Vaping-Induced Proteolysis Causes Airway Surface Dehydration.

Authors: Ghosh, Arunava¹ (AUTHOR) arunava_ghosh@med.unc.edu, Coakley, Raymond D.² (AUTHOR) ray_coakley@med.unc.edu, Alexis, Neil E.³ (AUTHOR) neil_alexis@med.unc.edu, Tarran, Robert⁴ (AUTHOR) rtarran@kumc.edu

Source: International Journal of Molecular Sciences. Oct2023, Vol. 24 Issue 20, p15348. 15p.

Subject Terms: *PROTEASE inhibitors, *CHRONIC obstructive pulmonary disease, *LEUKOCYTE elastase, *PROTEOLYSIS, *NEUTROPHILS, *DEHYDRATION, *SODIUM channels

Chronic E-Cigarette Exposure Alters Human Alveolar Macrophage Morphology and Gene Expression

Authors: Davis, Eric S, Ghosh, Arunava, Coakley, Raymond D, Wrennall, Joe A, Lubamba, Bob A, Rowell, Temperance R, Dang, Hong, Pawlak, Erica A, Li, Quefeng, Alexis, Neil E, Ribeiro, Carla M P, Tarran, Robert

Source: Nicotine & tobacco research. 24(3):395-399

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100148559141.0x000001&indx=1&recIds=ETOCvdc_100148559141.0x000001

Use of elexacaftor/tezacaftor/ivacaftor in liver transplant patients with cystic fibrosis

Authors: McKinzie, Cameron J., Doligalski, Christina T., Lobritto, Steven J., Coakley, Raymond D., Gower, W. Adam

Source: Journal of cystic fibrosis. 21(2):227-229

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100157669639.0x000001&indx=1&recIds=ETOCvdc_100157669639.0x000001

Chronic E-Cigarette Use Increases Neutrophil Elastase and Matrix Metalloprotease Levels in the Lung

Authors: Ghosh, Arunava, Coakley, Raymond D., Ghio, Andrew J., Muhlebach, Marianne S., Esther, Charles R., Alexis, Neil E., Tarran, Robert

Source: American journal of respiratory and critical care medicine. 200(11):1392-1401

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622382190&indx=1&recIds=ETOCRN622382190

Abnormal Surface Liquid pH Regulation by Cultured Cystic Fibrosis Bronchial Epithelium

Authors: Coakley, Raymond D., Grubb, Barbara R., Paradiso, Anthony M., Gatzy, John T., Johnson, Larry G., Kreda, Sylvia M., O'Neal, Wanda K., Boucher, Richard C.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2003 Dec . 100(26), 16083-16088.

Access URL: https://www.jstor.org/stable/3149134

Mucus Hydration in Subjects with Stable Chronic Bronchitis: A Comparison of Spontaneous and Induced Sputum

Authors: Henderson, Ashley G., Anderson, Wayne H., Ceppe, Agathe, Coakley, Raymond D., Button, Brian, Alexis, Neil E., Peden, David B., Lazarowski, Eduardo R., Davis, C. W., Fuller, Fred, Almond, Martha, Qaqish, Bahjat, Kesimer, Mehmet, Boucher, Richard C.

Source: COPD. 15(6):572-580

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100105364006.0x000001&indx=1&recIds=ETOCvdc_100105364006.0x000001

Metabolomic Evaluation of Neutrophilic Airway Inflammation in Cystic Fibrosis

Authors: Esther, Charles R., Jr, Coakley, Raymond D., Henderson, Ashley G., Zhou, Yi-Hui, Wright, Fred A., Boucher, Richard C.

Source: In Chest August 2015 148(2):507-515

Outcomes Following Lung Transplant for COVID-19–Related Complications in the US.

Authors: Tasoudis, Panagiotis, Lobo, Leonard J., Coakley, Raymond D., Agala, Chris B., Egan, Thomas M., Haithcock, Benjamin E., Mody, Gita N., Long, Jason M.

