HBV serum RNA kinetics during nucleic acid polymers based therapy predict functional cure

Authors: Hershkovich, Leeor ^a, Cotler, Scott J. ^a, Shekhtman, Louis ^{a, b}, Bazinet, Michel ^c, Anderson, Mark ^d, Kuhns, Mary ^d, Cloherty, Gavin ^d, Vaillant, Andrew ^{c, ⁎⁎}, Dahari, Harel ^{a, ⁎}

Source: In Antiviral Research February 2025 234

Multi-Objective Model Exploration of Hepatitis C Elimination in an Agent-Based Model of People who Inject Drugs

Authors: Tatara, Eric, Collier, Nicholson T., Ozik, Jonathan, Gutfraind, Alexander, Cotler, Scott J., Dahari, Harel, Major, Marian, Boodram, Basmattee

Source: 2019 Winter Simulation Conference (WSC) Winter Simulation Conference (WSC), 2019. :1008-1019 Dec, 2019

Relation: 2019 Winter Simulation Conference (WSC)

Modelling HDV kinetics under the entry inhibitor bulevirtide suggests the existence of two HDV-infected cell populations

Authors: Shekhtman, Louis, Cotler, Scott J., Degasperi, Elisabetta, Anolli, Maria Paola, Uceda Renteria, Sara Colonia, Sambarino, Dana, Borghi, Marta, Perbellini, Riccardo, Facchetti, Floriana, Ceriotti, Ferruccio, Lampertico, Pietro, Dahari, Harel

Source: In JHEP Reports February 2024 6(2)

Treatment of chronic hepatitis D with peginterferon lambda—the phase 2 LIMT-1 clinical trial

Authors: Etzion, Ohad, Hamid, Saeed, Lurie, Yoav, Gane, Edward J., Yardeni, David, Duehren, Sarah, Bader, Nimrah, Nevo-Shor, Anat, Channa, Saleh Muhammad, Cotler, Scott J., Mawani, Minaz, Parkash, Om, Dahari, Harel, Choong, Ingrid, Glenn, Jeffrey S.

Source: Hepatology. 77(6):2093-2103

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191135680.0x000001&indx=1&recIds=ETOCvdc_100191135680.0x000001

Inhibition of Abelson Tyrosine-Protein Kinase 2 Suppresses the Development of Alcohol-Associated Liver Disease by Decreasing PPARgamma Expression

Authors: Malnassy, Greg, Keating, Claudia R., Gad, Shaimaa, Bridgeman, Bryan, Perera, Aldeb, Hou, Wei, Cotler, Scott J., Ding, Xianzhong, Choudhry, Mashkoor, Sun, Zhaoli, Koleske, Anthony J., Qiu, Wei

Source: In Cellular and Molecular Gastroenterology and Hepatology 2023 16(5):685-709

Integrin subunit beta 8 contributes to lenvatinib resistance in HCC

Authors: Hou, Wei, Bridgeman, Bryan, Malnassy, Greg, Ding, Xianzhong, Cotler, Scott J., Dhanarajan, Asha, Qiu, Wei

Source: Hepatology communications. 6(7):1786-1802

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154052176.0x000001&indx=1&recIds=ETOCvdc_100154052176.0x000001

Combined Use of Aspirin and Statin is Associated With a Decreased Incidence of Hepatocellular Carcinoma

Authors: Singh, Jasleen, Wozniak, Amy, Cotler, Scott J., Dhanarajan, Asha, Aldrich, Daniel, Park, David, Kasia, Chris, Schmidt, Benjamin, Scaglione, Steven

Source: Journal of clinical gastroenterology. 56(4):369-373

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100146561899.0x000001&indx=1&recIds=ETOCvdc_100146561899.0x000001

Machine learning for mathematical models of HCV kinetics during antiviral therapy

Authors: Churkin, Alexander, Kriss, Stephanie, Uziel, Asher, Goyal, Ashish, Zakh, Rami, Cotler, Scott J., Etzion, Ohad, Shlomai, Amir, Rotstein, Horacio G., Dahari, Harel, Barash, Danny

Source: In Mathematical Biosciences January 2022 343

Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling

Authors: Wang, Hao, Hou, Wei, Perera, Aldeb, Bettler, Carlee, Beach, Jordan R., Ding, Xianzhong, Li, Jun, Denning, Mitchell F., Dhanarajan, Asha, Cotler, Scott J., Joyce, Cara, Yin, Jun, Ahmed, Fowsiyo, Roberts, Lewis R., Qiu, Wei

Source: In Cell Reports 23 February 2021 34(8)

Theoretical modeling of hepatitis C acute infection in liver-humanized mice support pre-clinical assessment of candidate viruses for controlled-human-infection studies.

