White matter hyperintensity volume modifies the association between CSF vascular inflammatory biomarkers and regional FDG-PET along the Alzheimer’s disease continuum

Authors: Tubi, Meral A., Wheeler, Koral, Matsiyevskiy, Elizabeth, Hapenney, Matthew, Mack, Wendy J., Chui, Helena C., King, Kevin, Thompson, Paul M., Braskie, Meredith N.

Source: In Neurobiology of Aging December 2023 132:1-12

The association between white matter hyperintensities and amyloid and tau deposition

Authors: Alban, Sierra L., Lynch, Kirsten M., Ringman, John M., Toga, Arthur W., Chui, Helena C., Sepehrband, Farshid, Choupan, Jeiran

Source: In NeuroImage: Clinical 2023 38

Microstructural mapping of dentate gyrus pathology in Alzheimer’s disease: A 16.4 Tesla MRI study

Authors: Shih, Nien-Chu, Kurniawan, Nyoman D., Cabeen, Ryan P., Korobkova, Laura, Wong, Ellen, Chui, Helena C, Clark, Kristi A., Miller, Carol A, Hawes, Debra, Jones, Kymry T., Sepehrband, Farshid

Source: In NeuroImage: Clinical 2023 37

Association of improved air quality with lower dementia risk in older women

Authors: Wang, Xinhui, Younan, Diana, Millstein, Joshua, Petkus, Andrew J., Garcia, Erika, Beavers, Daniel P., Espeland, Mark A., Chui, Helena C., Resnick, Susan M., Gatz, Margaret, Kaufman, Joel D., Wellenius, Gregory A., Whitsel, Eric A., Manson, JoAnn E., Rapp, Stephen R., Chen, Jiu-Chiuan

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Jan 01. 119(2), 1-8.

Access URL: https://www.jstor.org/stable/27112898

White matter degradation near cerebral microbleeds is associated with cognitive change after mild traumatic brain injury

Authors: Irimia, Andrei, Ngo, Van, Chaudhari, Nikhil N., Zhang, Fan, Joshi, Shantanu H., Penkova, Anita N., O'Donnell, Lauren J., Sheikh-Bahaei, Nasim, Zheng, Xiaoyu, Chui, Helena C.

Source: In Neurobiology of Aging December 2022 120:68-80

Ambient air pollution exposure and increasing depressive symptoms in older women: The mediating role of the prefrontal cortex and insula

Authors: Petkus, Andrew J., Resnick, Susan M., Wang, Xinhui, Beavers, Daniel P., Espeland, Mark A., Gatz, Margaret, Gruenewald, Tara, Millstein, Joshua, Chui, Helena C., Kaufman, Joel D., Manson, JoAnn E., Wellenius, Gregory A., Whitsel, Eric A., Widaman, Keith, Younan, Diana, Chen, Jiu-Chiuan

Source: In Science of the Total Environment 1 June 2022 823

Locus coeruleus integrity is related to tau burden and memory loss in autosomal-dominant Alzheimer's disease

Authors: Dahl, Martin J., Mather, Mara, Werkle-Bergner, Markus, Kennedy, Briana L., Guzman, Samuel, Hurth, Kyle, Miller, Carol A., Qiao, Yuchuan, Shi, Yonggang, Chui, Helena C., Ringman, John M.

Source: In Neurobiology of Aging April 2022 112:39-54

Volumetric distribution of perivascular space in relation to mild cognitive impairment

Authors: Sepehrband, Farshid, Barisano, Giuseppe, Sheikh-Bahaei, Nasim, Choupan, Jeiran, Cabeen, Ryan P., Lynch, Kirsten M., Crawford, Malcolm S., Lan, Haoyu, Mack, Wendy J., Chui, Helena C., Ringman, John M., Toga, Arthur W.

Source: In Neurobiology of Aging March 2021 99:28-43

Outdoor air pollution exposure and inter-relation of global cognitive performance and emotional distress in older women

Authors: Petkus, Andrew J., Wang, Xinhui, Beavers, Daniel P., Chui, Helena C., Espeland, Mark A., Gatz, Margaret, Gruenewald, Tara, Kaufman, Joel D., Manson, JoAnn E., Resnick, Susan M., Stewart, James D., Wellenius, Gregory A., Whitsel, Eric A., Widaman, Keith, Younan, Diana, Chen, Jiu-Chiuan

Source: In Environmental Pollution 15 February 2021 271

Reaction time and response inhibition in autosomal dominant Alzheimer’s disease

Authors: Medina, Luis D., Woo, Ellen, Rodriguez-Agudelo, Yaneth, Chaparro Maldonado, Hector, Yi, Dahyun, Coppola, Giovanni, Zhou, Yan, Chui, Helena C., Ringman, John M.

