NLS-binding deficient Kapβ2 reduces neurotoxicity via selective interaction with C9orf72-ALS/FTD dipeptide repeats.

Authors: Kim, Kevin M., Girdhar, Amandeep, Cicardi, Maria E., Kankate, Vaishnavi, Hayashi, Miyuki, Yang, Ruoyu, Carey, Jenny L., Fare, Charlotte M., Shorter, James, Cingolani, Gino, Trotti, Davide, Guo, Lin

Source: Communications Biology; 1/2/2025, Vol. 8 Issue 1, p1-20, 20p

Subject Terms: PHASE transitions, AMYOTROPHIC lateral sclerosis, STRESS granules, RNA-binding proteins, FRONTOTEMPORAL dementia

Pathogenic variants of Valosin‐containing protein induce lysosomal damage and transcriptional activation of autophagy regulators in neuronal cells

Authors: Ferrari, Veronica, Cristofani, Riccardo, Cicardi, Maria E., Tedesco, Barbara, Crippa, Valeria, Chierichetti, Marta, Casarotto, Elena, Cozzi, Marta, Mina, Francesco, Galbiati, Mariarita, Piccolella, Margherita, Carra, Serena, Vaccari, Thomas, Nalbandian, Angele, Kimonis, Virginia, Fortuna, Tyler R., Pandey, Udai B., Gagliani, Maria C., Cortese, Katia, Rusmini, Paola, Poletti, Angelo

Source: Neuropathology & applied neurobiology. 48(5)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100154994028.0x000001&indx=1&recIds=ETOCvdc_100154994028.0x000001

JUN upregulation drives aberrant transposable element mobilization, associated innate immune response, and impaired neurogenesis in Alzheimer’s disease.

Authors: Scopa, Chiara, Barnada, Samantha M., Cicardi, Maria E., Singer, Mo, Trotti, Davide, Trizzino, Marco

Source: Nature Communications; 12/4/2023, Vol. 14 Issue 1, p1-16, 16p

Loss of PML nuclear bodies in familial amyotrophic lateral sclerosis-frontotemporal dementia.

Authors: Antoniani, Francesco, Cimino, Marco, Mediani, Laura, Vinet, Jonathan, Verde, Enza M., Secco, Valentina, Yamoah, Alfred, Tripathi, Priyanka, Aronica, Eleonora, Cicardi, Maria E., Trotti, Davide, Sterneckert, Jared, Goswami, Anand, Carra, Serena

Source: Cell Death Discovery; 7/15/2023, Vol. 9 Issue 1, p1-16, 16p

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.