Distinct epigenomic landscapes underlie tissue-specific memory T cell differentiation

Authors: Buquicchio, Frank A., Fonseca, Raissa, Yan, Patrick K., Wang, Fangyi, Evrard, Maximilien, Obers, Andreas, Gutierrez, Jacob C., Raposo, Colin J., Belk, Julia A., Daniel, Bence, Zareie, Pirooz, Yost, Kathryn E., Qi, Yanyan, Yin, Yajie, Nico, Katherine F., Tierney, Flora M., Howitt, Michael R., Lareau, Caleb A., Satpathy, Ansuman T., Mackay, Laura K.

Source: In Immunity 10 September 2024 57(9):2202-2215

Inosine induces stemness features in CAR-T cells and enhances potency

Authors: Klysz, Dorota D., Fowler, Carley, Malipatlolla, Meena, Stuani, Lucille, Freitas, Katherine A., Chen, Yiyun, Meier, Stefanie, Daniel, Bence, Sandor, Katalin, Xu, Peng, Huang, Jing, Labanieh, Louai, Keerthi, Vimal, Leruste, Amaury, Bashti, Malek, Mata-Alcazar, Janette, Gkitsas, Nikolaos, Guerrero, Justin A., Fisher, Chris, Patel, Sunny, Asano, Kyle, Patel, Shabnum, Davis, Kara L., Satpathy, Ansuman T., Feldman, Steven A., Sotillo, Elena, Mackall, Crystal L.

Source: In Cancer Cell 12 February 2024 42(2):266-282

Modular pooled discovery of synthetic knockin sequences to program durable cell therapies

Authors: Blaeschke, Franziska, Chen, Yan Yi, Apathy, Ryan, Daniel, Bence, Chen, Andy Y., Chen, Peixin Amy, Sandor, Katalin, Zhang, Wenxi, Li, Zhongmei, Mowery, Cody T., Yamamoto, Tori N., Nyberg, William A., To, Angela, Yu, Ruby, Bueno, Raymund, Kim, Min Cheol, Schmidt, Ralf, Goodman, Daniel B., Feuchtinger, Tobias, Eyquem, Justin, Jimmie Ye, Chun, Carnevale, Julia, Satpathy, Ansuman T., Shifrut, Eric, Roth, Theodore L., Marson, Alexander

Source: In Cell 14 September 2023 186(19):4216-4234

Macrophage inflammatory and regenerative response periodicity is programmed by cell cycle and chromatin state

Authors: Daniel, Bence, Belk, Julia A., Meier, Stefanie L., Chen, Andy Y., Sandor, Katalin, Czimmerer, Zsolt, Varga, Zsofia, Bene, Krisztian, Buquicchio, Frank A., Qi, Yanyan, Kitano, Hugo, Wheeler, Joshua R., Foster, Deshka S., Januszyk, Michael, Longaker, Michael T., Chang, Howard Y., Satpathy, Ansuman T.

Source: In Molecular Cell 5 January 2023 83(1):121-138

BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen

Authors: Xia, Yu, Sandor, Katalin, Pai, Joy A., Daniel, Bence, Raju, Saravanan, Wu, Renee, Hsiung, Sunnie, Qi, Yanyan, Yangdon, Tenzin, Okamoto, Mariko, Chou, Chun, Hiam-Galvez, Kamir J., Schreiber, Robert D., Murphy, Kenneth M., Satpathy, Ansuman T., Egawa, Takeshi

Source: In Immunity 12 July 2022 55(7):1200-1215

Genome-wide CRISPR screens of T cell exhaustion identify chromatin remodeling factors that limit T cell persistence

Authors: Belk, Julia A., Yao, Winnie, Ly, Nghi, Freitas, Katherine A., Chen, Yan-Ting, Shi, Quanming, Valencia, Alfredo M., Shifrut, Eric, Kale, Nupura, Yost, Kathryn E., Duffy, Connor V., Daniel, Bence, Hwee, Madeline A., Miao, Zhuang, Ashworth, Alan, Mackall, Crystal L., Marson, Alexander, Carnevale, Julia, Vardhana, Santosh A., Satpathy, Ansuman T.

