Insights into medication-induced liver injury: Understanding and management strategies

Authors: Vatsalya Tiwari, Shrishti Shandily, Jessielina Albert, Vaibhav Mishra, Manoj Dikkatwar, Rohit Singh, Sujit Kumar Sah, Sharad Chand

Source: Toxicology Reports, Vol 14, Iss , Pp 101976- (2025)

Subject Terms: Acute liver toxicity, Cytochrome P-450 enzyme, Drug metabolism, Hepatotoxicity, Liver failure, Toxicology. Poisons, RA1190-1270

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Relation: http://www.sciencedirect.com/science/article/pii/S2214750025000940; https://doaj.org/toc/2214-7500

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CHANGE IN INTESTINAL FLORA AND ITS ASSOCIATION WITH LIVER CYP2E1 IN MICE WITH LIVER INJURY INDUCED BY HIGH-INTENSITY ATORVASTATIN

Authors: SONG Bingxue, SONG Yuqing, LIU Xin, YU Haichu, XIN Hui, LIANG Hui

Source: 精准医学杂志, Vol 38, Iss 6, Pp 494-498 (2023)

Subject Terms: gastrointestinal microbiome, atorvastatin, chemical and drug induced liver injury, cytochrome p-450 enzyme system, rna, messenger, superoxide dismutase, lactobacillus, Medicine

File Description: electronic resource

Relation: https://jpmed.qdu.edu.cn/fileup/2096-529X/PDF/1701928426310-1484774633.pdf; https://doaj.org/toc/2096-529X

Access URL: https://doaj.org/article/2c9cdc7a98924659903f6a31c6bba77a

Coadministration of fluconazole to boost subtherapeutic sirolimus concentrations: A case report

Authors: Camilo Scherkl, Andreas D. Meid, Sven E. Cuntz, Laura Classen, Johanna Weiss, David Czock, Walter E. Haefeli

Source: Pharmacology Research & Perspectives, Vol 12, Iss 3, Pp n/a-n/a (2024)

Subject Terms: cytochrome P‐450 enzyme inhibitors, fluconazole, pharmacokinetics, sirolimus, Therapeutics. Pharmacology, RM1-950

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Relation: https://doaj.org/toc/2052-1707

Access URL: https://doaj.org/article/29aa79bdc38c451f872ab11996092463

Pharmacogenetics to Avoid Adverse Drug Reactions

Contributors: López-Fernández, Luis A.

Subject Terms: 5-fluorouracil, capecitabine, fluoropyrimidine, thymidylate synthase, thymidylate synthase enhancer region, upstream stimulatory factor 1, adverse drug reactions, pharmacogenomics, epistasis, random forest, statin, cardiovascular disease, colorectal cancer, personalised medicine, toxicity, (es)citalopram, drug-gene-interaction, drug-drug-interaction, drug-drug-gene-interaction, the PharmLines initiative, antipsychotic agents, pharmacogenetics, cytochrome P-450 enzyme system, psychotic disorders, precision medicine, direct oral anticoagulants, clinical implementation, atorvastatin, SLCO1B1, HLA, cutaneous adverse drug reaction, SCAR, genetic polymorphism, antiepileptics, CYP450 enzymes, platelet reactivity, single-nucleotide variants, acute coronary syndrome, clopidogrel, genotype, allele, polymorphism, HLA B, CYP2C9*3, cutaneous adverse drug reactions (CADRs), anti-epileptic drugs (AEDS), phenytoin (PHT), genetic risk factors, South India, India, cardiology, adverse events, guidelines, Medicine and Nursing

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Access URL: https://directory.doabooks.org/handle/20.500.12854/79654
https://mdpi.com/books/pdfview/book/5039

Association of CYP1A1*2C Variant (Ile464Val Polymorphism) and Some Hematological Parameters with Acute Myeloid Leukemia (AML) and Chronic Myeloid Leukemia (CML) in Erbil-Iraq.

Authors: Sumaya Basit Abdullah, Mustafa Saber Al-Attar

Source: Zanco Journal of Pure and Applied Sciences, Vol 35, Iss 3 (2023)

Subject Terms: CYP1A1*2C, AML, CML, Cytochrome P-450 Enzyme, Polymorphism, Technology, Science

File Description: electronic resource

Relation: https://zancojournal.su.edu.krd/index.php/JPAS/article/view/631; https://doaj.org/toc/2218-0230; https://doaj.org/toc/2412-3986

Access URL: https://doaj.org/article/10482589b4fd4be88cbfaf4cc5321526

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Fatal poisoning case involving drug interaction due to the inhibition of cytochrome P450

Authors: Kinoshita Hiroshi, Tanaka Naoko, Kumihashi Mitsuru, Jamal Mostofa, Ito Asuka, Yamashita Tadayoshi, Ameno Kiyoshi

Source: Vojnosanitetski Pregled, Vol 78, Iss 5, Pp 563-566 (2021)

Subject Terms: autopsy, cytochrome p-450 enzyme system, drug interactions, ethanol, forensic pathology, phenothiazines, poisoning, psychotropic drugs, Medicine (General), R5-920

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Relation: https://doaj.org/toc/0042-8450; https://doaj.org/toc/2406-0720

Access URL: https://doaj.org/article/3e9a972ae40745cf9195e80787420cad

A child with Kawasaki disease and genetic warfarin sensitivity from CYP2C9 and VKORC1 gene variants

Authors: Myeongseob Lee, Lucy Youngmin Eun

Source: Pediatric Emergency Medicine Journal, Vol 7, Iss 2, Pp 140-144 (2020)

