Sensitivity to PI3K and AKT inhibitors is mediated by divergent molecular mechanisms in subtypes of DLBCL

Authors: Erdmann, Tabea, Klener, Pavel, Lynch, James T., Grau, Michael, Vočková, Petra, Molinsky, Jan, Tuskova, Diana, Hudson, Kevin, Polanska, Urszula M., Grondine, Michael, Mayo, Michele, Dai, Beiying, Pfeifer, Matthias, Erdmann, Kristian, Schwammbach, Daniela, Zapukhlyak, Myroslav, Staiger, Annette M., Ott, German, Berdel, Wolfgang E., Davies, Barry R., Cruzalegui, Francisco, Trneny, Marek, Lenz, Peter, Barry, Simon T., Lenz, Georg

Source: In Blood 20 July 2017 130(3):310-322

TIPIN depletion leads to apoptosis in breast cancer cells

Authors: Baldeyron, Céline, Brisson, Amélie, Tesson, Bruno, Némati, Fariba, Koundrioukoff, Stéphane, Saliba, Elie, De Koning, Leanne, Martel, Elise, Ye, Mengliang, Rigaill, Guillem, Meseure, Didier, Nicolas, André, Gentien, David, Decaudin, Didier, Debatisse, Michelle, Depil, Stéphane, Cruzalegui, Francisco, Pierré, Alain, Roman-Roman, Sergio, Tucker, Gordon C., Dubois, Thierry

Source: In Molecular Oncology October 2015 9(8):1580-1598

Synthesis and pharmacological evaluation of thieno[2,3- b]pyridine derivatives as novel c-Src inhibitors

Authors: Pevet, Isabelle, Brulé, Cédric, Tizot, André, Gohier, Arnaud, Cruzalegui, Francisco, Boutin, Jean A., Goldstein, Solo

Source: In Bioorganic & Medicinal Chemistry 2011 19(8):2517-2528

A novel non-phosphorylated potential antitumoral peptide inhibits STAT3 biological activity

Authors: Dourlat, Jennifer, Liu, Wang-Qing, Sancier, Florence, Edmonds, Thomas, Pamonsinlapatham, Perayot, Cruzalegui, Francisco, Garbay, Christiane

Source: In Biochimie 2009 91(8):996-1002

Regulation of Intrasteric Inhibition of the Multifunctional Calcium/ Calmodulin-Dependent Protein Kinase

Authors: Cruzalegui, Francisco H., Kapiloff, Michael S., Morfin, John-Paul, Kemp, Bruce E., Rosenfeld, Michael G., Means, Anthony R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1992 Dec . 89(24), 12127-12131.

Access URL: https://www.jstor.org/stable/2360870

Calmodulin-dependent protein kinase II mediates inactivation of MPF and CSF upon fertilization of Xenopus eggs.

Authors: Lorca, Thierry, Cruzalegui, Francisco H., Fesquet, Didier

Source: Nature; November 18 1993, Vol. 366, p270-273, 4p

Regulation of intrasteric inhibition of the multifunctional calcium/calmodulin-dependent protein kinase.

Authors: Cruzalegui, Francisco H., Kapiloff, Michael S., Morfin, John-Paul

Source: Proceedings of the National Academy of Sciences of the United States of America; December 15 1992, Vol. 89, p12127-12131, 5p

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Control of Recruitment and Transcription-Activating Function of CBP Determines Gene Regulation by NMDA Receptors and L-Type Calcium Channels

Authors: Hardingham, Giles E., Chawla, Sangeeta, Cruzalegui, Francisco H., Bading, Hilmar ^*

Source: In Neuron April 1999 22(4):789-798

Fragment-Derived Selective Inhibitors of Dual-Specificity Kinases DYRK1A and DYRK1B

Authors: Lee Walmsley, David, Murray, James B., Dokurno, Pawel, Massey, Andrew J., Benwell, Karen, Fiumana, Andrea, Foloppe, Nicolas, Ray, Stuart, Smith, Julia, Surgenor, Allan E., Edmonds, Thomas, Demarles, Didier, Burbridge, Mike, Cruzalegui, Francisco, Kotschy, Andras, Hubbard, Roderick E.

Source: Journal of Medicinal Chemistry; July 2021, Vol. 64 Issue: 13 p8971-8991, 21p

Structure-Guided Discovery of Potent and Selective DYRK1A Inhibitors

Authors: Weber, Csaba, Sipos, Melinda, Paczal, Attila, Balint, Balazs, Kun, Vilibald, Foloppe, Nicolas, Dokurno, Pawel, Massey, Andrew J., Walmsley, David Lee, Hubbard, Roderick E., Murray, James, Benwell, Karen, Edmonds, Thomas, Demarles, Didier, Bruno, Alain, Burbridge, Mike, Cruzalegui, Francisco, Kotschy, Andras

Source: Journal of Medicinal Chemistry; May 2021, Vol. 64 Issue: 10 p6745-6764, 20p

ERK activation induces phosphorylation of Elk-1 at multiple S/T-P motifs to high stoichiometry.

Authors: Cruzalegui, Francisco H, Cano, Eva, Treisman, Richard

Source: Oncogene. 12/23/99, Vol. 18 Issue 56, p7948. 10p.

Subject Terms: *PROTEINS, *PHOSPHORYLATION, *IMMUNE serums, *PHOSPHATES, *PEPTIDES

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