High expression of oleoyl-ACP hydrolase underpins life-threatening respiratory viral diseases

Authors: Jia, Xiaoxiao, Crawford, Jeremy Chase, Gebregzabher, Deborah, Monson, Ebony A., Mettelman, Robert C., Wan, Yanmin, Ren, Yanqin, Chou, Janet, Novak, Tanya, McQuilten, Hayley A., Clarke, Michele, Bachem, Annabell, Foo, Isabelle J., Fritzlar, Svenja, Carrera Montoya, Julio, Trenerry, Alice M., Nie, Shuai, Leeming, Michael G., Nguyen, Thi H.O., Kedzierski, Lukasz, Littler, Dene R., Kueh, Andrew, Cardamone, Tina, Wong, Chinn Yi, Hensen, Luca, Cabug, Aira, Laguna, Jaime Gómez, Agrawal, Mona, Flerlage, Tim, Boyd, David F., Van de Velde, Lee-Ann, Habel, Jennifer R., Loh, Liyen, Koay, Hui-Fern, van de Sandt, Carolien E., Konstantinov, Igor E., Berzins, Stuart P., Flanagan, Katie L., Wakim, Linda M., Herold, Marco J., Green, Amanda M., Smallwood, Heather S., Rossjohn, Jamie, Thwaites, Ryan S., Chiu, Christopher, Scott, Nichollas E., Mackenzie, Jason M., Bedoui, Sammy, Reading, Patrick C., Londrigan, Sarah L., Helbig, Karla J., Randolph, Adrienne G., Thomas, Paul G., Xu, Jianqing, Wang, Zhongfang, Chua, Brendon Y., Kedzierska, Katherine

Source: In Cell 22 August 2024 187(17):4586-4604

The interaction between RIPK1 and FADD controls perinatal lethality and inflammation

Authors: Rodriguez, Diego A., Tummers, Bart, Shaw, Jeremy J.P., Quarato, Giovanni, Weinlich, Ricardo, Cripps, James, Fitzgerald, Patrick, Janke, Laura J., Pelletier, Stephane, Crawford, Jeremy Chase, Green, Douglas R.

Source: In Cell Reports 25 June 2024 43(6)

Caspase-8 and FADD prevent spontaneous ZBP1 expression and necroptosis

Authors: Rodriguez, Diego A., Quarato, Giovanni, Liedmann, Swantje, Tummers, Bart, Zhang, Ting, Guy, Cliff, Crawford, Jeremy Chase, Palacios, Gustavo, Pelletier, Stephane, Kalkavan, Halime, Shaw, Jeremy J. P., Fitzgerald, Patrick, Chen, Mark J., Balachandran, Siddharth, Green, Douglas R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Oct 01. 119(41), 1-8.

Access URL: https://www.jstor.org/stable/27208796

DNAJB1-PRKACA fusion neoantigens elicit rare endogenous T cell responses that potentiate cell therapy for fibrolamellar carcinoma

Authors: Kirk, Allison M., Crawford, Jeremy Chase, Chou, Ching-Heng, Guy, Cliff, Pandey, Kirti, Kozlik, Tanya, Shah, Ravi K., Chung, Shanzou, Nguyen, Phuong, Zhang, Xiaoyu, Wang, Jin, Bell, Matthew, Mettelman, Robert C., Allen, E. Kaitlynn, Pogorelyy, Mikhail V., Kim, Hyunjin, Minervina, Anastasia A., Awad, Walid, Bajracharya, Resha, White, Toni, Long, Donald, Jr., Gordon, Brittney, Morrison, Michelle, Glazer, Evan S., Murphy, Andrew J., Jiang, Yixing, Fitzpatrick, Elizabeth A., Yarchoan, Mark, Sethupathy, Praveen, Croft, Nathan P., Purcell, Anthony W., Federico, Sara M., Stewart, Elizabeth, Gottschalk, Stephen, Zamora, Anthony E., DeRenzo, Christopher, Strome, Scott E., Thomas, Paul G.

