ΔNp63/p73 drive metastatic colonization by controlling a regenerative epithelial stem cell program in quasi-mesenchymal cancer stem cells

Authors: Lambert, Arthur W., Fiore, Christopher, Chutake, Yogesh, Verhaar, Elisha R., Strasser, Patrick C., Chen, Mei Wei, Farouq, Daneyal, Das, Sunny, Li, Xin, Eaton, Elinor Ng, Zhang, Yun, Liu Donaher, Joana, Engstrom, Ian, Reinhardt, Ferenc, Yuan, Bingbing, Gupta, Sumeet, Wollison, Bruce, Eaton, Matthew, Bierie, Brian, Carulli, John, Olson, Eric R., Guenther, Matthew G., Weinberg, Robert A.

Source: In Developmental Cell 19 December 2022 57(24):2714-2730

The Cerebellar Cognitive Affective Syndrome in Ataxia-Telangiectasia

Authors: Hoche, Franziska, Daly, Maureen P., Chutake, Yogesh K., Valera, Eve, Sherman, Janet C., Schmahmann, Jeremy D.

Source: Cerebellum. 18(2):225-244

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100124736899.0x000001&indx=1&recIds=ETOCvdc_100124736899.0x000001

Altered Nucleosome Positioning at the Transcription Start Site and Deficient Transcriptional Initiation in Friedreich Ataxia

Authors: Chutake, Yogesh K., Costello, Whitney N., Lam, Christina, Bidichandani, Sanjay I.

Source: In Journal of Biological Chemistry 30 May 2014 289(22):15194-15202

A STAT3 Degrader Demonstrates Pre-Clinical Efficacy in Venetoclax Resistant Acute Myeloid Leukemia

Authors: Chakraborty, Samarpana, Morganti, Claudia, Dey, Joyoti, Zhang, Hui, Aluri, Srinivas, Gitego, Nadege, Pradhan, Kith, Rivera, Bianca, Chutake, Yogesh, Skwarska, Anna, Mantzaris, Ioannis, Goldfinger, Mendel, Feldman, Eric J, Choudhary, Gaurav S, Hubner, Stefan, Qiu, Yihua, Brown, Brandon D., Verma, Amit, Gavathiotis, Evripidis, Konopleva, Marina Y., Kornblau, Steven M., Gollob, Jared, Ito, Keisuke, Shastri, Aditi

Source: In Blood 2 November 2023 142 Supplement 1:2787-2787

Development of KT-253, a Highly Potent and Selective Heterobifunctional MDM2 Degrader for the Treatment of Acute Myeloid Leukemia

Authors: Mayo, Michele ^*, Chutake, Yogesh ^*, Karnik, Rahul ^*, McDonald, Alice ^*, Cho, Patricia S. ^*, Filiatrault, Jessica ^*, Chen, Dapeng ^*, Dixit, Vaishali ^*, Proctor, William ^*, Breitkopf, Susanne ^*, Qi, Frank ^*, Hu, Kan-Nian ^*, Sharma, Kirti ^*, Ewesuedo, Reggie ^*, Weiss, Matt ^*, Growney, Joseph D. ^*, Williams, Juliet ^*, Schalm, Stefanie S ^*

Source: In Blood 15 November 2022 140 Supplement 1:6239-6240

FXN Promoter Silencing in the Humanized Mouse Model of Friedreich Ataxia.

Authors: Chutake, Yogesh K.¹, Costello, Whitney N.¹, Lam, Christina C.¹, Parikh, Aniruddha C.¹, Hughes, Tamara T.¹, Michalopulos, Michael G.¹, Pook, Mark A.², Bidichandani, Sanjay I.^1,3 Sanjay-Bidichandani@ouhsc.edu

Source: PLoS ONE. 9/22/2015, Vol. 10 Issue 9, p1-12. 12p.

Subject Terms: *PROMOTERS (Genetics), *GENE silencing, *LABORATORY mice, *FRIEDREICH'S ataxia, *GENETIC transcription

Methylated and unmethylated epialleles support variegated epigenetic silencing in Friedreich ataxia.

Authors: Rodden, Layne N, Chutake, Yogesh K, Gilliam, Kaitlyn, Lam, Christina, Soragni, Elisabetta, Hauser, Lauren, Gilliam, Matthew, Wiley, Graham, Anderson, Michael P, Gottesfeld, Joel M, Lynch, David R, Bidichandani, Sanjay I

Source: Human Molecular Genetics; Dec2020, Vol. 29 Issue 23, p3818-3829, 12p

Mechanisms of the Anti-Tumor Activity of STAT3 Degraders in Lymphoma

Authors: Rong, Haojing ^*, Sharma, Kirti ^*, Csibi, Fred ^*, Yang, Bin ^*, Rusin, Scott ^*, Shi, Yatao ^*, Dey, Joyoti ^*, Karnik, Rahul ^*, Mayo, Michele ^*, Yuan, Karen ^*, Chutake, Yogesh ^*, McDonald, Alice ^*, Zhu, Sean ^*, Ji, Nan ^*, Liu, Phillip ^*, Li, Henry ^*, Walker, Duncan, Gollob, Jared ^*, Mainolfi, Nello ^*, Desavi, Chris ^*

Source: In Blood 5 November 2020 136 Supplement 1:42-42

P464: PULSE DOSING OF POTENT AND SELECTIVE HETEROBIFUNCTIONAL MDM2 DEGRADER KT‐253 DRIVES TUMOR REGRESSION AND DEMONSTRATES DIFFERENTIATED PHARMACOLOGY COMPARED TO P53/MDM2 SMALL MOLECULE INHIBITORS.

Authors: Schalm, Stefanie, Chutake, Yogesh, Breitkopf, Susanne, Mayo, Michele, Dumont, Nancy, Chen, Dapeng, Dixit, Vaishali, Karnik, Rahul, Mcdonald, Alice, Filiatrault, Jessica, Proctor, William, Qi, Frank, Hu, Kan‐Nian, Weiss, Matt, Gollerkeri, Ashwin, Sharma, Kirti, D Growney, Joseph, Williams, Juliet

Source: HemaSphere; 2023 Supplement 3, Vol. 7, p1-2, 2p

The Cerebellar Cognitive Affective Syndrome in Ataxia-Telangiectasia.

Authors: Hoche, Franziska, Daly, Maureen P., Chutake, Yogesh K., Valera, Eve, Sherman, Janet C., Schmahmann, Jeremy D.

Source: Cerebellum; Apr2019, Vol. 18 Issue 2, p225-244, 20p

Subject Terms: SOCIAL perception, AGE groups, CEREBELLAR ataxia, YOUNG adults, DYSLEXIA, AUDITORY processing disorder, AGE factors in disease, ACALCULIA

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A novel GAA-repeat-expansion-based mouse model of Friedreich’s ataxia

Authors: Anjomani Virmouni, Sara, Ezzatizadeh, Vahid, Sandi, Chiranjeevi, Sandi, Madhavi, Al-Mahdawi, Sahar, Chutake, Yogesh, Pook, Mark A.

Source: Disease Models and Mechanisms; March 2015, Vol. 8 Issue: 3 p225-235, 11p

RNA-mediated transcriptional gene silencing in Friedreich ataxia

Authors: Bidichandani, Sanjay, Castro, Angela, Chutake, Yogesh

Source: In Current Opinion in Biotechnology 2011 22 Supplement 1:S16-S16