Sialylated IgG induces the transcription factor REST in alveolar macrophages to protect against lung inflammation and severe influenza disease

Authors: Chakraborty, Saborni ^{1, 26}, Cheng, Bowie Yik-Ling ^{1, 26}, Edwards, Desmond L. ^{1, 2, 26}, Gonzalez, Joseph C. ^{1, 3, 26}, Chiu, David Kung-Chun ⁴, Zheng, Hong ¹, Scallan, Courtney ¹, Guo, Xinrong ¹, Tan, Gene S. ^{5, 6}, Coffey, Greg P. ⁷, Conley, Pamela B. ⁷, Hume, Patrick S. ^{8, 9}, Janssen, William J. ^{8, 9}, Byers, Derek E. ¹⁰, Mudd, Philip A. ^{11, 12}, Taubenberger, Jeffery ¹³, Memoli, Matthew ¹⁴, Davis, Mark M. ^{1, 2, 3, 15}, Chua, Katrin F. ^{16, 17}, Diamond, Michael S. ^{18, 19, 20, 21, 22}, Andreakos, Evangelos ²³, Khatri, Purvesh ^{1, 3, 24}, Wang, Taia T. ^{1, 2, 3, 25, 27, ∗}

Source: In Immunity 14 January 2025 58(1):182-196

Andexanet versus prothrombin complex concentrates: Differences in reversal of factor Xa inhibitors in in vitro thrombin generation

Authors: Lu, Genmin ^*, Lin, Joyce, Bui, Khanh, Curnutte, John T., Conley, Pamela B.

Source: In Research and Practice in Thrombosis and Haemostasis November 2020 4(8):1282-1294

A phase 2 PK/PD study of andexanet alfa for reversal of rivaroxaban and edoxaban anticoagulation in healthy volunteers

Authors: Lu, Genmin, Conley, Pamela B., Leeds, Janet M., Karbarz, Mark J., Levy, Gallia G., Mathur, Vandana S., Castillo, Janice, Crowther, Mark, Curnutte, John T.

Source: In Blood Advances 25 February 2020 4(4):728-739

Transient or extended reversal of apixaban anticoagulation by andexanet alfa is equally effective in a porcine polytrauma model

Authors: Grottke, Oliver, Braunschweig, Till, Rossaint, Rolf, Akman, Necib, Leeds, Janet M., Conley, Pamela B., Honickel, Markus

Source: In British Journal of Anaesthesia August 2019 123(2):186-195

Comparison of reversal activity and mechanism of action of UHRA, andexanet, and PER977 on heparin and oral FXa inhibitors

Authors: Kalathottukaren, Manu T., Creagh, A. Louise, Abbina, Srinivas, Lu, Genmin, Karbarz, Mark J., Pandey, Anjali, Conley, Pamela B., Kizhakkedathu, Jayachandran N., Haynes, Charles

Source: In Blood Advances 28 August 2018 2(16):2104-2114

Molecular Bases of Defective Signal Transduction in the Platelet P2Y 12 Receptor of a Patient with Congenital Bleeding

Authors: Cattaneo, Marco, Zighetti, Maddalena L., Lombardi, Rossana, Martinez, Constantino, Lecchi, Anna, Conley, Pamela B., Ware, Jerry, Ruggeri, Zaverio M.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 Feb . 100(4), 1978-1983.

Access URL: https://www.jstor.org/stable/3138470

Safety, pharmacokinetics, and reversal of apixaban anticoagulation with andexanet alfa

Authors: Siegal, Deborah, Lu, Genmin, Leeds, Janet M., Karbarz, Mark, Castillo, Janice, Mathur, Vandana, Hutchaleelaha, Athiwat, Sinha, Uma, Kitt, Michael, McClure, Matt, Hollenbach, Stanley J., Curnutte, John T., Conley, Pamela B., Crowther, Mark ^*

Source: In Blood Advances 26 September 2017 1(21):1827-1838

A Clopidogrel-Insensitive Inducible Pool of P2Y12 Receptors Contributes to Thrombus Formation: Inhibition by Elinogrel, a Direct-Acting, Reversible P2Y12 Antagonist

Authors: Haberstock-Debic, Helena, Andre, Patrick, Mills, Scott, Phillips, David R., Conley, Pamela B. ^*

Source: In The Journal of Pharmacology and Experimental Therapeutics October 2011 339(1):54-61

Thienopyridines, but Not Elinogrel, Result in Off-Target Effects at the Vessel Wall That Contribute to Bleeding

Authors: André, Patrick, DeGuzman, Francis, Haberstock-Debic, Helena, Mills, Scott, Pak, Yvonne, Inagaki, Mayuko, Pandey, Anjali, Hollenbach, Stanley, Phillips, David R., Conley, Pamela B. ^*

Source: In The Journal of Pharmacology and Experimental Therapeutics July 2011 338(1):22-30

Antidotes for factor Xa inhibitors and methods of using the same

Combination therapy with a compound acting as a platelet ADP receptor inhibitor

Characterization of a Cofactor That Regulates Dimerization of a Mammalian Homeodomain Protein

Authors: Mendel, Dirk B., Khavari, Paul A., Conley, Pamela B., Graves, Mary K., Hansen, Linda P., Admon, Arie, Crabtree, Gerald R.

Source: Science, 1991 Dec . 254(5039), 1762-1767.

Access URL: https://www.jstor.org/stable/2880077

Cyanobacterial Light-Harvesting Complex Subunits Encoded in Two Red Light-Induced Transcripts

Authors: Conley, Pamela B., Lemaux, Peggy G., Grossman, Arthur R.

Source: Science, 1985 Nov 01. 230(4725), 550-553.

Access URL: https://www.jstor.org/stable/1695255

Genes Encoding Major Light-Harvesting Polypeptides are Clustered on the Genome of the Cyanobacterium Fremyella diplosiphon

Authors: Conley, Pamela B., Lemaux, Peggy G., Lomax, Terri L., Grossman, Arthur R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1986 Jun 01. 83(11), 3924-3928.

Access URL: https://www.jstor.org/stable/27800

Molecular Cloning, Functional Expression, and Chromosomal Localization of Mouse Hepatocyte Nuclear Factor 1

Authors: Kuo, Calvin J., Conley, Pamela B., Hsieh, Chih-Lin, Francke, Uta, Crabtree, Gerald R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 1990 Dec 01. 87(24), 9838-9842.

Access URL: https://www.jstor.org/stable/2356509

Antidotes for factor Xa inhibitors and methods of using the same

INTRAVENOUS AND ORAL DOSING OF A DIRECT-ACTING AND REVERSIBLE P2Y12 INHIBITOR

COMBINATION THERAPY WITH A COMPOUND ACTING AS A PLATELET ADP RECEPTOR INHIBITOR

ANTIDOTES FOR FACTOR XA INHIBITORS AND METHODS OF USING THE SAME

POTASSIUM CHANNEL MODULATORS AND PLATELET PROCOAGULANT ACTIVITY