Inflammation-driven NF-κB signaling represses ferroportin transcription in macrophages via HDAC1 and HDAC3

Authors: Marques, Oriana ^{1, 2}, Horvat, Natalie K. ^{1, 3}, Zechner, Laura ¹, Colucci, Silvia ^{1, 2}, Sparla, Richard ^{1, 2}, Zimmermann, Stefan ⁴, Neufeldt, Christopher J. ^{5, 6}, Altamura, Sandro ^{1, 2}, Qiu, Ruiyue ¹, Müdder, Katja ^{1, 2}, Weiss, Günter ^{7, 8}, Hentze, Matthias W. ^{2, 9, ∗∗}, Muckenthaler, Martina U. ^{1, 2, 3, 10, 11, ∗}

Source: In Blood 20 February 2025 145(8):866-880

FKBP12 inhibits hepcidin expression by modulating BMP receptors interaction and ligand responsiveness in hepatocytes

Authors: Pettinato, Mariateresa, Dulja, Alessandro, Colucci, Silvia, Furiosi, Valeria, Fette, Franca, Steinbicker, Andrea U., Muckenthaler, Martina U., Nai, Antonella, Pagani, Alessia, Silvestri, Laura

Source: American journal of hematology. 98(8):1223-1235

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100187344954.0x000001&indx=1&recIds=ETOCvdc_100187344954.0x000001

Constitutional PIGA mutations cause a novel subtype of hemochromatosis in patients with neurologic dysfunction

Authors: Muckenthaler, Lena, Marques, Oriana, Colucci, Silvia, Kunz, Joachim, Fabrowski, Piotr, Bast, Thomas, Altamura, Sandro, Höchsmann, Britta, Schrezenmeier, Hubert, Langlotz, Monika, Richter-Pechanska, Paulina, Rausch, Tobias, Hofmeister-Mielke, Nicole, Gunkel, Nikolas, Hentze, Matthias W., Kulozik, Andreas E., Muckenthaler, Martina U.

Source: Blood. 139(9):1418-1422

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183245067.0x000001&indx=1&recIds=ETOCvdc_100183245067.0x000001

Irisin and Metastatic Melanoma: Selective Anti-Invasiveness Activity in BRAF Wild-Type Cells.

Authors: Serratì, Simona, Zerlotin, Roberta, Manganelli, Michele, Di Fonte, Roberta, Dicarlo, Manuela, Oranger, Angela, Colaianni, Graziana, Porcelli, Letizia, Azzariti, Amalia, Guida, Stefania, Grano, Maria, Colucci, Silvia Concetta, Guida, Gabriella

Source: International Journal of Molecular Sciences; Jan2025, Vol. 26 Issue 2, p652, 13p

Subject Terms: IRISIN, ENERGY metabolism, CELL proliferation, GENE expression, GELATIN

Reference Intervals (RIs) of the Bone Turnover Markers (BTMs) in Children and Adolescents: A Proposal for Effective Use.

Authors: Brescia, Vincenzo, Lovero, Roberto, Fontana, Antonietta, Zerlotin, Roberta, Colucci, Silvia Concetta, Grano, Maria, Cazzolla, Angela Pia, Di Serio, Francesca, Crincoli, Vito, Faienza, Maria Felicia

Source: Biomedicines; Jan2025, Vol. 13 Issue 1, p34, 24p

Subject Terms: BONE growth, BONE remodeling, ACID phosphatase, AGE groups, BONE metabolism

20 years of Hepcidin: How far we have come

Authors: Colucci, Silvia, Marques, Oriana, Altamura, Sandro

Source: In Seminars in Hematology July 2021 58(3):132-144

Liver Sinusoidal Endothelial Cells Suppress Bone Morphogenetic Protein 2 Production in Response to TGFβ Pathway Activation

Authors: Colucci, Silvia, Altamura, Sandro, Marques, Oriana, Dropmann, Anne, Horvat, Natalie K., Müdder, Katja, Hammad, Seddik, Dooley, Steven, Muckenthaler, Martina U.