Source: In Brain and Cognition February 2021 147

Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD.

Authors: Wang, Shaowei, Li, Boyang, Li, Jie, Cai, Zhiheng, Hugo, Cristelle, Sun, Yi, Qian, Lu, TCW, Julia, Chui, Helena C., Dikeman, Dante, Asante, Isaac, Louie, Stan G., Bennett, David A., Arvanitakis, Zoe, Remaley, Alan T., Kerman, Bilal E., Yassine, Hussein N.

Source: Molecular Neurodegeneration; 2/4/2025, Vol. 20 Issue 1, p1-26, 26p

Subject Terms: CELLULAR aging, LIFE sciences, MEDICAL sciences, CYTOLOGY, PLURIPOTENT stem cells, ATP-binding cassette transporters

Brain delivery of supplemental docosahexaenoic acid (DHA): A randomized placebo-controlled clinical trial

Authors: Arellanes, Isabella C., Choe, Nicholas, Solomon, Victoria, He, Xulei, Kavin, Brian, Martinez, Ashley E., Kono, Naoko, Buennagel, David P., Hazra, Nalini, Kim, Giselle, D'Orazio, Lina M., McCleary, Carol, Sagare, Abhay, Zlokovic, Berislav V., Hodis, Howard N., Mack, Wendy J., Chui, Helena C., Harrington, Michael G., Braskie, Meredith N., Schneider, Lon S., Yassine, Hussein N.

Source: In eBioMedicine September 2020 59

Undetectable gadolinium brain retention in individuals with an age-dependent blood-brain barrier breakdown in the hippocampus and mild cognitive impairment

Authors: Montagne, Axel, Huuskonen, Mikko T., Rajagopal, Gautham, Sweeney, Melanie D., Nation, Daniel A., Sepehrband, Farshid, D'Orazio, Lina M., Harrington, Michael G., Chui, Helena C., Law, Meng, Toga, Arthur W., Zlokovic, Berislav V.

Source: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association December 2019 15(12):1568-1575

Vascular dysfunction—The disregarded partner of Alzheimer's disease

Authors: Sweeney, Melanie D., Montagne, Axel, Sagare, Abhay P., Nation, Daniel A., Schneider, Lon S., Chui, Helena C., Harrington, Michael G., Pa, Judy, Law, Meng, Wang, Danny J.J., Jacobs, Russell E., Doubal, Fergus N., Ramirez, Joel, Black, Sandra E., Nedergaard, Maiken, Benveniste, Helene, Dichgans, Martin, Iadecola, Costantino, Love, Seth, Bath, Philip M., Markus, Hugh S., Salman, Rustam A., Allan, Stuart M., Quinn, Terence J., Kalaria, Rajesh N., Werring, David J., Carare, Roxana O., Touyz, Rhian M., Williams, Steve C.R., Moskowitz, Michael A., Katusic, Zvonimir S., Lutz, Sarah E., Lazarov, Orly, Minshall, Richard D., Rehman, Jalees, Davis, Thomas P., Wellington, Cheryl L., González, Hector M., Yuan, Chun, Lockhart, Samuel N., Hughes, Timothy M., Chen, Christopher L.H., Sachdev, Perminder, O'Brien, John T., Skoog, Ingmar, Pantoni, Leonardo, Gustafson, Deborah R., Biessels, Geert Jan, Wallin, Anders, Smith, Eric E., Mok, Vincent, Wong, Adrian, Passmore, Peter, Barkof, Frederick, Muller, Majon, Breteler, Monique M.B., Román, Gustavo C., Hamel, Edith, Seshadri, Sudha, Gottesman, Rebecca F., van Buchem, Mark A., Arvanitakis, Zoe, Schneider, Julie A., Drewes, Lester R., Hachinski, Vladimir, Finch, Caleb E., Toga, Arthur W., Wardlaw, Joanna M., Zlokovic, Berislav V.

Source: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association January 2019 15(1):158-167

Urine dicarboxylic acid as a potential AD biomarker associated with fusiform gyrus volume in older cognitively healthy adults.

Authors: Fonteh, Alfred N¹ (AUTHOR) Alfred.fonteh@hmri.org, Maldonado, Salvador¹ (AUTHOR), Butler, Ryan¹ (AUTHOR), Kang, Jimmy² (AUTHOR), Macias, Thomas³ (AUTHOR), Nolty, Anne⁴ (AUTHOR), Yu, J⁵ (AUTHOR), Mack, Wendy J⁶ (AUTHOR), Chui, Helena C⁷ (AUTHOR), Minazad, Yafa⁸ (AUTHOR), Kloner, Robert A¹ (AUTHOR), Arakaki, Xianghong¹ (AUTHOR)

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association. Dec2024 Supplement 2, Vol. 20 Issue S2, p1-3. 3p.

