PIM kinase inhibitor AZD1208 in conjunction with Th1 cytokines potentiate death of breast cancer cells in vitro while also maximizing suppression of tumor growth in vivo when combined with immunotherapy

Authors: Anwar, Ariel, Lepore, Carissa, Czerniecki, Brian J., Koski, Gary K., Showalter, Loral E.

Source: In Cellular Immunology March-April 2024 397-398

Reviewing the significance of dendritic cell vaccines in interrupting breast cancer development

Authors: Gautam, Namrata, Ramamoorthi, Ganesan, Champion, Nicholas, Han, Hyo S., Czerniecki, Brian J.

Source: In Molecular Aspects of Medicine February 2024 95

Phase 2 Study of Preoperative SABR for Early-Stage Breast Cancer: Introduction of a Novel Form of Accelerated Partial Breast Radiation Therapy

Authors: Liveringhouse, Casey L., Mills, Matthew N., Ahmed, Kamran A., Washington, Iman R., Lee, Marie C., Khakpour, Nazanin, Laronga, Christine, Czerniecki, Brian, Soliman, Hatem, Weinfurtner, Robert J., Rosa, Marilin, Kim, Youngchul, Stringfield, Olya, Abdalah, Mahmoud, Diaz, Roberto, Montejo, Michael

Source: International journal of radiation oncology, biology, physics. 116(3):611-616

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194221967.0x000001&indx=1&recIds=ETOCvdc_100194221967.0x000001

A Real-World Data Retrospective Cohort Study of HER2-positive, Early-Stage Breast Cancer in Patients 70 Years of Age or Older: Natural History, Treatment Patterns, and Outcomes

Authors: Bari, Shahla, Li, Jiannong, Kang, Di, Jameel, Zena, Czerniecki, Brian J., Costa, Ricardo L.B.

Source: Clinical breast cancer. 23(4):378-387

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A 7-Gene Biosignature for Ductal Carcinoma in situ of the Breast Identifies Subpopulations of HER2-positive Patients With Distinct Recurrence Rates After Breast-Conserving Surgery and Radiation Therapy

Authors: Vicini, Frank ^{1, ⁎}, Shah, Chirag ², Mittal, Karuna ³, Abraham, Jame ², Kruse, Megan ², Weinmann, Sheila ⁴, Leo, Michael ⁴, Rabinovitch, Rachel ⁵, Wärnberg, Fredrik ⁶, Whitworth, Pat W. ³, Czerniecki, Brian J. ⁷, Shivers, Steven C. ³, Bremer, Troy ³

Source: In Clinical Breast Cancer February 2025 25(2):e152-e158

Effect of Microporous Polysaccharide Particles in Patients Undergoing Mastectomy

Authors: Selfridge, Julia M., Sinner, Heather F., Whiting, Junmin, Sun, Weihong, Mallory, Melissa A., Hoover, Susan J., Kiluk, John V., Khakpour, Nazanin, Czerniecki, Brian J., Laronga, Christine, Mo, Qianxing, Lee, Marie C.

Source: In Clinical Breast Cancer December 2022 22(8):e922-e927

Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses

Authors: Mandula, Jessica K., Chang, Shiun, Mohamed, Eslam, Jimenez, Rachel, Sierra-Mondragon, Rosa A., Chang, Darwin C., Obermayer, Alyssa N., Moran-Segura, Carlos M., Das, Satyajit, Vazquez-Martinez, Julio A., Prieto, Karol, Chen, Ann, Smalley, Keiran S.M., Czerniecki, Brian, Forsyth, Peter, Koya, Richard C., Ruffell, Brian, Cubillos-Ruiz, Juan R., Munn, David H., Shaw, Timothy I., Conejo-Garcia, Jose R., Rodriguez, Paulo C.

Source: In Cancer Cell 10 October 2022 40(10):1145-1160

Current State of Cell Therapies for Breast Cancer

Authors: Gautam, Namrata, Elleson, Kelly M., Ramamoorthi, Ganesan, Czerniecki, Brian J.

