Human adaptation to immobilization: Novel insights of impacts on glucose disposal and fuel utilization

Authors: Shur, Natalie F., Simpson, Elizabeth J., Crossland, Hannah, Chivaka, Prince K., Constantin, Despina, Cordon, Sally M., Constantin‐Teodosiu, Dumitru, Stephens, Francis B., Lobo, Dileep N., Szewczyk, Nate, Narici, Marco, Prats, Clara, Macdonald, Ian A., Greenhaff, Paul L.

Source: Journal of cachexia, sarcopenia and muscle. 13(6):2999-3013

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175783899.0x000001&indx=1&recIds=ETOCvdc_100175783899.0x000001

Phenylbutyrate, a branched‐chain amino acid keto dehydrogenase activator, promotes branched‐chain amino acid metabolism and induces muscle catabolism in C2C12 cells

Authors: Crossland, Hannah, Smith, Kenneth, Idris, Iskandar, Phillips, Bethan E., Atherton, Philip J, Wilkinson, Daniel J

Source: Experimental physiology. 106(3):585-592

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100137345883.0x000001&indx=1&recIds=ETOCvdc_100137345883.0x000001

Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States

Authors: Stokes, Tanner, Timmons, James A., Crossland, Hannah, Tripp, Thomas R., Murphy, Kevin, McGlory, Chris, Mitchell, Cameron J., Oikawa, Sara Y., Morton, Robert W., Phillips, Bethan E., Baker, Steven K., Atherton, Phillip J., Wahlestedt, Claes, Phillips, Stuart M.

Source: In Cell Reports 4 August 2020 32(5)

A novel stable isotope tracer method to simultaneously quantify skeletal muscle protein synthesis and breakdown

Authors: Crossland, Hannah, Smith, Kenneth, Atherton, Philip J., Wilkinson, Daniel J.

Source: In Metabolism Open March 2020 5

Testosterone therapy induces molecular programming augmenting physiological adaptations to resistance exercise in older men

Authors: Gharahdaghi, Nima, Rudrappa, Supreeth, Brook, Matthew S., Idris, Iskandar, Crossland, Hannah, Hamrock, Claire, Abdul Aziz, Muhammad Hariz, Kadi, Fawzi, Tarum, Janelle, Greenhaff, Paul L., Constantin‐Teodosiu, Dumitru, Cegielski, Jessica, Phillips, Bethan E., Wilkinson, Daniel J., Szewczyk, Nathaniel J., Smith, Kenneth, Atherton, Philip J.

Source: Journal of cachexia, sarcopenia and muscle. 10(6):1276-1294

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100094328153.0x000001&indx=1&recIds=ETOCvdc_100094328153.0x000001

The impact of immobilisation and inflammation on the regulation of muscle mass and insulin resistance: different routes to similar end‐points

Authors: Crossland, Hannah, Skirrow, Sarah, Puthucheary, Zudin A., Constantin‐Teodosiu, Dumitru, Greenhaff, Paul L.

Source: Journal of physiology. 597(5):1259-1270

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100090622391.0x000001&indx=1&recIds=ETOCvdc_100090622391.0x000001

Gene-based analysis of angiogenesis, mitochondrial and insulin-related pathways in skeletal muscle of older individuals following nutraceutical supplementation

Authors: Crossland, Hannah, Pereira, Suzette L., Smith, Kenneth, Phillips, Bethan E., Atherton, Philip J.

Source: Journal of functional foods. 56:216-223

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100083133149.0x000001&indx=1&recIds=ETOCvdc_100083133149.0x000001

A statistical and biological response to an informatics appraisal of healthy aging gene signatures

Authors: Timmons, James, Gallagher, Iain, Sood, Sanjana, Phillips, Bethan, Crossland, Hannah, Howard, Robert, Kraus, William, Atherton, Philip

Source: Genome biology. 20(1):1-4

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191713303.0x000001&indx=1&recIds=ETOCvdc_100191713303.0x000001

Metabolomic and proteomic applications to exercise biomedicine.

Authors: Wilkinson, Daniel J., Crossland, Hannah, Atherton, Philip J.

Source: Translational Exercise Biomedicine; May2024, Vol. 1 Issue 1, p9-22, 14p

Subject Terms: METABOLOMICS, PROTEOMICS, MEDICAL research, EXERCISE, BIOMARKERS

Bed‐rest and exercise remobilization: Concurrent adaptations in muscle glucose and protein metabolism.

Authors: Shur, Natalie F., Simpson, Elizabeth J., Crossland, Hannah, Constantin, Despina, Cordon, Sally M., Constantin‐Teodosiu, Dumitru, Stephens, Francis B., Brook, Matthew S., Atherton, Philip J., Smith, Kenneth, Wilkinson, Daniel J., Mougin, Olivier E., Bradley, Christopher, Macdonald, Ian A., Greenhaff, Paul L.

Source: Journal of Cachexia, Sarcopenia & Muscle; Apr2024, Vol. 15 Issue 2, p603-614, 12p

The metabolic and molecular mechanisms of hyperammonaemia‐ and hyperethanolaemia‐induced protein catabolism in skeletal muscle cells

Authors: Crossland, Hannah, Smith, Kenneth, Atherton, Philip J., Wilkinson, Daniel J.

