Synergistic activity of Pitstop-2 and 1,6-hexanediol in aggressive human lung cancer cells.

Authors: Stefanello, Sílvio Terra¹, Mizdal, Caren Rigon¹, da Silva, Aline Franzen², Todesca, Luca Matteo¹, Soares, Félix Alexandre Antunes², Shahin, Victor¹, shahin@uni-muenster.de

Source: Discover Nano; 1/21/2025, Vol. 20 Issue 1, p1-8, 8p

Cost–benefit analysis of p16^INK4a immunocytology and liquid-based cytology triage after primary HPV testing for cervical cancer screening in China.

Authors: Zhou, Dachuang^1,2 (AUTHOR), Hou, Jun^3,4,5 (AUTHOR), Xi, Jiayi^1,2 (AUTHOR), Li, Yuan^1,2 (AUTHOR), Qu, Xinfeng^3,4,5 (AUTHOR) steve1005@icloud.com, Tang, Wenxi^1,2 (AUTHOR) tokammy@cpu.edu.cn, Wu, Ruifang^3,4,5 (AUTHOR) wurf100@126.com

Source: Infectious Agents & Cancer. 4/18/2025, Vol. 20 Issue 1, p1-12. 12p.

Subject Terms: *PROTEIN metabolism, *CYTOLOGY, *RESEARCH funding, *HERPESVIRUSES, *EARLY detection of cancer, *COST benefit analysis, *COLPOSCOPY, *SENSITIVITY & specificity (Statistics), *HEALTH care rationing, *EVALUATION, CERVIX uteri tumors

Geographic Terms: CHINA

Identification of phloem-specific proteinaSEOus structure heterogeneity in sieve element of Populus trichocarpa.

Authors: Kułak, Karolina¹ (AUTHOR) karolina.kulak@amu.edu.pl, Samelak-Czajka, Anna² (AUTHOR), Marszalek-Zenczak, Malgorzata² (AUTHOR), Michalak, Kornel M.¹ (AUTHOR), Trybus, Magdalena² (AUTHOR), Minicka, Julia³ (AUTHOR), Jackowiak, Paulina² (AUTHOR), Bagniewska-Zadworna, Agnieszka¹ (AUTHOR) agnieszka.bagniewska-zadworna@amu.edu.pl

Source: BMC Plant Biology. 4/10/2025, Vol. 25 Issue 1, p1-14. 14p.

Subject Terms: *SIEVE elements, *CYTOLOGY, *BLACK cottonwood, *PLANT genetics, *LIFE sciences

Scope and limitations of intraoperative cytological methods of diagnosis of ovarian tumors.

Authors: Ahsan, Erna¹ (AUTHOR), Gautam, Saurabh Kumar¹ (AUTHOR), Singh, Ashok¹ (AUTHOR), Kumar, Arvind¹ (AUTHOR) drarvindkumar10@gmail.com, Phulware, Ravi Hari¹ (AUTHOR)

Source: CytoJournal. 4/9/2025, Vol. 22, p1-10. 10p.

Subject Terms: *CYTOLOGY, *PREDICTIVE tests, *OVARIAN tumors, *DIAGNOSTIC errors, *DECISION making in clinical medicine, *OPERATIVE surgery, *FROZEN tissue sections, *MICROSCOPY, *STAINS & staining (Microscopy), *SENSITIVITY & specificity (Statistics)

The CD163 + tissue-infiltrating macrophages regulate ferroptosis in thyroid-associated ophthalmopathy orbital fibroblasts via the TGF-β/Smad2/3 signaling pathway.

Authors: Li, Xuemei^1,2,3,4,5 (AUTHOR), Wang, Siyi^1,2,4 (AUTHOR), Cao, Hanwen^1,2,4 (AUTHOR), Xu, Simin^1,2,4 (AUTHOR), Xiong, Chao^1,2,3,4,5 (AUTHOR), Yu, Jinhai^1,2,3,4,5 (AUTHOR), Chen, Yunxiu^1,2,4 (AUTHOR), Ren, Zhangjun^1,2,4 (AUTHOR), Li, Min^1,2,4 (AUTHOR), Hu, Ying^1,2,4 (AUTHOR), Gan, Puying^2,3,4,5 (AUTHOR), Xu, Qihua^1,2,3,4,5 (AUTHOR) xu7ganggang@163.com, Wang, Yaohua⁶ (AUTHOR) yaohua-w@eye.ac.cn, Liao, Hongfei^1,2,3,4,5 (AUTHOR) lhfzf@126.com

Source: Journal of Translational Medicine. 4/10/2025, Vol. 23 Issue 1, p1-17. 17p.