Source: Cancer journal. 28(4):301-309

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167690048.0x000001&indx=1&recIds=ETOCvdc_100167690048.0x000001

A preclinical model of patient-derived cerebrospinal fluid circulating tumor cells for experimental therapeutics in leptomeningeal disease from melanoma

Authors: Law, Vincent, Chen, Zhihua, Vena, Francesca, Smalley, Inna, Macaulay, Robert, Evernden, Brittany R, Tran, Nam, Pina, Yolanda, Puskas, John, Caceres, Gisela, Bayle, Simon, Johnson, Joseph, Liu, James K C, Etame, Arnold, Vogelbaum, Michael, Rodriguez, Paulo, Duckett, Derek, Czerniecki, Brian, Chen, Ann, Smalley, Keiran S M, Forsyth, Peter A

Source: Neuro-oncology. 24(10):1673-1686

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100162536292.0x000001&indx=1&recIds=ETOCvdc_100162536292.0x000001

Disseminated cancer cells in breast cancer: Mechanism of dissemination and dormancy and emerging insights on therapeutic opportunities

Authors: Ramamoorthi, Ganesan, Kodumudi, Krithika, Gallen, Corey, Zachariah, Nadia Nocera, Basu, Amrita, Albert, Gabriella, Beyer, Amber, Snyder, Colin, Wiener, Doris, Costa, Ricardo L.B., Czerniecki, Brian J.

Source: Seminars in cancer biology. 78:78-89

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100155631134.0x000001&indx=1&recIds=ETOCvdc_100155631134.0x000001

MRI Response to Pre-operative Stereotactic Ablative Body Radiotherapy (SABR) in Early Stage ER/PR+ HER2- Breast Cancer correlates with Surgical Pathology Tumor Bed Cellularity

Authors: Weinfurtner, R. Jared, Raghunand, Natarajan, Stringfield, Olya, Abdalah, Mahmoud, Niell, Bethany L., Ataya, Dana, Williams, Angela, Mooney, Blaise, Rosa, Marilin, Lee, Marie C., Khakpour, Nazanin, Laronga, Christine, Czerniecki, Brian, Diaz, Roberto, Ahmed, Kamran, Washington, Iman, Montejo, Michael

Source: Clinical breast cancer. 22(2):e214-e223

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154988573.0x000001&indx=1&recIds=ETOCvdc_100154988573.0x000001

Quantitative Changes in Intratumoral Habitats on MRI Correlate With Pathologic Response in Early-stage ER/PR+ HER2− Breast Cancer Treated With Preoperative Stereotactic Ablative Body Radiotherapy

Authors: Jared Weinfurtner, R, Abdalah, Mahmoud, Stringfield, Olya, Ataya, Dana, Williams, Angela, Mooney, Blaise, Rosa, Marilin, Lee, Marie C, Khakpour, Nazanin, Laronga, Christine, Czerniecki, Brian, Diaz, Roberto, Ahmed, Kamran, Washington, Iman, Latifi, Kujtim, Niell, Bethany L, Montejo, Michael, Raghunand, Natarajan

Source: Journal of breast imaging. 4(3):273-284

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154649895.0x000001&indx=1&recIds=ETOCvdc_100154649895.0x000001

A pilot study incorporating HER2-directed dendritic cells into neoadjuvant therapy of early stage HER2+ER- breast cancer.

Authors: Soliman, Hatem, Aldrich, Amy, Abdo, Neveen, Han, Hyo, Soyano, Aixa, Costa, Ricardo, Armaghani, Avan, Kiluk, John, Khakpour, Nazanin, Lee, Marie Catherine, Hoover, Susan, Laronga, Christine, Niell, Bethany, Mooney, Blaise, Weinfurtner, Robert Jared, Rosa, Marilin, Czerniecki, Brian

Source: NPJ Breast Cancer; 3/17/2025, Vol. 11 Issue 1, p1-9, 9p

Alteration of the Tumor Microenvironment With Intratumoral Dendritic Cells Before Chemotherapy in ERBB2 Breast Cancer: A Nonrandomized Clinical Trial.

