Ultra-processed foods and risk of declined renal function: a dose–response meta-analysis of 786,216 participants.

Authors: Hojjati Kermani, Mohammad Ali¹, Awlqadr, Farhang Hameed², Talebi, Sepide^3,4, Mehrabani, Sanaz⁵, Ghoreishy, Seyed Mojtaba^6,7, Wong, Alexei⁸, Amirian, Parsa⁹, Zarpoosh, Mahsa⁹, Moradi, Sajjad^10,11, sajadmoradi9096@gmail.com

Source: Journal of Health, Population & Nutrition; 3/18/2025, Vol. 44 Issue 1, p1-13, 13p

Estimating Earphone Level and Dose Using Real-Ear Measures and Ecological Momentary Assessment.

Authors: Jorgensen, Erik¹, erik.jorgensen@wisc.edu, Reynolds, Isabelle², Saxena, Trisha¹, Thomas, Marisa¹, Werner, Megan¹

Source: American Journal of Audiology; Mar2025, Vol. 34 Issue 1, p211-219, 9p

Ototoxic Drug Exposure and Hearing Loss in Neonates: A Scoping Review.

Authors: Rameshsankar, Subaasri¹, Seethapathy, Jayashree², jayashrees@sriramachandra.edu.in, Balakrishnan, Umamaheshwari³

Source: American Journal of Audiology; Dec2024, Vol. 33 Issue 4, p1356-1377, 22p

The Conflict between Regulatory Agencies over the 20,000-Fold Lowering of the Tolerable Daily Intake (TDI) for Bisphenol A (BPA) by the European Food Safety Authority (EFSA).

Authors: vom Saal, Frederick S.¹ vomsaalf@missouri.edu, Antoniou, Michael², Belcher, Scott M.³, Bergman, Ake⁴, Bhandari, Ramji K.¹, Birnbaum, Linda S.^5,6, Cohen, Aly⁷, Collins, Terrence J.⁸, Demeneix, Barbara⁹, Fine, Anne Marie¹⁰, Flaws, Jodi A.¹¹, Gayrard, Veronique¹², Goodson III, William H.¹³, Gore, Andrea C.¹⁴, Heindel, Jerrold J.¹⁵, Hunt, Patricia A.¹⁶, Taisen Iguchi¹⁷, Kassotis, Christopher D.^18,19, Kortenkamp, Andreas²⁰, Mesnage, Robin²

Source: Environmental Health Perspectives. Apr2024, Vol. 132 Issue 4, p045001-1-045001-16. 16p.

Subject Terms: *Environmental health, *Food consumption, *Hazardous substance release, *Food safety, *Phenols, *Environmental exposure, *Endocrine disruptors, Food contamination prevention, Risk assessment, Government agencies, Body weight, Dose-effect relationship in pharmacology, Government regulation

Geographic Terms: Germany

Company/Entity: United States. Food & Drug Administration

The Effect of Chia Seed on Blood Pressure, Body Composition, and Glycemic Control: A GRADE-Assessed Systematic Review and Dose-Response Meta-Analysis of Randomized Controlled Trials.

Authors: TaghipourSheshdeh, Faranak¹, Behzadi, Mehrdad¹, Bashiri, Sara¹, Mohammadi-Sartang, Mohsen²

Source: Nutrition Reviews; Mar2025, Vol. 83 Issue 3, p448-465, 18p

Folate Biomarkers, Folate Intake, and Risk of Death From All Causes, Cardiovascular Disease, and Cancer: A Systematic Review and Dose-Response Meta-Analysis of Prospective Cohort Studies.

Authors: Fallah, Melika¹, Dehnavi, Maryam Karim^1,2, Lotfi, Keyhan^1,2, Aminianfar, Azadeh³, Azadbakht, Leila^1,4, Esmaillzadeh, Ahmad^1,5,6

Source: Nutrition Reviews; Mar2025, Vol. 83 Issue 3, pe801-e813, 13p

Dose-effect relationship of copolymer on enhancing aqueous lubrication of a hybrid osteoarthritis drug delivery nanocarrier.

Authors: Tian, Lejie¹ (AUTHOR), Han, Sirui¹ (AUTHOR), Wu, Wei¹ (AUTHOR), Li, Zhihuan¹ (AUTHOR), He, Zhengze¹ (AUTHOR), Liu, Chen¹ (AUTHOR), Xue, Huidan² (AUTHOR), Zhou, Feng³ (AUTHOR), Liu, Weimin^1,3 (AUTHOR), Liu, Jianxi¹ (AUTHOR) jianxiliu@nwpu.edu.cn

Source: Journal of Colloid & Interface Science. Feb2025:Part B, Vol. 679, p788-797. 10p.