Authors: Shi, Zhenzhen, Mhlanga, Adquate, Ishida, Yuji, Josephson, Ari, Collier, Nicholson T., Abe-Chayama, Hiromi, Tateno-Mukaidani, Chise, Cotler, Scott J., Ozik, Jonathan, Major, Marian, Feld, Jordan J., Chayama, Kazuaki, Dahari, Harel

Source: Scientific Reports; 12/30/2024, Vol. 14 Issue 1, p1-12, 12p

Subject Terms: HEPATITIS C, MEDICAL sciences, MEDICAL microbiology, HEPATITIS C virus, ORDINARY differential equations

Modeling based response guided therapy in subjects with recent hepatitis C infection

Authors: Gorstein, Evan, Martinello, Marianne, Churkin, Alexander, Dasgupta, Swikriti, Walsh, Kevin, Applegate, Tanya L., Yardeni, David, Etzion, Ohad, Uprichard, Susan L., Barash, Danny, Cotler, Scott J., Matthews, Gail V., Dahari, Harel

Source: In Antiviral Research August 2020 180

ABL1, Overexpressed in Hepatocellular Carcinomas, Regulates Expression of NOTCH1 and Promotes Development of Liver Tumors in Mice

Authors: Wang, Fang, Hou, Wei, Chitsike, Lennox, Xu, Yingchen, Bettler, Carlee, Perera, Aldeb, Bank, Thomas, Cotler, Scott J., Dhanarajan, Asha, Denning, Mitchell F., Ding, Xianzhong, Breslin, Peter, Qiang, Wenan, Li, Jun, Koleske, Anthony J., Qiu, Wei

Source: In Gastroenterology July 2020 159(1):289-305

Mathematical modeling suggests that entry-inhibitor bulevirtide may interfere with hepatitis D virus clearance from circulation

Authors: Shekhtman, Louis, Cotler, Scott J., Ploss, Alexander, Dahari, Harel

Source: Journal of hepatology. 76(5):1229-1231

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179671490.0x000001&indx=1&recIds=ETOCvdc_100179671490.0x000001

Modeling challenges of hepatitis D virus kinetics during bulevirtide-based therapy

Authors: Mhlanga, Adquate ¹, Wasserman, Ori ¹, Lampertico, Pietro ^{2, 3}, Cotler, Scott J. ¹, Dahari, Harel ^{1, ⁎}

Source: In JHEP Reports February 2025 7(2)

American Ancestry Is a Risk Factor for Suspected Nonalcoholic Fatty Liver Disease in Hispanic/Latino Adults

Authors: Kallwitz, Eric R., Tayo, Bamidele O., Kuniholm, Mark H., Cai, Jianwen, Daviglus, Martha, Cooper, Richard S., Cotler, Scott J.

Source: In Clinical Gastroenterology and Hepatology October 2019 17(11):2301-2309

Objectively measured sedentary time, physical activity and liver enzyme elevations in US Hispanics/Latinos

Authors: Li, Jun, Hua, Simin, Chen, Guo‐Chong, Strizich, Garrett, Kuniholm, Mark H., Shan, Zhilei, Talavera, Gregory A., Castañeda, Sheila F., Gellman, Marc D., Cai, Jianwen, Cotler, Scott J., Zhang, Xuehong, Hu, Frank B., Kaplan, Robert, Isasi, Carmen R., Qi, Qibin

Source: Liver international. 40(8):1883-1894

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108145559.0x000001&indx=1&recIds=ETOCvdc_100108145559.0x000001

Association of HSD17B13 rs72613567:TA with non‐alcoholic fatty liver disease in Hispanics/Latinos

Authors: Kallwitz, Eric, Tayo, Bamidele O., Kuniholm, Mark H., Daviglus, Martha, Zeng, Donglin, Isasi, Carmen R., Cotler, Scott J.

Source: Liver international. 40(4):889-893

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100106940140.0x000001&indx=1&recIds=ETOCvdc_100106940140.0x000001

Barriers to treatment of chronic hepatitis C with direct acting antivirals in an urban clinic

Authors: Malespin, Miguel, Harris, Ciel, Kanar, Ozdemir, Jackman, Kelly, Smotherman, Carmen, Johnston, Abbey, Ferm, Julie, de Melo, Silvio W., Jr, Scolapio, James S., Nelson, David R., Cotler, Scott J.

Source: In Annals of Hepatology March-April 2019 18(2):304-309

A randomized, proof-of-concept clinical trial on repurposing chlorcyclizine for the treatment of chronic hepatitis C

Authors: Koh, Christopher, Dubey, Preeti, Han, Ma Ai Thanda, Walter, Peter J., Garraffo, H. Martin, Surana, Pallavi, Southall, Noel T., Borochov, Nathaniel, Uprichard, Susan L., Cotler, Scott J., Etzion, Ohad, Heller, Theo, Dahari, Harel, Liang, T. Jake

Source: In Antiviral Research March 2019 163:149-155

Interferon alpha induces a stronger antiviral effect than interferon lambda in HBV/HDV infected humanized mice

Authors: Duehren, Sarah, Uchida, Takuro, Tsuge, Masataka, Hiraga, Nobuhiko, Uprichard, Susan L., Etzion, Ohad, Glenn, Jeffrey, Koh, Christopher, Heller, Theo, Cotler, Scott J., Oka, Shiro, Chayama, Kazuaki, Dahari, Harel

Source: In Virus Research November 2024 349