New views of old proteins: clarifying the enigmatic proteome

Authors: Functional, Participants in a NIH Workshop on, Proteomics, Integrative, Johnson, Kristin E. Burnum, Conrads, Thomas P., Drake, Richard R., Herr, Amy E., Iyengar, Ravi, Kelly, Ryan T., Lundberg, Emma, MacCoss, Michael J., Naba, Alexandra, Nolan, Garry P., Pevzner, Pavel A., Rodland, Karin D., Sechi, Salvatore, Slavov, Nikolai, Spraggins, Jeffrey M., Van Eyk, Jennifer E., Vidal, Marc, Vogel, Christine, Walt, David R., Kelleher, Neil L.

Subject Terms: Quantitative Biology - Biomolecules

Access URL: http://arxiv.org/abs/2108.07660

Survival disparities in non-Hispanic Black and White cervical cancer patients vary by histology and are largely explained by modifiable factors

Authors: Kucera, Calen W., Chappell, Nicole P., Tian, Chunqiao, Richardson, Michael T., Tarney, Christopher M., Hamilton, Chad A., Chan, John K., Kapp, Daniel S., Leath, Charles A., III, Casablanca, Yovanni, Rojas, Christine, Sitler, Collin A., Wenzel, Lari, Klopp, Ann, Jones, Nathaniel L., Rocconi, Rodney P., Farley, John H., O'Connor, Timothy D., Shriver, Craig D., Bateman, Nicholas W., Conrads, Thomas P., Phippen, Neil T., Maxwell, G. Larry, Darcy, Kathleen M.

Source: In Gynecologic Oncology May 2024 184:224-235

Racial, ethnic and country of origin disparities in aggressive endometrial cancer histologic subtypes

Authors: Winkler, Stuart S., Tian, Chunqiao, Casablanca, Yovanni, Bateman, Nicholas W., Jokajtys, Suzanne, Kucera, Calen W., Tarney, Christopher M., Chan, John K., Richardson, Michael T., Kapp, Daniel S., Liao, Cheng-I, Hamilton, Chad A., Leath, Charles A., III, Reddy, Megan, Cote, Michele L., O'Connor, Timothy D., Jones, Nathaniel L., Rocconi, Rodney P., Powell, Matthew A., Farley, John, Shriver, Craig D., Conrads, Thomas P., Phippen, Neil T., Maxwell, G. Larry, Darcy, Kathleen M.

Source: In Gynecologic Oncology May 2024 184:31-42

Disease progression, survival, and molecular disparities in Black and White patients with endometrioid endometrial carcinoma in real-world registries and GOG/NRG oncology randomized phase III clinical trials

Authors: Kopelman, Zachary A., Tian, Chunqiao, Tumas, Jordyn, Phippen, Neil T., Tarney, Christopher M., Hope, Erica R., Winkler, Stuart S., Jokajtys, Suzanne, Kucera, Calen W., Chan, John K., Richardson, Michael T., Kapp, Daniel S., Hamilton, Chad A., Leath, Charles A., III, Jones, Nathaniel L., Rocconi, Rodney P., Farley, John H., Secord, Angeles Alvarez, Cosgrove, Casey M., Powell, Matthew A., Klopp, Ann, Walker, Joan L., Fleming, Gini F., Bateman, Nicholas W., Conrads, Thomas P., Maxwell, G. Larry, Darcy, Kathleen M.

Source: In Gynecologic Oncology April 2024 183:103-114

ProteoMixture: A cell type deconvolution tool for bulk tissue proteomic data

Authors: Teng, Pang-ning, Schaaf, Joshua P., Abulez, Tamara, Hood, Brian L., Wilson, Katlin N., Litzi, Tracy J., Mitchell, David, Conrads, Kelly A., Hunt, Allison L., Olowu, Victoria, Oliver, Julie, Park, Fred S., Edwards, Marshé, Chiang, AiChun, Wilkerson, Matthew D., Raj-Kumar, Praveen-Kumar, Tarney, Christopher M., Darcy, Kathleen M., Phippen, Neil T., Maxwell, G. Larry, Conrads, Thomas P., Bateman, Nicholas W.

