Pharmacological inhibition of PDGF-C/neuropilin-1 interaction: A novel strategy to reduce melanoma metastatic potential

Authors: Ceci, Claudia, Ruffini, Federica, Falconi, Mattia, Atzori, Maria Grazia, Falzon, Andrea, Lozzi, Flavia, Iacovelli, Federico, D’Atri, Stefania, Graziani, Grazia, Lacal, Pedro Miguel

Source: In Biomedicine & Pharmacotherapy July 2024 176

Targeting of PDGF-C/NRP-1 autocrine loop as a new strategy for counteracting the invasiveness of melanoma resistant to braf inhibitors

Authors: Ruffini, Federica, Ceci, Claudia, Atzori, Maria Grazia, Caporali, Simona, Levati, Lauretta, Bonmassar, Laura, Cappellini, Gian Carlo Antonini, D’Atri, Stefania, Graziani, Grazia, Lacal, Pedro Miguel

Source: In Pharmacological Research June 2023 192

Genetically Driven CD39 Expression Affects Sezary Cell Viability and IL-2 Production and Detects Two Patient Subsets with Distinct Prognosis

Authors: Picozza, Mario, Cristofoletti, Cristina, Bresin, Antonella, Fioretti, Martina, Sambucci, Manolo, Scala, Enrico, Monopoli, Alessandro, Cantonetti, Maria, Pilla, Maria Antonietta, Accetturi, Maria Pina, Borsellino, Giovanna, D’Atri, Stefania, Caprini, Elisabetta, Russo, Giandomenico, Narducci, Maria Grazia

Source: In Journal of Investigative Dermatology November 2022 142(11):3009-3019

Targeting the vascular endothelial growth factor receptor-1 by the monoclonal antibody D16F7 to increase the activity of immune checkpoint inhibitors against cutaneous melanoma

Authors: Lacal, Pedro Miguel, Atzori, Maria Grazia, Ruffini, Federica, Scimeca, Manuel, Bonanno, Elena, Cicconi, Rosella, Mattei, Maurizio, Bernardini, Roberta, D’Atri, Stefania, Tentori, Lucio, Graziani, Grazia ^*

Source: In Pharmacological Research September 2020 159

Shedding light on the interaction of polydatin and resveratrol with G-quadruplex and duplex DNA: a biophysical, computational and biological approach

Authors: Platella, Chiara, Raucci, Umberto, Rega, Nadia, D'Atri, Stefania, Levati, Lauretta, Roviello, Giovanni N., Fuggetta, Maria Pia, Musumeci, Domenica, Montesarchio, Daniela

Source: In International Journal of Biological Macromolecules 15 May 2020 151:1163-1172

Tolerance of Human MSH2 +/- Lymphoblastoid Cells to the Methylating Agent Temozolomide

Authors: Marra, Giancarlo, D'Atri, Stefania, Corti, Chantal, Bonmassar, Laura, Cattaruzza, Maria Sofia, Schweizer, Pascal, Heinimann, Karl, Bartosova, Zdena, Nyström-Lahti, Minna, Jiricny, Josef

Source: Proceedings of the National Academy of Sciences of the United States of America, 2001 Jun . 98(13), 7164-7169.

Access URL: https://www.jstor.org/stable/3055960

Circulating interleukin-8 and osteopontin are promising biomarkers of clinical outcomes in advanced melanoma patients treated with targeted therapy.

Authors: Levati, Lauretta, Tabolacci, Claudio, Facchiano, Antonio, Facchiano, Francesco, Alvino, Ester, Antonini Cappellini, Gian Carlo, Scala, Enrico, Bonmassar, Laura, Caporali, Simona, Lacal, Pedro Miguel, Bresin, Antonella, De Galitiis, Federica, Russo, Giandomenico, D'Atri, Stefania

Source: Journal of Experimental & Clinical Cancer Research (17569966); 8/15/2024, Vol. 43 Issue 1, p1-19, 19p

Subject Terms: PROPORTIONAL hazards models, PROGRESSION-free survival, CANCER prognosis, RECEIVER operating characteristic curves, OVERALL survival

Downregulation of 14-3-3σ Prevents Clonal Evolution and Leads to Immortalization of Primary Human Keratinocytes

Authors: Dellambra, Elena, Golisano, Osvaldo, Bondanza, Sergio, Siviero, Emanuela, Lacal, Pedro, Molinari, Marta, D'Atri, Stefania, de Luca, Michele

Source: The Journal of Cell Biology, 2000 May . 149(5), 1117-1129.

