Epidemiologically relevant phthalates affect human endometrial cells in vitro through cell specific gene expression changes related to the cytoskeleton and mitochondria

Authors: Visser, Nadja, Silva, Antero Vieira, Tarvainen, Ilari, Damdimopoulos, Anastasios, Davey, Eva, Roos, Kristine, Björvang, Richelle D., Kallak, Theodora Kunovac, Lager, Susanne, Lavogina, Darja, Laws, Mary, Piltonen, Terhi, Salumets, Andres, Flaws, Jodi A., Öberg, Mattias, Velthut-Meikas, Agne, Damdimopoulou, Pauliina, Olovsson, Matts

Source: In Reproductive Toxicology September 2024 128

Exposure to the phthalate metabolite MEHP impacts survival and growth of human ovarian follicles in vitro

Authors: Panagiotou, Eleftheria Maria ^{a, g, ⁎}, Damdimopoulos, Anastasios ^c, Li, Tianyi ^{a, g}, Moussaud-Lamodière, Elisabeth ^{a, g}, Pedersen, Mikael ^d, Lebre, Filipa ^e, Pettersson, Karin ^b, Arnelo, Catarina ^b, Papaikonomou, Kiriaki ^{f, g}, Alfaro-Moreno, Ernesto ^e, Lindskog, Cecilia ^h, Svingen, Terje ^d, Damdimopoulou, Pauliina ^{a, g}

Source: In Toxicology June 2024 505

Persistent organic pollutants dysregulate energy homeostasis in human ovaries in vitro

Authors: Li, Tianyi, Björvang, Richelle D., Hao, Jie, Di Nisio, Valentina, Damdimopoulos, Anastasios, Lindskog, Cecilia, Papaikonomou, Kiriaki, Damdimopoulou, Pauliina

Source: In Environment International May 2024 187

Identification of phthalate mixture exposure targets in the human and mouse ovary in vitro

Authors: Tarvainen, Ilari, Soto, Delia A., Laws, Mary J., Björvang, Richelle D., Damdimopoulos, Anastasios, Roos, Kristine, Li, Tianyi, Kramer, Stav, Li, Zhong, Lavogina, Darja, Visser, Nadja, Kallak, Theodora K., Lager, Susanne, Gidlöf, Sebastian, Edlund, Erik, Papaikonomou, Kiriaki, Öberg, Mattias, Olovsson, Matts, Salumets, Andres, Velthut-Meikas, Agne, Flaws, Jodi A., Damdimopoulou, Pauliina

Source: In Reproductive Toxicology August 2023 119

Identification of biomarkers and outcomes of endocrine disruption in human ovarian cortex using In Vitro Models

Authors: Li, Tianyi, Vazakidou, Paraskevi, Leonards, Pim E.G., Damdimopoulos, Anastasios, Panagiotou, Eleftheria Maria, Arnelo, Catarina, Jansson, Kerstin, Pettersson, Karin, Papaikonomou, Kiriaki, van Duursen, Majorie, Damdimopoulou, Pauliina

Source: In Toxicology February 2023 485

Survivin promotes a glycolytic switch in CD4+ T cells by suppressing the transcription of PFKFB3 in rheumatoid arthritis

Authors: Erlandsson, Malin C., Andersson, Karin M.E., Oparina, Nina Y., Chandrasekaran, Venkataragavan, Saghy, Tibor, Damdimopoulos, Anastasios, Garcia-Bonete, Maria-Jose, Einbeigi, Zakaria, Silfverswärd, Sofia T., Pekna, Marcela, Katona, Gergely, Bokarewa, Maria I.

Source: In iScience 22 December 2022 25(12)

An Optimized ChIP-Seq Protocol to Determine Chromatin Binding of Estrogen Receptor Beta

Authors: Indukuri, Rajitha, Damdimopoulos, Anastasios, Williams, Cecilia

Source: Methods in molecular biology. 2418:203-222

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN628860218&indx=1&recIds=ETOCRN628860218

Vaginal Transcriptional Signatures of the Neutrophil‐Driven Immune Response Correlate With Clinical Severity During Recurrent Vulvovaginal Candidiasis.

