Whole-exome profiles of inflammatory breast cancer and pathological response to neoadjuvant chemotherapy

Authors: François Bertucci, Arnaud Guille, Florence Lerebours, Michele Ceccarelli, Najeeb Syed, José Adélaïde, Pascal Finetti, Naoto T. Ueno, Steven Van Laere, Patrice Viens, Alexandre De Nonneville, Anthony Goncalves, Daniel Birnbaum, Céline Callens, Davide Bedognetti, Emilie Mamessier

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)

Subject Terms: Inflammatory breast cancer, Copy number alteration, Mutation, Whole-exome sequencing, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/1068ae1848944ff180c01ffd49e76be5

Mutational landscape of inflammatory breast cancer

Authors: François Bertucci, Florence Lerebours, Michele Ceccarelli, Arnaud Guille, Najeeb Syed, Pascal Finetti, José Adélaïde, Steven Van Laere, Anthony Goncalves, Patrice Viens, Daniel Birnbaum, Emilie Mamessier, Céline Callens, Davide Bedognetti

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)

Subject Terms: Inflammatory breast cancer, Copy number alteration, Mutation, Whole-exome sequencing, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/d411209f682649f3b4011eb089a7cbba

Immunologic constant of rejection as a predictive biomarker of immune checkpoint inhibitors efficacy in non-small cell lung cancer

Authors: Alice Mogenet, Pascal Finetti, Emilie Denicolai, Laurent Greillier, Pascaline Boudou-Rouquette, François Goldwasser, Gwenael Lumet, Michele Ceccarelli, Daniel Birnbaum, Davide Bedognetti, Emilie Mamessier, Fabrice Barlesi, François Bertucci, Pascale Tomasini

Source: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-11 (2023)

Subject Terms: Lung cancer, ICR signature, Immune therapy, Biomarkers, Immune checkpoints inhibitors, Transcriptomics, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/67108f51d6d841e88d4d580890ae1436

Erythroleukemia: Classification

Authors: Nathalie Cervera, Arnaud Guille, José Adélaïde, Marie‐Anne Hospital, Sylvain Garciaz, Marie‐Joelle Mozziconacci, Norbert Vey, Véronique Gelsi‐Boyer, Daniel Birnbaum

Source: eJHaem, Vol 4, Iss 2, Pp 450-453 (2023)

Subject Terms: acute erythroid leukemia, molecular classification, mutations, TP53, Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://doaj.org/toc/2688-6146

Access URL: https://doaj.org/article/d6312bdd72cb46629c506d098c5d8cc2

CSPG4 expression in soft tissue sarcomas is associated with poor prognosis and low cytotoxic immune response

Authors: Laurys Boudin, A de Nonneville, Pascal Finetti, Léna Mescam, A Le Cesne, Antoine Italiano, Jean-Yves Blay, Daniel Birnbaum, Emilie Mamessier, François Bertucci

Source: Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-13 (2022)

Subject Terms: Soft tissue sarcomas, CSPG4, Immune response, Immune therapy, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/f6527691660149788a4e90bf8c5daef5

Low cholesterol biosynthesis favors epithelial‐to‐mesenchymal transition maintenance and influences tumor molecular subtyping and disease‐free survival in colon cancer patients

Authors: Anaïs Aulas, Maria Lucia Liberatoscioli, Pascal Finetti, Olivier Cabaud, David J. Birnbaum, Lucas Usclade, Daniel Birnbaum, François Bertucci, Emilie Mamessier

Source: Cancer Communications, Vol 42, Iss 8, Pp 793-797 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2523-3548

Access URL: https://doaj.org/article/491aad5dabbe4e17a539f8d05f24f971

TOP3A amplification and ATRX inactivation are mutually exclusive events in pediatric osteosarcomas using ALT

Authors: Alexandre de Nonneville, Sébastien Salas, François Bertucci, Alexander P Sobinoff, José Adélaïde, Arnaud Guille, Pascal Finetti, Jane R Noble, Dimitri Churikov, Max Chaffanet, Elise Lavit, Hilda A Pickett, Corinne Bouvier, Daniel Birnbaum, Roger R Reddel, Vincent Géli

Source: EMBO Molecular Medicine, Vol 14, Iss 10, Pp 1-22 (2022)

Subject Terms: alternative lengthening of telomeres, ATRX, osteosarcomas, telomeres, TOP3A, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/948680b27447452fa822018d83b4b8e5

BMI1 nuclear location is critical for RAD51-dependent response to replication stress and drives chemoresistance in breast cancer stem cells

