Assessment of the physiological effects and safety of transpulmonary chemoembolization with doxorubicin on pulmonary tissue using a human-isolated lung perfusion model

Authors: Alexis Slama, Hannah Steinberg, Stéphane Collaud, Özlem Okumus, Ralph-Axel Hilger, Sebastian Bauer, Hans-Ulrich Schildhaus, Clemens Aigner, Benedikt M. Schaarschmidt

Source: European Radiology Experimental, Vol 8, Iss 1, Pp 1-12 (2024)

Subject Terms: Degradable starch microspheres, Embolization (therapeutic), Lung, Perfusion, Sarcoma, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: https://doaj.org/toc/2509-9280

Access URL: https://doaj.org/article/7c10f7004cdb48e0b06cddb12706ab5c

Impact of Neoadjuvant and Adjuvant Pleural Intensity‐Modulated Radiotherapy in Multimodality Treatment for Malignant Pleural Mesothelioma

Authors: Berta Mosleh, Stefan Schwarz, Anna Cho, Katharina Sinn, Ariane Steindl, Sabine Zöchbauer‐Müller, Wolfgang J. Köstler, Karin Dieckmann, Martin Heilmann, Joachim Widder, Daniela Gompelmann, Clemens Aigner, Thomas Klikovits, Mir Alireza Hoda

Source: Thoracic Cancer, Vol 16, Iss 5, Pp n/a-n/a (2025)

Subject Terms: intensity‐modulated radiotherapy (IMRT), macroscopic complete resection, multimodality treatment, pleural mesothelioma, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714

Access URL: https://doaj.org/article/fdf6876db3e34cb293f1ae8c7d570714

High circulating activin A plasma levels are associated with tumour stage and poor survival in treatment-naive lung squamous cell cancer patients

Authors: Katharina Sinn, Ahmed Elbeialy, Berta Mosleh, Clemens Aigner, Karin Schelch, Viktoria Laszlo, Balazs Dome, Mir Alireza Hoda, Michael Grusch

Source: Translational Oncology, Vol 51, Iss , Pp 102153- (2025)

Subject Terms: Lung squamous cell carcinoma, Activin A, Biomarker, Prognostic factor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1936523324002808; https://doaj.org/toc/1936-5233

Access URL: https://doaj.org/article/5a6c99cb1bc046fea8c687bd4b6e092d

European Society of Organ Transplantation (ESOT) Consensus Statement on Machine Perfusion in Cardiothoracic Transplant

Authors: Cristiano Amarelli, Irene Bello, Clemens Aigner, Marius Berman, Massimo Boffini, Stephen Clark, Marita Dalvindt, Julien de Wolf, Stephan Ensminger, David Gomez de Antonio, Lucas Hoyos, Lucrezia Palmieri, Martin Schweiger, Sandro Sponga, Bettina Wiegmann, Arne Neyrinck, the ESOT Guidelines Taskforce

Source: Transplant International, Vol 37 (2024)

Subject Terms: machine perfusion, ex-situ heart perfusion, ex-situ lung perfusion, graft preservation, cardio-thoracic transplantation, Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: https://www.frontierspartnerships.org/articles/10.3389/ti.2024.13112/full; https://doaj.org/toc/1432-2277

Access URL: https://doaj.org/article/d9298245c370489ab67bd9fd9c35a59d

C-reactive protein as robust laboratory value associated with prognosis in patients with stage III non-small cell lung cancer (NSCLC) treated with definitive radiochemotherapy

Authors: Cedric Richlitzki, Marcel Wiesweg, Martin Metzenmacher, Nika Guberina, Christoph Pöttgen, Hubertus Hautzel, Wilfried E. E. Eberhardt, Kaid Darwiche, Dirk Theegarten, Clemens Aigner, Servet Bölükbas, Martin Schuler, Martin Stuschke, Maja Guberina

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)

Subject Terms: C-reactive protein (CRP), Stage III non-small cell lung cancer (NSCLC), Definitive radiochemotherapy, Laboratory values, Overall survival, ESPATUE trial, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/c8243a90e5a541ae931116cd6ed812f4

Transcriptional profiling sheds light on the fibrotic aspects of idiopathic subglottic tracheal stenosis

Authors: Martin Direder, Maria Laggner, Dragan Copic, Katharina Klas, Daniel Bormann, Thomas Schweiger, Konrad Hoetzenecker, Clemens Aigner, Hendrik Jan Ankersmit, Michael Mildner

Source: Frontiers in Cell and Developmental Biology, Vol 12 (2024)

Subject Terms: idiopathic subglottic stenosis, trachea, matrix, fibroblasts, plasma cells, Schwann cells, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2024.1380902/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/351268f83221412ca5292bfdc964b1dd

Small cells – big issues: biological implications and preclinical advancements in small cell lung cancer

Authors: Anna Solta, Büsra Ernhofer, Kristiina Boettiger, Zsolt Megyesfalvi, Simon Heeke, Mir Alireza Hoda, Christian Lang, Clemens Aigner, Fred R. Hirsch, Karin Schelch, Balazs Döme

