Oral colon-targeted responsive chitosan/pectin-based nanoparticles propels the application of tofacitinib in colitis therapy

Authors: Chunfei Wu, Chuanlin Bi, Geun-soo Kim, Zizhen Yang, Shuao Li, Tong Dai, Xiaoyu Wu, Jiaojiao Tan, Ningning He, Shangyong Li

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-11 (2025)

Subject Terms: Ulcerative colitis, Colon-targeted drug delivery, pH-sensitive release, Enzymatic-triggered release, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/0f265c9c5de74404a7b4815b85f33d59

Oral colon-targeted pH-responsive polymeric nanoparticles loading naringin for enhanced ulcerative colitis therapy

Authors: Shilong Fan, Yue Zhao, Yinlian Yao, Xin Shen, Xingxing Chai, Jiahui Li, Jiang Pi, Xueqin Huang, Hua Jin, Zhikun Zhou

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)

Subject Terms: Oral delivery, Colon-targeted nanoparticles, Naringin, Ulcerative colitis, Pro-inflammatory cytokines, Reactive oxygen species, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/d21b9c450c334dd493d886c90ff54eb5

Oral colon-targeted delivery of recombinant human MANF for alleviation of ulcerative colitis

Authors: Jie Zhou, Tian-Le Li, Bo Wei, Yue-Feng Ruan, Ye-Qin Wang, Jiao-Yan Liu, Meng-Meng Song, Yu-Xian Shen

Source: International Journal of Pharmaceutics: X, Vol 9, Iss , Pp 100320- (2025)

Subject Terms: MANF, Oral delivery, Colon targeted, Hydrogel, Ulcerative colitis, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2590156725000052; https://doaj.org/toc/2590-1567

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Nanotechnology-based drug delivery system for targeted therapy of ulcerative colitis from traditional Chinese medicine: A review

Authors: Gao, Chengcheng, Yang, Zerun, Song, Ruirui, Sheng, Huagang ^⁎, Zhu, Liqiao ^⁎

Source: In International Journal of Pharmaceutics 30 March 2025 673

Structural, physicochemical, and in vitro digestion properties of microgel-reinforced synbiotic hydrogel beads filled with pectic oligosaccharides as a delivery system for Limosilactobacillus reuteri

Authors: Yi, Hee Jin, Kang, Yu-Ra, Chang, Yoon Hyuk ^⁎

Source: In Food Chemistry 1 February 2025 464 Part 2

Enteric coating of halloysite nanotube/ o-butyrylated chitosan microspheres for the co-delivery of paeoniflorin and butyric acid to colon

Authors: Li, Haigang ^a, Liu, Jiaxuan ^a, Zhang, Lei ^b, Zhu, Xinru ^a, Jiang, Jing ^a, Ge, Zhaohui ^a, Zuo, Yifei ^a, Chen, Xiangzhu ^a, Zhang, Chun ^{a, ⁎}

Source: In Journal of Drug Delivery Science and Technology February 2025 104

Isolation and effect of physical modification on the release characteristics Euryale ferox Salisb polysaccharide

Authors: Mal, Tuhin ^{⁎, 1}, Pandey, Anima ^⁎

Source: In International Journal of Biological Macromolecules May 2025 305 Part 2

Prebiotics empower probiotics with gastrointestinal stress resistance for colon-targeted release to synergistically alleviate colitis

Authors: Ji, Haihua, Yan, Xiaochen, Zhang, Li, Yang, Lin, Xie, Pengcheng, Gu, Fengying, Bian, Shuigen, Wan, Hao ^⁎, Nie, Shaoping ^⁎

Source: In Journal of Controlled Release 10 April 2025 380:297-316

Sodium alginate/low methoxyl pectin composite hydrogel beads prepared via gas-shearing technology for enhancing the colon-targeted delivery of probiotics and modulating gut microbiota

Authors: Zhang, Fan ^a, Zheng, Xujiao ^a, Ma, Ying ^a, Nan, Wuqiang ^a, Wu, Wenjing ^a, Chu, Ziru ^a, Sun, Xin ^c, Huang, Jihong ^d, Muratkhan, Marat ^e, Yue, Fangfang ^{a, ⁎}, Wang, Xin ^{a, b, ⁎}, Lü, Xin ^{a, ⁎}

Source: In International Journal of Biological Macromolecules April 2025 300

Modulation of mesalamine release from enteric-coated matrix tablets using natural polysaccharides for localized colonic delivery

Authors: Shilpa Sahu, Prasanta Kumar Choudhury, Gourishyam Pasa, Padala Narasimha Murthy, Poonam Sahu, Renuka Verma

Source: Journal of Applied Pharmaceutical Research, Vol 12, Iss 2, Pp 93-108 (2024)

Subject Terms: colon-targeted, matrix tablets, mesalamine (5-asa), inflammatory bowel diseases (ibd), ph-sensitive polymers, enteric coating, Pharmacy and materia medica, RS1-441, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://japtronline.com/index.php/joapr/article/view/530; https://doaj.org/toc/2348-0335

Access URL: https://doaj.org/article/03241e9281af4768a809723d0bd33dc7

pH-Dependent Drug Delivery Systems for Ulcerative Colitis Treatment

Authors: Yana Gvozdeva, Radiana Staynova

Source: Pharmaceutics, Vol 17, Iss 2, p 226 (2025)

Subject Terms: ulcerative colitis, pH-dependent drug delivery systems, pH-responsive polymers, pH-sensitive carrier, colon-targeted drug delivery, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/17/2/226; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/ab798878e5c349eea77e8ab9ba4f71e1

