Characterizing the Genomic Landscape of the Micropapillary Subtype of Urothelial Carcinoma of the Bladder Harboring Activating Extracellular Mutations of ERBB2

Authors: Posada, Jessica M. ^{a, b}, Yakirevich, Evgeny ^a, Kamat, Ashish M. ^c, Sood, Akshay ^d, Jacob, Joseph M. ^e, Bratslavsky, Gennady ^e, Grivas, Petros ^f, Spiess, Philippe E. ^g, Li, Roger ^g, Necchi, Andrea ^h, Mega, Anthony E. ⁱ, Golijanin, Dragan J. ^j, Pavlick, Dean ^k, Huang, Richard S.P. ^k, Lin, Douglas ^k, Danziger, Natalie ^k, Sokol, Ethan S. ^k, Sivakumar, Smruthy ^k, Ross, Jeffrey S. ^{e, k, ∗}, Cheng, Liang ^{a, ∗}

Source: In Modern Pathology March 2024 37(3)

Genomic landscape of non‐small‐cell lung cancer with methylthioadenosine phosphorylase (MTAP) deficiency

Authors: Ashok Kumar, Prashanth, Graziano, Stephen L., Danziger, Natalie, Pavlick, Dean, Severson, Eric A., Ramkissoon, Shakti H., Huang, Richard S. P., Decker, Brennan, Ross, Jeffrey S.

Source: Cancer medicine. 12(2):1157-1166

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172902788.0x000001&indx=1&recIds=ETOCvdc_100172902788.0x000001

Mismatch repair deficiency, next-generation sequencing-based microsatellite instability, and tumor mutational burden as predictive biomarkers for immune checkpoint inhibitor effectiveness in frontline treatment of advanced stage endometrial cancer

Authors: Hill, Breana L ^{1, *}, Graf, Ryon P ², Shah, Kunal ³, Danziger, Natalie ⁴, Lin, Douglas I ⁴, Quintanilha, Julia ⁵, Li, Gerald ⁵, Haberberger, James ⁶, Ross, Jeffrey S ⁴, Santin, Alessandro D ⁷, Slomovitz, Brian ⁸, Elvin, Julia A ⁴, Eskander, Ramez N ¹

Source: In International Journal of Gynecological Cancer April 2023 33(4):504-513

Molecular analysis of endometrial serous carcinoma reveals distinct clinicopathologic and genomic subgroups

Authors: Lin, Douglas I., Fine, Alexander, Danziger, Natalie A., Huang, Richard S.P., Mata, Douglas A., Decker, Brennan, Killian, Jonathan K., Ramkissoon, Shakti H., Lechpammer, Mirna, Janovitz, Tyler, Ross, Jeffrey S., Sokol, Ethan S., Elvin, Julia A.

Source: Gynecologic oncology. 164(3):558-565

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100168719294.0x000001&indx=1&recIds=ETOCvdc_100168719294.0x000001

Clinicopathological and genomic characterization of BCORL1-driven high-grade endometrial stromal sarcomas

Authors: Lin, Douglas I., Huang, Richard S.P., Mata, Douglas A., Decker, Brennan, Danziger, Natalie, Lechpammer, Mirna, Hiemenz, Matthew, Ramkissoon, Shakti H., Ross, Jeffrey S., Elvin, Julia A.

Source: In Modern Pathology December 2021 34(12):2200-2210

Clinicopathologic and genomic characterization of PD-L1-positive uterine cervical carcinoma

Authors: Huang, Richard S.P., Haberberger, James, Murugesan, Karthikeyan, Danziger, Natalie, Hiemenz, Matthew, Severson, Eric, Duncan, Daniel L., Ramkissoon, Shakti H., Ross, Jeffrey S., Elvin, Julia A., Lin, Douglas I.

Source: In Modern Pathology July 2021 34(7):1425-1433

Correlating ROS1 Protein Expression With ROS1 Fusions, Amplifications, and Mutations

Authors: Huang, Richard S.P., Gottberg-Williams, Amanda, Vang, Panhia, Yang, Shoua, Britt, Nicholas, Kaur, Jaspreet, Haberberger, James, Danziger, Natalie, Owens, Clarence, Beckloff, Sara E., Ross, Jeffrey S., Ramkissoon, Shakti H.

Source: In JTO Clinical and Research Reports February 2021 2(2)

A pan-cancer analysis of PD-L1 immunohistochemistry and gene amplification, tumor mutation burden and microsatellite instability in 48,782 cases

Authors: Huang, Richard S.P., Haberberger, James, Severson, Eric, Duncan, Daniel L., Hemmerich, Amanda, Edgerly, Claire, Ferguson, Naomi Lynn, Williams, Erik, Elvin, Julia, Vergilio, Jo-Anne, Killian, Jonathan Keith, Lin, Douglas I., Tse, Julie, Hiemenz, Matthew, Owens, Clarence, Danziger, Natalie, Hegde, Priti S., Venstrom, Jeffrey, Alexander, Brian, Ross, Jeffrey S., Ramkissoon, Shakti H.