Authors: Hasselrot, Tyra, Alvendal, Cathrin, Hunt, Sara, Boger, Mathias Franzén, Kaldhusdal, Vilde, Damdimopoulos, Anastasios, Schuppe‐Koistinen, Ina, Edfeldt, Gabriella, Bohm‐Starke, Nina, Broliden, Kristina

Source: American Journal of Reproductive Immunology; Jan2025, Vol. 93 Issue 1, p1-13, 13p

The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages

Authors: Huang, Zhiqiang, Liang, Ning, Goñi, Saioa, Damdimopoulos, Anastasios, Wang, Cheng, Ballaire, Raphaelle, Jager, Jennifer, Niskanen, Henri, Han, Hongya, Jakobsson, Tomas, Bracken, Adrian P., Aouadi, Myriam, Venteclef, Nicolas, Kaikkonen, Minna U., Fan, Rongrong, Treuter, Eckardt

Source: In Molecular Cell 4 March 2021 81(5):953-968

Genome‐wide estrogen receptor β chromatin binding in human colon cancer cells reveals its tumor suppressor activity

Authors: Indukuri, Rajitha, Jafferali, Mohammed Hakim, Song, Dandan, Damdimopoulos, Anastasios, Hases, Linnea, Zhao, Chunyan, Archer, Amena, Williams, Cecilia

Source: International journal of cancer. 149(3):692-706

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122745668.0x000001&indx=1&recIds=ETOCvdc_100122745668.0x000001

Transcriptome analysis of the epididymis from Plag1 deficient mice suggests dysregulation of sperm maturation and extracellular matrix genes

Authors: Wong, Joanne, Damdimopoulos, Anastasios, Damdimopoulou, Pauliina, Gasperoni, Jemma G., Tran, Stephanie C., Grommen, Sylvia V.H., De Groef, Bert, Dworkin, Sebastian

Source: Developmental dynamics. 249(12):1500-1513

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111806992.0x000001&indx=1&recIds=ETOCvdc_100111806992.0x000001

Effects of chemical in vitro activation versus fragmentation on human ovarian tissue and follicle growth in culture.

Authors: Hao, Jie, Li, Tianyi, Heinzelmann, Manuel, Moussaud-Lamodière, Elisabeth, Lebre, Filipa, Krjutškov, Kaarel, Damdimopoulos, Anastasios, Arnelo, Catarina, Pettersson, Karin, Alfaro-Moreno, Ernesto, Lindskog, Cecilia, Duursen, Majorie van, Damdimopoulou, Pauliina

Source: Human Reproduction Open; 2024, Vol. 2024 Issue 3, p1-17, 17p

Subject Terms: PTEN protein, PREMATURE ovarian failure, TISSUE culture, REGIONAL development, FALSE discovery rate, OVARIAN cancer

Pleomorphic Adenoma Gene 1 Is Needed For Timely Zygotic Genome Activation and Early Embryo Development

Authors: Madissoon, Elo, Damdimopoulos, Anastasios, Katayama, Shintaro, Krjutškov, Kaarel, Einarsdottir, Elisabet, Mamia, Katariina, De Groef, Bert, Hovatta, Outi, Kere, Juha, Damdimopoulou, Pauliina

Source: Scientific reports. 9(1):1-11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179715871.0x000001&indx=1&recIds=ETOCvdc_100179715871.0x000001

Intestinal stroma guides monocyte differentiation to macrophages through GM-CSF.

