Gain and loss of function variants in EZH1 disrupt neurogenesis and cause dominant and recessive neurodevelopmental disorders

Authors: Carolina Gracia-Diaz, Yijing Zhou, Qian Yang, Reza Maroofian, Paula Espana-Bonilla, Chul-Hwan Lee, Shuo Zhang, Natàlia Padilla, Raquel Fueyo, Elisa A. Waxman, Sunyimeng Lei, Garrett Otrimski, Dong Li, Sarah E. Sheppard, Paul Mark, Margaret H. Harr, Hakon Hakonarson, Lance Rodan, Adam Jackson, Pradeep Vasudevan, Corrina Powel, Shehla Mohammed, Sateesh Maddirevula, Hamad Alzaidan, Eissa A. Faqeih, Stephanie Efthymiou, Valentina Turchetti, Fatima Rahman, Shazia Maqbool, Vincenzo Salpietro, Shahnaz H. Ibrahim, Gabriella di Rosa, Henry Houlden, Maha Nasser Alharbi, Nouriya Abbas Al-Sannaa, Peter Bauer, Giovanni Zifarelli, Conchi Estaras, Anna C. E. Hurst, Michelle L. Thompson, Anna Chassevent, Constance L. Smith-Hicks, Xavier de la Cruz, Alexander M. Holtz, Houda Zghal Elloumi, M J Hajianpour, Claudine Rieubland, Dominique Braun, Siddharth Banka, Genomic England Research Consortium, Deborah L. French, Elizabeth A. Heller, Murielle Saade, Hongjun Song, Guo-li Ming, Fowzan S. Alkuraya, Pankaj B. Agrawal, Danny Reinberg, Elizabeth J. Bhoj, Marian A. Martínez-Balbás, Naiara Akizu

Source: Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/78105606e072432f9749da08dbbd20b7

Structures of monomeric and dimeric PRC2:EZH1 reveal flexible modules involved in chromatin compaction

Authors: Daniel Grau, Yixiao Zhang, Chul-Hwan Lee, Marco Valencia-Sánchez, Jenny Zhang, Miao Wang, Marlene Holder, Vladimir Svetlov, Dongyan Tan, Evgeny Nudler, Danny Reinberg, Thomas Walz, Karim-Jean Armache

Source: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ed6bec3062f3495c95ba56cf7a4fc536

Low-Grade Astrocytoma Mutations in IDH1, P53, and ATRX Cooperate to Block Differentiation of Human Neural Stem Cells via Repression of SOX2

Authors: Aram S. Modrek, Danielle Golub, Themasap Khan, Devin Bready, Jod Prado, Christopher Bowman, Jingjing Deng, Guoan Zhang, Pedro P. Rocha, Ramya Raviram, Charalampos Lazaris, James M. Stafford, Gary LeRoy, Michael Kader, Joravar Dhaliwal, N. Sumru Bayin, Joshua D. Frenster, Jonathan Serrano, Luis Chiriboga, Rabaa Baitalmal, Gouri Nanjangud, Andrew S. Chi, John G. Golfinos, Jing Wang, Matthias A. Karajannis, Richard A. Bonneau, Danny Reinberg, Aristotelis Tsirigos, David Zagzag, Matija Snuderl, Jane A. Skok, Thomas A. Neubert, Dimitris G. Placantonakis

Source: Cell Reports, Vol 21, Iss 5, Pp 1267-1280 (2017)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124717314262; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/6c38719ab387499d9cbeaef12ccef89b

Specialized odorant receptors in social insects that detect cuticular hydrocarbon cues and candidate pheromones

Authors: Gregory M. Pask, Jesse D. Slone, Jocelyn G. Millar, Prithwiraj Das, Jardel A. Moreira, Xiaofan Zhou, Jan Bello, Shelley L. Berger, Roberto Bonasio, Claude Desplan, Danny Reinberg, Jürgen Liebig, Laurence J. Zwiebel, Anandasankar Ray

Source: Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/cda7bbb821e143f7b50ef1864ea66992

Chemosensory sensitivity reflects reproductive status in the ant Harpegnathos saltator

Authors: Majid Ghaninia, Kevin Haight, Shelley L. Berger, Danny Reinberg, Laurence J. Zwiebel, Anandasankar Ray, Jürgen Liebig

Source: Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/d33dc11fd9da4f26adf49f793f1f5caa

Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2

Authors: Neil Justin, Ying Zhang, Cataldo Tarricone, Stephen R. Martin, Shuyang Chen, Elizabeth Underwood, Valeria De Marco, Lesley F. Haire, Philip A. Walker, Danny Reinberg, Jon R. Wilson, Steven J. Gamblin

Source: Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/7ab848514085441b822b8a2f77f90739

Cuticular Hydrocarbon Pheromones for Social Behavior and Their Coding in the Ant Antenna

Authors: Kavita R. Sharma, Brittany L. Enzmann, Yvonne Schmidt, Dani Moore, Graeme R. Jones, Jane Parker, Shelley L. Berger, Danny Reinberg, Laurence J. Zwiebel, Bernhard Breit, Jürgen Liebig, Anandasankar Ray

Source: Cell Reports, Vol 12, Iss 8, Pp 1261-1271 (2015)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124715007913; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/4a0c6c4f2d8f4b989c123db3cfce5dae

Interactions with RNA direct the Polycomb group protein SCML2 to chromatin where it represses target genes

Authors: Roberto Bonasio, Emilio Lecona, Varun Narendra, Philipp Voigt, Fabio Parisi, Yuval Kluger, Danny Reinberg

Source: eLife, Vol 3 (2014)

Subject Terms: Polycomb, noncoding RNA, chromatin, SCML2, PRC1, MBT, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/02637; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/ed5f2b287b9d434a9af7a1beb74f7b6f

Polycomb protein SCML2 regulates the cell cycle by binding and modulating CDK/CYCLIN/p21 complexes.

Authors: Emilio Lecona, Luis Alejandro Rojas, Roberto Bonasio, Andrew Johnston, Oscar Fernández-Capetillo, Danny Reinberg

Source: PLoS Biology, Vol 11, Iss 12, p e1001737 (2013)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24358021/?tool=EBI; https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/d4ddbaaa48fc4b02b8abd870469d19f8

Deregulated FGF and homeotic gene expression underlies cerebellar vermis hypoplasia in CHARGE syndrome

Authors: Tian Yu, Linda C Meiners, Katrin Danielsen, Monica TY Wong, Timothy Bowler, Danny Reinberg, Peter J Scambler, Conny MA van Ravenswaaij-Arts, M Albert Basson

Source: eLife, Vol 2 (2013)

Subject Terms: cerebellum, CHARGE syndrome, CHD7, FGF8, OTX2, GBX2, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/01305; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/177ff238e4a449628e696d4302b16ad9

Phylogenetic and transcriptomic analysis of chemosensory receptors in a pair of divergent ant species reveals sex-specific signatures of odor coding.

Authors: Xiaofan Zhou, Jesse D Slone, Antonis Rokas, Shelley L Berger, Jürgen Liebig, Anandasankar Ray, Danny Reinberg, Laurence J Zwiebel

Source: PLoS Genetics, Vol 8, Iss 8, p e1002930 (2012)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002930&type=printable; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/9b1847b600714b91b14e7355fde9cdd5

Crystal structure of TDRD3 and methyl-arginine binding characterization of TDRD3, SMN and SPF30.

Authors: Ke Liu, Yahong Guo, Haiping Liu, Chuanbing Bian, Robert Lam, Yongsong Liu, Farrell Mackenzie, Luis Alejandro Rojas, Danny Reinberg, Mark T Bedford, Rui-Ming Xu, Jinrong Min

Source: PLoS ONE, Vol 7, Iss 2, p e30375 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3281842?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/6fccd819d46f45daa02ee5d99a6f918f

Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins

Authors: Patrick Trojer (New York University School of Medicine), Jin Zhang (New York University School of Medicine), Masato Yonezawa (IMP - Research Institute of Molecular Pathology), Andreas Schmidt (Department of Biochemistry and Cell Biology, Centre for Molecular Biology, University of Vienna), Haiyan Zheng (University of Medicine & Dentistry of New Jersey), Thomas Jenuwein (Vienna Biocenter), Danny Reinberg (New York University School of Medicine)

Availability: http://data.europeana.eu/aggregation/europeana/1300/https___phaidra_univie_ac_at_o_243826

A Method to Study de novo Formation of Chromatin Domains

Authors: Ozgur Oksuz, author^{1, 2, 3}, Danny Reinberg, author^{1, 2}

Source: Journal of Visualized Experiments. (150)

Availability: http://www.jove.com/video/60039

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Transcriptional Activation: Tuning-up transcription

Authors: Sheldon, Michael, Danny, Reinberg

Source: In Current Biology January 1995 5(1):43-46