Source: In Modern Pathology February 2021 34(2):252-263

Clinicopathologic and Genomic Landscape of Breast Carcinoma Brain Metastases

Authors: Huang, Richard S.P., Haberberger, James, McGregor, Kimberly, Mata, Douglas A., Decker, Brennan, Hiemenz, Matthew C., Lechpammer, Mirna, Danziger, Natalie, Schiavone, Kelsie, Creeden, James, Graf, Ryon P., Strowd, Roy, Lesser, Glenn J., Razis, Evangelia D., Bartsch, Rupert, Giannoudis, Athina, Bhogal, Talvinder, Lin, Nancy U., Pusztai, Lajos, Ross, Jeffrey S., Palmieri, Carlo, Ramkissoon, Shakti H.

Source: Oncologist. 26(10):835-844

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131000578.0x000001&indx=1&recIds=ETOCvdc_100131000578.0x000001

Comparative Genomic Analysis of Intrahepatic Cholangiocarcinoma: Biopsy Type, Ancestry, and Testing Patterns

Authors: Israel, Mason A., Danziger, Natalie, McGregor, Kimberly A., Murugesan, Karthikeyan, Gjoerup, Ole, Sokol, Ethan S., Tukachinsky, Hanna, Kurzrock, Razelle, Kato, Shumei, Sicklick, Jason K., Nimeiri, Halla S., Oxnard, Geoffrey R., Ross, Jeffrey S.

Source: Oncologist. 26(9):787-796

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100129260777.0x000001&indx=1&recIds=ETOCvdc_100129260777.0x000001

Clinicopathologic, genomic and protein expression characterization of 356 ROS1 fusion driven solid tumors cases

Authors: Huang, Richard S. P., Haberberger, James, Sokol, Ethan, Schrock, Alexa B., Danziger, Natalie, Madison, Russell, Trabucco, Sally, Jin, Dexter, Pavlick, Dean, Ramanan, Vivek, Hole, Kanchan, McGregor, Kimberly, Venstrom, Jeffrey, Ross, Jeffrey S.

Source: International journal of cancer. 148(7):1778-1788

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100116948926.0x000001&indx=1&recIds=ETOCvdc_100116948926.0x000001

Contrasting genomic profiles from metastatic sites, primary tumors, and liquid biopsies of advanced prostate cancer

Authors: Necchi, Andrea, Cucchiara, Vito, Grivas, Petros, Bratslavsky, Gennady, Jacob, Joseph, Spiess, Philippe E., Sokol, Ethan S., Killian, Jonathan Keith, Lin, Douglas, Ramkissoon, Shakti, Huang, Richard S. P., Madison, Russell W., Venstrom, Jeffrey M., Schrock, Alexa B., Danziger, Natalie, Decker, Brennan, Gjoerup, Ole, Graf, Ryon P., Oxnard, Geoffrey R., Tukachinsky, Hanna, Ross, Jeffrey S.

Source: Cancer. 127(24):4557-4564

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157759760.0x000001&indx=1&recIds=ETOCvdc_100157759760.0x000001

Comprehensive Immunogenomic Profiling of IDH1- / 2 -Altered Cholangiocarcinoma.

Authors: Makawita, Shalini, Lee, Sunyoung, Kong, Elisabeth, Kwong, Lawrence N., Abouelfetouh, Zeyad, Danner De Armas, Anaemy, Xiao, Lianchun, Murugesan, Karthikeyan, Danziger, Natalie, Pavlick, Dean, Korkut, Anil, Ross, Jeffrey S., Javle, Milind

Source: JCO Precision Oncology; 12/1/2024, Vol. 8, p1-14, 14p

Subject Terms: KILLER cells, BIOMARKERS, HOMOLOGOUS recombination, GENE expression, APOPTOSIS

Genomic landscape of malignant phyllodes tumors reveals multiple targetable opportunities.

Authors: Rosenberger, Laura H, Riedel, Richard F, Diego, Emilia J, Nash, Amanda L, Grilley-Olson, Juneko E, Danziger, Natalie A, Sokol, Ethan S, Ross, Jeffrey S, Sammons, Sarah L

Source: Oncologist; Dec2024, Vol. 29 Issue 12, p1024-1031, 8p

Subject Terms: BREAST tumors, IMMUNOTHERAPY, FISHER exact test, TUMOR markers, CANCER patients, DESCRIPTIVE statistics, GENE expression profiling, GENETIC mutation, CASE studies

Single-Hit and Multi-hit PIK3CA Short Variant Genomic Alterations in Clinically Advanced Prostate Cancer: A Genomic Landscape Study.

