CD4+ T-cell-derived IL-10 promotes CNS inflammation in mice by sustaining effector T cell survival

Authors: Yogev, Nir, Bedke, Tanja, Kobayashi, Yasushi, Brockmann, Leonie, Lukas, Dominika, Regen, Tommy, Croxford, Andrew L., Nikolav, Alexei, Hövelmeyer, Nadine, von Stebut, Esther, Prinz, Marco, Ubeda, Carles, Maloy, Kevin J., Gagliani, Nicola, Flavell, Richard A., Waisman, Ari, Huber, Samuel

Source: In Cell Reports 29 March 2022 38(13)

Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling

Authors: Chitu, Violeta, Biundo, Fabrizio, Shlager, Gabriel G.L., Park, Eun S., Wang, Ping, Gulinello, Maria E., Gokhan, Şölen, Ketchum, Harmony C., Saha, Kusumika, DeTure, Michael A., Dickson, Dennis W., Wszolek, Zbignew K., Zheng, Deyou, Croxford, Andrew L., Becher, Burkhard, Sun, Daqian, Mehler, Mark F., Stanley, E. Richard

Source: In Cell Reports 3 March 2020 30(9):3004-3019

Impact of high‐altitude therapy on type‐2 immune responses in asthma patients

Authors: Boonpiyathad, Tadech, Capova, Gertruda, Duchna, Hans‐Werner, Croxford, Andrew L., Farine, Herve, Dreher, Anita, Clozel, Martine, Schreiber, Juliane, Kubena, Petr, Lunjani, Nonhlanhla, Mirer, David, Rückert, Beate, Satitsuksanoa, Pattraporn, Tan, Ge, Groenen, Peter M. A., Bersuch, Eugen, Akdis, Mübeccel, Strasser, Daniel S., Renner, Ellen D., Akdis, Cezmi A.

Source: Allergy. 75(1):84-94

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111665461.0x000001&indx=1&recIds=ETOCvdc_100111665461.0x000001

Granulocyte-Macrophage Colony Stimulating Factor As an Indirect Mediator of Nociceptor Activation and Pain

Authors: Tewari, Damini, Cook, Andrew D., Lee, Ming-Chin, Christensen, Anne D., Croxford, Andrew, Becher, Burkhard, Poole, Daniel, Rajasekhar, Pradeep, Bunnett, Nigel, Smith, Julia E.

Source: Journal of neuroscience. 40(11):2189-2199

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN623653777&indx=1&recIds=ETOCRN623653777

Discovery of the Clinical Candidate IDOR-1117-2520: A Potent and Selective Antagonist of CCR6 for Autoimmune Diseases.

Authors: Meyer, Emmanuel A., Croxford, Andrew L., Gnerre, Carmela, Kulig, Paulina, Murphy, Mark J., Jacob, Elise M., Schäfer, Gabriel, Richard-Bildstein, Sylvia, Aissaoui, Hamed, Bouis, Patrick, Ertel, Eric A., de Kanter, Ruben, Keller, Marcel P., Lüthi, Urs, Caroff, Eva

Source: Journal of Medicinal Chemistry; 5/23/2024, Vol. 67 Issue 10, p8077-8098, 22p

GM-CSF in Neuroinflammation: Licensing Myeloid Cells for Tissue Damage

Authors: Croxford, Andrew L., Spath, Sabine, Becher, Burkhard

Source: In Trends in Immunology October 2015 36(10):651-662

The Cytokine GM-CSF Drives the Inflammatory Signature of CCR2+ Monocytes and Licenses Autoimmunity

Authors: Croxford, Andrew L., Lanzinger, Margit, Hartmann, Felix J., Schreiner, Bettina, Mair, Florian, Pelczar, Pawel, Clausen, Björn E., Jung, Steffen, Greter, Melanie, Becher, Burkhard

Source: In Immunity 15 September 2015 43(3):502-514

EBI2 Is Highly Expressed in Multiple Sclerosis Lesions and Promotes Early CNS Migration of Encephalitogenic CD4 T Cells

Authors: Wanke, Florian, Moos, Sonja, Croxford, Andrew L., Heinen, André P., Gräf, Stephanie, Kalt, Bettina, Tischner, Denise, Zhang, Juan, Christen, Isabelle, Bruttger, Julia, Yogev, Nir, Tang, Yilang, Zayoud, Morad, Israel, Nicole, Karram, Khalad, Reißig, Sonja, Lacher, Sonja M., Reichhold, Christian, Mufazalov, Ilgiz A., Ben-Nun, Avraham, Kuhlmann, Tanja, Wettschureck, Nina, Sailer, Andreas W., Rajewsky, Klaus, Casola, Stefano, Waisman, Ari, Kurschus, Florian C.

