p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway

Authors: Fondevila, Marcos F., Novoa, Eva, Gonzalez-Rellan, Maria J., Fernandez, Uxia, Heras, Violeta, Porteiro, Begoña, Parracho, Tamara, Dorta, Valentina, Riobello, Cristina, da Silva Lima, Natalia, Seoane, Samuel, Garcia-Vence, Maria, Chantada-Vazquez, Maria P., Bravo, Susana B., Senra, Ana, Leiva, Magdalena, Marcos, Miguel, Sabio, Guadalupe, Perez-Fernandez, Roman, Dieguez, Carlos, Prevot, Vincent, Schwaninger, Markus, Woodhoo, Ashwin, Martinez-Chantar, Maria L., Schwabe, Robert, Cubero, Francisco J., Varela-Rey, Marta, Crespo, Javier, Iruzubieta, Paula, Nogueiras, Ruben

Source: In Cell Reports Medicine 20 February 2024 5(2)

Role of EpCAM+ CD133+ extracellular vesicles in steatosis to steatohepatitis transition in NAFLD

Authors: Muñoz‐Hernández, Rocío, Gato, Sheila, Gil‐Gómez, Antonio, Aller, Rocío, Rojas, Angela, Morán, Laura, Gallego, Javier, Blázquez‐López, Elena, Gallego‐Durán, Rocío, Montero‐Vallejo, Rocío, García‐Fernández, Vanessa, Maya‐Miles, Douglas, Rico, María del C, Cubero, Francisco J, Vaquero, Javier, Ampuero, Javier, Bañares, Rafael, Romero‐Gómez, Manuel

Source: Liver international. 43(9):1909-1919

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190087459.0x000001&indx=1&recIds=ETOCvdc_100190087459.0x000001

Inhibition of carnitine palmitoyltransferase 1A in hepatic stellate cells protects against fibrosis

Authors: Fondevila, Marcos F., Fernandez, Uxia, Heras, Violeta, Parracho, Tamara, Gonzalez-Rellan, Maria J., Novoa, Eva, Porteiro, Begoña, Alonso, Cristina, Mayo, Rebeca, da Silva Lima, Natalia, Iglesias, Cristina, Filliol, Aveline A., Senra, Ana, Delgado, Teresa C., Woodhoo, Ashwin, Herrero, Laura, Serra, Dolors, Prevot, Vincent, Schwaninger, Markus, López, Miguel, Dieguez, Carlos, Millet, Oscar, Mato, Jose M., Cubero, Francisco J., Varela-Rey, Marta, Iruzubieta, Paula, Crespo, Javier, Martinez-Chantar, Maria L., Schwabe, Robert F., Nogueiras, Ruben

Source: Journal of hepatology. 77(1):15-28

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100165884444.0x000001&indx=1&recIds=ETOCvdc_100165884444.0x000001

Hepatocyte KLF6 expression affects FXR signalling and the clinical course of primary sclerosing cholangitis

Authors: Sydor, Svenja, Manka, Paul, Buren, Lea, Theurer, Sarah, Schwertheim, Suzan, Best, Jan, Heegsma, Janette, Saeed, Ali, Vetter, Diana, Schlattjan, Martin, Dittrich, Anna, Fiel, Maria I., Baba, Hideo A., Dechêne, Alexander, Cubero, Francisco J., Gerken, Guido, Canbay, Ali, Moshage, Han, Friedman, Scott L., Faber, Klaas Nico, Bechmann, Lars P., Lleo, Ana

Source: Liver international. 40(9):2172-2181

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100117441345.0x000001&indx=1&recIds=ETOCvdc_100117441345.0x000001

High Prevalence of Ibuprofen Drug-Induced Liver Injury in Spanish and Latin-American Registries

Authors: Zoubek, Miguel E., González-Jimenez, Andres, Medina-Cáliz, Inmaculada, Robles-Díaz, Mercedes, Hernandez, Nelia, Romero-Gómez, Manuel, Bessone, Fernando, Hallal, Hacibe, Cubero, Francisco J., Lucena, M. Isabel, Stephens, Camilla, Andrade, Raúl J.

Source: In Clinical Gastroenterology and Hepatology February 2018 16(2):292-294

Cirrhosis‐downregulated LSECtin can be retrieved by cytokines, shifts the TLR‐induced LSECs secretome and correlates with the hepatic Th response.