Source: In Cancer Cell 11 July 2022 40(7):768-786

Global Run-on Sequencing (GRO-Seq)

Authors: Tzerpos, Petros, Daniel, Bence, Nagy, Laszlo

Source: Methods in molecular biology. 2351:25-40

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN627385857&indx=1&recIds=ETOCRN627385857

Identification of a T-bet^h^i Quiescent Exhausted CD8 T Cell Subpopulation That Can Differentiate into TIM3^+CX3CR1^+ Effectors and Memory-like Cells

Authors: Raju, Saravanan, Xia, Yu, Daniel, Bence, Yost, Kathryn E., Bradshaw, Elliot, Tone, Elena, Verbaro, Daniel J., Kometani, Kohei, Yokoyama, Wayne M., Kurosaki, Tomohiro

Source: Journal of immunology. 206(12):2924-2936

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN626947140&indx=1&recIds=ETOCRN626947140

The transcription factor EGR2 is the molecular linchpin connecting STAT6 activation to the late, stable epigenomic program of alternative macrophage polarization

Authors: Daniel, Bence, Czimmerer, Zsolt, Halasz, Laszlo, Boto, Pal, Kolostyak, Zsuzsanna, Poliska, Szilard, Berger, Wilhelm K., Tzerpos, Petros, Nagy, Gergely, Horvath, Attila

Source: Genes & development. 34(21/22):1474-1492

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625176345&indx=1&recIds=ETOCRN625176345

Hepatocyte-Macrophage Acetoacetate Shuttle Protects against Tissue Fibrosis

Authors: Puchalska, Patrycja, Martin, Shannon E., Huang, Xiaojing, Lengfeld, Justin E., Daniel, Bence, Graham, Mark J., Han, Xianlin, Nagy, Laszlo, Patti, Gary J., Crawford, Peter A.

Source: In Cell Metabolism 5 February 2019 29(2):383-398

Extensive and functional overlap of the STAT6 and RXR cistromes in the active enhancer repertoire of human CD14+ monocyte derived differentiating macrophages

Authors: Czimmerer, Zsolt, Nagy, Zsuzsanna S., Nagy, Gergely, Horvath, Attila, Silye-Cseh, Timea, Kriston, Agnes, Jonas, David, Sauer, Sascha, Steiner, Laszlo, Daniel, Bence, Deleuze, Jean-Francois, Nagy, Laszlo

Source: In Molecular and Cellular Endocrinology 15 August 2018 471:63-74

The Transcription Factor STAT6 Mediates Direct Repression of Inflammatory Enhancers and Limits Activation of Alternatively Polarized Macrophages

Authors: Czimmerer, Zsolt, Daniel, Bence, Horvath, Attila, Rückerl, Dominik, Nagy, Gergely, Kiss, Mate, Peloquin, Matthew, Budai, Marietta M., Cuaranta-Monroy, Ixchelt, Simandi, Zoltan, Steiner, Laszlo, Nagy, Bela, Jr., Poliska, Szilard, Banko, Csaba, Bacso, Zsolt, Schulman, Ira G., Sauer, Sascha, Deleuze, Jean-Francois, Allen, Judith E., Benko, Szilvia, Nagy, Laszlo

Source: In Immunity 16 January 2018 48(1):75-90

Dynamic transcriptional control of macrophage miRNA signature via inflammation responsive enhancers revealed using a combination of next generation sequencing-based approaches

Authors: Czimmerer, Zsolt, Horvath, Attila, Daniel, Bence, Nagy, Gergely, Cuaranta-Monroy, Ixchelt, Kiss, Mate, Kolostyak, Zsuzsanna, Poliska, Szilard, Steiner, Laszlo, Giannakis, Nikolas, Varga, Tamas, Nagy, Laszlo

Source: In BBA - Gene Regulatory Mechanisms January 2018 1861(1):14-28

The epigenetic state of IL-4-polarized macrophages enables inflammatory cistromic expansion and extended synergistic response to TLR ligands

