RNA helicases, DDX5 and DDX17, facilitate lytic reactivation of gammaherpesviruses.

Authors: Sandhu, Praneet Kaur^1,2 (AUTHOR), Damania, Blossom^1,2 (AUTHOR) blossom_damania@med.unc.edu

Source: PLoS Pathogens. 4/21/2025, Vol. 21 Issue 4, p1-32. 32p.

Subject Terms: *KAPOSI'S sarcoma-associated herpesvirus, *B cell lymphoma, *VIRAL proteins, *ONCOGENIC viruses, *VIRAL genes

Unraveling the Kaposi Sarcoma-Associated Herpesvirus (KSHV) Lifecycle: An Overview of Latency, Lytic Replication, and KSHV-Associated Diseases.

Authors: Losay, Victor A.^1,2 (AUTHOR), Damania, Blossom^1,2,3 (AUTHOR) damania@med.unc.edu

Source: Viruses (1999-4915). Feb2025, Vol. 17 Issue 2, p177. 33p.

Subject Terms: *KAPOSI'S sarcoma, *VIRAL genomes, *LYTIC cycle, *VIRAL genes, *VIRAL replication

Molecular Mechanisms of Kaposi Sarcoma-Associated Herpesvirus (HHV8)-Related Lymphomagenesis.

Authors: Yu, Caroline J.¹ (AUTHOR) cjyu@unc.edu, Damania, Blossom¹ (AUTHOR) damania@med.unc.edu

Source: Cancers. Nov2024, Vol. 16 Issue 21, p3693. 18p.

Subject Terms: *VIRAL proteins, *HERPESVIRUSES, *PLASMIDS, *KAPOSI'S sarcoma, *LYMPHOMAS, *CASTLEMAN'S disease, *LATENT infection, *GENE expression, *MOLECULAR biology, *LYMPHOPROLIFERATIVE disorders, *CELL survival, *CARCINOGENESIS, *B cells, *DISEASE progression, *GENOMES, *DISEASE complications

The complete Kaposi sarcoma-associated herpesvirus genome induces early-onset, metastatic angiosarcoma in transgenic mice

Authors: Sin, Sang-Hoon, Eason, Anthony B., Kim, Yongbaek, Schneider, Johann W., Damania, Blossom, Dittmer, Dirk P.

Source: In Cell Host & Microbe 8 May 2024 32(5):755-767

AGC kinase inhibitors regulate STING signaling through SGK-dependent and SGK-independent mechanisms

Authors: Castillo Cabrera, Johnny, Dang, Hong, Graves, Adam, Zhang, Zhigang, Torres-Castillo, Jose, Li, Kelin, King, Zayna, Liu, Pengda, Aubé, Jeff, Bear, James E., Damania, Blossom, Hagan, Robert S., Baldwin, Albert S.

Source: In Cell Chemical Biology 21 December 2023 30(12):1601-1616

Apoptotic caspases suppress an MDA5-driven IFN response during productive replication of human papillomavirus type 31

Authors: Huang, Ning, Groover, Des’ree, Damania, Blossom, Moody, Cary

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Jul . 119(29), 1-12.

Access URL: https://www.jstor.org/stable/27171845

Oncogenic viruses, cancer biology, and innate immunity

Authors: White, Maria C, Wu, Xinjun, Damania, Blossom

Source: In Current Opinion in Immunology October 2022 78

Epstein-Barr virus: Biology and clinical disease

Authors: Damania, Blossom, Kenney, Shannon C., Raab-Traub, Nancy

Source: In Cell 29 September 2022 185(20):3652-3670

Activation and Evasion of Innate Immunity by Gammaherpesviruses

Authors: Lange, Philip T., White, Maria C., Damania, Blossom

Source: In Journal of Molecular Biology 30 March 2022 434(6)

The regulation of KSHV lytic reactivation by viral and cellular factors

Authors: Sandhu, Praneet Kaur, Damania, Blossom

Source: In Current Opinion in Virology February 2022 52:39-47

Modulation of Cell Cycle Kinases by Kaposi's Sarcoma‐Associated Herpesvirus.

