Multi-adductomics: Advancing mass spectrometry techniques for comprehensive exposome characterization

Authors: Chao, Mu-Rong, Chang, Yuan-Jhe, Cooke, Marcus S., Hu, Chiung-Wen

Source: In Trends in Analytical Chemistry November 2024 180

DNA modifications: Biomarkers for the exposome?

Authors: Möller, Carolina, Virzi, Jazmine, Chang, Yuan-Jhe, Keidel, Alexandra, Chao, Mu-Rong, Hu, Chiung-Wen, Cooke, Marcus S.

Source: In Environmental Toxicology and Pharmacology June 2024 108

Redox modulation of oxidatively-induced DNA damage by ascorbate enhances both in vitro and ex-vivo DNA damage formation and cell death in melanoma cells

Authors: Najeeb, Hishyar A., Sanusi, Timi, Saldanha, Gerald, Brown, Karen, Cooke, Marcus S., Jones, George DD.

Source: In Free Radical Biology and Medicine March 2024 213:309-321

Genetic and epigenetic instability induced by betel quid associated chemicals

Authors: Muthukumaran, Rajendra Bose, Bhattacharjee, Pritha, Bhowmick, Priya, Zote, Lalrinawma, Kumar, Nachimuthu Senthil, Jahau, Lalrintluanga, Cooke, Marcus S., Hu, Chiung-Wen, Chao, Mu-Rong

Source: Toxicology reports. 10:223-234

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How Robust Is the Evidence for a Role of Oxidative Stress in Autism Spectrum Disorders and Intellectual Disabilities?

Authors: Burke, Shanna L. (ORCID 0000-0001-6969-3536), Cobb, Jessica, Agarwal, Rumi, Maddux, Marlaina, Cooke, Marcus S.

Source: Journal of Autism and Developmental Disorders. May 2021 51(5):1428-1445.

Peer Reviewed: Y

Page Count: 18

Descriptors: Stress Variables, Intellectual Disability, Autism, Pervasive Developmental Disorders, Pathology, Role, Correlation, Biochemistry, Research Methodology, Evidence

Perspectives on Cyclobutane Pyrimidine Dimers—Rise of the Dark Dimers†

Authors: Lawrence, Karl P., Delinasios, George J., Premi, Sanjay, Young, Antony R., Cooke, Marcus S.

Source: Photochemistry and photobiology. 98(3):609-616

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100151079138.0x000001&indx=1&recIds=ETOCvdc_100151079138.0x000001

Investigating the origins of the mutational signatures in cancer.

Authors: Boysen, Gunnar, Alexandrov, Ludmil B, Rahbari, Raheleh, Nookaew, Intawat, Ussery, Dave, Chao, Mu-Rong, Hu, Chiung-Wen, Cooke, Marcus S

Source: Nucleic Acids Research; 1/13/2025, Vol. 53 Issue 1, p1-15, 15p

Is high resolution a strict requirement for mass spectrometry-based cellular DNA adductomics?

Authors: Chang, Yuan-Jhe, Cooke, Marcus S., Chen, Yet-Ran, Yang, Shun-Fa, Li, Pei-Shan, Hu, Chiung-Wen, Chao, Mu-Rong

Source: In Chemosphere July 2021 274

Biomarkers of nucleic acid oxidation – A summary state-of-the-art

Authors: Chao, Mu-Rong, Evans, Mark D., Hu, Chiung-Wen, Ji, Yunhee, Møller, Peter, Rossner, Pavel, Cooke, Marcus S.

Source: In Redox Biology June 2021 42

Alkylating and oxidative stresses in smoking and non-smoking patients with COPD: Implications for lung carcinogenesis

Authors: Shih, Ying-Ming, Chang, Yuan-Jhe, Cooke, Marcus S., Pan, Chih-Hong, Hu, Ching-Hsuan, Chao, Mu-Rong, Hu, Chiung-Wen

Source: In Free Radical Biology and Medicine 20 February 2021 164:99-106

Towards a comprehensive view of 8-oxo-7,8-dihydro-2’-deoxyguanosine: Highlighting the intertwined roles of DNA damage and epigenetics in genomic instability

Authors: Gorini, Francesca, Scala, Giovanni, Cooke, Marcus S., Majello, Barbara, Amente, Stefano ^*

Source: In DNA Repair January 2021 97

Commentary on: Is preheat necessary for the measurement of 8‐oxo‐7, 8‐dihydroguanosine and 8‐oxo‐7, 8‐dihydro‐2′‐deoxyguanosine in urine samples

Authors: Hu, Chiung‐Wen, Cooke, Marcus S., Wang, Yi‐Jhen, Chao, Mu‐Rong

Source: Journal of clinical laboratory analysis. 37(6)

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Nucleic acid adductomics – The next generation of adductomics towards assessing environmental health risks

Authors: Cooke, Marcus S., Chang, Yuan-Jhe, Chen, Yet-Ran, Hu, Chiung-Wen, Chao, Mu-Rong

Source: Science of the total environment. 856(P2)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178905250.0x000001&indx=1&recIds=ETOCvdc_100178905250.0x000001

Mycoplasma infection of cultured cells induces oxidative stress and attenuates cellular base excision repair activity

Authors: Ji, Yunhee, Karbaschi, Mahsa, Cooke, Marcus S.

Source: In Mutation Research - Genetic Toxicology and Environmental Mutagenesis September 2019 845

Influence of skin melanisation and ultraviolet radiation on biomarkers of systemic oxidative stress

Authors: Shih, Barbara B., Farrar, Mark D., Vail, Andy, Allan, Donald, Chao, Mu-Rong, Hu, Chiung-Wen, Jones, George D.D., Cooke, Marcus S., Rhodes, Lesley E.

Source: Free radical biology and medicine. 160:40-46

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100136656433.0x000001&indx=1&recIds=ETOCvdc_100136656433.0x000001

Chilling apparatus

Clinical relevance of guanine-derived urinary biomarkers of oxidative stress, determined by LC-MS/MS

Authors: Shih, Ying-Ming, Cooke, Marcus S., Pan, Chih-Hong, Chao, Mu-Rong, Hu, Chiung-Wen

Source: In Redox Biology January 2019 20:556-565

Urinary DNA adductomics – A novel approach for exposomics

Authors: Cooke, Marcus S., Hu, Chiung-Wen, Chang, Yuan-Jhe, Chao, Mu-Rong

Source: In Environment International December 2018 121 Part 2:1033-1038

Children are particularly vulnerable to environmental tobacco smoke exposure: Evidence from biomarkers of tobacco-specific nitrosamines, and oxidative stress

Authors: Chao, Mu-Rong, Cooke, Marcus S., Kuo, Chung-Yih, Pan, Chih-Hong, Liu, Hung-Hsin, Yang, Hao-Jan, Chen, Szu-Chieh, Chiang, Yi-Chen, Hu, Chiung-Wen

Source: In Environment International November 2018 120:238-245

Fractional Sunburn Threshold UVR Doses Generate Equivalent Vitamin D and DNA Damage in Skin Types I–VI but with Epidermal DNA Damage Gradient Correlated to Skin Darkness

Authors: Shih, Barbara B., Farrar, Mark D., Cooke, Marcus S., Osman, Joanne, Langton, Abigail K., Kift, Richard, Webb, Ann R., Berry, Jacqueline L., Watson, Rachel E.B., Vail, Andy, de Gruijl, Frank R., Rhodes, Lesley E.

Source: In Journal of Investigative Dermatology October 2018 138(10):2244-2252