Subject Terms: *DOSE-effect relationship in pharmacology, *ETHYLENE glycol, *TRANSITION temperature, *METAL-organic frameworks, *ANTI-inflammatory agents, *THERMORESPONSIVE polymers

Dietary Magnesium Intake in Relation to Depression in Adults: A GRADE-Assessed Systematic Review and Dose–Response Meta-analysis of Epidemiologic Studies.

Authors: Hajhashemy, Zahra^1,2, Shirani, Fatemeh³, Askari, Gholamreza²

Source: Nutrition Reviews; Feb2025, Vol. 83 Issue 2, p217-229, 13p

Thylakoid supplementation and hunger and fullness perception: a systematic review and dose-response meta-analysis of randomized controlled trials.

Authors: Nikrad, Negin¹, Sarghein, Mehdi Ghaffari¹, Farhangi, Mahdieh Abbasalizad²

Source: Nutrition Reviews; Feb2025, Vol. 83 Issue 2, pe42-e53, 12p

HTSplotter: An end-to-end data processing, analysis and visualisation tool for chemical and genetic in vitro perturbation screening.

Authors: Nunes, Carolina^1,2,3,4 (AUTHOR), Anckaert, Jasper^3,5 (AUTHOR), De Vloed, Fanny^2,3 (AUTHOR), De Wyn, Jolien^2,3 (AUTHOR), Durinck, Kaat^2,3 (AUTHOR), Vandesompele, Jo^3,5 (AUTHOR), Speleman, Frank^2,3 (AUTHOR), Vermeirssen, Vanessa^1,2,3,4 (AUTHOR) vanessa.vermeirssen@ugent.be

Source: PLoS ONE. 1/5/2024, Vol. 19 Issue 1, p1-19. 19p.

Subject Terms: *DOSE-effect relationship in pharmacology, *ELECTRONIC data processing, *DRUG synergism, *PYTHON programming language, *HIGH throughput screening (Drug development), *PDF (Computer file format), *TEXT files

Exploring Route-Specific Pharmacokinetics of PFAS in Mice by Coupling in Vivo Tests and Physiologically Based Toxicokinetic Models.

Authors: Yumin Zhu¹, Xiaoyu Pan², Yibo Jia¹, Xin Yang¹, Xiaohua Song¹, Jiaqi Ding¹, Wenjue Zhong¹, Jianfeng Feng¹, Lingyan Zhu¹ zhuly@nankai.edu.cn

Source: Environmental Health Perspectives. Dec2023, Vol. 131 Issue 12, p127012-1-127012-13. 13p.

Subject Terms: *Bioavailability, *Animal experimentation, *Fluorocarbons, *Toxicity testing, *Environmental exposure, Biological models, In vivo studies, Oral drug administration, Calibration, Regression analysis, Dose-effect relationship in pharmacology, Descriptive statistics, Research funding, Inhalation administration, Cutaneous therapeutics, Data analysis software, Mice

Quantitative Integration of Mode of Action Information in Dose-Response Modeling and POD Estimation for Nonmutagenic Carcinogens: A Case Study of TCDD.

Authors: Qiran Chen¹, Yun Zhou², Chao Ji², Klaunig, James E.², Kan Shao² kshao@indiana.edu

Source: Environmental Health Perspectives. Dec2023, Vol. 131 Issue 12, p127022-1-127022-11. 11p.

Subject Terms: *Carcinogens, *Animal experimentation, *Dioxins, Liver tumors, In vivo studies, Antineoplastic agents, Risk assessment, Conceptual structures, Rats, Dose-effect relationship in pharmacology, Tumors, Data analysis software

What is NAD+?

Authors: Gonzalez, Gary

Source: Life Extension. May2025, Vol. 31 Issue 5, p1-5. 5p.

Subjects: CELL physiology, GERIATRICS, VITAMIN B complex, DOSE-effect relationship in pharmacology, COGNITION disorders, ACTIVE aging, COENZYMES, LONGEVITY, METABOLISM

Hospitalization and Mortality for Insured Patients in the United States with COVID-19 with and without Autism Spectrum Disorder.

