Preclinical study of engineering MSCs promoting diabetic wound healing and other inflammatory diseases through M2 polarization

Authors: Di Wu, Rencun Liu, Xiaotong Cen, Wanwen Dong, Qing Chen, Jiali Lin, Xia Wang, Yixia Ling, Rui Mao, Haitao Sun, Rui Huang, Huanxing Su, Hongjie Xu, Dajiang Qin

Source: Stem Cell Research & Therapy, Vol 16, Iss 1, Pp 1-22 (2025)

Subject Terms: Mesenchymal stem cells, Macrophage, Diabetic wound healing, Posttraumatic inflammation, Tissue repair, Regeneration, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/3dc53bce0a65401f8379a2408c718911

Impact of c-JUN deficiency on thalamus development in mice and human neural models

Authors: Jiantao Shi, Qing Chen, Jianheng Lai, Jieying Zhu, Ran Zhang, Md. Abdul Mazid, Dongwei Li, Huanxing Su, Dajiang Qin

Source: Cell & Bioscience, Vol 14, Iss 1, Pp 1-21 (2024)

Subject Terms: c-JUN, AP-1, NPC, Cerebral organoids, Thalamus organoids, Neural development, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2045-3701

Access URL: https://doaj.org/article/b913d2cffd2e422aa812e38c59950ec2

Endogenous retroviral ERVH48-1 promotes human urine cell reprogramming

Authors: Yuling Peng, Jieying Zhu, Qi Zhang, Ran Zhang, Zhenhua Wang, Zesen Ye, Ning Ma, Dajiang Qin, Duanqing Pei, Dongwei Li

Source: Cell Regeneration, Vol 13, Iss 1, Pp 1-15 (2024)

Subject Terms: Endogenous retroviruses, ERVH48-1, Human embryonic stem cells, Induced pluripotent stem cells, Urine cell integration-free reprogramming system, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2045-9769

Access URL: https://doaj.org/article/b45804db34c44fc8b80e56612c58a898

Case report: A novel third-generation anti-CD19/CD22 CAR T-cells combined with auto-HSCT for relapsed Burkitt lymphoma

Authors: Xiaodan Luo, Ao Chen, Le Qin, Robert Weinkove, Rong Zhao, Ting Ye, Sihui Chen, Jianli Tang, Jianbo Liu, Jiayu Huang, Boyun Shi, Danyun Yuan, Huo Tan, Dajiang Qin, Zhaoyang Tang, Peng Li, Runhui Zheng

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: relapsed/refractory Burkitt lymphoma, CAR T-cell therapy, autologous hematopoietic stem cell transplantation, CD19/CD22 dual target, immunotherapy, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1497736/full; https://doaj.org/toc/1664-3224

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Lycorine protects motor neurons against TDP-43 proteinopathy-induced degeneration in cross-species models with amyotrophic lateral sclerosis

Authors: Jing Wen, Yunhao Li, Yanzhu Qin, Lingli Yan, Ke Zhang, Ang Li, Ziying Wang, Feng Yu, Jianheng Lai, Wei Yang, Yong U. Liu, Dajiang Qin, Huanxing Su

Source: Pharmacological Research, Vol 210, Iss , Pp 107518- (2024)

Subject Terms: ALS, TDP-43 proteinopathy, Lycorine, UPS, Motor neurons, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1043661824004638; https://doaj.org/toc/1096-1186

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Chemical screen in zebrafish lateral line identified compounds that ameliorate neomycin-induced ototoxicity by inhibiting ferroptosis pathway

Authors: Yipu Fan, Yihan Zhang, Dajiang Qin, Xiaodong Shu

Source: Cell & Bioscience, Vol 14, Iss 1, Pp 1-16 (2024)

Subject Terms: Aminoglycoside, Neomycin, Ototoxicity, Ferroptosis, Zebrafish, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2045-3701

Access URL: https://doaj.org/article/37808a6963c246a6a15cabfe890f726d

Variability in SOD1-associated amyotrophic lateral sclerosis: geographic patterns, clinical heterogeneity, molecular alterations, and therapeutic implications

Authors: Miaodan Huang, Yong U. Liu, Xiaoli Yao, Dajiang Qin, Huanxing Su

Source: Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-19 (2024)

Subject Terms: Amyotrophic lateral sclerosis, SOD1 variants, Genotype, Geographic pattern, Genetic therapy, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9158

