The BET inhibitor JQ1 targets fat metabolism and counteracts obesity

Authors: Fornelli, Claudia ^a, Sofia Cento, Alessia ^a, Nevi, Lorenzo ^b, Mastrocola, Raffaella ^a, Ferreira Alves, Gustavo ^c, Caretti, Giuseppina ^b, Collino, Massimo ^c, Penna, Fabio ^{a, ⁎}

Source: In Journal of Advanced Research February 2025 68:403-413

Cardiovascular effects of Roflumilast during sepsis: Risks or benefits?

Authors: Ferreira Alves, Gustavo, Oliveira, Junior Garcia, Nakashima, Marcelo Almeida, Delfrate, Gabrielle, Sordi, Regina, Assreuy, Jamil, da Silva-Santos, José Eduardo, Collino, Massimo, Fernandes, Daniel

Source: In European Journal of Pharmacology 15 November 2024 983

Pharmacological inhibition of CK2 by silmitasertib mitigates sepsis-induced circulatory collapse, thus improving septic outcomes in mice

Authors: Ferreira Alves, Gustavo, Aimaretti, Eleonora, da Silveira Hahmeyer, Maria Luísa, Einaudi, Giacomo, Porchietto, Elisa, Rubeo, Chiara, Marzani, Enrica, Aragno, Manuela, da Silva-Santos, José Eduardo, Cifani, Carlo, Fernandes, Daniel, Collino, Massimo

Source: In Biomedicine & Pharmacotherapy September 2024 178

Effects of anti-inflammatory [1, 2, 4]triazolo[4, 3-a] [1, 8]naphthyridine derivatives on human stimulated PMN and endothelial cells: an in vitro study

Authors: Roma Giorgio, Di Braccio Mario, Gallicchio Margherita, Collino Massimo, Dianzani Chiara, Fantozzi Roberto

Source: Journal of Inflammation, Vol 3, Iss 1, p 4 (2006)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.journal-inflammation.com/content/3/1/4; https://doaj.org/toc/1476-9255

Access URL: https://doaj.org/article/7ae77a11f72844749bad3a31468d5e49

Inhibition of the JAK/STAT Pathway With Baricitinib Reduces the Multiple Organ Dysfunction Caused by Hemorrhagic Shock in Rats

Authors: Patel, Nikita M., Collotta, Debora, Aimaretti, Eleonora, Ferreira Alves, Gustavo, Kröller, Sarah, Coldewey, Sina M., Collino, Massimo, Thiemermann, Christoph

Source: Annals of surgery. 278(1):e137-e146

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191472624.0x000001&indx=1&recIds=ETOCvdc_100191472624.0x000001

Inhibition of Bruton's Tyrosine Kinase Activity Attenuates Hemorrhagic Shock-Induced Multiple Organ Dysfunction in Rats

Authors: Patel, Nikita M., Oliveira, Filipe R. M. B., Ramos, Hanna Pillmann, Aimaretti, Eleonora, Alves, Gustavo Ferreira, Coldewey, Sina M., Collino, Massimo, Sordi, Regina, Thiemermann, Christoph

Source: Annals of surgery. 277(3):e624-e633

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188941871.0x000001&indx=1&recIds=ETOCvdc_100188941871.0x000001

RETRACTED: A Synthetic Peptide Designed to Neutralize Lipopolysaccharides Attenuates Metaflammation and Diet-Induced Metabolic Derangements in Mice.

Authors: Mohammad, Shireen, Al Zoubi, Sura, Collotta, Debora, Krieg, Nadine, Wissuwa, Bianka, Ferreira Alves, Gustavo, Purvis, Gareth S. D., Norata, Giuseppe Danilo, Baragetti, Andrea, Catapano, Alberico Luigi, Solito, Egle, Zechendorf, Elisabeth, Schürholz, Tobias, Correa-Vargas, Wilmar, Brandenburg, Klaus, Coldewey, Sina M., Collino, Massimo, Yaqoob, Muhammad M., Martin, Lukas, Thiemermann, Christoph

Source: Frontiers in Immunology; 2025, p1-18, 18p

Subject Terms: ANTIMICROBIAL peptides, EXTRACELLULAR signal-regulated kinases, PYRIN (Protein), SCAVENGER receptors (Biochemistry), PEPTIDES

RETRACTED: X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure.

