Genetic dissection of Nodal and Bmp signalling requirements during primordial germ cell development in mouse

Authors: Senft, Anna, Bikoff, Elizabeth, Robertson, Elizabeth, Costello, Ita

Source: Nature communications. 10(1):1-11

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125967238.0x000001&indx=1&recIds=ETOCvdc_100125967238.0x000001

A degron-based approach to manipulate Eomes functions in the context of the developing mouse embryo.

Authors: Bisia, Alexandra M.¹, Costello, Ita¹, Xypolita, Maria-Eleni¹, Harland, Luke T. G.¹, Kurbel, Philipp J.¹, Bikoff, Elizabeth K.¹, Robertson, Elizabeth J.¹ elizabeth.robertson@path.ox.ac.uk

Source: Proceedings of the National Academy of Sciences of the United States of America. 10/31/2023, Vol. 120 Issue 44, p1-10. 24p.

Subject Terms: *YOLK sac, *EMBRYO implantation, *EMBRYOS, *EPITHELIAL-mesenchymal transition, *EMBRYONIC stem cells

The transcriptional repressor Blimp1/PRDM1 regulates the maternal decidual response in mice

Authors: Goolam, Mubeen, Xypolita, Maria-Eleni, Costello, Ita, Lydon, John P., DeMayo, Francesco J., Bikoff, Elizabeth K., Robertson, Elizabeth J., Mould, Arne W.

Source: Nature communications. 11(1)

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Lhx1 functions together with Otx2, Foxa2, and Ldb1 to govern anterior mesendoderm, node, and midline development

Authors: Costello, Ita, Nowotschin, Sonja, Sun, Xin, Mould, Arne W., Hadjantonakis, Anna-Katerina, Bikoff, Elizabeth K., Robertson, Elizabeth J.

Source: Genes & development. 29(20):2108-2122

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NuRD Suppresses Pluripotency Gene Expression to Promote Transcriptional Heterogeneity and Lineage Commitment

Authors: Reynolds, Nicola, Latos, Paulina, Hynes-Allen, Antony, Loos, Remco, Leaford, Donna, O'Shaughnessy, Aoife, Mosaku, Olukunbi, Signolet, Jason, Brennecke, Philip, Kalkan, Tüzer, Costello, Ita, Humphreys, Peter, Mansfield, William, Nakagawa, Kentaro, Strouboulis, John, Behrens, Axel, Bertone, Paul, Hendrich, Brian

Source: In Cell Stem Cell 4 May 2012 10(5):583-594

Keeping things quiet: Roles of NuRD and Sin3 co-repressor complexes during mammalian development

Authors: McDonel, Patrick, Costello, Ita, Hendrich, Brian

Source: In International Journal of Biochemistry and Cell Biology 2009 41(1):108-116

Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming

Authors: Senft, Anna D., Costello, Ita, King, Hamish W., Mould, Arne W., Bikoff, Elizabeth K., Robertson, Elizabeth J.

Source: Cell reports. 24(8):1977-1985.e7

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111519725.0x000001&indx=1&recIds=ETOCvdc_100111519725.0x000001

2018 – EOMESODERMIN GOVERNS THE HEMOGENIC COMPETENCE OF MURINE YOLK-SAC MESODERMAL PROGENITORS

Authors: Harland, Luke, Simon, Claire, Senft, Anna, Costello, Ita, Greder, Lucas, Imaz-Rosshandler, Ivan, Gottgens, Berthold, Marioni, John, Bikoff, Elizabeth, Porcher, Catherine, de Bruijn, Marella, Robertson, Elizabeth

Source: Experimental hematology. 88(S):S34-S34

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The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation.

Authors: Costello, Ita¹, Pimeisl, Inga-Marie², Dräger, Sarah², Bikoff, Elizabeth K.¹, Robertson, Elizabeth J.¹, Arnold, Sebastian J.²

Source: Nature Cell Biology. Sep2011, Vol. 13 Issue 9, p1084-1091. 8p. 1 Color Photograph, 2 Diagrams, 2 Graphs.

Subject Terms: *GENETIC transformation, *TRANSCRIPTION factors, *LABORATORY mice, *CELL lines, *GASTRULATION, *EPITHELIAL cells

The T-box transcription factor Eomesodermin governs haemogenic competence of yolk sac mesodermal progenitors

Authors: Harland, Luke T. G., Simon, Claire S., Senft, Anna D., Costello, Ita, Greder, Lucas, Imaz-Rosshandler, Ivan, Göttgens, Berthold, Marioni, John C., Bikoff, Elizabeth K., Porcher, Catherine, de Bruijn, Marella F. T. R., Robertson, Elizabeth J.

Source: Nature Cell Biology; January 2021, Vol. 23 Issue: 1 p61-74, 14p

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Transcriptional networks regulating cell allocation in the post-implantation mouse embryo

Authors: Costello, Ita, Simon, Claire, Senft, Anna, Bikoff, Elizabeth, Robertson, Elizabeth

Source: In Mechanisms of Development July 2017 145 Supplement:S7-S7

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Publisher Correction: The T-box transcription factor Eomesodermin governs haemogenic competence of yolk sac mesodermal progenitors

Authors: Harland, Luke T. G., Simon, Claire S., Senft, Anna D., Costello, Ita, Greder, Lucas, Imaz-Rosshandler, Ivan, Göttgens, Berthold, Marioni, John C., Bikoff, Elizabeth K., Porcher, Catherine, de Bruijn, Marella F. T. R., Robertson, Elizabeth J.

Source: Nature Cell Biology; March 2021, Vol. 23 Issue: 3 p293-293, 1p

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The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis.

Authors: Müller, Pari-Sima, Schulz, Ramona, Maretto, Silvia, Costello, Ita, Srinivas, Shankar, Bikoff, Elizabeth, Robertson, Elizabeth

Source: Development (09501991); Apr2011, Vol. 138 Issue 7, p8-8, 1p

Subject Terms: FIBRONECTINS, MYOCARDIUM, MORPHOGENESIS, EMBRYOS, HEART failure