Source: Hepatology. 74(4):2186-2200

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131459156.0x000001&indx=1&recIds=ETOCvdc_100131459156.0x000001

Rationale and Protocol of the ETERNITY-ITA Study: Use of Etelcalcetide for Preserving Vitamin K-Dependent Protein Activity—An Italian Study.

Authors: Fusaro, Maria, Aghi, Andrea, Marino, Carmela, Mallamaci, Francesca, Plebani, Mario, Zaninotto, Martina, Grano, Maria, Colucci, Silvia, Gallieni, Maurizio, Nickolas, Thomas L., Giannini, Sandro, Sella, Stefania, Simioni, Paolo, Bazzocchi, Alberto, Guglielmi, Giuseppe, Taddei, Fulvia, Schileo, Enrico, Versace, Maria Carmela, Tripepi, Giovanni

Source: Journal of Clinical Medicine; Oct2024, Vol. 13 Issue 19, p5888, 11p

Subject Terms: RENAL osteodystrophy, MATRIX Gla protein, VITAMIN K, BONE health, ARTERIAL calcification

Regulation of iron homeostasis: Lessons from mouse models

Authors: Altamura, Sandro, Marques, Oriana, Colucci, Silvia, Mertens, Christina, Alikhanyan, Kristina, Muckenthaler, Martina U.

Source: In Molecular Aspects of Medicine October 2020 75

Impact of 10‐day bed rest on serum levels of irisin and markers of musculoskeletal metabolism

Authors: Oranger, Angela, Storlino, Giuseppina, Dicarlo, Manuela, Zerlotin, Roberta, Pignataro, Patrizia, Sanesi, Lorenzo, Narici, Marco, Pišot, Rado, Simunič, Bostjan, Colaianni, Graziana, Grano, Maria, Colucci, Silvia

Source: FASEB journal. 37(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173368408.0x000001&indx=1&recIds=ETOCvdc_100173368408.0x000001

Irisin prevents microgravity‐induced impairment of osteoblast differentiation in vitro during the space flight CRS‐14 mission

Authors: Colucci, Silvia, Colaianni, Graziana, Brunetti, Giacomina, Ferranti, Francesca, Mascetti, Gabriele, Mori, Giorgio, Grano, Maria

Source: FASEB journal. 34(8):10096-10106

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100122653754.0x000001&indx=1&recIds=ETOCvdc_100122653754.0x000001

LIGHT/TNFSF14 regulates estrogen deficiency‐induced bone loss

Authors: Brunetti, Giacomina, Storlino, Giuseppina, Oranger, Angela, Colaianni, Graziana, Faienza, Maria F, Ingravallo, Giuseppe, Di Comite, Mariasevera, Reseland, Janne E, Celi, Monica, Tarantino, Umberto, Passeri, Giovanni, Ware, Carl F, Grano, Maria, Colucci, Silvia

Source: Journal of pathology. 250(4):440-451

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100111911184.0x000001&indx=1&recIds=ETOCvdc_100111911184.0x000001

LIGHT/TNFSF14 Promotes Osteolytic Bone Metastases in Non‐small Cell Lung Cancer Patients

Authors: Brunetti, Giacomina, Belisario, Dimas C, Bortolotti, Sara, Storlino, Giuseppina, Colaianni, Graziana, Faienza, Maria F, Sanesi, Lorenzo, Alliod, Valentina, Buffoni, Lucio, Centini, Elisa, Voena, Claudia, Pulito, Roberta, Novello, Silvia, Ingravallo, Giuseppe, Rizzi, Rita, Mori, Giorgio, Reseland, Janne E, Ware, Carl F, Colucci, Silvia, Ferracini, Riccardo, Grano, Maria, Roato, Ilaria

Source: Journal of bone and mineral research. 35(4):671-680

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107710697.0x000001&indx=1&recIds=ETOCvdc_100107710697.0x000001

Irisin Prevents Disuse‐Induced Osteocyte Apoptosis

Authors: Storlino, Giuseppina, Colaianni, Graziana, Sanesi, Lorenzo, Lippo, Luciana, Brunetti, Giacomina, Errede, Mariella, Colucci, Silvia, Passeri, Giovanni, Grano, Maria