Authors: O'Riordan, Caroline E., Purvis, Gareth S. D., Collotta, Debora, Krieg, Nadine, Wissuwa, Bianka, Sheikh, Madeeha H., Ferreira Alves, Gustavo, Mohammad, Shireen, Callender, Lauren A., Coldewey, Sina M., Collino, Massimo, Greaves, David R., Thiemermann, Christoph

Source: Frontiers in Immunology; 2025, p1-20, 20p

Subject Terms: BRUTON tyrosine kinase, MULTIPLE organ failure, CYTOKINE release syndrome, BACTERIAL diseases, NLRP3 protein

RETRACTED: Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice.

Authors: O'Riordan, Caroline E., Purvis, Gareth S. D., Collotta, Debora, Chiazza, Fausto, Wissuwa, Bianka, Al Zoubi, Sura, Stiehler, Lara, Martin, Lukas, Coldewey, Sina M., Collino, Massimo, Thiemermann, Christoph

Source: Frontiers in Immunology; 2025, p1-12, 12p

Subject Terms: BRUTON tyrosine kinase, WESTERN immunoblotting, NLRP3 protein, HEART diseases, BLOOD serum analysis

Advanced glycation end products and their related signaling cascades in adult survivors of childhood Hodgkin lymphoma: A possible role in the onset of late complications

Authors: Felicetti, Francesco, Aimaretti, Eleonora, Dal Bello, Federica, Gatti, Filippo, Godono, Alessandro, Saba, Francesca, Einaudi, Giacomo, Collino, Massimo, Fagioli, Franca, Aragno, Manuela, Brignardello, Enrico

Source: Free radical biology and medicine. 178:76-82

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100179597938.0x000001&indx=1&recIds=ETOCvdc_100179597938.0x000001

The Placebo Effect on Symptoms, Quality of Life, and Functional Outcomes in Patients With Angina Pectoris: A Meta-analysis of Randomized Placebo-Controlled Trials

Authors: Gallone, Guglielmo, Baldetti, Luca, Angelini, Filippo, Saglietto, Andrea, Bellettini, Matteo, Beneduce, Alessandro, Ranotti, Viola, Chiarito, Mauro, Leone, Pier Pasquale, Pagnesi, Matteo, De Filippo, Ovidio, Landra, Federico, Bruno, Francesco, Marengo, Giorgio, Collino, Massimo, Ferrante, Giuseppe, Stefanini, Giulio G., Colombo, Antonio, Al-Lamee, Rasha, Francis, Darrel P., Jolicoeur, Marc E., Henry, Timothy D., Giannini, Francesco, D'Ascenzo, Fabrizio, De Ferrari, Gaetano Maria

Source: Canadian journal of cardiology. 38(1):113-122

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100163342138.0x000001&indx=1&recIds=ETOCvdc_100163342138.0x000001

Altered hepatic sphingolipid metabolism in insulin resistant mice: Role of advanced glycation endproducts

Authors: Mastrocola, Raffaella, Dal Bello, Federica, Cento, Alessia S., Gaens, Katrien, Collotta, Debora, Aragno, Manuela, Medana, Claudio, Collino, Massimo, Wouters, Kristiaan, Schalkwijk, Casper G.

Source: In Free Radical Biology and Medicine June 2021 169:425-435

Resolvin D1 Attenuates the Organ Injury Associated With Experimental Hemorrhagic Shock

Authors: Sordi, Regina, Chiazza, Fausto, Collotta, Debora, Migliaretti, Giuseppe, Colas, Romain A., Vulliamy, Paul, Brohi, Karim, Dalli, Jesmond, Collino, Massimo, Thiemermann, Christoph

Source: Annals of surgery. 273(5):1012-1021

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121717998.0x000001&indx=1&recIds=ETOCvdc_100121717998.0x000001

RETRACTED: Baricitinib protects mice from sepsis-induced cardiac dysfunction and multiple-organ failure.