Source: In Cell Reports Medicine 19 March 2024 5(3)

Indoleamine 2,3-dioxygenase 1 regulates cell permissivity to astrovirus infection

Authors: Cortez, Valerie, Livingston, Brandi, Sharp, Bridgett, Hargest, Virginia, Papizan, James B., Pedicino, Natalie, Lanning, Sarah, Jordan, Summer Vaughn, Gulman, Jacob, Vogel, Peter, DuBois, Rebecca M., Crawford, Jeremy Chase, Boyd, David F., Pruett-Miller, Shondra M., Thomas, Paul G., Schultz-Cherry, Stacey

Source: In Mucosal Immunology August 2023 16(4):551-562

DRAK2 contributes to type 1 diabetes by negatively regulating IL-2 sensitivity to alter regulatory T cell development

Authors: Mandarano, Alexandra H., Harris, Tarsha L., Creasy, Blaine M., Wehenkel, Marie, Duggar, Marygrace, Wilander, Benjamin A., Mishra, Ashutosh, Crawford, Jeremy Chase, Mullen, Sarah A., Williams, Katherine M., Pillai, Meenu, High, Anthony A., McGargill, Maureen A.

Source: In Cell Reports 28 February 2023 42(2)

IL-13/IL-4 signaling contributes to fibrotic progression of the myeloproliferative neoplasms

Authors: Melo-Cardenas, Johanna, Bezavada, Lavanya, Crawford, Jeremy Chase, Gurbuxani, Sandeep, Cotton, Anitria, Kang, Guolian, Gossett, Jeffrey, Marinaccio, Christian, Weinberg, Rona, Hoffman, Ronald, Migliaccio, Anna Rita, Zheng, Yan, Derecka, Marta, Rinaldi, Ciro R., Crispino, John D.

Source: In Blood 29 December 2022 140(26):2805-2817

Engineering naturally occurring CD7− T cells for the immunotherapy of hematological malignancies

Authors: Freiwan, Abdullah, Zoine, Jaquelyn T., Crawford, Jeremy Chase, Vaidya, Abishek, Schattgen, Stefan A., Myers, Jacquelyn A., Patil, Sagar L., Khanlari, Mahsa, Inaba, Hiroto, Klco, Jeffery M., Mullighan, Charles G., Krenciute, Giedre, Chockley, Peter J., Naik, Swati, Langfitt, Deanna M., Mamonkin, Maksim, Obeng, Esther A., Thomas, Paul G., Gottschalk, Stephen, Velasquez, M. Paulina ^∗

Source: In Blood 22 December 2022 140(25):2684-2696

Preferential expansion of CD8+ CD19-CAR T cells postinfusion and the role of disease burden on outcome in pediatric B-ALL

Authors: Talleur, Aimee C., Qudeimat, Amr, Métais, Jean-Yves, Langfitt, Deanna, Mamcarz, Ewelina, Crawford, Jeremy Chase, Huang, Sujuan, Cheng, Cheng, Hurley, Caitlin, Madden, Renee, Sharma, Akshay, Suliman, Ali, Srinivasan, Ashok, Velasquez, M. Paulina, Obeng, Esther A., Willis, Catherine, Akel, Salem, Karol, Seth E., Inaba, Hiroto, Bragg, Allison, Zheng, Wenting, Zhou, Sheng M., Schell, Sarah, Tuggle-Brown, MaCal, Cullins, David, Patil, Sagar L, Li, Ying, Thomas, Paul G., Zebley, Caitlin, Youngblood, Benjamin, Pui, Ching-Hon, Lockey, Timothy, Geiger, Terrence L., Meagher, Michael M., Triplett, Brandon M., Gottschalk, Stephen

Source: In Blood Advances 8 November 2022 6(21):5737-5749

SARS-CoV-2-specific T cell memory with common TCRαβ motifs is established in unvaccinated children who seroconvert after infection

Authors: Rowntree, Louise C., Nguyen, Thi H.O., Kedzierski, Lukasz, Neeland, Melanie R., Petersen, Jan, Crawford, Jeremy Chase, Allen, Lilith F., Clemens, E. Bridie, Chua, Brendon, McQuilten, Hayley A., Minervina, Anastasia A., Pogorelyy, Mikhail V., Chaurasia, Priyanka, Tan, Hyon-Xhi, Wheatley, Adam K., Jia, Xiaoxiao, Amanat, Fatima, Krammer, Florian, Allen, E. Kaitlynn, Sonda, Sabrina, Flanagan, Katie L., Jumarang, Jaycee, Pannaraj, Pia S., Licciardi, Paul V., Kent, Stephen J., Bond, Katherine A., Williamson, Deborah A., Rossjohn, Jamie, Thomas, Paul G., Tosif, Shidan, Crawford, Nigel W., van de Sandt, Carolien E., Kedzierska, Katherine

Source: In Immunity 12 July 2022 55(7):1299-1315

Localization of a TORC1-eIF4F translation complex during CD8+ T cell activation drives divergent cell fate

Authors: Liedmann, Swantje, Liu, Xueyan, Guy, Clifford S., Crawford, Jeremy Chase, Rodriguez, Diego A., Kuzuoğlu-Öztürk, Duygu, Guo, Ao, Verbist, Katherine C., Temirov, Jamshid, Chen, Mark J., Ruggero, Davide, Zhang, Hui, Thomas, Paul G., Green, Douglas R.

