Graft dysfunction in compassionate use of genetically engineered pig-to-human cardiac xenotransplantation: a case report

Authors: Mohiuddin, Muhammad M, Singh, Avneesh K, Scobie, Linda, Goerlich, Corbin E, Grazioli, Alison, Saharia, Kapil, Crossan, Claire, Burke, Allen, Drachenberg, Cinthia, Oguz, Cihan, Zhang, Tianshu, Lewis, Billeta, Hershfeld, Alena, Sentz, Faith, Tatarov, Ivan, Mudd, Sarah, Braileanu, Gheorghe, Rice, Kathryn, Paolini, John F, Bondensgaard, Kent, Vaught, Todd, Kuravi, Kasinath, Sorrells, Lori, Dandro, Amy, Ayares, David, Lau, Christine, Griffith, Bartley P

Source: Lancet. 402(10399):397-410

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Immune response after pig-to-human kidney xenotransplantation: a multimodal phenotyping study

Authors: Loupy, Alexandre ^{†, *}, Goutaudier, Valentin ^†, Giarraputo, Alessia ^†, Mezine, Fariza, Morgand, Erwan, Robin, Blaise, Khalil, Karen, Mehta, Sapna, Keating, Brendan, Dandro, Amy, Certain, Anaïs, Tharaux, Pierre-Louis, Narula, Navneet, Tissier, Renaud, Giraud, Sébastien, Hauet, Thierry, Pass, Harvey I, Sannier, Aurélie, Wu, Ming, Griesemer, Adam, Ayares, David, Tatapudi, Vasishta, Stern, Jeffrey, Lefaucheur, Carmen, Bruneval, Patrick, Mangiola, Massimo, Montgomery, Robert A

Source: In The Lancet 30 September-6 October 2023 402(10408):1158-1169

First clinical‐grade porcine kidney xenotransplant using a human decedent model

Authors: Porrett, Paige M., Orandi, Babak J., Kumar, Vineeta, Houp, Julie, Anderson, Douglas, Cozette Killian, A., Hauptfeld‐Dolejsek, Vera, Martin, Dominique E., Macedon, Sara, Budd, Natalie, Stegner, Katherine L., Dandro, Amy, Kokkinaki, Maria, Kuravi, Kasinath V., Reed, Rhiannon D., Fatima, Huma, Killian, John T., Baker, Gavin, Perry, Jackson, Wright, Emma D., Cheung, Matthew D., Erman, Elise N., Kraebber, Karl, Gamblin, Tracy, Guy, Linda, George, James F., Ayares, David, Locke, Jayme E.

Source: American journal of transplantation. 22(4):1037-1053

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Progressive genetic modifications of porcine cardiac xenografts extend survival to 9 months

Authors: Mohiuddin, Muhammad M., Goerlich, Corbin E., Singh, Avneesh K., Zhang, Tianshu, Tatarov, Ivan, Lewis, Billeta, Sentz, Faith, Hershfeld, Alena, Braileanu, Gheorghe, Odonkor, Patrick, Strauss, Erik, Williams, Brittney, Burke, Allen, Hittman, Jamie, Bhutta, Adnan, Tabatabai, Ali, Gupta, Anuj, Vaught, Todd, Sorrells, Lori, Kuravi, Kasinath, Dandro, Amy, Eyestone, Will, Kaczorowski, David J., Ayares, David, Griffith, Bartley P.

Source: Xenotransplantation. 29(3)

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Effects of human TFPI and CD47 expression and selectin and integrin inhibition during GalTKO.hCD46 pig lung perfusion with human blood

Authors: Miura, Shuhei, Habibabady, Zahra A., Pollok, Franziska, Connolly, Margaret, Pratts, Shannon, Dandro, Amy, Sorrells, Lori, Karavi, Kasinath, Phelps, Carol, Eyestone, Will, Ayares, David, Burdorf, Lars, Azimzadeh, Agnes, Pierson, Richard N.

Source: Xenotransplantation. 29(2)

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HEPCR.hTBM.hCD47.hHO‐1 with donor clodronate and DDAVP treatment improves perfusion and function of GalTKO.hCD46 porcine livers perfused with human blood

Authors: Cimeno, Arielle, Kuravi, Kasinath, Sorrells, Lori, Dandro, Amy, Sendil, Selin, Burdorf, Lars, Parsell, Dawn M., Eyestone, Will, Phelps, Carol, Ayares, David, Azimzadeh, Agnes M., Pierson, Richard N., Barth, Rolf N., LaMattina, John C.

Source: Xenotransplantation. 29(2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100146549572.0x000001&indx=1&recIds=ETOCvdc_100146549572.0x000001

Humanized von Willebrand factor reduces platelet sequestration in ex vivo and in vivo xenotransplant models

Authors: Connolly, Margaret R, Kuravi, Kasinath, Burdorf, Lars, Sorrells, Lori, Morrill, Benson, Cimeno, Arielle, Vaught, Todd, Dandro, Amy, Sendil, Selin, Habibabady, Zahra A, Monahan, Jeffery, Li, Tiezheng, LaMattina, John, Eyestone, Willard, Ayares, David, Phelps, Carol, Azimzadeh, Agnes M, Pierson, Richard N

Source: Xenotransplantation. 28(6)

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A Rapid Immunoassay for Detection of Shiga Toxin-Producing Escherichia coli Directly from Human Fecal Samples and Its Performance in Detection of Toxin Subtypes

Authors: Boone, Jeremy T., Campbell, Davina E., Dandro, Amy S., Chen, Li, Herbein, Joel F.

Source: Journal of clinical microbiology. 54(12):3056-3063

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Justification of specific genetic modifications in pigs for clinical organ xenotransplantation

Authors: Cooper, David K. C., Hara, Hidetaka, Iwase, Hayato, Yamamoto, Takayuki, Li, Qi, Ezzelarab, Mohamed, Federzoni, Elena, Dandro, Amy, Ayares, David

Source: Xenotransplantation. 26(4)

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Alpha gal allergy and its connection to cardiovascular bioprostheses

Authors: KURAVI, KASINATH, Sorrels, Lori, Dandro, Amy, Bianchi, John, Choudhary, Shailesh, Commins, Scott

Source: Journal of allergy and clinical immunology. 149(2):AB94-AB94

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Immunocompromised Ungulates

Results of Two Cases of Pig-to-Human Kidney Xenotransplantation.

Authors: Montgomery, Robert A.¹, robert.montgomery@nyulangone.org, Stern, Jeffrey M.¹, Lonze, Bonnie E.¹, Tatapudi, Vasishta S.¹, Mangiola, Massimo¹, Wu, Ming², Weldon, Elaina¹, Lawson, Nikki¹, Deterville, Cecilia¹, Dieter, Rebecca A.¹, Sullivan, Brigitte¹, Boulton, Gabriella¹, Parent, Brendan^3,4, Piper, Greta¹, Sommer, Philip⁵, Cawthon, Samantha⁶, Duggan, Erin^7,8, Ayares, David⁹, Dandro, Amy⁹, Fazio-Kroll, Ana⁹

Source: New England Journal of Medicine; 5/19/2022, Vol. 386 Issue 20, p1889-1898, 10p

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A Rapid Immunoassay for Detection of Shiga Toxin-Producing Escherichia coliDirectly from Human Fecal Samples and Its Performance in Detection of Toxin Subtypes

Authors: Boone, Jeremy T., Campbell, Davina E., Dandro, Amy S., Chen, Li, Herbein, Joel F.

Source: Journal of Clinical Microbiology; October 2016, Vol. 54 Issue: 12 p3056-3063, 8p

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