Access URL: https://doaj.org/article/cc72ef5b16f14117875ab7f4c7c43515

NAD+ dependent UPRmt activation underlies intestinal aging caused by mitochondrial DNA mutations

Authors: Liang Yang, Zifeng Ruan, Xiaobing Lin, Hao Wang, Yanmin Xin, Haite Tang, Zhijuan Hu, Yunhao Zhou, Yi Wu, Junwei Wang, Dajiang Qin, Gang Lu, Kerry M. Loomes, Wai-Yee Chan, Xingguo Liu

Source: Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/b31222b4952b4cd8aa803588340aa940

UBE2O ubiquitinates PTRF/CAVIN1 and inhibits the secretion of exosome-related PTRF/CAVIN1

Authors: Xiaotong Cen, Qing Chen, Bin Wang, Hongjie Xu, Xu Wang, Yixia Ling, Xiaofei Zhang, Dajiang Qin

Source: Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-17 (2022)

Subject Terms: Exosome secretion, PTRF/CAVIN1, SDPR/CAVIN2, UBE2O, Ubiquitination, Medicine, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/1478-811X

Access URL: https://doaj.org/article/4f651410127b4f9695987e687a120e28

Co-expression of a PD-L1-specific chimeric switch receptor augments the efficacy and persistence of CAR T cells via the CD70-CD27 axis

Authors: Le Qin, Yuanbin Cui, Tingjie Yuan, Dongmei Chen, Ruocong Zhao, Shanglin Li, Zhiwu Jiang, Qiting Wu, Youguo Long, Suna Wang, Zhaoyang Tang, Huixia Pan, Xiaoping Li, Wei Wei, Jie Yang, Xuequn Luo, Zhenfeng Zhang, Qiannan Tang, Pentao Liu, Robert Weinkove, Yao Yao, Dajiang Qin, Jean Paul Thiery, Peng Li

Source: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/d2342c54a2474b7a9866f95bebd32b0a

T lymphocytes expressing the switchable chimeric Fc receptor CD64 exhibit augmented persistence and antitumor activity

Authors: Yuanbin Cui, Tingjie Yuan, Ying Wang, Diwei Zheng, Le Qin, Shanglin Li, Zhiwu Jiang, Shouheng Lin, Wenjing Guo, Zhi Wang, Zhaoduan Liang, Yi Li, Yao Yao, Xingguo Liu, Qiannan Tang, Hai-Yan Tu, Xu-Chao Zhang, Zhaoyang Tang, Nathalie Wong, Zhenfeng Zhang, Dajiang Qin, Jean Paul Thiery, Kailin Xu, Peng Li

Source: Cell Reports, Vol 42, Iss 7, Pp 112797- (2023)

Subject Terms: CP: Cancer, CP: Immunology, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124723008082; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/19026a5a9b9f441696fdcf97f3be7fbe

Presenilin-1 F105C mutation leads to tau accumulation in human neurons via the Akt/mTORC1 signaling pathway

Authors: Cheong-Meng Chong, Yuan Tan, Jiaqi Tong, Minjing Ke, Ke Zhang, Lingli Yan, Xiaotong Cen, Jia-Hong Lu, Guobing Chen, Huanxing Su, Dajiang Qin

Source: Cell & Bioscience, Vol 12, Iss 1, Pp 1-15 (2022)

Subject Terms: mTOR, Presenilin-1, iPSC, CRISPR/Cas9, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2045-3701

Access URL: https://doaj.org/article/755c73d220034150b8ead9b0e7fa98f7

A hybrid hydrogel encapsulating human umbilical cord mesenchymal stem cells enhances diabetic wound healing

Authors: Hongjie Xu, Jingjing Wang, Di Wu, Dajiang Qin

Source: Journal of Materials Science: Materials in Medicine, Vol 33, Iss 8, Pp 1-14 (2022)

Subject Terms: Materials of engineering and construction. Mechanics of materials, TA401-492, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1573-4838

Access URL: https://doaj.org/article/88032bb342f5451b87689bbd71a53a57

DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling

Authors: Ke Zhang, Miaodan Huang, Ang Li, Jing Wen, Lingli Yan, Yunhao Li, Liman Guo, Kumaran Satyanarayanan Senthil, Yangyang Zhou, Guobing Chen, Yong Liu, Xiaofei Zhang, Xiaoli Yao, Dajiang Qin, Huanxing Su

Source: Cell Reports, Vol 42, Iss 1, Pp 111986- (2023)