Source: In iScience 15 March 2024 27(3)

Fear of recurrence, emotional well-being and quality of life among long-term advanced ovarian cancer survivors

Authors: Osann, Kathryn, Wenzel, Lari, McKinney, Chelsea, Wagner, Lynne, Cella, David, Fulci, Giulia, Scroggins, Mary J., Lankes, Heather A., Wang, Victoria, Nephew, Kenneth P., Maxwell, George L., Mok, Samuel C., Conrads, Thomas P., Miller, Austin, Birrer, Michael

Source: Gynecologic oncology. 171:151-158

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185925097.0x000001&indx=1&recIds=ETOCvdc_100185925097.0x000001

CCNE1 and survival of patients with tubo‐ovarian high‐grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study

Authors: Kang, Eun‐Young, Weir, Ashley, Meagher, Nicola S., Farrington, Kyo, Nelson, Gregg S., Ghatage, Prafull, Lee, Cheng‐Han, Riggan, Marjorie J., Bolithon, Adelyn, Popovic, Gordana, Leung, Betty, Tang, Katrina, Lambie, Neil, Millstein, Joshua, Alsop, Jennifer, Anglesio, Michael S., Ataseven, Beyhan, Barlow, Ellen, Beckmann, Matthias W., Berger, Jessica, Bisinotto, Christiani, Bösmüller, Hans, Boros, Jessica, Brand, Alison H., Brooks‐Wilson, Angela, Brucker, Sara Y., Carney, Michael E., Casablanca, Yovanni, Cazorla‐Jiménez, Alicia, Cohen, Paul A., Conrads, Thomas P., Cook, Linda S., Coulson, Penny, Courtney‐Brooks, Madeleine, Cramer, Daniel W., Crowe, Philip, Cunningham, Julie M., Cybulski, Cezary, Darcy, Kathleen M., El‐Bahrawy, Mona A., Elishaev, Esther, Erber, Ramona, Farrell, Rhonda, Fereday, Sian, Fischer, Anna, García, María J., Gayther, Simon A., Gentry‐Maharaj, Aleksandra, Gilks, C. Blake, Grube, Marcel, Harnett, Paul R., Harrington, Shariska Petersen, Harter, Philipp, Hartmann, Arndt, Hecht, Jonathan L., Heikaus, Sebastian, Hein, Alexander, Heitz, Florian, Hendley, Joy, Hernandez, Brenda Y., Polo, Susanna Hernando, Heublein, Sabine, Hirasawa, Akira, Høgdall, Estrid, Høgdall, Claus K., Horlings, Hugo M., Huntsman, David G., Huzarski, Tomasz, Jewell, Andrea, Jimenez‐Linan, Mercedes, Jones, Michael E., Kaufmann, Scott H., Kennedy, Catherine J., Khabele, Dineo, Kommoss, Felix K. F., Kruitwagen, Roy F. P. M., Lambrechts, Diether, Le, Nhu D., Lener, Marcin, Lester, Jenny, Leung, Yee, Linder, Anna, Loverix, Liselore, Lubiński, Jan, Madan, Rashna, Maxwell, G. Larry, Modugno, Francesmary, Neuhausen, Susan L., Olawaiye, Alexander, Olbrecht, Siel, Orsulic, Sandra, Palacios, José, Pearce, Celeste Leigh, Pike, Malcolm C., Quinn, Carmel M., Mohan, Ganendra Raj, Rodríguez‐Antona, Cristina, Ruebner, Matthias, Ryan, Andy, Salfinger, Stuart G., Sasamoto, Naoko, Schildkraut, Joellen M., Schoemaker, Minouk J., Shah, Mitul, Sharma, Raghwa, Shvetsov, Yurii B., Singh, Naveena, Sonke, Gabe S., Steele, Linda, Stewart, Colin J. R., Sundfeldt, Karin, Swerdlow, Anthony J., Talhouk, Aline, Tan, Adeline, Taylor, Sarah E., Terry, Kathryn L., Tołoczko, Aleksandra, Traficante, Nadia, Vijver, Koen K., Aa, Maaike A., Gorp, Toon, Nieuwenhuysen, Els, van‐Wagensveld, Lilian, Vergote, Ignace, Vierkant, Robert A., Wang, Chen, Wilkens, Lynne R., Winham, Stacey J., Wu, Anna H., Benitez, Javier, Berchuck, Andrew, Candido dos Reis, Francisco J., DeFazio, Anna, Fasching, Peter A., Goode, Ellen L., Goodman, Marc T., Gronwald, Jacek, Karlan, Beth Y., Kommoss, Stefan, Menon, Usha, Sinn, Hans‐Peter, Staebler, Annette, Brenton, James D., Bowtell, David D., Pharoah, Paul D. P., Ramus, Susan J., Köbel, Martin

Source: Cancer. 129(5):697-713

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173055681.0x000001&indx=1&recIds=ETOCvdc_100173055681.0x000001

Metronomic dosing of ovarian cancer cells with the ATR inhibitor AZD6738 leads to loss of CDC25A expression and resistance to ATRi treatment

Authors: Ao, Wei, Kim, Hong Im, Tommarello, Domenic, Conrads, Kelly A., Hood, Brian L., Litzi, Tracy, Abulez, Tamara, Teng, Pang-Ning, Dalgard, Clifton L., Zhang, Xijun, Wilkerson, Matthew D., Darcy, Kathleen M., Tarney, Christopher M., Phippen, Neil T., Bakkenist, Christopher J., Maxwell, G. Larry, Conrads, Thomas P., Risinger, John I., Bateman, Nicholas W.