Authors: Han, Hyo S., Aldrich, Amy L., Garg, Saurabh K., Weinfurtner, R. Jared, Nguyen, Jonathan V., Mo, Qianxing, Whiting, Junmin, Childress, Jennifer, Soliman, Hatem, Costa, Ricardo, Armaghani, Avan, Soyano, Aixa, Kiluk, John, Hoover, Susan, Lee, Marie C., Khakpour, Nazanin, Shenoi, Nithin, Jameel, Zena, Koski, Gary K., Czerniecki, Brian J.

Source: JAMA Oncology; Feb2025, Vol. 11 Issue 2, p119-127, 9p

Nivolumab and Stereotactic Radiosurgery for Patients With Breast Cancer Brain Metastases: A Nonrandomized, Open-Label Phase 1b Study

Authors: Ahmed, Kamran A., Kim, Youngchul, Arrington, John A., Kim, Sungjune, DeJesus, Michelle, Soyano, Aixa E., Armaghani, Avan J., Costa, Ricardo L.B., Khong, Hung T., Loftus, Loretta S., Rosa, Marilin, Caudell, Jimmy J., Diaz, Roberto, Robinson, Timothy J., Etame, Arnold B., Tran, Nam D., Sahebjam, Solmaz, Soliman, Hatem H., Czerniecki, Brian J., Forsyth, Peter A., Yu, H. Michael, Han, Hyo S.

Source: In Advances in Radiation Oncology November-December 2021 6(6)

Feasibility of Axillary Lymph Node Localization and Excision Using Radar Reflector Localization

Authors: Sun, James, Henry, Danielle A., Carr, Michael J., Yazdankhahkenary, Adel, Laronga, Christine, Lee, M. Catherine, Hoover, Susan J., Sun, Weihong, Czerniecki, Brian J., Khakpour, Nazanin, Kiluk, John V.

Source: In Clinical Breast Cancer June 2021 21(3):e189-e193

Th1 cytokine interferon gamma improves response in HER2 breast cancer by modulating the ubiquitin proteasomal pathway

Authors: Jia, Yongsheng, Kodumudi, Krithika N., Ramamoorthi, Ganesan, Basu, Amrita, Snyder, Colin, Wiener, Doris, Pilon-Thomas, Shari, Grover, Payal, Zhang, Hongtao, Greene, Mark I., Mo, Qianxing, Tong, Zhongsheng, Chen, Yong-Zi, Costa, Ricardo L.B., Han, Hyo, Lee, Catherine, Soliman, Hatem, Conejo-Garcia, Jose R., Koski, Gary, Czerniecki, Brian J.

Source: In Molecular Therapy 7 April 2021 29(4):1541-1556

Real‐world benefit of combination palbociclib and endocrine therapy for metastatic breast cancer and correlation with neutropenia

Authors: Sun, James, Zhong, Xiaojun, Ma, Junjie, Sun, Weihong, Han, Hyo S., Soliman, Hatem H., Loftus, Loretta S., Costa, Ricardo L. B., Armaghani, Avan J., Soyano‐Muller, Aixa E., Czerniecki, Brian J., Lee, M. Catherine, Kiluk, John V., Khakpour, Nazanin, Hoover, Susan J., Laronga, Christine, Khong, Hung T.

Source: Cancer medicine. 10(21):7665-7672

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132963675.0x000001&indx=1&recIds=ETOCvdc_100132963675.0x000001

Immunotherapies in breast cancer: harnessing the cancer immunity cycle.

Authors: Lok, Vincent, Olson-McPeek, Sy, Spiegelhoff, Grace, Cortez, Jaqueline, Detz, David, Czerniecki, Brian

Source: Expert Opinion on Therapeutic Targets; Nov2024, Vol. 28 Issue 11, p925-935, 11p

Implant-sparing Mastectomy: An Alternative for Women Undergoing Mastectomy With Retropectoral Implants

Authors: Burke, Erin E., Laronga, Christine, Sun, Weihong, DeBiase, Steven, Naqvi, Syeda Mahrukh Hussnain, Fridley, Brooke, Czerniecki, Brian J., Hoover, Susan J., Khakpour, Nazanin, Kiluk, John V., Lee, Marie Catherine

Source: In Clinical Breast Cancer February 2020 20(1):e14-e19