The L-Arginine Transporter Solute Carrier Family 7 Member 2 Mediates the Immunopathogenesis of Attaching and Effacing Bacteria.

Authors: Kshipra Singh, Nicole T Al-Greene, Thomas G Verriere, Lori A Coburn, Mohammad Asim, Daniel P Barry, Margaret M Allaman, Dana M Hardbower, Alberto G Delgado, M Blanca Piazuelo, Bruce A Vallance, Alain P Gobert, Keith T Wilson

Source: PLoS Pathogens, Vol 12, Iss 10, p e1005984 (2016)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5081186?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/dde25832be474145b30f534c31096627

L-arginine supplementation improves responses to injury and inflammation in dextran sulfate sodium colitis.

Authors: Lori A Coburn, Xue Gong, Kshipra Singh, Mohammad Asim, Brooks P Scull, Margaret M Allaman, Christopher S Williams, Michael J Rosen, M Kay Washington, Daniel P Barry, M Blanca Piazuelo, Robert A Casero, Rupesh Chaturvedi, Zhongming Zhao, Keith T Wilson

Source: PLoS ONE, Vol 7, Iss 3, p e33546 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3299802?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/533feca6ab3b4bd2a33c8baf8209e8b6

Difluoromethylornithine is a novel inhibitor of Helicobacter pylori growth, CagA translocation, and interleukin-8 induction.

Authors: Daniel P Barry, Mohammad Asim, David A Leiman, Thibaut de Sablet, Kshipra Singh, Robert A Casero, Rupesh Chaturvedi, Keith T Wilson

Source: PLoS ONE, Vol 6, Iss 2, p e17510 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3046249?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/caf3d875014246a289923380d70287b6

Cationic amino acid transporter 2 enhances innate immunity during Helicobacter pylori infection.

Authors: Daniel P Barry, Mohammad Asim, Brooks P Scull, M Blanca Piazuelo, Thibaut de Sablet, Nuruddeen D Lewis, Lori A Coburn, Kshipra Singh, Lesley G Ellies, Alain P Gobert, Rupesh Chaturvedi, Keith T Wilson

Source: PLoS ONE, Vol 6, Iss 12, p e29046 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3237590?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/09ba87fccc7840d89038169ee39687b0

Analysis of the effect of hypusination in myeloid cells on colitis and colitis-associated cancer

Authors: Alain P. Gobert, Jordan Finley, Mohammad Asim, Daniel P. Barry, Margaret M. Allaman, Caroline V. Hawkins, Kamery J. Williams, Alberto G. Delagado, Raghavendra G. Mirmira, Shilin Zhao, M. Blanca Piazuelo, M. Kay Washington, Lori A. Coburn, Keith T. Wilson

Source: Heliyon, Vol 10, Iss 13, Pp e33838- (2024)

Subject Terms: Inflammatory bowel diseases, Inflammation, Hypusine, Colon, Colorectal cancer, Gut microbiota, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024098694; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/02fd8b1c2fd24f64a472e36bac86f199

Myeloid deletion of talin-1 reduces mucosal macrophages and protects mice from colonic inflammation

Authors: Yvonne L. Latour, Kara M. McNamara, Margaret M. Allaman, Daniel P. Barry, Thaddeus M. Smith, Mohammad Asim, Kamery J. Williams, Caroline V. Hawkins, Justin Jacobse, Jeremy A. Goettel, Alberto G. Delgado, M. Blanca Piazuelo, M. Kay Washington, Alain P. Gobert, Keith T. Wilson

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/fb0bf8276c3646598c802c501115e29e

Epithelial talin-1 protects mice from Citrobacter rodentium-induced colitis by restricting bacterial crypt intrusion and enhancing T cell immunity

Authors: Yvonne L. Latour, Margaret M. Allaman, Daniel P. Barry, Thaddeus M. Smith, Kamery J. Williams, Kara M. McNamara, Justin Jacobse, Jeremy A. Goettel, Alberto G. Delgado, M. Blanca Piazuelo, Shilin Zhao, Alain P. Gobert, Keith T. Wilson

Source: Gut Microbes, Vol 15, Iss 1 (2023)

Subject Terms: Talin, C. rodentium, colonic epithelial cells, neutrophils, T cells, colon organoids, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/f9ea48e1d73a40c2ba5b50cc0608468a

The reverse transsulfuration pathway affects the colonic microbiota and contributes to colitis in mice

Authors: Alain P. Gobert, Yvonne L. Latour, Kara M. McNamara, Caroline V. Hawkins, Kamery J. Williams, Mohammad Asim, Daniel P. Barry, Margaret M. Allaman, Alberto G. Delgado, Ginger L. Milne, Shilin Zhao, M. Blanca Piazuelo, M. Kay Washington, Lori A. Coburn, Keith T. Wilson

Source: Amino Acids, Vol 56, Iss 1, Pp 1-12 (2024)

Subject Terms: Cystathionine g-lyase, Inflammatory bowel disease, Colitis, Colitis-associated carcinogenesis, Cysteine, Gut microbiota, Biochemistry, QD415-436, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1438-2199

Access URL: https://doaj.org/article/699bc7b9acaf4d59bea2765f7ec37397

Hypusination in intestinal epithelial cells protects mice from infectious colitis