Source: In Molecular Cell 7 July 2022 82(13):2401-2414

Induction of broadly reactive influenza antibodies increases susceptibility to autoimmunity

Authors: Labombarde, Jocelyn G., Pillai, Meenu R., Wehenkel, Marie, Lin, Chun-Yang, Keating, Rachael, Brown, Scott A., Crawford, Jeremy Chase, Brice, David C., Castellaw, Ashley H., Mandarano, Alexandra H., Guy, Clifford S., Mejia, Juan R., Lewis, Carlessia D., Chang, Ti-Cheng, Oshansky, Christine M., Wong, Sook-San, Webby, Richard J., Yan, Mei, Li, Quan–Zhen, Marion, Tony N., Thomas, Paul G., McGargill, Maureen A.

Source: In Cell Reports 8 March 2022 38(10)

SARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans

Authors: Estepp, Jeremie H., Schultz-Cherry, Stacey, McGargill, Maureen A., Gaur, Aditya, Hoffman, James, Mori, Motomi, Tang, Li, Tuomanen, Elaine, Webby, Richard, Hayden, Randall T., Hakim, Hana, Hijano, Diego R., Allison, Kim J., Allen, E. Kaitlynn, Bajracharya, Resha, Awad, Walid, Van de Velde, Lee-Ann, Clark, Brandi L., Wilson, Taylor L., Souquette, Aisha, Castellaw, Ashley, Dallas, Ronald H., Gowen, Ashleigh, Fabrizio, Thomas P., Lin, Chun-Yang, Brice, David C., Cherry, Sean, Roubidoux, Ericka Kirkpatrick, Cortez, Valerie, Freiden, Pamela, Wohlgemuth, Nicholas, Whitt, Kendall, Mudd, Philip A., Minervina, Anastasia A., Pogorelyy, Mikhail V., Turner, Jackson S., Kim, Wooseob, Kalaidina, Elizaveta, Petersen, Jan, Schmitz, Aaron J., Lei, Tingting, Haile, Alem, Kirk, Allison M., Mettelman, Robert C., Crawford, Jeremy Chase, Nguyen, Thi H.O., Rowntree, Louise C., Rosati, Elisa, Richards, Katherine A., Sant, Andrea J., Klebert, Michael K., Suessen, Teresa, Middleton, William D., Wolf, Joshua, Teefey, Sharlene A., O’Halloran, Jane A., Presti, Rachel M., Kedzierska, Katherine, Rossjohn, Jamie, Thomas, Paul G., Ellebedy, Ali H.

Source: In Cell 17 February 2022 185(4):603-613

Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response

Authors: Gaur, Aditya H., Hoffman, James M., Mori, Tomi, Tuomanen, Elaine I., Webby, Richard J., Hakim, Hana, Hayden, Randall T., Hijano, Diego R., Awad, Walid, Bajracharya, Resha, Clark, Brandi L., Cortez, Valerie, Dallas, Ronald H., Fabrizio, Thomas, Freiden, Pamela, Gowen, Ashleigh, Hodges, Jason, Kirk, Allison M., Roubidoux, Ericka Kirkpatrick, Mettelman, Robert C., Russell-Bell, Jamie, Souquette, Aisha, Sparks, James, Van de Velde, Lee-Ann, Vazquez-Pagan, Ana, Whitt, Kendall, Wilson, Taylor L., Wittman, David E., Wohlgemuth, Nicholas, Wu, Gang, Lin, Chun-Yang, Wolf, Joshua, Brice, David C., Sun, Yilun, Locke, Macauley, Cherry, Sean, Castellaw, Ashley H., Wehenkel, Marie, Crawford, Jeremy Chase, Zarnitsyna, Veronika I., Duque, Daniel, Allison, Kim J., Allen, E. Kaitlynn, Brown, Scott A., Mandarano, Alexandra H., Estepp, Jeremie H., Taylor, Charles, Molina-Paris, Carmen, Schultz-Cherry, Stacey, Tang, Li, Thomas, Paul G., McGargill, Maureen A.