Source: In Gynecologic Oncology October 2023 177:60-71

Expression of CYP450 enzymes in human fetal membranes and its implications in xenobiotic metabolism during pregnancy

Authors: Kammala, Ananth Kumar, Lintao, Ryan C.V., Vora, Natasha, Mosebarger, Angela, Khanipov, Kamil, Golovko, George, Yaklic, Jerome L., Peltier, Morgan R., Conrads, Thomas P., Menon, Ramkumar

Source: In Life Sciences 15 October 2022 307

Conditional estimates for uterine serous cancer: Tools for survivorship counseling and planning

Authors: Nolin, Angela C., Tian, Chunqiao, Hamilton, Chad A., Casablanca, Yovanni, Bateman, Nicholas W., Chan, John K., Cote, Michele L., Shriver, Craig D., Powell, Matthew A., Phippen, Neil T., Conrads, Thomas P., Maxwell, G. Larry, Darcy, Kathleen M.

Source: Gynecologic oncology. 166(1):90-99

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100185120783.0x000001&indx=1&recIds=ETOCvdc_100185120783.0x000001

New Views of Old Proteins: Clarifying the Enigmatic Proteome

Authors: Burnum-Johnson, Kristin E., Conrads, Thomas P., Drake, Richard R., Herr, Amy E., Iyengar, Ravi, Kelly, Ryan T., Lundberg, Emma, MacCoss, Michael J., Naba, Alexandra, Nolan, Garry P., Pevzner, Pavel A., Rodland, Karin D., Sechi, Salvatore, Slavov, Nikolai, Spraggins, Jeffrey M., Van Eyk, Jennifer E., Vidal, Marc, Vogel, Christine, Walt, David R., Kelleher, Neil L.

Source: In Molecular & Cellular Proteomics July 2022 21(7)

Multiomic analysis of uterine leiomyomas in self-described Black and White women: molecular insights into health disparities

Authors: Bateman, Nicholas W., Abulez, Tamara, Tarney, Christopher M., Bariani, Maria V., Driscoll, Jordan A., Soltis, Anthony R., Zhou, Ming, Hood, Brian L., Litzi, Tracy, Conrads, Kelly A., Jackson, Amanda, Oliver, Julie, Ganakammal, Satishkumar Ranganathan, Schneider, Frank, Dalgard, Clifton L., Wilkerson, Matthew D., Smith, Barbara, Borda, Victor, O’Connor, Timothy, Segars, James, Shobeiri, S. Abbas, Phippen, Neil T., Darcy, Kathleen M., Al-Hendy, Ayman, Conrads, Thomas P., Maxwell, George Larry

Source: In American Journal of Obstetrics and Gynecology September 2024 231(3):321-321

Peptide ancestry informative markers in uterine neoplasms from women of European, African, and Asian ancestry

Authors: Bateman, Nicholas W., Tarney, Christopher M., Abulez, Tamara S., Hood, Brian L., Conrads, Kelly A., Zhou, Ming, Soltis, Anthony R., Teng, Pang-Ning, Jackson, Amanda, Tian, Chunqiao, Dalgard, Clifton L., Wilkerson, Matthew D., Kessler, Michael D., Goecker, Zachary, Loffredo, Jeremy, Shriver, Craig D., Hu, Hai, Cote, Michele, Parker, Glendon J., Segars, James, Al-Hendy, Ayman, Risinger, John I., Phippen, Neil T., Casablanca, Yovanni, Darcy, Kathleen M., Maxwell, G. Larry, Conrads, Thomas P., O'Connor, Timothy D.