Access URL: https://www.jstor.org/stable/1619964

Correction to: Comprehensive genomic profiling on metastatic Melanoma: results from a network screening from 7 Italian Cancer Centres.

Authors: Pallocca, Matteo, Molineris, Ivan, Berrino, Enrico, Marcozzi, Benedetta, Betti, Martina, Levati, Lauretta, D'Atri, Stefania, Menin, Chiara, Madonna, Gabriele, Ghiorzo, Paola, Bulgarelli, Jenny, Ferraresi, Virgina, Venesio, Tiziana, Rodolfo, Monica, Rivoltini, Licia, Lanfrancone, Luisa, Ascierto, Paolo Antonio, Mazzarella, Luca, Pelicci, Pier Giuseppe, De Maria, Ruggero

Source: Journal of Translational Medicine; 10/22/2024, Vol. 22 Issue 1, p1-3, 3p

Subject Terms: MOLECULAR oncology, MEDICAL specialties & specialists, LIFE sciences, INTERNAL medicine, CANCER genetics

The potential impact of dietary choices on melanoma risk: an anti-inflammatory diet.

Authors: Fortes, Cristina, Mastroeni, Simona, Levati, Lauretta, Alotto, Massimo, Ricci, Francesco, D'Atri, Stefania

Source: Genes & Nutrition; 5/23/2024, Vol. 19 Issue 1, p1-8, 8p

Genomic Classification of Cutaneous Melanoma

Authors: Akbani, Rehan, Akdemir, Kadir C., Aksoy, B. Arman, Albert, Monique, Ally, Adrian, Amin, Samirkumar B., Arachchi, Harindra, Arora, Arshi, Auman, J. Todd, Ayala, Brenda, Baboud, Julien, Balasundaram, Miruna, Balu, Saianand, Barnabas, Nandita, Bartlett, John, Bartlett, Pam, Bastian, Boris C., Baylin, Stephen B., Behera, Madhusmita, Belyaev, Dmitry, Benz, Christopher, Bernard, Brady, Beroukhim, Rameen, Bir, Natalie, Black, Aaron D., Bodenheimer, Tom, Boice, Lori, Boland, Genevieve M., Bono, Riccardo, Bootwalla, Moiz S., Bosenberg, Marcus, Bowen, Jay, Bowlby, Reanne, Bristow, Christopher A., Brockway-Lunardi, Laura, Brooks, Denise, Brzezinski, Jakub, Bshara, Wiam, Buda, Elizabeth, Burns, William R., Butterfield, Yaron S.N., Button, Michael, Calderone, Tiffany, Cappellini, Giancarlo Antonini, Carter, Candace, Carter, Scott L., Cherney, Lynn, Cherniack, Andrew D., Chevalier, Aaron, Chin, Lynda, Cho, Juok, Cho, Raymond J., Choi, Yoon-La, Chu, Andy, Chudamani, Sudha, Cibulskis, Kristian, Ciriello, Giovanni, Clarke, Amanda, Coons, Stephen, Cope, Leslie, Crain, Daniel, Curley, Erin, Danilova, Ludmila, D’Atri, Stefania, Davidsen, Tanja, Davies, Michael A., Delman, Keith A., Demchok, John A., Deng, Qixia A., Deribe, Yonathan