Subject Terms: anticoagulants, coronary aneurysm, cytochrome p-450 enzyme system, mucocutaneous lymph node syndrome, warfarin, Medicine

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Relation: http://pemj.org/upload/pdf/pemj-2020-00143.pdf; https://doaj.org/toc/2383-4897; https://doaj.org/toc/2508-5506

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The Blind Spot of Pharmacology: A Scoping Review of Drug Metabolism in Prematurely Born Children

Authors: Mette Louise Mørk, Jón Trærup Andersen, Ulrik Lausten-Thomsen, Christina Gade

Source: Frontiers in Pharmacology, Vol 13 (2022)

Subject Terms: infant, premature, pharmacokinetics, cytochrome P-450 enzyme system, pharmaceutical preparations, Therapeutics. Pharmacology, RM1-950

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Relation: https://www.frontiersin.org/articles/10.3389/fphar.2022.828010/full; https://doaj.org/toc/1663-9812

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Comparison of clinical pharmacology of voriconazole and posaconazole

Authors: Beata M. Sienkiewicz, Łukasz Łapiński, Anna Wiela-Hojeńska

Source: Contemporary Oncology, Vol 20, Iss 5, Pp 365-373 (2016)

Subject Terms: voriconazole, posaconazole, clinical pharmacology, cytochrome P-450 enzyme system, drug monitoring, Medicine

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Relation: https://www.termedia.pl/Comparison-of-clinical-pharmacology-of-voriconazole-and-posaconazole,3,28897,1,1.html; https://doaj.org/toc/1428-2526; https://doaj.org/toc/1897-4309

Access URL: https://doaj.org/article/c7ce4e251ba8489680f50bc2951fdb09

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Association of The Common CYP1A1*2C Variant (Ile462Val Polymorphism) with Chronic Myeloid Leukemia (CML) in Patients Undergoing Imatinib Therapy

Authors: Samyuktha Lakkireddy, Sangeetha Aula, Swamy AVN, Atya Kapley, Raghunadha Rao Digumarti, Kaiser Jamil

Source: Cell Journal, Vol 17, Iss 3, Pp 510-519 (2015)

Subject Terms: Cytochrome P-450 Enzyme System, CYP1A1, Polymorphism, Chronic Myeloid Leukemia, Imatinib, Medicine, Science

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Relation: http://celljournal.org/web/journal/article/985/download; https://doaj.org/toc/2228-5806; https://doaj.org/toc/2228-5814

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Immunohistochemical evaluation of proliferation, apoptosis and steroidogenic enzymes in the ovary of rats with polycystic ovary

Authors: Lombardi, Leonardo Augusto, Simões, Ricardo Santos, Maganhin, Carla Cristina, Baracat, Maria Cândida Pinheiro, Silva-Sasso, Gisela Rodrigues, Florencio-Silva, Rinaldo, Soares Jr, José Maria, Baracat, Edmund Chada

Source: Revista da Associação Médica Brasileira. January 2014 60(4)

Subject Terms: polycystic ovary syndrome, ovary, ovarian cysts, apoptosis, cell proliferation, cytochrome P-450 enzyme eystem, rats, female

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Access URL: http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302014000400349

Adrenal mitochondria and steroidogenesis: from individual proteins to functional protein assemblies

Authors: Andrew Midzak, Vassilios Papadopoulos

Source: Frontiers in Endocrinology, Vol 7 (2016)

Subject Terms: Cytochrome P-450 Enzyme System, Endoplasmic Reticulum, Mitochondria, Voltage-Dependent Anion Channels, steroidogenic acute regulatory protein, Translocator protein, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

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Relation: http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00106/full; https://doaj.org/toc/1664-2392

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Drug-induced liver toxicity and prevention by herbal antioxidants: an overview

Authors: Divya eSingh, William eCho, Ghanshyam eUpadhyay

Source: Frontiers in Physiology, Vol 6 (2016)

Subject Terms: Cytochrome P-450 Enzyme System, Herbal Medicine, Oxidative Stress, Antioxidant Enzymes, Drug Mediated Liver Toxicity, Physiology, QP1-981

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Relation: http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00363/full; https://doaj.org/toc/1664-042X

Access URL: https://doaj.org/article/5aa93ac37ced42d5b8509ca67b85a3ac

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Molecular aspects of oxidative drug metabolizing enzymes : their significance in environmental toxicology, chemical carcinogenesis, and health

Authors: Hodgson, Ernest, 1932, Schenkman, John B., Arinç, Emel., NATO Advanced Study Institute on Molecular Aspects of Drug Metabolizing Enzymes (Kus̜adası, Turkey) : (1993)

Access URL: http://hdl.handle.net/2027/mdp.39015034259336

Human cytochrome P450-mediated metabolism of nicotine and tobacco-specific carcinogens : N-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone

Authors: Schlicht, Kari Elizabeth.

Access URL: http://hdl.handle.net/2027/umn.31951p010743558

Effect of genotype on CYP2C9 inhibition

Authors: Kumar, Vikas.

Access URL: http://hdl.handle.net/2027/umn.31951p01057014v

Studies to characterize pharmacokinetic profiles of dextromethorphan, flurbiprofen, midazolam, tiletamine and zolazepam in pigs and to elucidate effect of hemorrhagic shock on cytochrome P450 activities

Authors: Kumar, Atul.

Access URL: http://hdl.handle.net/2027/umn.31951p01074233m