Subject Terms: *CYTOLOGY, *LIFE sciences, *GENE expression, *FIBROBLASTS, *TISSUE remodeling, *GENE ontology

Adipose-derived small extracellular vesicle miR-146a-5p targets Fbx32 to regulate mitochondrial autophagy and delay aging in skeletal muscle.

Authors: Qin, Mengran^1,2,3,4 (AUTHOR), Wang, Yan^1,2,3 (AUTHOR), Wang, Zihan⁵ (AUTHOR), Dong, Benchao^1,2,3 (AUTHOR), Yang, Peichuan^1,2,3 (AUTHOR), Liu, Youyi^1,2,3,5 (AUTHOR), Xi, Qianyun⁴ (AUTHOR) xqy0228@scau.edu.cn, Ma, Jianxiong^1,2,3 (AUTHOR) yjslwtg@126.com

Source: Journal of Nanobiotechnology. 4/10/2025, Vol. 23 Issue 1, p1-18. 18p.

Subject Terms: *CYTOLOGY, *MUSCLE aging, *LIFE sciences, *MUSCULAR atrophy, *MUSCLE growth

Characterization of β-glucosidase activity of a Lactiplantibacillus plantarum 6-phospho-β-glucosidase.

Authors: Godse, Ravish¹ (AUTHOR) ravish.godse@ssbs.edu.in, Fernandes, Joyleen M.^1,2 (AUTHOR) annmary1903@gmail.com, Kulkarni, Ram¹ (AUTHOR) ram.kulkarni@ssbs.edu.in

Source: Applied Microbiology & Biotechnology. 4/8/2025, Vol. 109 Issue 1, p1-12. 12p.

Subject Terms: *LIFE sciences, *CYTOLOGY, *HYDROLASES, *BIOCHEMICAL substrates, *GLUCOSIDES

Identification of lncRNAs in peripheral blood mononuclear cells associated with sepsis immunosuppression based on weighted gene co-expression network analysis.

Authors: Zhang, Wenjia¹ (AUTHOR) Cristianwood1006@outlook.com, Li, Yan¹ (AUTHOR) liyan_19801120@sina.com, Li, Gang¹ (AUTHOR) docligang@sina.cn, Zhang, Aijia² (AUTHOR) zhangaj0118@sina.com, Sun, Wende³ (AUTHOR) swd19880105@sina.com

Source: Hereditas. 4/7/2025, Vol. 162 Issue 1, p1-11. 11p.

Subject Terms: *MONONUCLEAR leukocytes, *CYTOLOGY, *LINCRNA, *LIFE sciences, *T helper cells

Analysis of the triage value of multigene methylation testing for CIN2 + in hrHPV-positive patients.

Authors: Lin, Caiyun¹ (AUTHOR), Zhu, Chenye¹ (AUTHOR), Xie, Meihua¹ (AUTHOR), Yang, Hua¹ (AUTHOR) yanghua@hainmc.edu.cn

Source: Infectious Agents & Cancer. 4/7/2025, Vol. 20 Issue 1, p1-10. 10p.

Subject Terms: *CERVICAL intraepithelial neoplasia, *CYTOLOGY, *PAPILLOMAVIRUSES, *DNA methylation, *CONFIDENCE intervals, *GENETIC testing, *MEDICAL triage, *SENSITIVITY & specificity (Statistics)

Transcriptomic characterization of human pancreatic CD206- and CD206 + macrophages.

Authors: Jonsson, Alexander¹ (AUTHOR) alexander.jonsson@igp.uu.se, Korsgren, Olle^1,2 (AUTHOR), Hedin, Anders¹ (AUTHOR)

Source: Scientific Reports. 4/8/2025, Vol. 15 Issue 1, p1-12. 12p.

Subject Terms: *CYTOLOGY, *LIFE sciences, *MEDICAL sciences, *EXTRACELLULAR matrix, *MEDICAL genetics

CRISPR-Cas9 genetic screens reveal regulation of TMPRSS2 by the Elongin BC-VHL complex.