Source: In iScience 21 January 2022 25(1)

Obesity and altered angiogenic-related gene expression in endometrial cancer

Authors: Cobb, Lauren Patterson, Siamakpour-Reihani, Sharareh, Zhang, Dadong, Qin, Xiaodi, Owzar, Kouros, Zhou, Chunxiao, Conrads, Thomas P., Maxwell, G. Larry, Darcy, Kathleen M., Bateman, Nicholas W., Litzi, Tracy, Bae-Jump, Victoria, Secord, Angeles Alvarez

Source: In Gynecologic Oncology November 2021 163(2):320-326

Extensive three-dimensional intratumor proteomic heterogeneity revealed by multiregion sampling in high-grade serous ovarian tumor specimens

Authors: Hunt, Allison L., Bateman, Nicholas W., Barakat, Waleed, Makohon-Moore, Sasha, Hood, Brian L., Conrads, Kelly A., Zhou, Ming, Calvert, Valerie, Pierobon, Mariaelena, Loffredo, Jeremy, Litzi, Tracy J., Oliver, Julie, Mitchell, Dave, Gist, Glenn, Rojas, Christine, Blanton, Brian, Robinson, Emma L., Odunsi, Kunle, Sood, Anil K., Casablanca, Yovanni, Darcy, Kathleen M., Shriver, Craig D., Petricoin, Emanuel F., Rao, Uma N.M., Maxwell, G. Larry, Conrads, Thomas P.

Source: In iScience 23 July 2021 24(7)

Clinical significance of homologous recombination deficiency score testing in endometrial Cancer

Authors: Siedel, Jean H., Ring, Kari L., Hu, Wei, Dood, Robert L., Wang, Ying, Baggerly, Keith, Darcy, Kathleen M., Conrads, Thomas P., Gallagher, Shannon, Tshiaba, Placede, Neff, Chris, Timms, Kirsten M., Mangala, Selanere, Westin, Shannon N., Broaddus, Russell, Lopez-Berestein, Gabriel, Lu, Karen H., Coleman, Robert L., Maxwell, George L., Sood, Anil K.

Source: In Gynecologic Oncology March 2021 160(3):777-785

Evaluation of publicly available in vitro drug sensitivity models for ovarian and uterine cancer

Authors: Kimble, Danielle C., Dvergsten, Erik, Thomeas-McEwing, Vasiliki, Karovic, Sanja, Conrads, Thomas P., Maitland, Michael L.

Source: In Gynecologic Oncology January 2021 160(1):295-301

Quality of Life and Adverse Events: Prognostic Relationships in Long-Term Ovarian Cancer Survival

Authors: Wenzel, Lari, Osann, Kathryn, McKinney, Chelsea, Cella, David, Fulci, Giulia, Scroggins, Mary J, Lankes, Heather A, Wang, Victoria, Nephew, Kenneth P, Maxwell, George L, Mok, Samuel C, Conrads, Thomas P, Miller, Austin, Mannel, Robert S, Gray, Heidi J, Hanjani, Parviz, Huh, Warner K, Spirtos, Nick, Leitao, Mario M, Glaser, Gretchen, Sharma, Sudarshan K, Santin, Alessandro D, Sperduto, Paul, Lele, Shashikant B, Burger, Robert A, Monk, Bradley J, Birrer, Michael

Source: Journal of the National Cancer Institute. 113(10):1369-1378

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131625127.0x000001&indx=1&recIds=ETOCvdc_100131625127.0x000001

Molecular Analysis of Clinically Defined Subsets of High-Grade Serous Ovarian Cancer

Authors: Lee, Sanghoon, Zhao, Li, Rojas, Christine, Bateman, Nicholas W., Yao, Hui, Lara, Olivia D., Celestino, Joseph, Morgan, Margaret B., Nguyen, Tri V., Conrads, Kelly A., Rangel, Kelly M., Dood, Robert L., Hajek, Richard A., Fawcett, Gloria L., Chu, Randy A., Wilson, Katlin, Loffredo, Jeremy L., Viollet, Coralie, Jazaeri, Amir A., Dalgard, Clifton L., Mao, Xizeng, Song, Xingzhi, Zhou, Ming, Hood, Brian L., Banskota, Nirad, Wilkerson, Matthew D., Te, Jerez, Soltis, Anthony R., Roman, Kristin, Dunn, Andrew, Cordover, David, Eterovic, Agda Karina, Liu, Jinsong, Burks, Jared K., Baggerly, Keith A., Fleming, Nicole D., Lu, Karen H., Westin, Shannon N., Coleman, Robert L., Mills, Gordon B., Casablanca, Yovanni, Zhang, Jianhua, Conrads, Thomas P., Maxwell, George L., Futreal, P. Andrew, Sood, Anil K.

Source: In Cell Reports 14 April 2020 31(2)

Racial disparities in uterine and ovarian carcinosarcoma: A population-based analysis of treatment and survival

Authors: Rojas, Christine, Tian, Chunqiao, Powell, Matthew A., Chan, John K., Bateman, Nicholas W., Conrads, Thomas P., Rocconi, Rodney P., Jones, Nathaniel L., Shriver, Craig D., Hamilton, Chad A., Maxwell, G. Larry, Casablanca, Yovanni, Darcy, Kathleen M.

Source: In Gynecologic Oncology April 2020 157(1):67-77