Stress-induced reversible cell-cycle arrest requires PRC2/PRC1-mediated control of mitophagy in Drosophila germline stem cells and human iPSCs

Authors: Tommy H. Taslim, Abdiasis M. Hussein, Riya Keshri, Julien R. Ishibashi, Tung C. Chan, Bich N. Nguyen, Shuozhi Liu, Daniel Brewer, Stuart Harper, Scott Lyons, Ben Garver, Jimmy Dang, Nanditaa Balachandar, Samriddhi Jhajharia, Debra del Castillo, Julie Mathieu, Hannele Ruohola-Baker

Source: Stem Cell Reports, Vol 18, Iss 1, Pp 269-288 (2023)

Subject Terms: mitochondria, cyclin E, mitophagy, mTOR, pluripotent stem cells, epigenetic, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671122005379; https://doaj.org/toc/2213-6711

Access URL: https://doaj.org/article/eb6bd65efcdf4b1b88df9fdd967d7c49

A urine-based DNA methylation assay, ProCUrE, to identify clinically significant prostate cancer

Authors: Fang Zhao, Ekaterina Olkhov-Mitsel, Shivani Kamdar, Renu Jeyapala, Julia Garcia, Rachel Hurst, Marcelino Yazbek Hanna, Robert Mills, Alexandra V. Tuzova, Eve O’Reilly, Sarah Kelly, Colin Cooper, The Movember Urine Biomarker Consortium, Daniel Brewer, Antoinette S. Perry, Jeremy Clark, Neil Fleshner, Bharati Bapat

Source: Clinical Epigenetics, Vol 10, Iss 1, Pp 1-12 (2018)

Subject Terms: Prostate cancer, PSA, Urine, DNA methylation, Biomarker, Early detection, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s13148-018-0575-z; https://doaj.org/toc/1868-7075; https://doaj.org/toc/1868-7083

Access URL: https://doaj.org/article/0ba5aac33c664dcd9ecbe8bd9de7e992

Transcriptome-Wide Effects of Sphingosine Kinases Knockdown in Metastatic Prostate and Breast Cancer Cells: Implications for Therapeutic Targeting

Authors: Heba Alshaker, Qi Wang, Daniel Brewer, Dmitri Pchejetski

Source: Frontiers in Pharmacology, Vol 10 (2019)

Subject Terms: sphingosine kinase, gene knockdown, DNA microarray, transcriptome, breast cancer, prostate cancer, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2019.00303/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/52472b2d4b03405a9e4478a93511973c

Consumption and emotions among college students toward chocolate product

Authors: Carla Velarde, Amy Moore, Eric Adjei Boakye, Todd Parkhurst, Daniel Brewer

Source: Cogent Food & Agriculture, Vol 4, Iss 1 (2018)

Subject Terms: chocolate consumption, college students, emotions, nutrition counseling, Agriculture, Food processing and manufacture, TP368-456

File Description: electronic resource

Relation: https://doaj.org/toc/2331-1932

Access URL: https://doaj.org/article/79f6f907a5824892a65de287a151afaa

Dissection of a complex transcriptional response using genome‐wide transcriptional modelling

Authors: Martino Barenco, Daniel Brewer, Efterpi Papouli, Daniela Tomescu, Robin Callard, Jaroslav Stark, Michael Hubank

Source: Molecular Systems Biology, Vol 5, Iss 1, Pp 1-15 (2009)

Subject Terms: modelling, transcription, microarrays, transcription factor activity, Biology (General), QH301-705.5, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/1744-4292

Access URL: https://doaj.org/article/c459a40efde04174ad430bf39e65cdcf

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

Authors: Young Seok Ju, Ludmil B Alexandrov, Moritz Gerstung, Inigo Martincorena, Serena Nik-Zainal, Manasa Ramakrishna, Helen R Davies, Elli Papaemmanuil, Gunes Gundem, Adam Shlien, Niccolo Bolli, Sam Behjati, Patrick S Tarpey, Jyoti Nangalia, Charles E Massie, Adam P Butler, Jon W Teague, George S Vassiliou, Anthony R Green, Ming-Qing Du, Ashwin Unnikrishnan, John E Pimanda, Bin Tean Teh, Nikhil Munshi, Mel Greaves, Paresh Vyas, Adel K El-Naggar, Tom Santarius, V Peter Collins, Richard Grundy, Jack A Taylor, D Neil Hayes, David Malkin, ICGC Breast Cancer Group, ICGC Chronic Myeloid Disorders Group, ICGC Prostate Cancer Group, Christopher S Foster, Anne Y Warren, Hayley C Whitaker, Daniel Brewer, Rosalind Eeles, Colin Cooper, David Neal, Tapio Visakorpi, William B Isaacs, G Steven Bova, Adrienne M Flanagan, P Andrew Futreal, Andy G Lynch, Patrick F Chinnery, Ultan McDermott, Michael R Stratton, Peter J Campbell

Source: eLife, Vol 3 (2014)

Subject Terms: mitochondrial DNA, somatic mutation, mutational signature, cancer genome, evolution, sequencing, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/02935; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/a97bb2e0fa0f4eb19b17cd3f405b0385

siRNA knockdown of ribosomal protein gene RPL19 abrogates the aggressive phenotype of human prostate cancer.

Authors: Alix Bee, Daniel Brewer, Carol Beesley, Andrew Dodson, Shiva Forootan, Timothy Dickinson, Patricia Gerard, Brian Lane, Sheng Yao, Colin S Cooper, Mustafa B A Djamgoz, Christine M Gosden, Youqiang Ke, Christopher S Foster

Source: PLoS ONE, Vol 6, Iss 7, p e22672 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3142177?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/25562c9e84f341729fae58538863a1cf

Interlaboratory and Interplatform Comparison of Microarray Gene Expression Analysis of HepG2 Cells Exposed to Benzo(a)pyrene.

Authors: Sarah L. Hockley, Karen Mathijs, Yvonne C.M. Staal, Daniel Brewer, Ian Giddings, Joost H.M. van Delft, David H. Phillips

Source: OMICS: A Journal of Integrative Biology; Apr2009, Vol. 13 Issue 2, p115-125, 11p

Fitting ordinary differential equations to short time course data.

Authors: Daniel Brewer, Martino Barenco, Robin Callard, Michael Hubank, Jaroslav Stark

Source: Philosophical Transactions of the Royal Society A: Mathematical, Physical & Engineering Sciences. Feb2008, Vol. 366 Issue 1865, p519-544. 26p.

Subject Terms: *DIFFERENTIAL equations, *SYSTEMS theory, *STATISTICAL correlation, *MISSING data (Statistics)

AHR- and DNA-Damage-Mediated Gene Expression Responses Induced by Benzo(a)pyrene in Human Cell Lines.

Authors: Sarah L. Hockley, Volker M. Arlt, Daniel Brewer, Robert te Poele, Paul Workman, Ian Giddings, David H. Phillips

Source: Chemical Research in Toxicology; Oct2007, Vol. 20 Issue 12, p1797-1810, 14p

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