Authors: Basin, Michael F., Miguel, Carla M., Jacob, Joseph M., Goldberg, Hanan, Grivas, Petros, Spiess, Philippe E., Necchi, Andrea, Kamat, Ashish M., Pavlick, Dean C., Huang, Richard S. P., Lin, Douglas I., Danziger, Natalie, Sokol, Ethan S., Sivakumar, Smruthy, Graf, Ryon, Cheng, Liang, Vasan, Neil, Ross, Jeffrey, Basnet, Alina, Bratslavsky, Gennady

Source: Targeted Oncology; Nov2024, Vol. 19 Issue 6, p981-990, 10p

776 POLE-Ultramutated Prostatic Carcinoma: a Rare Molecularly Defined Prostate Cancer Subtype With Potential for Durable Response to Immunotherapy

Authors: Byrne, Chloe ¹, Danziger, Natalie ², Ross, Jeffrey ³, Elvin, Julia ¹, Decker, Brennan ², Mata, Douglas ², Ye, Huihui ⁴, Cheng, Liang ⁵, Lin, Douglas ¹

Source: In Laboratory Investigation March 2025 105(3) Supplement

Biomarkers in Breast Cancer: An Integrated Analysis of Comprehensive Genomic Profiling and PD‐L1 Immunohistochemistry Biomarkers in 312 Patients with Breast Cancer

Authors: Huang, Richard S.P., Li, Xinyan, Haberberger, James, Sokol, Ethan, Severson, Eric, Duncan, Daniel L., Hemmerich, Amanda, Edgerly, Claire, Williams, Erik, Elvin, Julia, Vergilio, Jo‐Anne, Killian, Jonathan Keith, Lin, Douglas, Hiemenz, Matthew, Xiao, Jinpeng, McEwan, Deborah, Holmes, Oliver, Danziger, Natalie, Erlich, Rachel, Frampton, Garrett, Cohen, Michael B., McGregor, Kimberly, Reddy, Prasanth, Cardeiro, Dawn, Anhorn, Rachel, Venstrom, Jeffrey, Alexander, Brian, Brown, Charlotte, Pusztai, Lajos, Ross, Jeffrey S., Ramkissoon, Shakti H.

Source: Oncologist. 25(11):943-953

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100109216678.0x000001&indx=1&recIds=ETOCvdc_100109216678.0x000001

Pan-tumor validation of a NGS fraction-based MSI analysis as a predictor of response to Pembrolizumab.

Authors: Lin, Douglas I., Quintanilha, Julia C. F., Danziger, Natalie, Lang, Lixin, Levitan, Diane, Hayne, Cynthia, Hiemenz, Matthew C., Smith, David L., Albacker, Lee A., Leibowitz, Jeffrey, Mata, Douglas A., Decker, Brennan, Lakis, Sotirios, Patel, Nimesh R., Graf, Ryon P., Elvin, Julia A., Ross, Jeffrey S., Pattani, Varun, Huang, Richard S. P., Wehn, Amy K.

Source: NPJ Precision Oncology; 9/14/2024, Vol. 8 Issue 1, p1-9, 9p

Subject Terms: TREATMENT effectiveness, NUCLEOTIDE sequencing, TUMOR treatment, DATABASES, MICROSATELLITE repeats

Genomic profiling and comparative analysis of male versus female metastatic breast cancer across subtypes.

Authors: Kadamkulam Syriac, Arun, Nandu, Nitish Singh, Clark, Allison, Tavallai, Mehrad, Jin, Dexter X., Sokol, Ethan, McGregor, Kimberly, Ross, Jeffrey S., Danziger, Natalie, Leone, Jose Pablo

Source: Breast Cancer Research; 7/24/2024, Vol. 26 Issue 1, p1-10, 10p

Subject Terms: METASTATIC breast cancer, MALE breast cancer, EPIDERMAL growth factor receptors, CANCER genes, ESTROGEN receptors

Clinical, histopathologic, and molecular profiles of PRKAR1A-inactivated melanocytic neoplasms

Authors: Williams, Erik A., Shah, Nikunj, Danziger, Natalie, Montesion, Meagan, Sokol, Ethan S., Pavlick, Dean C., Miller, Vincent A., Ross, Jeffrey S., Elvin, Julia A., Tse, Julie Y.

Source: Journal of the American Academy of Dermatology. 84(4):1069-1071

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100182480682.0x000001&indx=1&recIds=ETOCvdc_100182480682.0x000001