Authors: Kvedaraite, Egle, Lourda, Magda, Mouratidou, Natalia, Düking, Tim, Padhi, Avinash, Moll, Kirsten, Czarnewski, Paulo, Sinha, Indranil, Xagoraris, Ioanna, Kokkinou, Efthymia, Damdimopoulos, Anastasios, Weigel, Whitney, Hartwig, Olga, Santos, Telma E., Soini, Tea, Van Acker, Aline, Rahkonen, Nelly, Flodström Tullberg, Malin, Ringqvist, Emma, Buggert, Marcus

Source: Nature Communications; 2/27/2024, Vol. 15 Issue 1, p1-16, 16p

Subject Terms: MONOCYTES, INFLAMMATORY bowel diseases, GRANULOCYTE-macrophage colony-stimulating factor, MACROPHAGES, INTESTINES, STROMAL cells, HOMEOSTASIS

Pharmacological HIF‐PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation

Authors: Burmakin, Mikhail, Fasching, Angelica, Kobayashi, Hanako, Urrutia, Andrés A., Damdimopoulos, Anastasios, Palm, Fredrik, Haase, Volker H.

Source: Acta physiologica. 233(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128652548.0x000001&indx=1&recIds=ETOCvdc_100128652548.0x000001

Multi-omics analysis of the cervical epithelial integrity of women using depot medroxyprogesterone acetate.

Authors: Bradley, Frideborg¹, Franzén Boger, Mathias¹, Kaldhusdal, Vilde¹, Åhlberg, Alexandra¹, Edfeldt, Gabriella¹, Lajoie, Julie^2,3, Bergström, Sofia⁴, Omollo, Kenneth³, Damdimopoulos, Anastasios⁵, Czarnewski, Paulo⁶, Månberg, Anna⁴, Oyugi, Julius^2,3, Kimani, Joshua^2,3,7, Nilsson, Peter⁴, Fowke, Keith^2,3,7,8, Tjernlund, Annelie¹, Broliden, Kristina¹, kristina.broliden@ki.se

Source: PLoS Pathogens; 5/9/2022, Vol. 18 Issue 5, p1-29, 29p

Single-cell analysis of human ovarian cortex identifies distinct cell populations but no oogonial stem cells

Authors: Wagner, Magdalena, Yoshihara, Masahito, Douagi, Iyadh, Damdimopoulos, Anastasios, Panula, Sarita, Petropoulos, Sophie, Lu, Haojiang, Pettersson, Karin, Palm, Kerstin, Katayama, Shintaro, Hovatta, Outi, Kere, Juha, Lanner, Fredrik, Damdimopoulou, Pauliina

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100164251882.0x000001&indx=1&recIds=ETOCvdc_100164251882.0x000001

A Single Dose of Enterolactone Activates Estrogen Signaling and Regulates Expression of Circadian Clock Genes in Mice

Authors: Damdimopoulou, Pauliina ^*, Nurmi, Tarja, Salminen, Anu, Damdimopoulos, Anastasios E., Kotka, Maria, van der Saag, Paul, Strauss, Leena, Poutanen, Matti, Pongratz, Ingemar, Mäkelä, Sari

Source: In The Journal of Nutrition September 2011 141(9):1583-1589

The human thioredoxin reductase-1 splice variant TXNRD1_v3 is an atypical inducer of cytoplasmic filaments and cell membrane filopodia

Authors: Damdimopoulou, Pauliina E., Miranda-Vizuete, Antonio, Arnér, Elias S.J., Gustafsson, Jan-Åke, Damdimopoulos, Anastasios E.

Source: In BBA - Molecular Cell Research 2009 1793(10):1588-1596

Sex- and Female Age-Dependent Differences in Gene Expression in Diffuse Large B-Cell Lymphoma—Possible Estrogen Effects.

Authors: Huang, Dan, Berglund, Mattias, Damdimopoulos, Anastasios, Antonson, Per, Lindskog, Cecilia, Enblad, Gunilla, Amini, Rose-Marie, Okret, Sam

Source: Cancers; Feb2023, Vol. 15 Issue 4, p1298, 14p

Subject Terms: SEQUENCE analysis, AGE distribution, IMMUNOHISTOCHEMISTRY, B cell lymphoma, ESTROGEN, SEX distribution, GENE expression, POSTMENOPAUSE, RESEARCH funding