Authors: Longworth, Steven, Damania, Blossom

Source: Journal of Medical Virology; Jan2025, Vol. 97 Issue 1, p1-11, 11p

Subject Terms: HUMAN cell cycle, CELL division, CELL cycle, VIRAL genomes, DNA synthesis

Modeling oncogenic herpesvirus infections in humanized mice

Authors: Lange, Philip T, Damania, Blossom

Source: In Current Opinion in Virology October 2020 44:90-96

Streptavidin Promotes DNA Binding and Activation of cGAS to Enhance Innate Immunity

Authors: Zhang, Yanqiong, Ma, Zhe, Wang, Ying, Boyer, Joshua, Ni, Guoxin, Cheng, Liang, Su, Siyuan, Zhang, Zhigang, Zhu, Zhichuan, Qian, Jiayi, Su, Lishan, Zhang, Qi, Damania, Blossom, Liu, Pengda

Source: In iScience 25 September 2020 23(9)

Kinome profiling of non-Hodgkin lymphoma identifies Tyro3 as a therapeutic target in primary effusion lymphoma

Authors: Wong, Jason P., Stuhlmiller, Timothy J., Giffin, Louise C., Lin, Carolina, Bigi, Rachele, Zhao, Jichen, Zhang, Weihe, Cruz, Ariana G. Bravo, Park, Steven I., Earp, H. Shelton, Dittmer, Dirk P., Frye, Stephen V., Wang, Xiaodong, Johnson, Gary L., Damania, Blossom

Source: Proceedings of the National Academy of Sciences of the United States of America, 2019 Aug . 116(33), 16541-16550.

Access URL: https://www.jstor.org/stable/26850449

ADAR1 Facilitates KSHV Lytic Reactivation by Modulating the RLR-Dependent Signaling Pathway

Authors: Zhang, Huirong, Ni, Guoxin, Damania, Blossom

Source: In Cell Reports 28 April 2020 31(4)

Small molecule screening identifies inhibitors of the Epstein-Barr virus deubiquitinating enzyme, BPLF1

Authors: Atkins, Sage L., Motaib, Safiyyah, Wiser, Laura C., Hopcraft, Sharon E., Hardy, Paul B., Shackelford, Julia, Foote, Peter, Wade, Ashley H., Damania, Blossom, Pagano, Joseph S., Pearce, Kenneth H., Whitehurst, Christopher B.

Source: In Antiviral Research January 2020 173

Human DNA tumor viruses evade uracil-mediated antiviral immunity.

Authors: Stewart, Jessica A.¹ (AUTHOR), Damania, Blossom¹ (AUTHOR) damania@med.unc.edu

Source: PLoS Pathogens. 3/30/2023, Vol. 18 Issue 3, p1-9. 9p.

Subject Terms: *ONCOGENIC DNA viruses, *HUMAN DNA, *DNA mismatch repair, *DNA repair, *ONCOGENIC proteins, *NON-coding DNA, *DIHYDROPYRIMIDINE dehydrogenase

Apoptotic Caspases Suppress Expression of Endogenous Retroviruses in HPV31+ Cells That Are Associated with Activation of an Innate Immune Response.

Authors: Studstill, Caleb, Huang, Ning, Sundstrom, Shelby, Moscoso, Samantha, Zhang, Huirong, Damania, Blossom, Moody, Cary

Source: Viruses (1999-4915); Nov2024, Vol. 16 Issue 11, p1695, 14p

Subject Terms: LIFE cycles (Biology), HUMAN papillomavirus, ENDOGENOUS retroviruses, DOUBLE-stranded RNA, CELL differentiation

Kaposi's Sarcoma-Associated Herpesvirus Expresses an Array of Viral MicroRNAs in Latently Infected Cells

Authors: Cai, Xuezhong, Lu, Shihua, Zhang, Zhihong, Gonzalez, Carlos M., Damania, Blossom, Cullen, Bryan R., Roizman, Bernard

Source: Proceedings of the National Academy of Sciences of the United States of America, 2005 Apr 01. 102(15), 5570-5575.

Access URL: https://www.jstor.org/stable/3375090

Tumour viruses and innate immunity

Authors: Hopcraft, Sharon E., Damania, Blossom

Source: Philosophical Transactions: Biological Sciences, 2017 Oct . 372(1732), 1-9.

Access URL: https://www.jstor.org/stable/44679147