Authors: Davis, Amber^1,2, Van Eck, Kathryn^2,3,4, Copeland-Linder, Nikeea^2,3,4, Phuong, Karen⁵, Belcher, Harolyn M.E.^1,2,4, Belcher@kennedykrieger.org

Source: Journal of Autism & Developmental Disorders; Jun2024, Vol. 54 Issue 6, p2347-2354, 8p

Targeted randomization dose optimization trials enable fractional dosing of scarce drugs.

Authors: Boonstra, Philip S.^1,2 (AUTHOR), Tabarrok, Alex³ (AUTHOR), Strohbehn, Garth W.^2,4,5,6,7 (AUTHOR) gstrohbe@umich.edu

Source: PLoS ONE. 10/30/2023, Vol. 18 Issue 10, p1-16. 16p.

Subject Terms: *DOSE-effect relationship in pharmacology, *DRUG efficacy, *DRUG development

Strategy for Designing In Vivo Dose–Response Comparison Studies.

Authors: Novick, Steven¹ (AUTHOR) steven.novick@takeda.com, Zhang, Tianhui¹ (AUTHOR)

Source: Pharmaceutical Statistics. Jan/Feb2025, Vol. 24 Issue 1, p1-16. 16p.

Subject Terms: *IN vivo studies, *DOSE-effect relationship in pharmacology, *SAMPLE size (Statistics), *STATISTICAL power analysis, *TREATMENT effectiveness, *DRUG discovery

Prolonged use of chlormadinone acetate and risk of intracranial meningioma: A population‐based cohort study.

Authors: Roland, Noémie¹ (AUTHOR) noemie.roland@assurance‐maladie.fr, Nguyen, Pierre¹ (AUTHOR), Neumann, Anke¹ (AUTHOR), Hoisnard, Léa² (AUTHOR), Passeri, Thibault³ (AUTHOR), Duranteau, Lise⁴ (AUTHOR), Coste, Joël^5,6 (AUTHOR), Froelich, Sébastien³ (AUTHOR), Zureik, Mahmoud^1,7 (AUTHOR), Weill, Alain¹ (AUTHOR)

Source: European Journal of Neurology. Jan2025, Vol. 32 Issue 1, p1-6. 6p.

Subject Terms: *DOSE-effect relationship in pharmacology, *MENINGIOMA, *COHORT analysis, *RISK assessment, *WOMEN'S health, *CONTRACEPTIVE drugs, *PROGESTATIONAL hormones

Applying two approaches to detect unmeasured confounding due to time-varying variables in a self-controlled risk interval design evaluating COVID-19 vaccine safety signals, using myocarditis as a case example.

Authors: Bots, Sophie H¹, Belitser, Svetlana¹, Groenwold, Rolf H H², Durán, Carlos E³, Riera-Arnau, Judit^3,4, Schultze, Anna⁵, Messina, Davide⁶, Segundo, Elena⁷, Douglas, Ian⁵, Carreras, Juan José⁸, Garcia-Poza, Patricia⁹, Gini, Rosa⁶, Huerta, Consuelo⁹, Martín-Pérez, Mar⁹, Martin, Ivonne³, Paoletti, Olga⁶, Bissacco, Carlo Alberto⁷, Correcher-Martínez, Elisa⁸, Souverein, Patrick¹, Urchueguía-Fornes, Arantxa⁸

Source: American Journal of Epidemiology; Jan2025, Vol. 194 Issue 1, p208-219, 12p

The impact of different strategies for modeling associations between medications at low doses and health outcomes: a simulation study and practical application to postpartum opioid use.

Authors: Spieker, Andrew J¹, Adgent, Margaret A², Osmundson, Sarah S³, Phillips, Sharon E¹, Mitchel Jr, Ed², Leech, Ashley A², Grijalva, Carlos G^2,4, Wiese, Andrew D²

Source: American Journal of Epidemiology; Jan2025, Vol. 194 Issue 1, p278-286, 9p

FDA changes buprenorphine labeling to favor higher doses.

Authors: Knopf, Alison

Source: Alcoholism & Drug Abuse Weekly. 1/13/2025, Vol. 37 Issue 2, p1-3. 3p.

Subjects: SUBSTANCE abuse, UNITED States. Food & Drug Administration, INFORMATION resources, DECISION making, DOSE-effect relationship in pharmacology, PATIENT-centered care, OPIOID analgesics, BUPRENORPHINE, DRUG labeling, UNITED States. Substance Abuse & Mental Health Services Administration

Geographic Terms: UNITED StatesReport Available