Source: Molecular Cancer, Vol 23, Iss 1, Pp 1-25 (2024)

Subject Terms: Small cell lung cancer, Molecular subtypes, Translational progress, Preclinical models, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1476-4598

Access URL: https://doaj.org/article/9e0908a3548240cd8b1b9b99d893d136

C-Myc protein expression indicates unfavorable clinical outcome in surgically resected small cell lung cancer

Authors: Christian Lang, Zsolt Megyesfalvi, Andras Lantos, Felicitas Oberndorfer, Mir Alireza Hoda, Anna Solta, Bence Ferencz, Janos Fillinger, Anna Solyom-Tisza, Alessandro Saeed Querner, Felix Egger, Kristiina Boettiger, Thomas Klikovits, Gerald Timelthaler, Ferenc Renyi-Vamos, Clemens Aigner, Konrad Hoetzenecker, Viktoria Laszlo, Karin Schelch, Balazs Dome

Source: World Journal of Surgical Oncology, Vol 22, Iss 1, Pp 1-12 (2024)

Subject Terms: Small cell lung cancer, Myc family, Molecular subtypes, Immunohistochemistry, Surgery, RD1-811, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1477-7819

Access URL: https://doaj.org/article/234161e89df04bc49487dd2d775855f8

Resectable non-stage IV nonsmall cell lung cancer: the surgical perspective

Authors: Clemens Aigner, Hasan Batirel, Rudolf M. Huber, David R. Jones, Alan D.L. Sihoe, Tomaž Štupnik, Alessandro Brunelli

Source: European Respiratory Review, Vol 33, Iss 171 (2024)

Subject Terms: Diseases of the respiratory system, RC705-779

File Description: electronic resource

Relation: http://err.ersjournals.com/content/33/171/230195.full; https://doaj.org/toc/0905-9180; https://doaj.org/toc/1600-0617

Access URL: https://doaj.org/article/2463c732387d4ae4aac9d310a2ae1853

Prediction of malignant lymph nodes in NSCLC by machine-learning classifiers using EBUS-TBNA and PET/CT

Authors: Maja Guberina, Ken Herrmann, Christoph Pöttgen, Nika Guberina, Hubertus Hautzel, Thomas Gauler, Till Ploenes, Lale Umutlu, Axel Wetter, Dirk Theegarten, Clemens Aigner, Wilfried E. E. Eberhardt, Martin Metzenmacher, Marcel Wiesweg, Martin Schuler, Rüdiger Karpf-Wissel, Alina Santiago Garcia, Kaid Darwiche, Martin Stuschke

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/14b9b81885214e0fa30e5e06cd507ee7

The clinical utility of cfRNA for disease detection and surveillance: A proof of concept study in non‐small cell lung cancer

Authors: Martin Metzenmacher, Balazs Hegedüs, Jan Forster, Alexander Schramm, Peter A. Horn, Christoph A. Klein, Nicola Bielefeld, Till Ploenes, Clemens Aigner, Jens T. Siveke, Martin Schuler, Smiths S. Lueong

Source: Thoracic Cancer, Vol 13, Iss 15, Pp 2180-2191 (2022)

Subject Terms: cfRNA, ddPCR, liquid biopsy, NGS, NSCLC, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714

Access URL: https://doaj.org/article/2636748d7c9c455babf6ed2f5ee009ba

Long-term survival of patients with central or > 7 cm T4 N0/1 M0 non-small-cell lung cancer treated with definitive concurrent radiochemotherapy in comparison to trimodality treatment

Authors: Nika Guberina, Christoph Pöttgen, Martin Schuler, Maja Guberina, Georgios Stamatis, Till Plönes, Martin Metzenmacher, Dirk Theegarten, Thomas Gauler, Kaid Darwiche, Clemens Aigner, Wilfried E. E. Eberhardt, Martin Stuschke

Source: Radiation Oncology, Vol 17, Iss 1, Pp 1-14 (2022)

Subject Terms: Definitive radiochemotherapy, Non-small cell lung cancer, TNM-staging, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1748-717X

Access URL: https://doaj.org/article/00af72a665cd4af79ce9d0e8fcbce687

Coronavirus Receptor Expression Profiles in Human Mast Cells, Basophils, and Eosinophils

Authors: Lina Degenfeld-Schonburg, Irina Sadovnik, Dubravka Smiljkovic, Barbara Peter, Gabriele Stefanzl, Clemens Gstoettner, Peter Jaksch, Konrad Hoetzenecker, Clemens Aigner, Christine Radtke, Michel Arock, Wolfgang R. Sperr, Peter Valent

Source: Cells, Vol 13, Iss 2, p 173 (2024)

Subject Terms: mast cells, basophils, eosinophils, SARS-CoV-2 receptors, inflammation, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/13/2/173; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/8ffa1bea4f2941df83cfec08e91f6328

Reversible occlusion of the pulmonary vasculature by transarterial embolisation with degradable starch microspheres: preclinical assessment in a human isolated lung perfusion model