Authors: Verra, Chiara, Mohammad, Shireen, Alves, Gustavo Ferreira, Porchietto, Elisa, Coldewey, Sina Maren, Collino, Massimo, Thiemermann, Christoph

Source: Frontiers in Immunology; 2024, p1-11, 11p

Subject Terms: SEPTIC shock, WESTERN immunoblotting, BARICITINIB, HEART diseases, SURGICAL complications

Spleen tyrosine kinase: a novel pharmacological target for sepsis-induced cardiac dysfunction and multi-organ failure.

Authors: Verra, Chiara, Paulmann, Maria Kerstin, Wegener, Jamila, Marzani, Enrica, Ferreira Alves, Gustavo, Collino, Massimo, Coldewey, Sina Maren, Thiemermann, Christoph

Source: Frontiers in Immunology; 2024, p1-16, 16p

Subject Terms: PROTEIN-tyrosine kinases, HEART diseases, INFLAMMATORY mediators, MULTIPLE organ failure, CYTOKINE release syndrome

Baricitinib counteracts metaflammation, thus protecting against diet-induced metabolic abnormalities in mice

Authors: Collotta, Debora, Hull, William, Mastrocola, Raffaella, Chiazza, Fausto, Cento, Alessia Sofia, Murphy, Catherine, Verta, Roberta, Alves, Gustavo Ferreira, Gaudioso, Giulia, Fava, Francesca, Yaqoob, Magdi, Aragno, Manuela, Tuohy, Kieran, Thiemermann, Christoph, Collino, Massimo

Source: In Molecular Metabolism September 2020 39

Inhibition of Bruton's TK regulates macrophage NF‐κB and NLRP3 inflammasome activation in metabolic inflammation

Authors: Purvis, Gareth S.D., Collino, Massimo, Aranda‐Tavio, Haidee, Chiazza, Fausto, O'Riordan, Caroline E., Zeboudj, Lynda, Mohammad, Shireen, Collotta, Debora, Verta, Roberta, Guisot, Nicolas E.S., Bunyard, Peter, Yaqoob, Magdi M., Greaves, David R., Thiemermann, Christoph

Source: British journal of pharmacology. 177(19):4416-4432

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100107970123.0x000001&indx=1&recIds=ETOCvdc_100107970123.0x000001

The hidden role of NLRP3 inflammasome in obesity‐related COVID‐19 exacerbations: Lessons for drug repurposing

Authors: Bertocchi, Ilaria, Foglietta, Federica, Collotta, Debora, Eva, Carola, Brancaleone, Vincenzo, Thiemermann, Christoph, Collino, Massimo

Source: British journal of pharmacology. 177(21):4921-4930

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108626528.0x000001&indx=1&recIds=ETOCvdc_100108626528.0x000001

Exploring extra dimensions to capture saliva metabolite fingerprints from metabolically healthy and unhealthy obese patients by comprehensive two-dimensional gas chromatography featuring Tandem Ionization mass spectrometry

Authors: Cialiè Rosso, Marta, Stilo, Federico, Squara, Simone, Liberto, Erica, Mai, Stefania, Mele, Chiara, Marzullo, Paolo, Aimaretti, Gianluca, Reichenbach, Stephen E., Collino, Massimo, Bicchi, Carlo, Cordero, Chiara

Source: Analytical and bioanalytical chemistry. 413(2):403-418

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191439233.0x000001&indx=1&recIds=ETOCvdc_100191439233.0x000001

Advanced glycation end products (AGEs) in oral pathology

Authors: Ilea, Aranka, Băbţan, Anida M., Boşca, Bianca A., Crişan, Maria, Petrescu, Nausica B., Collino, Massimo, Sainz, Rosa M., Gerlach, Jared Q., Câmpian, Radu Septimiu

Source: In Archives of Oral Biology September 2018 93:22-30