Randomised clinical trial: Bifidobacterium lactis NCC2818 probiotic vs placebo, and impact on gut transit time, symptoms, and gut microbiology in chronic constipation

Authors: Dimidi, Eirini, Zdanaviciene, Ausra, Christodoulides, Stephanos, Taheri, Shiva, Louis, Petra, Duncan, Peter I., Emami, Nashmil, Crabbé, Rafael, De Castro, C. Antonio, McLean, Peter, Bergonzelli, Gabriela E., Whelan, Kevin, Mark Scott, S.

Source: Alimentary pharmacology & therapeutics. 49(3):251-264

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085007648.0x000001&indx=1&recIds=ETOCvdc_100085007648.0x000001

Long-Term Prophylactic Treatment with Oral Deucrictibant Improves Health-Related Quality of Life of Patients with Hereditary Angioedema: CHAPTER-1 Open-Label Extension Study

Authors: Anderson, John ¹, Arcoleo, Francesco ^▪▪▪, Aygören-Pürsün, Emel ³, Cancian, Mauro ⁴, Chapdelaine, Hugo ⁵, Conlon, Niall ⁶, Eren, Efrem ^▪▪▪, Gompels, Mark ⁸, Grigoriadou, Sofia ⁹, Guarino, Maria ¹⁰, Gurugama, Padmalal ¹¹, Kinaciyan, Tamar ¹², Magerl, Markus ¹³, Manning, Michael ^▪▪▪, Stobiecki, Marcin ¹⁵, Tarzi, Michael ¹⁶, Valerieva, Anna ¹⁷, Wedner, H. James ¹⁸, Yang, William ¹⁹, Zanichelli, Andrea ²⁰, Crabbé, Rafael ²¹, Mulders, Susan ²², Levy, Jonathan ²³, Freudensprung, Ulrich ²⁴, Katbeh, Umar ²⁴, Knolle, Jochen ²⁵, Lesage, Anne ²⁶, Lu, Peng ²³, Riedl, Marc ²⁷

Source: In The Journal of Allergy and Clinical Immunology February 2025 155(2) Supplement:AB198-AB198

Long-Term Safety and Efficacy of Oral Deucrictibant for Prophylaxis in Hereditary Angioedema: Results of the CHAPTER-1 Open-Label Extension Study

Authors: Riedl, Marc ¹, Anderson, John ², Arcoleo, Francesco ³, Cancian, Mauro ⁴, Chapdelaine, Hugo ⁵, Conlon, Niall ⁶, Eren, Efrem ⁷, Gompels, Mark ⁸, Grigoriadou, Sofia ⁹, Guarino, Maria ¹⁰, Gurugama, Padmalal ¹¹, Kinaciyan, Tamar ¹², Magerl, Markus ¹³, Manning, Michael ¹⁴, Stobiecki, Marcin ¹⁵, Tarzi, Michael ¹⁶, Valerieva, Anna ¹⁷, Wedner, H. James ¹⁸, Yang, William ¹⁹, Zanichelli, Andrea ²⁰, Crabbé, Rafael ²¹, Mulders, Susan ²², Levy, Jonathan ²³, Freudensprung, Ulrich ²⁴, Katbeh, Umar ²⁴, Knolle, Jochen ²⁵, Lesage, Anne ²⁶, Lu, Peng ²³, Aygören-Pürsün, Emel ²⁷

Source: In The Journal of Allergy and Clinical Immunology February 2025 155(2) Supplement:AB194-AB194

Efficacy And Safety Of Bradykinin B2 Receptor Inhibition With Oral PHVS416 In Treating Hereditary Angioedema Attacks: Results Of RAPIDe-1 Phase 2 Trial

Authors: Maurer, Marcus, Anderson, John, Aygören-Pürsün, Emel, Bouillet, Laurence, Baeza, María Luisa, Chapdelaine, Hugo, Cohn, Danny, Du-Thanh, Aurélie, Fain, Olivier, Farkas, Henriette, Greve, Jens, Guilarte, Mar, Hagin, David, Hakl, Roman, Jacobs, Joshua, Kessell, Aharon, Kiani-Alikhan, Sorena, Králíčková, Pavlína, Li, Huamin, Bellfill, Ramon Lleonart, Magerl, Markus, Manning, Michael, Reshef, Avner, Ritchie, Bruce, Spadaro, Giuseppe, Staevska, Maria, Staubach, Petra, Stobiecki, Marcin, Sussman, Gordon, Tarzi, Michael, Valerieva, Anna, Yang, William, Jouvin, Marie-Helene, Crabbé, Rafael, van Leeuwen, Simone, Chen, Huaihou, Zhu, Li, Knolle, Jochen, Lesage, Anne, Lu, Peng, Riedl, Marc

Source: Journal of allergy and clinical immunology. 151(2):AB134-AB134

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100180527062.0x000001&indx=1&recIds=ETOCvdc_100180527062.0x000001

Efficacy And Safety Of Bradykinin B2 Receptor Antagonism With Oral Deucrictibant In Prophylaxis Of Hereditary Angioedema Attacks: Results Of CHAPTER-1 Phase 2 Trial

Authors: Riedl, Marc, Anderson, John, Arcoleo, Francesco, Cancian, Mauro, Chapdelaine, Hugo, Conlon, Niall, Eren, Efrem, Gompels, Mark, Grigoriadou, Sofia, Guarino, Maria, Gurugama, Padmalal, Kinaciyan, Tamar, Magerl, Markus, Manning, Michael, Stobiecki, Marcin, Tarzi, Michael, Valerieva, Anna, Wedner, H. James, Yang, William, Zanichelli, Andrea, Crabbe, Rafael, Mulders, Susan, Royston, Minying, Zhu, Li, Knolle, Jochen, Lesage, Anne, Lu, Peng, Aygören-Pürsün, Emel

Source: In The Journal of Allergy and Clinical Immunology February 2024 153(2) Supplement:AB11-AB11

Cycloundecadepsipeptide compounds and use of said compounds as a medicament

CYCLOUNDECADEPSIPEPTIDE COMPOUNDS AND USE OF SAID COMPOUNDS AS A MEDICAMENT

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