Plasmid CpG Depletion Improves Degree and Duration of Tumor Gene Expression After Intravenous Administration of Polyplexes.

Authors: Holger de Wolf, Nina Johansson, Anh-Thy Thong, Cor Snel, Enrico Mastrobattista, Wim Hennink, Gert Storm

Source: Pharmaceutical Research; Jul2008, Vol. 25 Issue 7, p1654-1662, 9p

Subject Terms: GENES, MOBILE genetic elements, TUMORS, CYSTS (Pathology)

Effect of Liposome Characteristics and Dose on the Pharmacokinetics of Liposomes Coated with Poly(amino acid)s.

Authors: Birgit Romberg, Christien Oussoren, Cor Snel, Wim Hennink, Gert Storm

Source: Pharmaceutical Research; Dec2007, Vol. 24 Issue 12, p2394-2401, 8p

Subject Terms: CYTOPLASM, PHOSPHOLIPIDS, BILAYER lipid membranes, COATING processes

Biodegradable Poly(2-Dimethylamino Ethylamino)Phosphazene for In Vivo Gene Delivery to Tumor Cells. Effect of Polymer Molecular Weight.

Authors: Holger de Wolf, Markus de Raad, Cor Snel, Mies van Steenbergen, Marcel Fens, Gert Storm, Wim Hennink

Source: Pharmaceutical Research; Aug2007, Vol. 24 Issue 8, p1572-1580, 9p

Subject Terms: MOLECULAR weights, LINEAR algebra, DIMETHYLAMINOETHANOL, CHROMATOGRAPHIC analysis