Source: JAMA Surgery; Nov2023, Vol. 158 Issue 11, p1159-1166, 8p

Molecular basis for pH-dependent mucosal dehydration in cystic fibrosis airways

Authors: Garland, Alaina L., Walton, William G., Coakley, Raymond D., Tan, Chong D., Gilmore, Rodney C., Hobbs, Carey A., Tripathy, Ashutosh, Clunes, Lucy A., Bencharit, Sompop, Stutts, M. Jackson, Betts, Laurie, Redinbo, Matthew R., Tarran, Robert

Source: Proceedings of the National Academy of Sciences of the United States of America, 2013 Oct 01. 110(40), 15973-15978.

Access URL: https://www.jstor.org/stable/23749698

A Prospective Multicenter Study of Competency Metrics and Educational Interventions in the Learning of Bronchoscopy Among New Pulmonary Fellows

Authors: Wahidi, Momen M., Silvestri, Gerard A., Coakley, Raymond D., Ferguson, J. Scott, Shepherd, R. Wesley, Moses, Leonard, Conforti, John, Que, Loretta G., Anstrom, Kevin J., McGuire, Franklin, Colt, Henri, Downie, Gordon H.

Source: In Chest May 2010 137(5):1040-1049

Burkholderia gladioli: Five year experience in a cystic fibrosis and lung transplantation center

Authors: Kennedy, Marcus P., Coakley, Raymond D., Donaldson, Scott H., Aris, Robert M., Hohneker, Kathy, Wedd, Joel P., Knowles, Michael R., Gilligan, Peter H., Yankaskas, James R.

Source: In Journal of Cystic Fibrosis 2007 6(4):267-273

Chronic E-Cigarette Exposure Alters Human Alveolar Macrophage Morphology and Gene Expression.

Authors: Davis, Eric S, Ghosh, Arunava, Coakley, Raymond D, Wrennall, Joe A, Lubamba, Bob A, Rowell, Temperance R, Dang, Hong, Pawlak, Erica A, Li, Quefeng, Alexis, Neil E, Ribeiro, Carla M P, Tarran, Robert

Source: Nicotine & Tobacco Research; Mar2022, Vol. 24 Issue 3, p395-399, 5p

Subject Terms: GENE expression, ELECTRONIC cigarettes, NITRIC-oxide synthases, ALVEOLAR macrophages, MACROPHAGES

Combustible and Electronic Cigarette Exposures Increase ACE2 Activity and SARS-CoV-2 Spike Binding.

Authors: Ghosh, Arunava, Girish, Vishruth, Yuan, Monet Lou, Coakley, Raymond D., Wrennall, Joe A., Alexis, Neil E., Sausville, Erin L., Vasudevan, Anand, Chait, Alexander R., Sheltzer, Jason M., Tarran, Robert

Source: American Journal of Respiratory & Critical Care Medicine; 1/1/2022, Vol. 205 Issue 1, p129-133, 5p

Subject Terms: ELECTRONIC cigarettes, PHYSIOLOGICAL effects of tobacco, CORONAVIRUS diseases, DISEASE risk factors, ANGIOTENSIN converting enzyme, TOBACCO use

Lipid-laden Macrophages Are Not Unique to Patients with E-Cigarette or Vaping Product Use-associated Lung Injury.

Authors: Ghosh, Arunava, Ahmad, Saira, Coakley, Raymond D., Sassano, M. Flori, Alexis, Neil E., Tarran, Robert

Source: American Journal of Respiratory & Critical Care Medicine; 4/15/2021, Vol. 203 Issue 8, p1030-1033, 4p

Subject Terms: ELECTRONIC cigarettes, LUNG injury treatment, PNEUMONIA

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Polarized distribution of HCO3⁻ transport in human normal and cystic fibrosis nasal epithelia.

Authors: Paradiso, Anthony M., Coakley, Raymond D., Boucher, Richard C.

Source: Journal of Physiology; Apr2003, Vol. 548 Issue 1, p203-218, 16p

Polarized distribution of HCO3−transport in human normal and cystic fibrosis nasal epithelia

Authors: Paradiso, Anthony M., Coakley, Raymond D., Boucher, Richard C.

Source: Journal of Physiology; April 2003, Vol. 548 Issue: 1 p203-218, 16p

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