mRNA‐Engineered CD5‐CAR‐γδTCD5‐ Cells for the Immunotherapy of T‐Cell Acute Lymphoblastic Leukemia

Authors: Zhixiong Zhu, Hexian Li, Qizhong Lu, Zongliang Zhang, Jia Li, Zeng Wang, Nian Yang, Zhengyu Yu, Chen Yang, Yongdong Chen, Huaqing Lu, Wei Wang, Ting Niu, Chunlai Nie, Aiping Tong

Source: Advanced Science, Vol 11, Iss 35, Pp n/a-n/a (2024)

Subject Terms: CAR‐T, IVT‐mRNA, T‐ALL, γδT cells, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/8b15ce605dcc484b9a66e75fbf9aa14f

Kidney microbiota dysbiosis contributes to the development of hypertension

Authors: Xin-Yu Liu, Jing Li, Yamei Zhang, Luyun Fan, Yanli Xia, Yongyang Wu, Junru Chen, Xinyu Zhao, Qiannan Gao, Bing Xu, Chunlai Nie, Zhengyu Li, Aiping Tong, Wenjie Wang, Jun Cai

Source: Gut Microbes, Vol 14, Iss 1 (2022)

Subject Terms: Gut microbiota translocation, kidney microbiota, cell-wall-deficient bacteria, L-form bacteria, sIgA-coated bacteria, IgA protease, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1949-0976; https://doaj.org/toc/1949-0984

Access URL: https://doaj.org/article/884580b40c884b8cbf2a78205d415ea6

Development of multivalent nanobodies blocking SARS-CoV-2 infection by targeting RBD of spike protein

Authors: Qizhong Lu, Zongliang Zhang, Hexian Li, Kunhong Zhong, Qin Zhao, Zeng Wang, Zhiguo Wu, Donghui Yang, Shuang Sun, Nian Yang, Meijun Zheng, Qiang Chen, Cheng Long, Wenhao Guo, Hui Yang, Chunlai Nie, Aiping Tong

Source: Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-12 (2021)

Subject Terms: SARS-CoV-2, Nanobody, Spike, RBD, Pseudovirus neutralization, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/ee69c52085444c6b9cd52344715bcbc2

Genome-scale CRISPR–Cas9 screen reveals novel regulators of B7-H3 in tumor cells

Authors: Hui Yang, Gang Guo, Min Mu, Xi Zheng, Yuelong Wang, Ting Cao, Shasha Zhao, Cheng Huang, Xin Tang, Guoqing Wang, Nian Yang, Zhiguo Wu, Hexian Li, Kunhong Zhong, Zongliang Zhang, Meijun Zheng, Chunlai Nie, Liangxue Zhou, Aiping Tong

Source: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/10/6/e004875.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/64030ae3e92d443cbe06e27db71987b7

Evaluation of B7-H3 Targeted Immunotherapy in a 3D Organoid Model of Craniopharyngioma

Authors: Mei Tang, Caili Chen, Guoqing Wang, Yuelong Wang, Zongliang Zhang, Hexian Li, Qizhong Lu, Zeng Wang, Shasha Zhao, Chen Yang, Kunhong Zhong, Ruyuan Zhang, Liping Guo, Zhu Yuan, Chunlai Nie, Aiping Tong

Source: Biomolecules, Vol 12, Iss 12, p 1744 (2022)

Subject Terms: craniopharyngioma, B7-H3, organoid, immunotherapy, brain cancer, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-273X/12/12/1744; https://doaj.org/toc/2218-273X

Access URL: https://doaj.org/article/59b47f0e29904f10a29c1c8ef0530947

Intercellular Adhesion Molecule-1 as Target for CAR-T-Cell Therapy of Triple-Negative Breast Cancer

Authors: Heng Wei, Zeng Wang, Yi Kuang, Zhiguo Wu, Shasha Zhao, Zongliang Zhang, Hexian Li, Meijun Zheng, Nan Zhang, Cheng Long, Wenhao Guo, Chunlai Nie, Hui Yang, Aiping Tong

Source: Frontiers in Immunology, Vol 11 (2020)

Subject Terms: triple-negative breast cancer, intercellular adhesion molecule-1, chimeric antigen receptor T cells, immunotherapy, single chain variable fragment, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.573823/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/c470d526e078448c9eaaf71de2f39146

Structural and Mechanistic Analyses Reveal a Unique Cas4-like Protein in the Mimivirus Virophage Resistance Element System

Authors: Chao Dou, Mingjing Yu, Yijun Gu, Jinjing Wang, Kun Yin, Chunlai Nie, Xiaofeng Zhu, Shiqian Qi, Yuquan Wei, Wei Cheng

Source: iScience, Vol 3, Iss , Pp 1-10 (2018)

Subject Terms: Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004218300336; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/25624fde35f84394801bd4825cad2966

Long non-coding RNA SPRY4-IT1 promotes cell proliferation and invasion by regulation of Cdc20 in pancreatic cancer cells.