Source: In Cell Host & Microbe 12 January 2022 30(1):83-96

Non-terminally exhausted tumor-resident memory HBV-specific T cell responses correlate with relapse-free survival in hepatocellular carcinoma

Authors: Cheng, Yang, Gunasegaran, Bavani, Singh, Harsimran D., Dutertre, Charles-Antoine, Loh, Chiew Yee, Lim, Jia Qi, Crawford, Jeremy Chase, Lee, Hong Kai, Zhang, Xiaomeng, Lee, Bernett, Becht, Etienne, Lim, Wan Jun, Yeong, Joe, Chan, Chung Yip, Chung, Alexander, Goh, Brian K.P., Chow, Pierce K.H., Chan, Jerry K.Y., Ginhoux, Florent, Tai, David, Chen, Jinmiao, Lim, Seng Gee, Zhai, Weiwei, Choo, Su Pin, Newell, Evan W.

Source: In Immunity 10 August 2021 54(8):1825-1840

CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope display high naive precursor frequency and TCR promiscuity

Authors: Nguyen, Thi H.O., Rowntree, Louise C., Petersen, Jan, Chua, Brendon Y., Hensen, Luca, Kedzierski, Lukasz, van de Sandt, Carolien E., Chaurasia, Priyanka, Tan, Hyon-Xhi, Habel, Jennifer R., Zhang, Wuji, Allen, Lilith F., Earnest, Linda, Mak, Kai Yan, Juno, Jennifer A., Wragg, Kathleen, Mordant, Francesca L., Amanat, Fatima, Krammer, Florian, Mifsud, Nicole A., Doolan, Denise L., Flanagan, Katie L., Sonda, Sabrina, Kaur, Jasveen, Wakim, Linda M., Westall, Glen P., James, Fiona, Mouhtouris, Effie, Gordon, Claire L., Holmes, Natasha E., Smibert, Olivia C., Trubiano, Jason A., Cheng, Allen C., Harcourt, Peter, Clifton, Patrick, Crawford, Jeremy Chase, Thomas, Paul G., Wheatley, Adam K., Kent, Stephen J., Rossjohn, Jamie, Torresi, Joseph, Kedzierska, Katherine

Source: In Immunity 11 May 2021 54(5):1066-1082

Tumor-intrinsic and -extrinsic determinants of response to blinatumomab in adults with B-ALL

Authors: Zhao, Yaqi ^*, Aldoss, Ibrahim ^*, Qu, Chunxu ^*, Crawford, Jeremy Chase, Gu, Zhaohui, Allen, Emma K., Zamora, Anthony E., Alexander, Thomas B., Wang, Jeremy, Goto, Hiroaki, Imamura, Toshihiko, Akahane, Koshi, Marcucci, Guido, Stein, Anthony S., Bhatia, Ravi, Thomas, Paul G., Forman, Stephen J., Mullighan, Charles G. ^*, Roberts, Kathryn G. ^{†, *}

Source: In Blood 28 January 2021 137(4):471-484

Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis

Authors: Tummers, Bart, Mari, Luigi, Guy, Clifford S., Heckmann, Bradlee L., Rodriguez, Diego A., Rühl, Sebastian, Moretti, Julien, Crawford, Jeremy Chase, Fitzgerald, Patrick, Kanneganti, Thirumala-Devi, Janke, Laura J., Pelletier, Stephane, Blander, J. Magarian, Green, Douglas R.

Source: In Immunity 16 June 2020 52(6):994-1006

Influenza Virus Z-RNAs Induce ZBP1-Mediated Necroptosis

Authors: Zhang, Ting, Yin, Chaoran, Boyd, David F., Quarato, Giovanni, Ingram, Justin P., Shubina, Maria, Ragan, Katherine B., Ishizuka, Takumi, Crawford, Jeremy Chase, Tummers, Bart, Rodriguez, Diego A., Xue, Jia, Peri, Suraj, Kaiser, William J., López, Carolina B., Xu, Yan, Upton, Jason W., Thomas, Paul G., Green, Douglas R., Balachandran, Siddharth

Source: In Cell 19 March 2020 180(6):1115-1129

Selected before selection: A case for inherent antigen bias in the T-cell receptor repertoire

Authors: Thomas, Paul G., Crawford, Jeremy Chase

Source: In Current Opinion in Systems Biology December 2019 18:36-43