4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors

Authors: Gavara, Laurent, Sevaille, Laurent, De Luca, Filomena, Mercuri, Paola, Bebrone, Carine, Feller, Georges, Legru, Alice, Cerboni, Giulia, Tanfoni, Silvia, Baud, Damien, Cutolo, Giuliano, Bestgen, Benoît, Chelini, Giulia, Verdirosa, Federica, Sannio, Filomena, Pozzi, Cecilia, Benvenuti, Manuela, Kwapien, Karolina, Fischer, Marina, Becker, Katja, Frère, Jean-Marie, Mangani, Stefano, Gresh, Nohad, Berthomieu, Dorothée, Galleni, Moreno, Docquier, Jean-Denis, Hernandez, Jean-François

Source: In European Journal of Medicinal Chemistry 15 December 2020 208

Capillary electrophoresis with dual detection UV/C4D for monitoring myrosinase-mediated hydrolysis of thiol glucosinolate designed for gold nanoparticle conjugation

Authors: Claude, Bérengère, Cutolo, Giuliano, Farhat, Amal, Zarafu, Irina, Ionita, Petre, Schuler, Marie, Tatibouët, Arnaud, Morin, Philippe, Nehmé, Reine

Source: In Analytica Chimica Acta 28 November 2019 1085:117-125

The myrosinase-glucosinolate system to generate neoglycoproteins: A case study targeting mannose binding lectins

Authors: Cutolo, Giuliano, Didak, Blanka, Tomas, Josip, Roubinet, Benoit, Lafite, Pierre, Nehmé, Reine, Schuler, Marie, Landemarre, Ludovic, Tatibouët, Arnaud

Source: In Carbohydrate Research June 2022 516

HSP27 Inhibitory Activity against Caspase‑3 Cleavage and Activation by Caspase‑9 Is Enhanced by Chaperone O‑GlcNAc Modification in Vitro.

Authors: Wang, Binyou, Moon, Stuart P., Cutolo, Giuliano, Javed, Afraah, Ahn, Benjamin S., Ryu, Andrew H., Pratt, Matthew R.

Source: ACS Chemical Biology; 8/18/2023, Vol. 18 Issue 8, p1698-1704, 7p

Your mother was right, washing matters: An alkyne-analog of ibuprofen reveals unwanted reactivity of aromatic compounds with proteins during copper-catalyzed click chemistry

Authors: Cutolo, Giuliano, Shankar, Sahiti N., Pratt, Matthew R.

Source: In Bioorganic & Medicinal Chemistry Letters 15 September 2021 48

Artificial Fluorescent Glucosinolates (F-GSLs) Are Transported by the Glucosinolate Transporters GTR1/2/3.

Authors: Kanstrup, Christa, Jimidar, Claire C., Tomas, Josip, Cutolo, Giuliano, Crocoll, Christoph, Schuler, Marie, Klahn, Philipp, Tatibouët, Arnaud, Nour-Eldin, Hussam Hassan

Source: International Journal of Molecular Sciences; Jan2023, Vol. 24 Issue 2, p920, 26p

Subject Terms: GLUCOSINOLATES, BINDING site assay, XENOPUS laevis, HIGH throughput screening (Drug development), PEPTIDES, FLUORESCEIN, PLANT metabolites

4‑Deoxy-4-fluoro-GalNAz (4FGalNAz) Is a Metabolic Chemical Reporter of O‑GlcNAc Modifications, Highlighting the Notable Substrate Flexibility of O‑GlcNAc Transferase.

Authors: Jackson, Emma G., Cutolo, Giuliano, Yang, Bo, Yarravarapu, Nageswari, Burns, Mary W. N., Bineva-Todd, Ganka, Roustan, Chloë, Thoden, James B., Lin-Jones, Halley M., van Kuppevelt, Toin H., Holden, Hazel M., Schumann, Benjamin, Kohler, Jennifer J., Woo, Christina M., Pratt, Matthew R.

Source: ACS Chemical Biology; 1/21/2022, Vol. 17 Issue 1, p159-170, 12p

Comparison of N‑Acetyl-Glucosamine to Other Monosaccharides Reveals Structural Differences for the Inhibition of α‑Synuclein Aggregation.

Authors: Galesic, Ana, Rakshit, Ananya, Cutolo, Giuliano, Pacheco, Ricardo Palos, Balana, Aaron T., Moon, Stuart P., Pratt, Matthew R.

Source: ACS Chemical Biology; 1/15/2021, Vol. 16 Issue 1, p14-19, 6p

Synthesis of glycosyl sulfoximines by a highly chemo- and stereoselective NH- and O-transfer to thioglycosides.

Authors: Tota, Arianna, Carlucci, Claudia, Pisano, Luisa, Cutolo, Giuliano, Clarkson, Guy J., Romanazzi, Giuseppe, Degennaro, Leonardo, Bull, James A., Rollin, Patrick, Luisi, Renzo

Source: Organic & Biomolecular Chemistry; 5/28/2020, Vol. 18 Issue 20, p3893-3897, 5p

Diverted Natural Lossen-type Rearrangement for Bioconjugation through in Situ Myrosinase-Triggered Isothiocyanate Synthesis.

Authors: Fredy, Jean Wilfried, Cutolo, Giuliano, Poret, Benjamin, Nehmé, Reine, Hubert-Roux, Marie, Gandolfo, Pierrick, Castel, Hélène, Schuler, Marie, Tatibouët, Arnaud, Sabot, Cyrille, Renard, Pierre-Yves

Source: Bioconjugate Chemistry; May2019, Vol. 30 Issue 5, p1385-1394, 10p