Design strategies, advances and future perspectives of colon-targeted delivery systems for the treatment of inflammatory bowel disease

Authors: Baoxin Zheng, Liping Wang, Yan Yi, Jun Yin, Aihua Liang

Source: Asian Journal of Pharmaceutical Sciences, Vol 19, Iss 4, Pp 100943- (2024)

Subject Terms: Colon-targeted drug delivery system, Inflammatory bowel disease, Design strategy, Treatment mechanism, Advanced complementary therapy, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1818087624000606; https://doaj.org/toc/1818-0876

Access URL: https://doaj.org/article/0f5feeb60ca8486ead6befa37a29342a

Dexamethasone-Loaded Lipid Calcium Phosphate Nanoparticles Treat Experimental Colitis by Regulating Macrophage Polarization in Inflammatory Sites

Authors: Dong K, Zhang Y, Ji HR, Guan ZL, Wang DY, Guo ZY, Deng SJ, He BY, Xing JF, You CY

Source: International Journal of Nanomedicine, Vol Volume 19, Pp 993-1016 (2024)

Subject Terms: ulcerative colitis, calcium phosphate, macrophage polarization, colon targeted delivery system, dexamethasone, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.dovepress.com/dexamethasone-loaded-lipid-calcium-phosphate-nanoparticles-treat-exper-peer-reviewed-fulltext-article-IJN; https://doaj.org/toc/1178-2013

Access URL: https://doaj.org/article/1db5b086c5284f559fdd69ef8d09b916

Colon-Targeted Poly(ADP-ribose) Polymerase Inhibitors Synergize Therapeutic Effects of Mesalazine Against Rat Colitis Induced by 2,4-Dinitrobenzenesulfonic Acid

Authors: Changyu Kang, Jaejeong Kim, Yeonhee Jeong, Jin-Wook Yoo, Yunjin Jung

Source: Pharmaceutics, Vol 16, Iss 12, p 1546 (2024)

Subject Terms: poly(ADP-ribose) polymerase inhibitor, colon-targeted drug delivery, colitis, mesalazine, prodrug, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/16/12/1546; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/638a744a30a44384a501823f094c3a06

Hyaluronic acid-functionalized DDAB/PLGA nanoparticles for improved oral delivery of magnolol in the treatment of ulcerative colitis

Authors: Li, Wei ^{a, 1}, Lin, Jie ^{b, c, 1}, Zhou, Jie ^d, He, Siqi ^d, Wang, Anqi ^a, Hu, Yingfan ^a, Li, Hanmei ^e, Zou, Liang ^{e, ⁎}, Liu, Ya ^{b, ⁎}

Source: In International Journal of Pharmaceutics 25 March 2024 653

Electrospray alginate microgels co-encapsulating degraded Konjac glucomannan and quercetin modulate human gut microbiota in vitro

Authors: Liu, Siyao, Loo, Yit Tao, Zhang, Yianna, Ng, Ken ^⁎

Source: In Food Chemistry 15 February 2024 434

Research Advances in the Multiscale Protein-polysaccharide Based Systems for Probiotics Delivery

Authors: Shuaipeng YU, Yue CUI, Lin WANG, Da LI, Xiaolu PU

Source: Shipin gongye ke-ji, Vol 44, Iss 17, Pp 470-482 (2023)

Subject Terms: protein-polysaccharide based, multiscale structure, delivery system, colon-targeted delivery, probiotics viability, Food processing and manufacture, TP368-456

File Description: electronic resource

Relation: https://doaj.org/toc/1002-0306

Access URL: https://doaj.org/article/63f3eb59571b4c7bb62dcfd1ae6aeb80

Surface-anchored microbial enzyme-responsive solid lipid nanoparticles enabling colonic budesonide release for ulcerative colitis treatment

Authors: Yipeng Zhang, Liying Wang, Zi-Dan Wang, Quan Zhou, Xuefei Zhou, Tianhua Zhou, Yi-Xin Guan, Xiangrui Liu

Source: Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-15 (2023)

Subject Terms: Solid lipid nanoparticles, Ulcerative colitis, Microbial enzyme, Colon-targeted oral drug delivery system, Sodium cellulose sulfate, Budesonide, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/6875cd13264e473c8c5395433e8e5006

Production and Characterization of Colon Targeted pH Sensitive Macrospheres and Investıgation of Release Kinetics

Authors: Hüseyin Çiçek, Cankız Gizem Delibalta, Ezgi Eren Belgin

Source: Sakarya Üniversitesi Fen Bilimleri Enstitüsü Dergisi, Vol 27, Iss 2, Pp 408-418 (2023)

Subject Terms: colon targeted drug delivery, macrosphere, controlled release, release kinetics, ph sensitive, Engineering (General). Civil engineering (General), TA1-2040, Chemistry, QD1-999

File Description: electronic resource

Relation: https://dergipark.org.tr/tr/download/article-file/2514203; https://doaj.org/toc/2147-835X

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Fabrication of pH-dependent solid dispersion for oral colon-targeted delivery of notoginsenoside R1 and its protective effects on ulcerative colitis mice

Authors: Tie, Hongyun ^{a, b, 1}, Wang, Yaru ^{a, 1}, Shang, Yunxia ^a, Li, Manlin ^{a, ∗}, Wei, Xiaohui ^{a, ∗∗}, Wang, Zhengtao ^a

Source: In Heliyon September 2023 9(9)