DM1-doped porous gold nanoshell system for NIR accelerated redox-responsive release and triple modal imaging guided photothermal synergistic chemotherapy

Authors: Pengcheng Xu, Ru Wang, Wenqian Yang, Yanyan Liu, Dongsheng He, Zixuan Ye, Daquan Chen, Yuan Ding, Jiasheng Tu, Yan Shen

Source: Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-3 (2021)

Subject Terms: Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/25ff094e71c64edfa9f398d1585a7230

Optimization, characterization and evaluation of ZnO/polyvinylidene fluoride nanocomposites for orthopedic applications: improved antibacterial ability and promoted osteoblast growth

Authors: Yanhai Xi, Wenming Pan, Dan Xi, Xue Liu, Jiangmin Yu, Mintao Xue, Ning Xu, Jiankun Wen, Weiheng Wang, Hailong He, Yanyan Liu, Yue He, Chunjing Guo, Daquan Chen, Xiaojian Ye

Source: Drug Delivery, Vol 27, Iss 1, Pp 1378-1385 (2020)

Subject Terms: electrospinning, zinc oxide/polyvinylidene, nanoparticles, fluoride composite fiber membrane, piezoelectricity, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1071-7544; https://doaj.org/toc/1521-0464

Access URL: https://doaj.org/article/babc2184a5f246a0b52c51109005504a

Highly loaded deoxypodophyllotoxin nano-formulation delivered by methoxy polyethylene glycol-block-poly (D,L-lactide) micelles for efficient cancer therapy

Authors: Chang Zu, Yinglan Yu, Caiwei Yu, Yi Li, Runing Sun, Birendra Chaurasiya, Baoqiang Tang, Daquan Chen, Jiasheng Tu, Yan Shen

Source: Drug Delivery, Vol 27, Iss 1, Pp 248-257 (2020)

Subject Terms: deoxypodophyllotoxin, mpeg-pdlla, polymeric micelles, lyophilization, anti-tumor, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1071-7544; https://doaj.org/toc/1521-0464

Access URL: https://doaj.org/article/638e79e1f11b486d88cc8199993043c2

Novel nano-pomegranates based on astragalus polysaccharides for targeting ERα-positive breast cancer and multidrug resistance

Authors: Bingjie Wang, Chunjing Guo, Yanhui Liu, Guangting Han, Yi Li, Yanchun Zhang, Haiyu Xu, Daquan Chen

Source: Drug Delivery, Vol 27, Iss 1, Pp 607-621 (2020)

Subject Terms: astragalus polysaccharides, targeting erα-positive breast cancer, multidrug resistance, nano-pomegranates, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/1071-7544; https://doaj.org/toc/1521-0464

Access URL: https://doaj.org/article/3abc427266784aec92431a9fca4141ed

Broad-specific monoclonal antibody based IACs purification coupled UPLC-MS/MS method for T-2 and HT-2 toxin determination in maize and cherry samples

Authors: Yanshen Li, Shaoxia Lin, Yunhui Wang, Xin Mao, Yongning Wu, Yunguo Liu, Daquan Chen

Source: Food and Agricultural Immunology, Vol 31, Iss 1, Pp 291-302 (2020)

Subject Terms: broad-specific immune-affinity columns, t-2 toxin, ht-2 toxin, uplc-ms/ms, Agriculture (General), S1-972, Immunologic diseases. Allergy, RC581-607

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Relation: https://doaj.org/toc/0954-0105; https://doaj.org/toc/1465-3443

Access URL: https://doaj.org/article/a88fd56f396a44949b78819f1d280192

Synthesis, Characterization, and Evaluation of Redox-Sensitive Chitosan Oligosaccharide Nanoparticles Coated with Phycocyanin for Drug Delivery

Authors: Ziting Cheng, Wei Zhang, Xiaoya Hou, Bingjie Wang, Yanping Zhu, Peng Zhang, Feng Zhao, Daquan Chen

Source: Nanoscale Research Letters, Vol 14, Iss 1, Pp 1-11 (2019)

Subject Terms: Phycocyanin, Biotin, Chitosan oligosaccharide, Nanoparticles, A549 cells, Drug delivery, Materials of engineering and construction. Mechanics of materials, TA401-492

File Description: electronic resource

Relation: https://doaj.org/toc/1931-7573; https://doaj.org/toc/1556-276X

Access URL: https://doaj.org/article/82c6e129a8a04a8ba680bef74fae9734

Protoporphyrin IX-loaded laminarin nanoparticles for anticancer treatment, their cellular behavior, ROS detection, and animal studies

Authors: Yueming Yu, Bingjie Wang, Chunjing Guo, Feng Zhao, Daquan Chen

Source: Nanoscale Research Letters, Vol 14, Iss 1, Pp 1-12 (2019)

Subject Terms: Laminarin, PDT, Pp IX, Anti-tumor, Nanomedicine, MCF-7 cells, Materials of engineering and construction. Mechanics of materials, TA401-492

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s11671-019-3138-0; https://doaj.org/toc/1931-7573; https://doaj.org/toc/1556-276X

Access URL: https://doaj.org/article/2b7699f4085f4048ac85169ba0b79b40

Pharmacological Effects of Polyphenol Phytochemicals on the JAK-STAT Signaling Pathway

Authors: Qianqian Yin, Longyun Wang, Haiyang Yu, Daquan Chen, Wenwei Zhu, Changgang Sun

Source: Frontiers in Pharmacology, Vol 12 (2021)

Subject Terms: JAK, STAT, signaling pathway, polyphenols, phytochemicals, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.716672/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/e1ced3d877c9491480618dec66043d37