Authors: Alain P. Gobert, Caroline V. Hawkins, Kamery J. Williams, Lydia A. Snyder, Daniel P. Barry, Mohammad Asim, Margaret M. Allaman, Kara M. McNamara, Alberto G. Delgado, Yu Wang, Shilin Zhao, Kristie L. Rose, M. Blanca Piazuelo, Keith T. Wilson

Source: Gut Microbes, Vol 16, Iss 1 (2024)

Subject Terms: Polyamines, hypusine, translation, attaching and effacing pathogen, Enteropathogenic Escherichia coli, Citrobacter rodentium, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/2fb1850dd0fb406b991131a6758490a3

Cystathionine γ-lyase exacerbates Helicobacter pylori immunopathogenesis by promoting macrophage metabolic remodeling and activation

Authors: Yvonne L. Latour, Johanna C. Sierra, Jordan L. Finley, Mohammad Asim, Daniel P. Barry, Margaret M. Allaman, Thaddeus M. Smith, Kara M. McNamara, Paula B. Luis, Claus Schneider, Justin Jacobse, Jeremy A. Goettel, M. Wade Calcutt, Kristie L. Rose, Kevin L. Schey, Ginger L. Milne, Alberto G. Delgado, M. Blanca Piazuelo, Bindu D. Paul, Solomon H. Snyder, Alain P. Gobert, Keith T. Wilson

Source: JCI Insight, Vol 7, Iss 12 (2022)

Subject Terms: Gastroenterology, Immunology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/19c8a2f445654133870ff2cc83d6103c

Curcumin Oxidation Is Required for Inhibition of Helicobacter pylori Growth, Translocation and Phosphorylation of Cag A

Authors: Ashwini Kumar Ray, Paula B. Luis, Surabhi Kirti Mishra, Daniel P. Barry, Mohammad Asim, Achyut Pandey, Maya Chaturvedi, Jyoti Gupta, Shilpi Gupta, Shweta Mahant, Rajashree Das, Pramod Kumar, Shalimar, Keith T. Wilson, Claus Schneider, Rupesh Chaturvedi

Source: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)

Subject Terms: curcumin, metabolic transformation, reduced curcumin, Helicobacter pylori, CagA, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2021.765842/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/a622bfe04d9949218af2562065f003bf

Hypusination Orchestrates the Antimicrobial Response of Macrophages

Authors: Alain P. Gobert, Jordan L. Finley, Yvonne L. Latour, Mohammad Asim, Thaddeus M. Smith, Thomas G. Verriere, Daniel P. Barry, Margaret M. Allaman, Alberto G. Delagado, Kristie L. Rose, M. Wade Calcutt, Kevin L. Schey, Johanna C. Sierra, M. Blanca Piazuelo, Raghavendra G. Mirmira, Keith T. Wilson

Source: Cell Reports, Vol 33, Iss 11, Pp 108510- (2020)

Subject Terms: macrophages, bacterial infection, innate immunity, hypusine, polyamines, Helicobacter pylori, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124720314996; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/c676099b79ac40018987909502fd92db

Bacterial Pathogens Hijack the Innate Immune Response by Activation of the Reverse Transsulfuration Pathway

Authors: Alain P. Gobert, Yvonne L. Latour, Mohammad Asim, Jordan L. Finley, Thomas G. Verriere, Daniel P. Barry, Ginger L. Milne, Paula B. Luis, Claus Schneider, Emilio S. Rivera, Kristie Lindsey-Rose, Kevin L. Schey, Alberto G. Delgado, Johanna C. Sierra, M. Blanca Piazuelo, Keith T. Wilson

Source: mBio, Vol 10, Iss 5 (2019)

Subject Terms: Helicobacter pylori, immune evasion, immunometabolism, innate immunity, macrophages, pathogenic bacteria, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/db50a92f548d4b85beae15ff68935760

Dietary Arginine Regulates Severity of Experimental Colitis and Affects the Colonic Microbiome

Authors: Kshipra Singh, Alain P. Gobert, Lori A. Coburn, Daniel P. Barry, Margaret Allaman, Mohammad Asim, Paula B. Luis, Claus Schneider, Ginger L. Milne, Helen H. Boone, Meghan H. Shilts, M. Kay Washington, Suman R. Das, M. Blanca Piazuelo, Keith T. Wilson

Source: Frontiers in Cellular and Infection Microbiology, Vol 9 (2019)

Subject Terms: arginine, experimental colitis, gut microbiota, alternative therapies, inflammatory bowel diseases, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fcimb.2019.00066/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/7155bb0c4fa443f19d5c19bdc86dbe65

Distinct Immunomodulatory Effects of Spermine Oxidase in Colitis Induced by Epithelial Injury or Infection

Authors: Alain P. Gobert, Nicole T. Al-Greene, Kshipra Singh, Lori A. Coburn, Johanna C. Sierra, Thomas G. Verriere, Paula B. Luis, Claus Schneider, Mohammad Asim, Margaret M. Allaman, Daniel P. Barry, John L. Cleveland, Christina E. Destefano Shields, Robert A. Casero, M. Kay Washington, M. Blanca Piazuelo, Keith T. Wilson

Source: Frontiers in Immunology, Vol 9 (2018)

Subject Terms: colitis, infection, polyamines, spermidine, spermine oxidase, mucosal immune response, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2018.01242/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/740a25b20113470485090afbaa34d653