Authors: Wenhao Guo, Kunhong Zhong, Heng Wei, Chunlai Nie, Zhu Yuan

Source: PLoS ONE, Vol 13, Iss 2, p e0193483 (2018)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5831108?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/0fc06865e70041719f121f33908257cf

SKLB-M8 Induces Apoptosis Through the AKT/mTOR Signaling Pathway in Melanoma Models and Inhibits Angiogenesis With Decrease of ERK1/2 Phosphorylation

Authors: Jingjing Wang, Zhuang Yang, Jiaolin Wen, Feng Ma, Fang Wang, Kun Yu, Minghai Tang, Wenshuang Wu, Yinfeng Dong, Xia Cheng, Chunlai Nie, Lijuan Chen

Source: Journal of Pharmacological Sciences, Vol 126, Iss 3, Pp 198-207 (2014)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S134786131930074X; https://doaj.org/toc/1347-8613

Access URL: https://doaj.org/article/73fb9f1c0eea4d268f5a1e5375318cf0

BIM-mediated AKT phosphorylation is a key modulator of arsenic trioxide-induced apoptosis in cisplatin-sensitive and -resistant ovarian cancer cells.

Authors: Zhu Yuan, Fang Wang, Zhiwei Zhao, Xinyu Zhao, Ji Qiu, Chunlai Nie, Yuquan Wei

Source: PLoS ONE, Vol 6, Iss 5, p e20586 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3105099?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ff28025aedd240038aeaba6ac128d067

Isogambogenic acid inhibits tumour angiogenesis by suppressing Rho GTPases and vascular endothelial growth factor receptor 2 signalling pathway.

Authors: Yi Fan, Aihua Peng, Shichao He, Ximing Shao, Chunlai Nie, Lijuan Chen

Source: Journal of Chemotherapy (E.S.I.F.T. srl); Oct2013, Vol. 25 Issue 5, p298-308, 11p

JNK- and Akt-mediated Puma expression in the apoptosis of cisplatin-resistant ovarian cancer cells.

Authors: Zhiwei ZHAO, Jingjing WANG, Jingsheng TANG, Xinyu LIU, Qian ZHONG, Fang WANG, Wenbin HU, Zhu YUAN, Chunlai NIE, Yuquan WEI

Source: Biochemical Journal; 6/ 1/2012, Vol. 444 Issue 2, p291-304, 14p

Subject Terms: JNK mitogen-activated protein kinases, PROTEIN kinase B, GENE expression, APOPTOSIS, DRUG resistance in cancer cells, CISPLATIN, OVARIAN cancer

Proteomic analysis revealed association of aberrant ROS signaling with suberoylanilide hydroxamic acid-induced autophagy in jurkat T-leukemia cells.

Authors: Jingyi Li, Rui Liu, Yunlong Lei, Kui Wang, Quek Choon Lau, Na Xie, Shengtao Zhou, Chunlai Nie, Lijuan Chen, Yuquan Wei, Canhua Huang

Source: Autophagy; Aug2010, Vol. 6 Issue 6, p89-102, 14p

Cysteine 62 of Bax Is Critical for Its Conformational Activation and Its Proapoptotic Activity in Response to H2O2-induced Apoptosis.

Authors: Chunlai Nie¹, Changhai Tian¹, Lixia Zhao¹, Xavier Petit, Patrice², Mehrpour, Maryam^1,3 mehrpour@ioz.ac.cn, Quan Chen¹ chenq@ioz.ac.cn

Source: Journal of Biological Chemistry. 5/30/2008, Vol. 283 Issue 22, p15359-15368. 10p. 6 Graphs.

Subject Terms: *CYTOCHROME c, *APOPTOSIS, *MOLECULES, *CYSTEINE proteinases, *OXYGEN

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PNAS-4, an Early DNA Damage Response Gene, Induces S Phase Arrest and Apoptosis by Activating Checkpoint Kinases in Lung Cancer Cells.

Authors: Zhu Yuan¹ yuanzhu@scu.edu.cn, Wenhao Guo², Jun Yang¹, Lei Li¹, Meiliang Wang¹, Yi Lei¹, Yang Wan¹, Xinyu Zhao¹, Na Luo³, Ping Cheng¹, Xinyu Liu¹, Chunlai Nie¹, Yong Peng¹, Aiping Tong¹ aipingtong@scu.edu.cn, Yuquan Wei¹

Source: Journal of Biological Chemistry. 6/12/2015, Vol. 290 Issue 24, p14927-14944. 18p.

Subject Terms: *DNA damage, *PROTEIN kinases, *APOPTOSIS, *LUNG cancer, *CANCER cells, *GENE silencing