Lissanu, Dhalla, Noreen, Dhir, Rajiv, DiCara, Daniel, Dinikin, Michael, Dubina, Michael, Ebrom, J. Stephen, Egea, Sophie, Eley, Greg, Engel, Jay, Eschbacher, Jennifer M., Fedosenko, Konstantin V., Felau, Ina, Fennell, Timothy, Ferguson, Martin L., Fisher, Sheila, Flaherty, Keith T., Frazer, Scott, Frick, Jessica, Fulidou, Victoria, Gabriel, Stacey B., Gao, Jianjiong, Gardner, Johanna, Garraway, Levi A., Gastier-Foster, Julie M., Gaudioso, Carmelo, Gehlenborg, Nils, Genovese, Giannicola, Gerken, Mark, Gershenwald, Jeffrey E., Getz, Gad, Gomez-Fernandez, Carmen, Gribbin, Thomas, Grimsby, Jonna, Gross, Benjamin, Guin, Ranabir, Gutschner, Tony, Hadjipanayis, Angela, Halaban, Ruth, Hanf, Benjamin, Haussler, David, Haydu, Lauren E., Hayes, D. Neil, Hayward, Nicholas K., Heiman, David I., Herbert, Lynn, Herman, James G., Hersey, Peter, Hoadley, Katherine A., Hodis, Eran, Holt, Robert A., Hoon, Dave SB., Hoppough, Susan, Hoyle, Alan P., Huang, Franklin W., Huang, Mei, Huang, Sharon, Hutter, Carolyn M., Ibbs, Matthew, Iype, Lisa, Jacobsen, Anders, Jakrot, Valerie, Janning, Alyssa, Jeck, William R., Jefferys, Stuart R., Jensen, Mark A., Jones, Corbin D., Jones, Steven J.M., Ju, Zhenlin, Kakavand, Hojabr, Kang, Hyojin, Kefford, Richard F., Khuri, Fadlo R., Kim, Jaegil, Kirkwood, John M., Klode, Joachim, Korkut, Anil, Korski, Konstanty, Krauthammer, Michael, Kucherlapati, Raju, Kwong, Lawrence N., Kycler, Witold, Ladanyi, Marc, Lai, Phillip H., Laird, Peter W., Lander, Eric, Lawrence, Michael S., Lazar, Alexander J., Łaźniak, Radoslaw, Lee, Darlene, Lee, Jeffrey E., Lee, Junehawk, Lee, Kenneth, Lee, Semin, Lee, William, Leporowska, Ewa, Leraas, Kristen M., Li, Haiyan I., Lichtenberg, Tara M., Lichtenstein, Lee, Lin, Pei, Ling, Shiyun, Liu, Jia, Liu, Ouida, Liu, Wenbin, Long, Georgina V., Lu, Yiling, Ma, Singer, Ma, Yussanne, Mackiewicz, Andrzej, Mahadeshwar, Harshad S., Malke, Jared, Mallery, David, Manikhas, Georgy M., Mann, Graham J., Marra, Marco A., Matejka, Brenna, Mayo, Michael, Mehrabi, Sousan, Meng, Shaowu, Meyerson, Matthew, Mieczkowski, Piotr A., Miller, John P., Miller, Martin L., Mills, Gordon B., Moiseenko, Fedor, Moore, Richard A., Morris, Scott, Morrison, Carl, Morton, Donald, Moschos, Stergios, Mose, Lisle E., Muller, Florian L., Mungall, Andrew J., Murawa, Dawid, Murawa, Pawel, Murray, Bradley A., Nezi, Luigi, Ng, Sam, Nicholson, Dana, Noble, Michael S., Osunkoya, Adeboye, Owonikoko, Taofeek K., Ozenberger, Bradley