Authors: Gabaev, Ildar^1,2 (AUTHOR), Rowland, Alexandra^1,2 (AUTHOR), Jovanovic, Emilija³ (AUTHOR), Gawden-Bone, Christian M.^1,2 (AUTHOR), Crozier, Thomas W. M.^1,2 (AUTHOR), Teixeira-Silva, Ana^1,2 (AUTHOR), Greenwood, Edward J. D.^1,2 (AUTHOR), Gerber, Pehuén Pereyra^1,2 (AUTHOR), Wit, Niek^1,2 (AUTHOR), Nathan, James A.^1,2 (AUTHOR), Matheson, Nicholas J.^1,2,4 (AUTHOR), Lehner, Paul J.^1,2 (AUTHOR) pjl30@cam.ac.uk

Source: Scientific Reports. 4/7/2025, Vol. 15 Issue 1, p1-17. 17p.

Subject Terms: *SARS-CoV-2 Omicron variant, *CYTOLOGY, *LIFE sciences, *SERINE proteinases, *MEMBRANE proteins

Analysis of cellular responses following interaction with extracellular vesicles derived from HEK293T and human adipose derived stem cells.

Authors: Zhang, Weixu¹ (AUTHOR), Obuchi, Satoe² (AUTHOR), Teramura, Yuji^1,2,3 (AUTHOR) y.teramura@aist.go.jp

Source: Scientific Reports. 4/7/2025, Vol. 15 Issue 1, p1-11. 11p.

Subject Terms: *CYTOLOGY, *CELL migration, *EXTRACELLULAR vesicles, *HUMAN stem cells, *LIFE sciences

FHL2 deteriorates IL-1β induced inflammation, apoptosis, and extracellular matrix degradation in chondrocyte-like ATDC5 cells by mTOR and NF-ĸB pathways.

Authors: Li, Yicheng¹ (AUTHOR), Wang, Fei¹ (AUTHOR), Ji, Baochao¹ (AUTHOR), Amati, Abdusami¹ (AUTHOR), Cao, Li¹ (AUTHOR) xjbone@sina.com

Source: BMC Musculoskeletal Disorders. 4/4/2025, Vol. 26 Issue 1, p1-11. 11p.

Subject Terms: *LIFE sciences, *CYTOLOGY, *BCL-2 proteins, *EXTRACELLULAR matrix, *TRANSCRIPTION factors

Lacc1-engineered extracellular vesicles reprogram mitochondrial metabolism to alleviate inflammation and cartilage degeneration in TMJ osteoarthritis.

Authors: Hu, Xiaofeng¹ (AUTHOR), Xie, Jian¹ (AUTHOR) xjboom@163.com, Su, Jiansheng¹ (AUTHOR) sjs@tongji.edu.cn

Source: Journal of Nanobiotechnology. 4/5/2025, Vol. 23 Issue 1, p1-20. 20p.

Subject Terms: *MEDICAL sciences, *CYTOLOGY, *METABOLIC reprogramming, *LIFE sciences, *EXTRACELLULAR vesicles, *HOMEOSTASIS, *GLYCOLYSIS

Pulmonary Adenocarcinoma Updates: Histology, Cytology, and Grading.

Authors: Sharma, Jake¹, Fang Zhou¹, Moreira, Andre L.¹ Andre.moreira@nyulangone.org

Source: Archives of Pathology & Laboratory Medicine. Apr2025, Vol. 149 Issue 4, p82-86. 5p.

Subject Terms: *ADENOCARCINOMA, *CYTOLOGY, *BIOPSY, *CANCER patients, *LUNG tumors, *LUNG cancer, *TUMOR classification, *GENETIC mutation, *HISTOLOGY, *MOLECULAR pathology, *MEDICAL triage

The Diagnostic Accuracy of Claudin-4 Immunochemistry in Differentiating Metastatic Carcinomas From Mesothelial Processes in Serous Effusion Cytology: A Systematic Review and Meta-analysis.

Authors: Kleinaki, Maria¹, Vey, Johannes A.², Awounvo, Sinclair², Ishak, Angela^1,3, Arnaouti, Maria¹, Han Suk Ryu⁴, Nikas, Ilias P.¹ nikas.ilias@ucy.ac.cy

Source: Archives of Pathology & Laboratory Medicine. Apr2025, Vol. 149 Issue 4, p381-388. 8p.