Authors: Violette Azzoni, Julien Wicinski, Manon Macario, Martin Castagné, Pascal Finetti, Katerina Ambrosova, Célia D. Rouault, Arnaud Sergé, Anne Farina, Emilie Agavnian, Sergiu Coslet, Emmanuelle Josselin, Arnaud Guille, José Adelaide, Emmanouil Zacharioudakis, Rémy Castellano, Francois Bertucci, Daniel Birnbaum, Raphael Rodriguez, Emmanuelle Charafe-Jauffret, Christophe Ginestier

Source: Cell Death and Disease, Vol 13, Iss 2, Pp 1-15 (2022)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/41f1ef2e00194644a397b32092889d81

BRCA1-methylated triple negative breast cancers previously exposed to neoadjuvant chemotherapy form RAD51 foci and respond poorly to olaparib

Authors: Carolina Velazquez, Esin Orhan, Imene Tabet, Lise Fenou, Béatrice Orsetti, José Adélaïde, Arnaud Guille, Simon Thézénas, Evelyne Crapez, Pierre-Emmanuel Colombo, Max Chaffanet, Daniel Birnbaum, Claude Sardet, William Jacot, Charles Theillet

Source: Frontiers in Oncology, Vol 13 (2023)

Subject Terms: TNBC, BRCA1 methylation, RAD51, nuclear foci, HRD (homologous recombination deficiency), Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2023.1125021/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/e04a4c983fe14d5c8fffd7f0ddb98082

Comparative transcriptional analyses of preclinical models and patient samples reveal MYC and RELA driven expression patterns that define the molecular landscape of IBC

Authors: Charlotte Rypens, François Bertucci, Pascal Finetti, Fredika Robertson, Sandra V. Fernandez, Naoto Ueno, Wendy A. Woodward, Kenneth Van Golen, Peter Vermeulen, Luc Dirix, Patrice Viens, Daniel Birnbaum, Gayathri R. Devi, Massimo Cristofanilli, Steven Van Laere

Source: npj Breast Cancer, Vol 8, Iss 1, Pp 1-12 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2374-4677

Access URL: https://doaj.org/article/5f7d6093dd1c479cb755cd0da5f6d23f

Prospective high-throughput genome profiling of advanced cancers: results of the PERMED-01 clinical trial

Authors: François Bertucci, Anthony Gonçalves, Arnaud Guille, José Adelaïde, Séverine Garnier, Nadine Carbuccia, Emilien Billon, Pascal Finetti, Patrick Sfumato, Audrey Monneur, Christophe Pécheux, Martin Khran, Serge Brunelle, Lenaïg Mescam, Jeanne Thomassin-Piana, Flora Poizat, Emmanuelle Charafe-Jauffret, Olivier Turrini, Eric Lambaudie, Magali Provansal, Jean-Marc Extra, Anne Madroszyk, Marine Gilabert, Renaud Sabatier, Cécile Vicier, Emilie Mamessier, Christian Chabannon, Jihane Pakradouni, Patrice Viens, Fabrice André, Gwenaelle Gravis, Cornel Popovici, Daniel Birnbaum, Max Chaffanet

Source: Genome Medicine, Vol 13, Iss 1, Pp 1-20 (2021)

Subject Terms: aCGH, Advanced cancers, Mutation, PERMED-01 trial, Precision medicine, Sequencing, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/685cee8dc4e4477fb464978bcebb91ff

The CINSARC signature predicts the clinical outcome in patients with Luminal B breast cancer

Authors: Anthony Goncalves, Pascal Finetti, Daniel Birnbaum, François Bertucci

Source: npj Breast Cancer, Vol 7, Iss 1, Pp 1-9 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2374-4677

Access URL: https://doaj.org/article/ecafbdc5cfd6482fbd26fa13182d387e

EFA6B regulates a stop signal for collective invasion in breast cancer

Authors: Racha Fayad, Monserrat Vázquez Rojas, Mariagrazia Partisani, Pascal Finetti, Shiraz Dib, Sophie Abelanet, Virginie Virolle, Anne Farina, Olivier Cabaud, Marc Lopez, Daniel Birnbaum, François Bertucci, Michel Franco, Frédéric Luton

Source: Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/0787bba0953b47b2823c7bc21ef9994c

Clinical and genomic analysis of a large Chinese family with familial cortical myoclonic tremor with epilepsy and SAMD12 intronic repeat expansion

Authors: Yongxing Zhou, Raman Sood, Qun Wang, Blake Carrington, Morgan Park, Alice C. Young, Daniel Birnbaum, Zhao Liu, Tetsuo Ashizawa, James C. Mullikin, Mohamad Z. Koubeissi, Paul Liu

Source: Epilepsia Open, Vol 6, Iss 1, Pp 102-111 (2021)