Authors: Martínez‐López, Sebastián, Ángel‐Gomis, Enrique, Gómez‐Hurtado, Isabel, Fernández‐Iglesias, Anabel, Morante, Javier, Gracia‐Sancho, Jordi, Boix, Paula, Cubero, Francisco J., Zapater, Pedro, Caparrós, Esther, Francés, Rubén

Source: Liver International; Apr2024, Vol. 44 Issue 4, p996-1010, 15p

Subject Terms: CHEMOKINES, CYTOKINES, REGULATORY T cells, T helper cells, IMMUNE response, HEPATORENAL syndrome

Enhanced expression of c-myc in hepatocytes promotes initiation and progression of alcoholic liver disease

Authors: Nevzorova, Yulia A., Cubero, Francisco J., Hu, Wei, Hao, Fengjie, Haas, Ute, Ramadori, Pierluigi, Gassler, Nikolaus, Hoss, Mareike, Strnad, Pavel, Zimmermann, Henning W., Tacke, Frank, Trautwein, Christian, Liedtke, Christian

Source: In Journal of Hepatology March 2016 64(3):628-640

Overexpression of c-myc in hepatocytes promotes activation of hepatic stellate cells and facilitates the onset of liver fibrosis

Authors: Nevzorova, Yulia A., Hu, Wei, Cubero, Francisco J., Haas, Ute, Freimuth, Julia, Tacke, Frank, Trautwein, Christian, Liedtke, Christian

Source: In BBA - Molecular Basis of Disease October 2013 1832(10):1765-1775

A Novel Mouse Model of Combined Hepatocellular-Cholangiocarcinoma Induced by Diethylnitrosamine and Loss of Ppp2r5d.

Authors: Domènech Omella, Judit, Cortesi, Emanuela E., Verbinnen, Iris, Remmerie, Michiel, Wu, Hanghang, Cubero, Francisco J., Roskams, Tania, Janssens, Veerle

Source: Cancers; Aug2023, Vol. 15 Issue 16, p4193, 27p

Subject Terms: GENETIC mutation, CHOLANGIOCARCINOMA, NITROSOAMINES, ANIMAL experimentation, AGE distribution, STEM cells, RESEARCH funding, TUMOR markers, HEPATOCELLULAR carcinoma, MICE

MECHANISMS OF LIVER FIBROSIS ASSOCIATED WITH EXPERIMENTAL FASCIOLA HEPATICA INFECTION: ROLES OF FAS2 PROTEINASE AND HEPATIC STELLATE CELL ACTIVATION

Authors: Marcos, Luis A., Terashima, Angélica, Yi, Pedro, Andrade, Roy, Cubero, Francisco J., Albanis, Efsevia, Gotuzzo, Eduardo, Espinoza, Jose R., Friedman, Scott L.

Source: The Journal of Parasitology, 2011 Feb 01. 97(1), 82-87.

Access URL: https://www.jstor.org/stable/23019031

Loss of Caspase-8 Protects Mice Against Inflammation-Related Hepatocarcinogenesis but Induces Non-Apoptotic Liver Injury

Authors: Liedtke, Christian, Bangen, Jörg–Martin, Freimuth, Julia, Beraza, Naiara, Lambertz, Daniela, Cubero, Francisco J., Hatting, Maximilian, Karlmark, Karlin R., Streetz, Konrad L., Krombach, Gabriele A., Tacke, Frank, Gassler, Nikolaus, Riethmacher, Dieter, Trautwein, Christian

Source: In Gastroenterology December 2011 141(6):2176-2187

Protective role of c‐Jun N‐terminal kinase‐2 (JNK2) in ibuprofen‐induced acute liver injury.

Authors: Zoubek, Miguel E, Woitok, Marius M, Sydor, Svenja, Nelson, Leonard J, Bechmann, Lars P, Lucena, Maria I, Andrade, Raul J, Bast, Aalt, Koek, Ger H, Trautwein, Christian, Cubero, Francisco J

Source: Journal of Pathology; Jan2019, Vol. 247 Issue 1, p110-122, 13p

Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis

Authors: Liao, Lijun, Schneider, Kai Markus, Galvez, Eric J C, Frissen, Mick, Marschall, Hanns-Ulrich, Su, Huan, Hatting, Maximilian, Wahlstro¨m, Annika, Haybaeck, Johannes, Puchas, Philip, Mohs, Antje, Peng, Jin, Bergheim, Ina, Nier, Anika, Hennings, Julia, Reißing, Johanna, Zimmermann, Henning W, Longerich, Thomas, Strowig, Till, Liedtke, Christian, Cubero, Francisco J, Trautwein, Christian

Source: Gut; 2019, Vol. 68 Issue: 8 p1477-1492, 16p

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

Pattern of expression of the GNT1 gene and activation of UGT1A during the perinatal development in rat

Authors: Cubero, Francisco J., Ortiz, Agustin, Cantarino, Helena, Arza, Elvira, Mula, Nieves, Barrutia, Socorro García, Maganto, Paloma, a<%2Fce%3Asup>%22">Arahuetes, Rosa M