Subject Terms: *BODY fluid analysis, *CYTOLOGY, *PERICARDIAL effusion, *IMMUNOCHEMISTRY, *DIFFERENTIAL diagnosis, *TUMOR markers, *CANCER patients, *META-analysis, *DESCRIPTIVE statistics, *METASTASIS, *SYSTEMATIC reviews, *MEDLINE, *ODDS ratio, *MEDICAL databases, *MESOTHELIOMA, *ONLINE information services, *CONFIDENCE intervals, *SENSITIVITY & specificity (Statistics), *MEMBRANE proteins

Performance Characteristics of Incisional and Core Needle Biopsies for Diagnosis in Parotid Gland: Single-Institutional Experience and Assessment of the Value of a Milan System for Reporting Salivary Gland Cytopathology--Like Risk Stratification Model.

Authors: Rammal, Rayan¹ rammalr@mskcc.org, Qian Wang¹, Ohori, N. Paul¹, Kubik, Mark², Chiosea, Simion I.¹, Seethala, Raja R.¹

Source: Archives of Pathology & Laboratory Medicine. Apr2025, Vol. 149 Issue 4, p328-339. 12p.

Subject Terms: *CYTOLOGY, *RISK assessment, *SQUAMOUS cell carcinoma, *RECEIVER operating characteristic curves, *FISHER exact test, *KRUSKAL-Wallis Test, *RETROSPECTIVE studies, *LYMPHOMAS, *MANN Whitney U Test, *DESCRIPTIVE statistics, *METASTASIS, *ADENOMA, *NEEDLE biopsy, *MEDICAL records, *ACQUISITION of data, *CANCER cells, *SALIVARY glands, *COMPARATIVE studies, *CONFIDENCE intervals, *DATA analysis software, *SENSITIVITY & specificity (Statistics), *NONPARAMETRIC statistics, *DISEASE risk factors, PAROTID gland tumors

Reduction of microRNA-221 in BVDV infection enhances viral replication by targeting the ATG7-mediated autophagy pathway.

Authors: Chen, Zihan¹ (AUTHOR), Wang, Jingyu¹ (AUTHOR), Lu, Baochun² (AUTHOR), Meng, Wenxin¹ (AUTHOR), Zhu, Yufan¹ (AUTHOR), Jiang, Qifeng¹ (AUTHOR), Gao, Duo¹ (AUTHOR), Ma, Zihang¹ (AUTHOR), Zeng, Huijuan¹ (AUTHOR), Chen, Jinping¹ (AUTHOR), Liu, Shizhe¹ (AUTHOR), Wang, Zhen¹ (AUTHOR), Jia, Kun¹ (AUTHOR) jiakun@scau.edu.cn

Source: Irish Veterinary Journal. 4/2/2025, Vol. 78 Issue 1, p1-14. 14p.

Subject Terms: *MEDICAL sciences, *CYTOLOGY, *LIFE sciences, *MEDICAL microbiology, *ANIMAL culture

ECM-binding properties of extracellular vesicles: advanced delivery strategies for therapeutic applications in bone and joint diseases.

Authors: Wang, Peng^1,2 (AUTHOR), Husch, Johanna F. A.^2,3 (AUTHOR), Arntz, Onno J.^1,2 (AUTHOR), van der Kraan, Peter M.^1,2 (AUTHOR), van de Loo, Fons A. J.^1,2 (AUTHOR), van den Beucken, Jeroen J. J. P.^2,3 (AUTHOR) jeroen.vandenbeucken@radboudumc.nl

Source: Cell Communication & Signaling. 4/2/2025, Vol. 23 Issue 1, p1-17. 17p.

Subject Terms: *BIOENGINEERING, *CYTOLOGY, *LIFE sciences, *CARTILAGE regeneration, *JOINTS (Anatomy)

The potential mechanism of MicroRNA involvement in the regulation of muscle development in weaned piglets by tryptophan and its metabolites.

Authors: He, Tianle^1,2 (AUTHOR), Chen, Qingyun¹ (AUTHOR), Li, Huifeng¹ (AUTHOR), Mao, Jiani¹ (AUTHOR), Luo, Ju¹ (AUTHOR), Ma, Dengjun¹ (AUTHOR), Yang, Zhenguo¹ (AUTHOR) guoguo00002@163.com

Source: BMC Genomics. 4/1/2025, Vol. 26 Issue 1, p1-15. 15p.

Subject Terms: *MUSCLE growth, *CYTOLOGY, *LIFE sciences, *CELL proliferation, *BIOCHEMISTRY, *TRP channels, *PIGLETS