Subject Terms: CP: Cell biology, Biology (General), QH301-705.5

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Relation: http://www.sciencedirect.com/science/article/pii/S2211124722018903; https://doaj.org/toc/2211-1247

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Human fetal mesenchymal stem cells secretome promotes scarless diabetic wound healing through heat‐shock protein family

Authors: Bin Wang, Mengru Pang, Yancheng Song, Haixing Wang, Pan Qi, Shanshan Bai, Xiaoxuan Lei, Shikun Wei, Zhixian Zong, Sien Lin, Xiaoting Zhang, Xiaotong Cen, Xia Wang, Yongkang Yang, Yuan Li, Yan Wang, Hongjie Xu, Lin Huang, Micky Tortorella, Biao Cheng, Yukwai Lee, Dajiang Qin, Gang Li

Source: Bioengineering & Translational Medicine, Vol 8, Iss 1, Pp n/a-n/a (2023)

Subject Terms: bioreactor, diabetic wound healing, fetal mesenchymal stem cell secretome, PLGA particles, quality control, Chemical engineering, TP155-156, Biotechnology, TP248.13-248.65, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2380-6761

Access URL: https://doaj.org/article/85a2e4d709184f659ddeb42b68003c2e

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation

Authors: Ruona Shi, Xue Shi, Dajiang Qin, Shibing Tang, Michiel Vermeulen, Xiaofei Zhang

Source: Cell & Bioscience, Vol 11, Iss 1, Pp 1-14 (2021)

Subject Terms: Linear ubiquitination, OTULIN, SNX27, NF-κB, Interaction, Localisation, Biotechnology, TP248.13-248.65, Biology (General), QH301-705.5, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/2045-3701

Access URL: https://doaj.org/article/979efb8a0d184232a27267a9a6efb10c

A superfine glass fibre air filter with rapid response to photocatalytic antibacterial properties under visible light by loading rGO/ZnO

Authors: Yongyi Luo, Fuqiang Zhai, Yingchun Zhang, Zhiqian Chen, Mingde Ding, Dajiang Qin, Jinming Yang, Guang Feng, Lu Li

Source: Royal Society Open Science, Vol 8, Iss 8 (2021)

Subject Terms: air filter, superfine glass fibre, photocatalyst, antibacterial, visible light, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2054-5703

Access URL: https://doaj.org/article/a872cbbb743743a2a37ee79119adfd56

Static Magnetic Fields Regulate T-Type Calcium Ion Channels and Mediate Mesenchymal Stem Cells Proliferation

Authors: Haokaifeng Wu, Chuang Li, Muqaddas Masood, Zhen Zhang, Esther González-Almela, Alvaro Castells-Garcia, Gaoyang Zou, Xiaoduo Xu, Luqin Wang, Guoqing Zhao, Shengyong Yu, Ping Zhu, Bo Wang, Dajiang Qin, Jing Liu

Source: Cells, Vol 11, Iss 15, p 2460 (2022)

Subject Terms: static magnetic field, mesenchymal stem cell, T-type calcium ion channel, MAPK signaling pathway, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/15/2460; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/acf6c97613e3415588a72786ca17278d

The Roles of H19 in Regulating Inflammation and Aging

Authors: Bin Wang, Chun Wai Suen, Haibin Ma, Yan Wang, Ling Kong, Dajiang Qin, Yuk Wai Wayne Lee, Gang Li

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: long non-coding RNA, H19, aging, inflammation, stress, signaling network, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2020.579687/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/7ee32a489dd14b6abef348efeb304ba7

Mitochondrial Dysfunctions Contribute to Hypertrophic Cardiomyopathy in Patient iPSC-Derived Cardiomyocytes with MT-RNR2 Mutation

Authors: Shishi Li, Huaye Pan, Chao Tan, Yaping Sun, Yanrui Song, Xuan Zhang, Wei Yang, Xuexiang Wang, Dan Li, Yu Dai, Qiang Ma, Chenming Xu, Xufen Zhu, Lijun Kang, Yong Fu, Xuejun Xu, Jing Shu, Naiming Zhou, Feng Han, Dajiang Qin, Wendong Huang, Zhong Liu, Qingfeng Yan

Source: Stem Cell Reports, Vol 10, Iss 3, Pp 808-821 (2018)

Subject Terms: Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213671118300390; https://doaj.org/toc/2213-6711

Access URL: https://doaj.org/article/8f4a7d491eda4d67a772ab38acd2b2cc