Multifaceted impact of HIV inhibitor dapivirine on triple negative breast cancer cells reveals potential entities as targets for novel therapy

Authors: Ketki Patil, Elizabeth Johnston, Joseph Novack, Garrett Wallace, Michelle Lin, S. Balakrishna Pai

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)

Subject Terms: Triple negative breast cancer, Dapivirine, MDA-MB-231, Apoptosis, Proteomics, Multicaspase, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/f1a5a0fb143140758569c5ebd2d3ee66

Corrigendum: Oral pre-exposure prophylaxis implementation in South Africa: a case study of USAID-supported programs

Authors: Jerome Wendoh Milimu, Lauren Parmley, Mahlodi Matjeng, Mathata Madibane, Mandisi Mabika, Jacques Livingston, Joseph Lawrence, Orapeleng Motlhaoleng, Hasina Subedar, Rethabile Tsekoa, Zandile Mthembu

Source: Frontiers in Reproductive Health, Vol 7 (2025)

Subject Terms: HIV prevention, pre-exposure prophylaxis, PEPFAR program, South Africa, cabotegravir, dapivirine ring, Reproduction, QH471-489, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/frph.2025.1561341/full; https://doaj.org/toc/2673-3153

Access URL: https://doaj.org/article/0f550f8babbc4df891acb0546b559172

Oral pre-exposure prophylaxis implementation in South Africa: a case study of USAID-supported programs

Authors: Jerome Wendoh Milimu, Lauren Parmley, Mahlodi Matjeng, Mathata Madibane, Mandisi Mabika, Jacques Livingston, Joseph Lawrence, Orapeleng Motlhaoleng, Hasina Subedar, Rethabile Tsekoa, Zandile Mthembu

Source: Frontiers in Reproductive Health, Vol 6 (2024)

Subject Terms: HIV prevention, pre-exposure prophylaxis, PEPFAR program, South Africa, cabotegravir, dapivirine ring, Reproduction, QH471-489, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/frph.2024.1473354/full; https://doaj.org/toc/2673-3153

Access URL: https://doaj.org/article/ae1e95fa7c254f1fab4ac4d0b64a2740

Self-reported removal and expulsion of the dapivirine vaginal ring: qualitative reports from female ring users and their male partners in the Ring Study (IPM 027)

Authors: Cecilia Milford, Hariska Ramlal, Rorisang Mofokeng, Letitia Rambally Greener, Annaléne Nel, Jennifer Smit, Mariëtte Malherbe

Source: BMC Public Health, Vol 24, Iss 1, Pp 1-12 (2024)

Subject Terms: HIV prevention, Vaginal ring, Male partners, Dapivirine, Adherence, Sub-Saharan Africa, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2458

Access URL: https://doaj.org/article/e2948942c16b4b1bab81201aa09075cf

Efficient regulatory approval of two novel HIV prevention interventions in a resource-limited setting: experiences from Zimbabwe

Authors: Caroline Murombedzi, Libert Chirinda, Gift T. Chareka, Z. Mike Chirenje, Nyaradzo M. Mgodi

Source: Frontiers in Reproductive Health, Vol 5 (2023)

Subject Terms: HIV, pre-exposure prophylaxis, dapivirine vaginal ring, long-acting injectable cabotegravir, regulatory approval, Zimbabwe, Reproduction, QH471-489, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/frph.2023.1279124/full; https://doaj.org/toc/2673-3153

Access URL: https://doaj.org/article/798550697c1f445dbcd671f1917a996b

Planning for decentralized, simplified prEP: Learnings from potential end users in Ga-Rankuwa, gauteng, South Africa

Authors: Paballo Mataboge, Susan Nzenze, Nqaba Mthimkhulu, Mbali Mazibuko, Alison Kutywayo, Vusile Butler, Nicolette Naidoo, Saiqa Mullick

Source: Frontiers in Reproductive Health, Vol 4 (2023)

Subject Terms: hiv prevention, dapivirine vaginal ring, long-acting cabotegravir, decentralized, simplified service delivery, Reproduction, QH471-489, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/frph.2022.1081049/full; https://doaj.org/toc/2673-3153

Access URL: https://doaj.org/article/da2022cc05714b1fa863c6a9189d4f43

Impact and experience of participant engagement activities in supporting dapivirine ring use among participants enrolled in the phase III MTN-020/ASPIRE study