Authors: Czimmerer, Zsolt, Halasz, Laszlo, Daniel, Bence, Varga, Zsofia, Bene, Krisztian, Domokos, Apolka, Hoeksema, Marten, Shen, Zeyang, Berger, Wilhelm K., Cseh, Timea, Jambrovics, Karoly, Kolostyak, Zsuzsanna, Fenyvesi, Ferenc, Varadi, Judit, Poliska, Szilard, Hajas, Gyorgy, Szatmari, Istvan, Glass, Christopher K., Bacsi, Attila, Nagy, Laszlo

Source: Immunity. 55(11):2006-2026.e6

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100186605637.0x000001&indx=1&recIds=ETOCvdc_100186605637.0x000001

Retinoid X receptor suppresses a metastasis-promoting transcriptional program in myeloid cells via a ligand-insensitive mechanism

Authors: Kiss, Mate, Czimmerer, Zsolt, Nagy, Gergely, Bieniasz-Krzywiec, Pawel, Ehling, Manuel, Pap, Attila, Poliska, Szilard, Boto, Pal, Tzerpos, Petros, Horvath, Attila, Kolostyak, Zsuzsanna, Daniel, Bence, Szatmari, Istvan, Mazzone, Massimiliano, Nagy, Laszlo

Source: Proceedings of the National Academy of Sciences of the United States of America, 2017 Oct 01. 114(40), 10725-10730.

Access URL: https://www.jstor.org/stable/26488124

FOXO1 is a master regulator of memory programming in CAR T cells.

Authors: Doan, Alexander E., Mueller, Katherine P., Chen, Andy Y., Rouin, Geoffrey T., Chen, Yingshi, Daniel, Bence, Lattin, John, Markovska, Martina, Mozarsky, Brett, Arias-Umana, Jose, Hapke, Robert, Jung, In-Young, Wang, Alice, Xu, Peng, Klysz, Dorota, Zuern, Gabrielle, Bashti, Malek, Quinn, Patrick J., Miao, Zhuang, Sandor, Katalin

Source: Nature; May2024, Vol. 629 Issue 8010, p211-218, 8p

Macrophage PPARγ, a Lipid Activated Transcription Factor Controls the Growth Factor GDF3 and Skeletal Muscle Regeneration

Authors: Varga, Tamas, Mounier, Rémi, Patsalos, Andreas, Gogolák, Péter, Peloquin, Matthew, Horvath, Attila, Pap, Attila, Daniel, Bence, Nagy, Gergely, Pintye, Eva, Poliska, Szilárd, Cuvellier, Sylvain, Ben Larbi, Sabrina, Sansbury, Brian E., Spite, Matthew, Brown, Chester W., Chazaud, Bénédicte, Nagy, Laszlo

Source: In Immunity 15 November 2016 45(5):1038-1051

SETDB2 Links Glucocorticoid to Lipid Metabolism through Insig2a Regulation

Authors: Roqueta-Rivera, Manuel, Esquejo, Ryan M., Phelan, Peter E., Sandor, Katalin, Daniel, Bence, Foufelle, Fabienne, Ding, Jun, Li, Xiaoman, Khorasanizadeh, Sepideh, Osborne, Timothy F.

Source: In Cell Metabolism 13 September 2016 24(3):474-484

Transcriptional control of transglutaminase 2 expression in mouse apoptotic thymocytes

Authors: Sándor, Katalin, Daniel, Bence, Kiss, Bea, Kovács, Fruzsina, Szondy, Zsuzsa

Source: In BBA - Gene Regulatory Mechanisms August 2016 1859(8):964-974

An Atlas of Promoter Chromatin Modifications and HiChIP Regulatory Interactions in Human Subcutaneous Adipose-Derived Stem Cells.

Authors: Halasz, Laszlo, Divoux, Adeline, Sandor, Katalin, Erdos, Edina, Daniel, Bence, Smith, Steven R., Osborne, Timothy F.

Source: International Journal of Molecular Sciences; Jan2024, Vol. 25 Issue 1, p437, 35p

Subject Terms: STEM cells, EPIGENOMICS, ABDOMINAL adipose tissue, HUMAN stem cells, SOCIAL interaction, GENE expression