Higher amyloid burden is associated with faster reduction in cerebral blood flow: a longitudinal study.

Authors: Zhao, Tianrui¹ (AUTHOR) tianruizhao2027@u.northwestern.edu, Tang, Jianing¹ (AUTHOR), Terner, Jamie² (AUTHOR), Joe, Elizabeth B³ (AUTHOR), Braskie, Meredith N⁴ (AUTHOR), Chui, Helena C³ (AUTHOR), Marmarelis, Vasilis⁵ (AUTHOR), Yan, Lirong^1,2 (AUTHOR)

Source: Alzheimer's & Dementia: The Journal of the Alzheimer's Association. Dec2024 Supplement 1, Vol. 20, p1-3. 3p.

Transethnic genome-wide scan identifies novel Alzheimer's disease loci

Authors: Adams, Perrie M., Albert, Marilyn S., Albin, Roger L., Apostolova, Liana G., Arnold, Steven E., Asthana, Sanjay, Atwood, Craig S., Barmada, Michjael M., Barnes, Lisa L., Beach, Thomas G., Becker, James T., Bigio, Eileen H., Bird, Thomas D., Blacker, Deborah, Boeve, Bradley F., Bowen, James D., Boxer, Adam, Burke, James R., Cairns, Nigel J., Cao, Chuanhai, Carlson, Chris S., Carlsson, Cynthia M., Carney, Regina M., Carrasquillo, Minerva M., Carroll, Steven L., Chui, Helena C., Clark, David G., Corneveaux, Jason, Cribbs, David H., Crocco, Elizabeth A., Cruchaga, Carlos, De Jager, Philip L., DeCarli, Charles, DeKosky, Steven T., Demirci, F. Yesim, Dick, Malcolm, Dickson, Dennis W., Doody, Rachelle S., Duara, Ranjan, Ertekin-Taner, Nilufer, Faber, Kelley M., Fairchild, Thomas J., Fallon, Kenneth B., Farlow, Martin R., Ferris, Steven, Frosch, Matthew P., Galasko, Douglas R., Gearing, Marla, Geschwind, Daniel H., Ghetti, Bernardino, Gilbert, John R., Glass, Jonathan D., Graff-Radford, Neill R., Green, Robert C., Growdon, John H., Hakonarson, Hakon, Hamilton, Ronald L., Hardy, John, Harrell, Lindy E., Head, Elizabeth, Honig, Lawrence S., Huebinger, Ryan M., Huentelman, Matthew J., Hulette, Christine M., Hyman, Bradley T., Jarvik, Gail P., Jicha, Gregory A., Jin, Lee-Way, Karydas, Anna, Kauwe, John S.K., Kaye, Jeffrey A., Kim, Ronald, Koo, Edward H., Kowall, Neil W., Kramer, Joel H., LaFerla, Frank M., Lah, James J., Leverenz, James B., Levey, Allan I., Li, Ge, Lieberman, Andrew P., Lin, Chiao-Feng, Lopez, Oscar L., Lyketsos, Constantine G., Mack, Wendy J., Marson, Daniel C., Martiniuk, Frank, Mash, Deborah C., Masliah, Eliezer, McCormick, Wayne C., McCurry, Susan M., McDavid, Andrew N., McKee, Ann C., Mesulam, Marsel, Miller, Bruce L., Miller, Carol A., Miller, Joshua W., Morris, John C., Mukherjee, Shubhabrata, Murrell, Jill R., Myers, Amanda J., O'Bryant, Sid, Olichney, John M., Pankratz, Vernon S., Parisi, Joseph E., Partch, Amanda, Paulson, Henry L., Perry, William, Peskind, Elaine, Petersen, Ronald C., Pierce, Aimee, Poon, Wayne W., Potter, Huntington, Quinn, Joseph F., Raj, Ashok, Raskind, Murray, Reisberg, Barry, Reisch, Joan S., Reitz, Christiane, Ringman, John M., Roberson, Erik D., Rogaeva, Ekaterina, Rosen, Howard J., Rosenberg, Roger N., Royall, Donald R., Sager, Mark A., Sano, Mary, Saykin, Andrew J., Schneider, Julie A., Schneider, Lon S., Seeley, William W., Smith, Amanda G., Sonnen, Joshua A., Spina, Salvatore, Stern, Robert A., Tanzi, Rudolph E., Thornton-Wells, Tricia A., Trojanowski, John Q., Troncoso, Juan C., Tsuang, Debby W., Van Deerlin, Vivianna M., Van Eldik, Linda J., Vardarajan, Badri N., Vinters, Harry V., Vonsattel, Jean Paul, Weintraub, Sandra, Welsh-Bohmer, Kathleen A., Williamson, Jennifer, Wishnek, Sarah, Woltjer, Randall L., Wright, Clinton B., Wu, Chuang-Kuo, Yu, Chang-En, Yu, Lei, Zhang, Xiaoling, Jun, Gyungah R., Chung, Jaeyoon, Mez, Jesse, Barber, Robert, Beecham, Gary W., Bennett, David A., Buxbaum, Joseph D., Byrd, Goldie S., Crane, Paul K., De Jager, Philip, Evans, Denis, Fallin, M. Danielle, Foroud, Tatiana M., Friedland, Robert P., Goate, Alison M., Hendrie, Hugh, Hall, Kathleen S., Hamilton-Nelson, Kara L., Inzelberg, Rivka, Kamboh, M. Ilyas, Kukull, Walter A., Kunkle, Brian W., Kuwano, Ryozo, Larson, Eric B., Logue, Mark W., Manly, Jennifer J., Martin, Eden R., Montine, Thomas J., Naj, Adam, Reiman, Eric M., Sherva, Richard, St. George-Hyslop, Peter H., Thornton, Timothy, Younkin, Steven G., Wang, Li-San, Wendlund, Jens R., Winslow, Ashley R., Haines, Jonathan, Mayeux, Richard, Pericak-Vance, Margaret A., Schellenberg, Gerard, Lunetta, Kathryn L., Farrer, Lindsay A.