Subject Terms: epilepsy, FCMTE, myoclonus, SAMD12, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2470-9239

Access URL: https://doaj.org/article/d7380d695a6f4adcaf36dcac20e3d784

Whole-genome/exome analysis of circulating tumor DNA and comparison to tumor genomics from patients with heavily pre-treated ovarian cancer: subset analysis of the PERMED-01 trial

Authors: Renaud Sabatier, Séverine Garnier, Arnaud Guille, Nadine Carbuccia, Jihane Pakradouni, José Adelaide, Magali Provansal, Maria Cappiello, Frédérique Rousseau, Max Chaffanet, Daniel Birnbaum, Emilie Mamessier, Anthony Gonçalves, François Bertucci

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: ovarian cancer, circulating tumor DNA, low-coverage whole-genome sequencing, copy number alterations, whole-exome sequencing, mutations, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.946257/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/e8ca0d11810341ec999c93a85f969100

ZNF703 mRNA-Targeting Antisense Oligonucleotide Blocks Cell Proliferation and Induces Apoptosis in Breast Cancer Cell Lines

Authors: Sandra Udu-Ituma, José Adélaïde, Thi Khanh Le, Kenneth Omabe, Pascal Finetti, Clément Paris, Arnaud Guille, François Bertucci, Daniel Birnbaum, Palma Rocchi, Max Chaffanet

Source: Pharmaceutics, Vol 15, Iss 7, p 1930 (2023)

Subject Terms: ZNF703, luminal B breast cancer, antisense oligonucleotides, apoptosis, cisplatin, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/7/1930; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/6ce250a765aa49609d7037ef5f6e3b22

Prognostic and Predictive Value of LIV1 Expression in Early Breast Cancer and by Molecular Subtype

Authors: Alexandre de Nonneville, Pascal Finetti, Laurys Boudin, Emilie Denicolaï, Daniel Birnbaum, Emilie Mamessier, François Bertucci

Source: Pharmaceutics, Vol 15, Iss 3, p 938 (2023)

Subject Terms: LIV1, SLC39A6, ZIP6, breast cancer, antibody–drug conjugates, zinc transporter protein, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/3/938; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/488472c972ca4775876116771040c065

Immunologic constant of rejection signature is prognostic in soft-tissue sarcoma and refines the CINSARC signature

Authors: Jean-Yves Blay, Antoine Italiano, Axel Le Cesne, Olivier Mir, Davide Bedognetti, Michele Ceccarelli, Pascal Finetti, Daniel Birnbaum, Francois Bertucci, Emilie Mamessier, Vincent Niziers, Alexandre de Nonneville, Léna Mescam

Source: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/10/1/e003687.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/e01db99505404ed38306ed436f910b5a

NOTCH and DNA repair pathways are more frequently targeted by genomic alterations in inflammatory than in non‐inflammatory breast cancers

Authors: François Bertucci, Charlotte Rypens, Pascal Finetti, Arnaud Guille, José Adélaïde, Audrey Monneur, Nadine Carbuccia, Séverine Garnier, Piet Dirix, Anthony Gonçalves, Peter Vermeulen, Bisrat G. Debeb, Xiaoping Wang, Luc Dirix, Naoto T. Ueno, Patrice Viens, Massimo Cristofanilli, Max Chaffanet, Daniel Birnbaum, Steven Van Laere

Source: Molecular Oncology, Vol 14, Iss 3, Pp 504-519 (2020)

Subject Terms: copy number profiling, DNA repair, inflammatory breast cancer, NOTCH, sequencing, targeted therapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1574-7891; https://doaj.org/toc/1878-0261

Access URL: https://doaj.org/article/4432b063855f42719a19cc390e05d2c5

A genome‐wide RNAi screen reveals essential therapeutic targets of breast cancer stem cells

Authors: Abir Arfaoui, Claire Rioualen, Violette Azzoni, Guillaume Pinna, Pascal Finetti, Julien Wicinski, Emmanuelle Josselin, Manon Macario, Rémy Castellano, Candi Léonard‐Stumpf, Anthony Bal, Abigaelle Gros, Sylvain Lossy, Maher Kharrat, Yves Collette, Francois Bertucci, Daniel Birnbaum, Hayet Douik, Ghislain Bidaut, Emmanuelle Charafe‐Jauffret, Christophe Ginestier

Source: EMBO Molecular Medicine, Vol 11, Iss 10, Pp 1-18 (2019)

Subject Terms: breast cancer, cancer stem cells, JQ1, RNAi screen, salinomycin, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1757-4676; https://doaj.org/toc/1757-4684

Access URL: https://doaj.org/article/c9002abaa4bb472dafea9936d6b75e8c