A., Pagani, Elena, Paklina, Oxana V., Pantazi, Angeliki, Parfenov, Michael, Parfitt, Jeremy, Park, Peter J., Park, Woong-Yang, Parker, Joel S., Passarelli, Francesca, Penny, Robert, Perou, Charles M., Pihl, Todd D., Potapova, Olga, Prieto, Victor G., Protopopov, Alexei, Quinn, Michael J., Radenbaugh, Amie, Rai, Kunal, Ramalingam, Suresh S., Raman, Ayush T., Ramirez, Nilsa C., Ramirez, Ricardo, Rao, Uma, Rathmell, W. Kimryn, Ren, Xiaojia, Reynolds, Sheila M., Roach, Jeffrey, Robertson, A. Gordon, Ross, Merrick I., Roszik, Jason, Russo, Giandomenico, Saksena, Gordon, Saller, Charles, Samuels, Yardena, Sander, Chris, Sander, Cindy, Sandusky, George, Santoso, Netty, Saul, Melissa, Saw, Robyn PM., Schadendorf, Dirk, Schein, Jacqueline E., Schultz, Nikolaus, Schumacher, Steven E., Schwallier, Charles, Scolyer, Richard A., Seidman, Jonathan, Sekhar, Pedamallu Chandra, Sekhon, Harmanjatinder S., Senbabaoglu, Yasin, Seth, Sahil, Shannon, Kerwin F., Sharpe, Samantha, Sharpless, Norman E., Shaw, Kenna R. Mills, Shelton, Candace, Shelton, Troy, Shen, Ronglai, Sheth, Margi, Shi, Yan, Shiau, Carolyn J., Shmulevich, Ilya, Sica, Gabriel L., Simons, Janae V., Sinha, Rileen, Sipahimalani, Payal, Sofia, Heidi J., Soloway, Matthew G., Song, Xingzhi, Sougnez, Carrie, Spillane, Andrew J., Spychała, Arkadiusz, Stretch, Jonathan R., Stuart, Joshua, Suchorska, Wiktoria M., Sucker, Antje, Sumer, S. Onur, Sun, Yichao, Synott, Maria, Tabak, Barbara, Tabler, Teresa R., Tam, Angela, Tan, Donghui, Tang, Jiabin, Tarnuzzer, Roy, Tarvin, Katherine, Tatka, Honorata, Taylor, Barry S., Teresiak, Marek, Thiessen, Nina, Thompson, John F., Thorne, Leigh, Thorsson, Vesteinn, Trent, Jeffrey M., Triche, Timothy J., Jr., Tsai, Kenneth Y., Tsou, Peiling, Van Den Berg, David J., Van Allen, Eliezer M., Veluvolu, Umadevi, Verhaak, Roeland G., Voet, Douglas, Voronina, Olga, Walter, Vonn, Walton, Jessica S., Wan, Yunhu, Wang, Yuling, Wang, Zhining, Waring, Scot, Watson, Ian R., Weinhold, Nils, Weinstein, John N., Weisenberger, Daniel J., White, Peter, Wilkerson, Matthew D., Wilmott, James S., Wise, Lisa, Wiznerowicz, Maciej, Woodman, Scott E., Wu, Chang-Jiun, Wu, Chia-Chin, Wu, Junyuan, Wu, Ye, Xi, Ruibin, Xu, Andrew Wei, Yang, Da, Yang, Liming, Yang, Lixing, Zack, Travis I., Zenklusen, Jean C., Zhang, Hailei, Zhang, Jianhua, Zhang, Wei, Zhao, Xiaobei, Zhu, Jingchun, Zhu, Kelsey, Zimmer, Lisa, Zmuda, Erik, Zou, Lihua