Authors: Morgan Garcia, Ellen Luecke, Ashley J. Mayo, Rachel Scheckter, Patrick Ndase, Flavia Matovu Kiweewa, Doreen Kemigisha, Petina Musara, Leila E. Mansoor, Nishanta Singh, Kubashni Woeber, Neetha S. Morar, Nitesha Jeenarain, Zakir Gaffoor, Daniel K. Gondwe, Yvonne Makala, Llewellyn Fleurs, Krishnaveni Reddy, Thesla Palanee-Phillips, Jared M. Baeten, Ariane van der Straten, Lydia Soto-Torres, Kristine Torjesen

Source: BMC Public Health, Vol 21, Iss 1, Pp 1-11 (2021)

Subject Terms: Adherence, Participant engagement, Microbicides, Ring, Dapivirine, PrEP, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2458

Access URL: https://doaj.org/article/c42e11a6e8a640d9b0d026c07dfa4e70

Use of simulated vaginal and menstrual fluids to model in vivo discolouration of silicone elastomer vaginal rings

Authors: Clare F. McCoy, Patrick Spence, Yahya H. Dallal Bashi, Diarmaid J. Murphy, Peter Boyd, Bindi Dangi, Tiffany Derrick, Bríd Devlin, Kyle Kleinbeck, R. Karl Malcolm

Source: International Journal of Pharmaceutics: X, Vol 3, Iss , Pp 100081- (2021)

Subject Terms: HIV microbicide, Antiretroviral, Dapivirine, Levonorgestrel, Hormonal contraception, Multipurpose prevention technology, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590156721000104; https://doaj.org/toc/2590-1567

Access URL: https://doaj.org/article/33201504c4cc4078bdec85999ffab7fe

Comprehensive Study of Antiretroviral Drug Permeability at the Cervicovaginal Mucosa via an In Vitro Model

Authors: Constandinos Carserides, Kieron Smith, Marta Zinicola, Abhinav Kumar, Magda Swedrowska, Carlo Scala, Gary Cameron, Zoe Riches, Francesco Iannelli, Gianni Pozzi, Georgina L. Hold, Ben Forbes, Charles Kelly, Karolin Hijazi

Source: Pharmaceutics, Vol 14, Iss 9, p 1938 (2022)

Subject Terms: HIV-1, female genital tract, darunavir, tenofovir, dapivirine, drug permeability, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/14/9/1938; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/ddf5f56e7556446f8f22c858e7c7072e

Transport and Permeation Properties of Dapivirine: Understanding Potential Drug-Drug Interactions

Authors: Ruohui Zheng, Guru R. Valicherla, Junmei Zhang, Jeremy Nuttall, Peter Silvera, Leslie J. Marshall, Philip E. Empey, Lisa C. Rohan

Source: Pharmaceutics, Vol 14, Iss 9, p 1948 (2022)

Subject Terms: dapivirine, drug transporters, tissue permeability, drug-drug interactions, HIV, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/14/9/1948; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/e4fb5b9b7a494d1bbd074a70a13b599f

Investigating the Contribution of Drug-Metabolizing Enzymes in Drug-Drug Interactions of Dapivirine and Miconazole

Authors: Guru Raghavendra Valicherla, Phillip Graebing, Junmei Zhang, Ruohui Zheng, Jeremy Nuttall, Peter Silvera, Lisa Cencia Rohan

Source: Pharmaceutics, Vol 13, Iss 12, p 2193 (2021)

Subject Terms: dapivirine, drug-drug interactions, HIV, drug metabolizing enzymes, miconazole, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/13/12/2193; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/14351c89998d4564b556c9d08978d8c7

Mucoadhesive Vaginal Discs based on Cyclodextrin and Surfactants for the Controlled Release of Antiretroviral Drugs to Prevent the Sexual Transmission of HIV

Authors: Fernando Notario-Pérez, Araceli Martín-Illana, Raúl Cazorla-Luna, Roberto Ruiz-Caro, Aitana Tamayo, Juan Rubio, Veiga María-Dolores

Source: Pharmaceutics, Vol 12, Iss 4, p 321 (2020)

Subject Terms: coitally-dependent microbicide, dapivirine, freeze-dried gels, human immunodeficiency virus, 2-hydroxypropyl-β-cyclodextrin, mucoadhesive vaginal discs, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/12/4/321; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/dbda47b28648479287b5bdbc54a31d33

Review The Emerging Profile of Cross-Resistance among the Nonnucleoside HIV-1 Reverse Transcriptase Inhibitors

Authors: Nicolas Sluis-Cremer

Source: Viruses, Vol 6, Iss 8, Pp 2960-2973 (2014)

Subject Terms: HIV, reverse transcriptase, nonnucleoside inhibitors, nevirapine, efavirenz, rilpivirine, etravirine, dapivirine, MIV-150, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.mdpi.com/1999-4915/6/8/2960; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/294a66db67b5403b8ab48bc7a1ea5686

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