Source: Journal of bone and mineral research. 35(4):766-775

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100106892434.0x000001&indx=1&recIds=ETOCvdc_100106892434.0x000001

Total reflection X-ray fluorescence spectrometry for trace determination of iron and some additional elements in biological samples

Authors: Gruber, Andreas, Müller, Riccarda, Wagner, Alessa, Colucci, Silvia, Spasić, Maja Vujić, Leopold, Kerstin

Source: Analytical and bioanalytical chemistry. 412(24):6419-6429

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100167701263.0x000001&indx=1&recIds=ETOCvdc_100167701263.0x000001

Irisin prevents trabecular bone damage and tumor invasion in a mouse model of multiple myeloma.

Authors: Zerlotin, Roberta, Oranger, Angela, Pignataro, Patrizia, Dicarlo, Manuela, Sanesi, Lorenzo, Suriano, Clelia, Storlino, Giuseppina, Rizzi, Rita, Mestice, Anna, Gioia, Sante Di, Mori, Giorgio, Grano, Maria, Colaianni, Graziana, Colucci, Silvia

Source: JBMR Plus; Jul2024, Vol. 8 Issue 7, p1-14, 14p

Subject Terms: CANCELLOUS bone, COMPACT bone, IRISIN, FRACTURE healing, SPONTANEOUS fractures

Irisin Levels in Cerebrospinal Fluid Correlate with Biomarkers and Clinical Dementia Scores in Alzheimer Disease.

Authors: Dicarlo, Manuela, Pignataro, Patrizia, Zecca, Chiara, Dell'Abate, Maria Teresa, Urso, Daniele, Gnoni, Valentina, Giugno, Alessia, Borlizzi, Francesco, Zerlotin, Roberta, Oranger, Angela, Colaianni, Graziana, Colucci, Silvia, Logroscino, Giancarlo, Grano, Maria

Source: Annals of Neurology; Jul2024, Vol. 96 Issue 1, p61-73, 13p

Subject Terms: IRISIN, CEREBROSPINAL fluid, ALZHEIMER'S disease, TAU proteins, DEMENTIA, MILD cognitive impairment

High irisin levels are associated with better glycemic control and bone health in children with Type 1 diabetes

Authors: Faienza, Maria Felicia, Brunetti, Giacomina, Sanesi, Lorenzo, Colaianni, Graziana, Celi, Monica, Piacente, Laura, D'Amato, Gabriele, Schipani, Ernestina, Colucci, Silvia, Grano, Maria

Source: In Diabetes Research and Clinical Practice July 2018 141:10-17

Mechanisms of Enhanced Osteoclastogenesis in Alkaptonuria

Authors: Brunetti, Giacomina, Tummolo, Albina, D'Amato, Gabriele, Gaeta, Alberto, Ortolani, Federica, Piacente, Laura, Giordano, Paola, Colucci, Silvia, Grano, Maria, Papadia, Francesco, Faienza, Maria F.

Source: In The American Journal of Pathology April 2018 188(4):1059-1068

Transferrin receptor 2 controls bone mass and pathological bone formation via BMP and Wnt signalling

Authors: Rauner, Martina, Baschant, Ulrike, Roetto, Antonella, Pellegrino, Rosa Maria, Rother, Sandra, Salbach-Hirsch, Juliane, Weidner, Heike, Hintze, Vera, Campbell, Graeme, Petzold, Andreas, Lemaitre, Regis, Henry, Ian, Bellido, Teresita, Theurl, Igor, Altamura, Sandro, Colucci, Silvia, Muckenthaler, Martina U., Schett, Georg, Komla-Ebri, Davide S. K., Bassett, J. H. Duncan, Williams, Graham R., Platzbecker, Uwe, Hofbauer, Lorenz C.

Source: Nature metabolism. 1(1):111-124

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125165216.0x000001&indx=1&recIds=ETOCvdc_100125165216.0x000001