Source: In Cell 18 June 2015 161(7):1681-1696

Comprehensive genomic profiling on metastatic Melanoma: results from a network screening from 7 Italian Cancer Centres.

Authors: Pallocca, Matteo, Molineris, Ivan, Berrino, Enrico, Marcozzi, Benedetta, Betti, Martina, Levati, Lauretta, D'Atri, Stefania, Menin, Chiara, Madonna, Gabriele, Ghiorzo, Paola, Bulgarelli, Jenny, Ferraresi, Virgina, Venesio, Tiziana, Rodolfo, Monica, Rivoltini, Licia, Lanfrancone, Luisa, Ascierto, Paolo Antonio, Mazzarella, Luca, Pelicci, Pier Giuseppe, De Maria, Ruggero

Source: Journal of Translational Medicine; 1/6/2024, Vol. 22 Issue 1, p1-7, 7p

Subject Terms: MACHINE learning, SINGLE nucleotide polymorphisms, MEDICAL screening, MELANOMA, RANDOM forest algorithms, PROGRESSION-free survival

Reversing vemurafenib‐resistance in primary melanoma cells by combined romidepsin and type I IFN treatment through blocking of tumorigenic signals and induction of immunogenic effects.

Authors: Fragale, Alessandra, Stellacci, Emilia, Romagnoli, Giulia, Licursi, Valerio, Parlato, Stefania, Canini, Irene, Remedi, Giacomo, Buoncervello, Maria, Matarrese, Paola, Pedace, Lucia, Ascione, Barbara, Pizzi, Simone, Tartaglia, Marco, D'Atri, Stefania, Presutti, Carlo, Capone, Imerio, Gabriele, Lucia

Source: International Journal of Cancer; Sep2023, Vol. 153 Issue 5, p1080-1095, 16p

Subject Terms: IPILIMUMAB, MICROPHTHALMIA-associated transcription factor, MELANOMA, IMMUNE checkpoint inhibitors, DNA fingerprinting, IMMUNE checkpoint proteins, DENDRITIC cells

Company/Entity: UNITED States. Food & Drug Administration

Down-regulation of the PTTG1 proto-oncogene contributes to the melanoma suppressive effects of the cyclin-dependent kinase inhibitor PHA-848125

Authors: Caporali, Simona, Alvino, Ester, Levati, Lauretta, Esposito, Alessia I., Ciomei, Marina, Brasca, Maria G., Del Bufalo, Donatella, Desideri, Marianna, Bonmassar, Enzo, Pfeffer, Ulrich, D’Atri, Stefania

Source: In Biochemical Pharmacology 1 September 2012 84(5):598-611

AKT Is Activated in an Ataxia-Telangiectasia and Rad3-Related-Dependent Manner in Response to Temozolomide and Confers Protection against Drug-Induced Cell Growth Inhibition

Authors: Caporali, Simona, Levati, Lauretta, Starace, Giuseppe, Ragone, Gianluca, Bonmassar, Enzo, Alvino, Ester, D’Atri, Stefania ^*

Source: In Molecular Pharmacology July 2008 74(1):173-183

A proangiogenic peptide derived from vascular endothelial growth factor receptor-1 acts through α5β1 integrin

Authors: Soro, Simonetta, Orecchia, Angela, Morbidelli, Lucia, Lacal, Pedro Miguel, Morea, Veronica, Ballmer-Hofer, Kurt, Ruffini, Federica, Ziche, Marina, D'Atri, Stefania, Zambruno, Giovanna, Tramontano, Anna, Failla, Cristina Maria

Source: In Blood 1 April 2008 111(7):3479-3488

Inhibition of endothelial cell migration and angiogenesis by a vascular endothelial growth factor receptor-1 derived peptide

Authors: Lacal, Pedro M., Morea, Veronica, Ruffini, Federica, Orecchia, Angela, Dorio, Annalisa S., Failla, Cristina M., Soro, Simonetta, Tentori, Lucio, Zambruno, Giovanna, Graziani, Grazia, Tramontano, Anna, D’Atri, Stefania

Source: In European Journal of Cancer 2008 44(13):1914-1921

BCG-infected adherent mononuclear cells release cytokines that regulate group 1 CD1 molecule expression

Authors: Prete, Salvatore Pasquale, Giuliani, Anna, D'Atri, Stefania, Graziani, Grazia, Balduzzi, Alessandra, Oggioni, Marco Rinaldo, Iona, Elisabetta, Girolomoni, Giampiero, Bonmassar, Laura, Romani, Luigina, Franzese, Ornella

Source: In International Immunopharmacology March 2007 7(3):321-332

Novel role of triazenes in haematological malignancies: Pilot study of Temozolomide, Lomeguatrib and IL-2 in the chemo-immunotherapy of acute leukaemia

Authors: Caporaso, Patrizia, Turriziani, Mario, Venditti, Adriano, Marchesi, Francesco, Buccisano, Francesco, Tirindelli, Maria Cristina, Alvino, Ester, Garbin, Alberto, Tortorelli, Grazia, Toppo, Laura, Bonmassar, Enzo, D’Atri, Stefania, Amadori, Sergio

Source: In DNA Repair 2007 6(8):1179-1186

Peptide derived from vascular endothelial growth factor receptor-1 binding integrin α5β1 having proangiogenic activity