Source: In Alzheimer's & Dementia: The Journal of the Alzheimer's Association July 2017 13(7):727-738

Assessment of arterial pulsatility of cerebral perforating arteries using 7T high‐resolution dual‐VENC phase‐contrast MRI.

Authors: Tang, Jianing, Heidari Pahlavian, Soroush, Joe, Elizabeth, Gamez, Maria Tereza, Zhao, Tianrui, Ma, Samantha J., Jin, Jin, Cen, Steven Yong, Chui, Helena C., Yan, Lirong

Source: Magnetic Resonance in Medicine; Aug2024, Vol. 92 Issue 2, p605-617, 13p

Subject Terms: CEREBRAL arteries, CEREBRAL small vessel diseases, YOUNG adults, MAGNETIC resonance imaging

Adherence to a MIND-Like Dietary Pattern, Long-Term Exposure to Fine Particulate Matter Air Pollution, and MRI-Based Measures of Brain Volume: The Women's Health Initiative Memory Study-MRI.

Authors: Cheng Chen^1,2, Hayden, Kathleen M.³, Kaufman, Joel D.^4,5,6, Espeland, Mark A.⁷, Whitsel, Eric A.⁸, Serre, Marc L.⁹, Vizuete, William⁹, Orchard, Tonya S.¹⁰, Xinhui Wang¹¹, Chui, Helena C.¹¹, D'Alton, Mary E.¹, Jiu-Chiuan Chen^11,12 kk3399@columbia.edu, Ka Kahe^1,2

Source: Environmental Health Perspectives. Dec2021, Vol. 129 Issue 12, p127008-1-127008-12. 12p. 5 Charts.

Subject Terms: *Particulate matter, *Air pollution, Brain, Food habits, Mediterranean diet, Confidence intervals, Vegetables, Meat, Multivariate analysis, Magnetic resonance imaging, Regression analysis, Race, Food preferences, Dairy products, DASH diet, Questionnaires, Descriptive statistics, Berries, Ethnic groups, Body mass index, Women's health, Neurodegeneration

Geographic Terms: United States

Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD.

Authors: Wang, Shaowei, Li, Boyang, Li, Jie, Cai, Zhiheng, Hugo, Cristelle, Sun, Yi, Qian, Lu, TCW, Julia, Chui, Helena C., Dikeman, Dante, Asante, Isaac, Louie, Stan G., Bennett, David A., Arvanitakis, Zoe, Remaley, Alan T., Kerman, Bilal E., Yassine, Hussein N.

Source: Molecular Neurodegeneration; 2/4/2024, Vol. 20 Issue 1, p1-26, 26p

Subject Terms: CELLULAR aging, LIFE sciences, MEDICAL sciences, CYTOLOGY, PLURIPOTENT stem cells, ATP-binding cassette transporters