Source: Cell reports. 18(5):1270-1284

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100062383438.0x000001&indx=1&recIds=ETOCvdc_100062383438.0x000001

IL-12-and IL-23 in health and disease

Authors: Croxford, Andrew L., Kulig, Paulina, Becher, Burkhard

Source: In Cytokine and Growth Factor Reviews August 2014 25(4):415-421

IL-6 Regulates Neutrophil Microabscess Formation in IL-17A-Driven Psoriasiform Lesions

Authors: Croxford, Andrew L. ^*, Karbach, Susanne, Kurschus, Florian C., Wörtge, Simone, Nikolaev, Alexei, Yogev, Nir, Klebow, Sabrina, Schüler, Rebecca, Reissig, Sonja, Piotrowski, Carolin, Brylla, Elke, Bechmann, Ingo, Scheller, Jürgen, Rose-John, Stefan, Thomas Wunderlich, F., Münzel, Thomas, von Stebut, Esther, Waisman, Ari ^*

Source: In Journal of Investigative Dermatology March 2014 134(3):728-735

BAFF-secreting neutrophils drive plasma cell responses during emergency granulopoiesis

Authors: Parsa, Roham, Lund, Harald, Georgoudaki, Anna-Maria, Zhang, Xing-Mei, Guerreiro-Cacais, André Ortlieb, Grommisch, David, Warnecke, Andreas, Croxford, Andrew L., Jagodic, Maja, Becher, Burkhard

Source: Journal of experimental medicine. 213(8):1537-1554

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN607394554&indx=1&recIds=ETOCRN607394554

Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis

Authors: Penkava, Frank, Velasco-Herrera, Martin Del Castillo, Young, Matthew D., Yager, Nicole, Nwosu, Lilian N., Pratt, Arthur G., Lara, Alicia Lledo, Guzzo, Charlotte, Maroof, Ash, Mamanova, Lira, Cole, Suzanne, Efremova, Mirjana, Simone, Davide, Filer, Andrew, Brown, Chrysothemis C., Croxford, Andrew L., Isaacs, John D., Teichmann, Sarah, Bowness, Paul, Behjati, Sam, Hussein Al-Mossawi, M.

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174507088.0x000001&indx=1&recIds=ETOCvdc_100174507088.0x000001

IL-6 Controls Th17 Immunity in vivo by Inhibiting the Conversion of Conventional T Cells into Foxp3⁺ Regulatory T Cells

Authors: Korn, Thomas, Mitsdoerffer, Meike, Croxford, Andrew L., Awasthi, Amit, Dardalhon, Valérie A., Galileos, George, Vollmar, Patrick, Stritesky, Gretta L., Kaplan, Mark H., Waisman, Ari, Kuchroo, Vijay K., Oukka, Mohamed

Source: Proceedings of the National Academy of Sciences of the United States of America, 2008 Nov . 105(47), 18460-18465.

Access URL: https://www.jstor.org/stable/25465483

Mouse models for multiple sclerosis: Historical facts and future implications

Authors: Croxford, Andrew L., Kurschus, Florian C., Waisman, Ari

Source: In BBA - Molecular Basis of Disease 2011 1812(2):177-183

Interleukin 17 Drives Vascular Inflammation, Endothelial Dysfunction, and Arterial Hypertension in Psoriasis-Like Skin Disease

Authors: Karbach, Susanne, Croxford, Andrew L., Oelze, Matthias, Schüler, Rebecca, Minwegen, Daniel, Wegner, Joanna, Koukes, Lija, Yogev, Nir, Nikolaev, Alexei, Reißig, Sonja, Ullmann, Alexander, Knorr, Maike, Waldner, Maximilian, Neurath, Markus F., Li, Huige, Wu, Zhixiong, Brochhausen, Christoph, Scheller, Jürgen, Rose-John, Stefan, Piotrowski, Carolin, Bechmann, Ingo, Radsak, Markus, Wild, Philipp, Daiber, Andreas, von Stebut, Esther, Wenzel, Philip, Waisman, Ari, Münzel, Thomas

Source: Arteriosclerosis, thrombosis, and vascular biology. 34(12):2658-2668

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100030173024.0x000001&indx=1&recIds=ETOCvdc_100030173024.0x000001

Novel mouse models for use in IL-17A and Th17 research

Authors: Croxford, Andrew Lewis

Availability: http://data.europeana.eu/aggregation/europeana/2048441/item_2ZVVM3BUQJVECAPS4XH32FJZWCQW3DRH

Plaque-associated myeloid cells derive from resident microglia in an Alzheimer's disease model

Authors: Reed-Geaghan, Erin G., Croxford, Andrew L., Becher, Burkhard, Landreth, Gary E.

Source: Journal of experimental medicine. 217(4):e20191374-e20191374

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN624067897&indx=1&recIds=ETOCRN624067897

Cytokine reporter mice in immunological research: perspectives and lessons learned.

Authors: Croxford, Andrew L.^1,2, Buch, Thorsten^1,3

Source: Immunology. Jan2011, Vol. 132 Issue 1, p1-8. 8p.

Subject Terms: *CYTOKINES, *LABORATORY mice, *IMMUNE system, *CELLULAR immunity, *INTERLEUKIN-3, *MESSENGER RNA, *INTERLEUKIN-4

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