Authors: Benedikt M. Schaarschmidt, Alexis Slama, Stéphane Collaud, Özlem Okumus, Hannah Steinberg, Sebastian Bauer, Hans-Ulrich Schildhaus, Jens Theysohn, Clemens Aigner

Source: European Radiology Experimental, Vol 6, Iss 1, Pp 1-11 (2022)

Subject Terms: alpha-Amylases, Degradable starch microspheres, Lung neoplasms, Perfusion imaging, Tomography (x-ray computed), Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: https://doaj.org/toc/2509-9280

Access URL: https://doaj.org/article/b443f183da9d43eabe3b2bf04fd99037

Atypical bilateral ventilation/perfusion mismatches in an asymptomatic patient suffering from metastatic thyroid cancer

Authors: David Kersting, Christoph Rischpler, Till Plönes, Clemens Aigner, Lale Umutlu, Ken Herrmann, Hubertus Hautzel

Source: European Journal of Hybrid Imaging, Vol 5, Iss 1, Pp 1-5 (2021)

Subject Terms: Perfusion scintigraphy, MAA SPECT, Pulmonary embolism, Thyroid cancer, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: https://doaj.org/toc/2510-3636

Access URL: https://doaj.org/article/7247ca7d2d2045618f151385c27f9908

Patterns of nodal spread in stage III NSCLC: importance of EBUS-TBNA and 18F-FDG PET/CT for radiotherapy target volume definition

Authors: Maja Guberina, Kaid Darwiche, Hubertus Hautzel, Christoph Pöttgen, Nika Guberina, Thomas Gauler, Till Ploenes, Lale Umutlu, Dirk Theegarten, Clemens Aigner, Wilfried E. E. Eberhardt, Martin Metzenmacher, Marcel Wiesweg, Rüdiger Karpf-Wissel, Martin Schuler, Ken Herrmann, Martin Stuschke

Source: Radiation Oncology, Vol 16, Iss 1, Pp 1-12 (2021)

Subject Terms: NSCLC, Stage III, Lymphatic drainage, Pattern of spread, 18F-FDG PET/CT, EBUS-TBNA, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1748-717X

Access URL: https://doaj.org/article/37ec946feda8468ea3b10b141aa40bbe

N-staging in large cell neuroendocrine carcinoma of the lung: diagnostic value of [18F]FDG PET/CT compared to the histopathology reference standard

Authors: Hubertus Hautzel, Yazan Alnajdawi, Wolfgang P. Fendler, Christoph Rischpler, Kaid Darwiche, Wilfried E. Eberhardt, Lale Umutlu, Dirk Theegarten, Martin Stuschke, Martin Schuler, Clemens Aigner, Ken Herrmann, Till Plönes

Source: EJNMMI Research, Vol 11, Iss 1, Pp 1-9 (2021)

Subject Terms: [18F]FDG, PET/CT, Large cell neuroendocrine carcinoma, Lung, Nodal staging, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: https://doaj.org/toc/2191-219X

Access URL: https://doaj.org/article/084f39ecd15a4dfbbb4deb425b97b489

Number of metastases and their response to chemotherapy impact survival of patients with isolated lung metastases from bone-derived sarcoma

Authors: Theresa Stork, Rebecca Boemans, Jendrik Hardes, Arne Streitbürger, Uta Dirksen, Christoph Pöttgen, Hans-Ulrich Schildhaus, Sebastian Bauer, Stéphane Collaud, Clemens Aigner

Source: BMC Cancer, Vol 21, Iss 1, Pp 1-7 (2021)

Subject Terms: Pulmonary metastasectomy, Bone sarcoma, Lung metastases, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/cbea41d6fb6447c5ba12f752307bf383

Nintedanib and Dasatinib Treatments Induce Protective Autophagy as a Potential Resistance Mechanism in MPM Cells

Authors: Luca Hegedüs, Kata D. Szücs, Matthias Kudla, Julian Heidenreich, Verena Jendrossek, Samuel Peña-Llopis, Tamas Garay, Andras Czirok, Clemens Aigner, Till Plönes, Silvia Vega-Rubin-de-Celis, Balazs Hegedüs

Source: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Subject Terms: malignant pleural mesothelioma, autophagy, TFEB, nintedanib, dasatinib, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2022.852812/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/bdcebd8073a4423daa0b8b32f489f9af

Combined multimodal ctDNA analysis and radiological imaging for tumor surveillance in Non-small cell lung cancer

Authors: Martin Metzenmacher, Balazs Hegedüs, Jan Forster, Alexander Schramm, Peter A. Horn, Christoph A. Klein, Nicola Bielefeld, Till Ploenes, Clemens Aigner, Dirk Theegarten, Hans-Ulrich Schildhaus, Jens T. Siveke, Martin Schuler, Smiths S. Lueong

Source: Translational Oncology, Vol 15, Iss 1, Pp 101279- (2022)

Subject Terms: Lung cancer, ddPCR, NGS, cfDNA methylation, Surveillance, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1936523321002709; https://doaj.org/toc/1936-5233

Access URL: https://doaj.org/article/d3b1076963f443d6a11522f1b04db4d4