Source: Journal of cellular physiology. 233(12):9663-9673

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100087944044.0x000001&indx=1&recIds=ETOCvdc_100087944044.0x000001

Biomarkers of browning of white adipose tissue and their regulation during exercise- and diet-induced weight loss ,

Authors: Nakhuda, Asif, Josse, Andrea R, Gburcik, Valentina, Crossland, Hannah, Raymond, Frederic, Metairon, Sylviane, Good, Liam, Atherton, Philip J, Phillips, Stuart M, Timmons, James A ^*

Source: In The American Journal of Clinical Nutrition September 2016 104(3):557-565

A novel puromycin decorporation method to quantify skeletal muscle protein breakdown: A proof-of-concept study

Authors: Crossland, Hannah, Smith, Kenneth, Atherton, Philip J., Wilkinson, Daniel J.

Source: Biochemical and biophysical research communications. 494(3/4):608-614

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100061099932.0x000001&indx=1&recIds=ETOCvdc_100061099932.0x000001

A pilot study of alternative substrates in the critically Ill subject using a ketogenic feed.

Authors: McNelly, Angela, Langan, Anne, Bear, Danielle E., Page, Alexandria, Martin, Tim, Seidu, Fatima, Santos, Filipa, Rooney, Kieron, Liang, Kaifeng, Heales, Simon J., Baldwin, Tomas, Alldritt, Isabelle, Crossland, Hannah, Atherton, Philip J., Wilkinson, Daniel, Montgomery, Hugh, Prowle, John, Pearse, Rupert, Eaton, Simon, Puthucheary, Zudin A.

Source: Nature Communications; 12/15/2023, Vol. 14 Issue 1, p1-14, 14p

Subject Terms: CRITICALLY ill, INTENSIVE care units, PILOT projects, KETONES, AMINO acids

No Difference Between High-Fructose and High-Glucose Diets on Liver Triacylglycerol or Biochemistry in Healthy Overweight Men

Authors: Johnston, Richard D., Stephenson, Mary C., Crossland, Hannah, Cordon, Sally M., Palcidi, Elisa, Cox, Eleanor F., Taylor, Moira A., Aithal, Guruprasad P., Macdonald, Ian A.

Source: In Gastroenterology November 2013 145(5):1016-1025

Glucagon‐like peptide 1 infusions overcome anabolic resistance to feeding in older human muscle

Authors: Abdulla, Haitham, Phillips, Bethan E., Wilkinson, Daniel J., Limb, Marie, Jandova, Tereza, Bass, Joseph J., Rankin, Debbie, Cegielski, Jessica, Sayda, Mariwan, Crossland, Hannah, Williams, John P., Smith, Kenneth, Idris, Iskandar, Atherton, Philip J.

Source: Aging cell. 19(9)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108605916.0x000001&indx=1&recIds=ETOCvdc_100108605916.0x000001

A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status

Authors: Sood, Sanjana, Gallagher, Iain, Lunnon, Katie, Rullman, Eric, Keohane, Aoife, Crossland, Hannah, Phillips, Bethan, Cederholm, Tommy, Jensen, Thomas, van Loon, Luc, Lannfelt, Lars, Kraus, William, Atherton, Philip, Howard, Robert, Gustafsson, Thomas, Hodges, Angela, Timmons, James

Source: Genome biology. 16(1):1-17

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191713312.0x000001&indx=1&recIds=ETOCvdc_100191713312.0x000001

Longevity‐related molecular pathways are subject to midlife 'switch' in humans

Authors: Timmons, James A., Volmar, Claude‐Henry, Crossland, Hannah, Phillips, Bethan E., Sood, Sanjana, Janczura, Karolina J., Törmäkangas, Timo, Kujala, Urho M., Kraus, William E., Atherton, Philip J., Wahlestedt, Claes

Source: Aging cell. 18(4)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085001738.0x000001&indx=1&recIds=ETOCvdc_100085001738.0x000001

Metabolic and molecular responses of human patellar tendon to concentric- and eccentric-type exercise in youth and older age.

Authors: Crossland, Hannah, Brook, Matthew S., Quinlan, Jonathan I., Franchi, Martino V., Phillips, Bethan E., Wilkinson, Daniel J., Maganaris, Constantinos N., Greenhaff, Paul L., Szewczyk, Nathaniel J., Smith, Kenneth, Narici, Marco V., Atherton, Philip J.

Source: GeroScience; Feb2023, Vol. 45 Issue 1, p331-344, 14p

Subject Terms: PATELLAR tendon, EXERCISE for youth, YOUNG adults, OLDER people, PROTEIN synthesis, AGE groups, ISOMETRIC exercise, ISOKINETIC exercise

Targeted genotype analyses of GWAS-derived lean body mass and handgrip strength-associated single-nucleotide polymorphisms in elite master athletes.

Authors: Crossland, Hannah¹, Piasecki, Jessica², McCormick, Daniel¹, Phillips, Bethan E.¹, Wilkinson, Daniel J.¹, Smith, Kenneth¹, McPhee, Jamie S.³, Piasecki, Mathew¹, Atherton, Philip J.¹ Philip.Atherton@nottingham.ac.uk

Source: American Journal of Physiology: Regulatory, Integrative & Comparative Physiology. Aug2020, Vol. 319 Issue 2, pR184-R194. 11p.

Subject Terms: *SINGLE nucleotide polymorphisms, *LEAN body mass, *ELITE athletes, *BODY composition, *GENOTYPES, *ENDURANCE athletes