Enhancing oncolytic virotherapy by extracellular vesicle mediated microRNA reprograming of the tumour microenvironment

Authors: Victoria A. Jennings, Reah Rumbold-Hall, Gemma Migneco, Tyler Barr, Katrina Reilly, Nicola Ingram, Isabelle St Hilare, Samuel Heaton, Noura Alzamel, David Jackson, Christy Ralph, Susan Banerjee, Iain McNeish, John C. Bell, Alan A. Melcher, Carolina Ilkow, Graham P. Cook, Fiona Errington-Mais

Source: Frontiers in Immunology, Vol 15 (2024)

Subject Terms: oncolytic virus, miRNA, tumour associated macrophage, tumour microenvironment, anti-tumour immunity, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2024.1500570/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/3783c6665e834788872d5c5ea82da1f8

Temporary treatment cessation compared with continuation of tyrosine kinase inhibitors for adults with renal cancer: the STAR non-inferiority RCT

Authors: Fiona Collinson, Kara-Louise Royle, Jayne Swain, Christy Ralph, Anthony Maraveyas, Tim Eisen, Paul Nathan, Robert Jones, David Meads, Tze Min Wah, Adam Martin, Janine Bestall, Christian Kelly-Morland, Christopher Linsley, Jamie Oughton, Kevin Chan, Elisavet Theodoulou, Gustavo Arias-Pinilla, Amy Kwan, Luis Daverede, Catherine Handforth, Sebastian Trainor, Abdulazeez Salawu, Christopher McCabe, Vicky Goh, David Buckley, Jenny Hewison, Walter Gregory, Peter Selby, Julia Brown, Janet Brown

Source: Health Technology Assessment, Vol 28, Iss 45 (2024)

Subject Terms: clinical trials, randomised, non-inferiority trial, drug administration schedule, carcinoma, renal cell, quality-adjusted life-years, survival, cost–benefit analysis, sunitinib, pazopanib, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/f262d31cdee84d25b7afd7439e0362e7

Efficacy of coxsackievirus A21 against drug-resistant neoplastic B cells

Authors: Matthew Holmes, Gina B. Scott, Samuel Heaton, Tyler Barr, Basem Askar, Louise M.E. Müller, Victoria A. Jennings, Christy Ralph, Cathy Burton, Alan Melcher, Peter Hillmen, Christopher Parrish, Fiona Errington-Mais

Source: Molecular Therapy: Oncolytics, Vol 29, Iss , Pp 17-29 (2023)

Subject Terms: B cell neoplasm, drug resistance, oncolytic virus, coxsackievirus A21, tumor microenvironment, Chronic Lymphocytic Leukemia, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2372770523000244; https://doaj.org/toc/2372-7705

Access URL: https://doaj.org/article/5203c050e9894f55a9405ad6fce9ab42

Phase 1, open-label, dose-escalation study on the safety, pharmacokinetics, and preliminary efficacy of intravenous Coxsackievirus A21 (V937), with or without pembrolizumab, in patients with advanced solid tumors

Authors: Christy Ralph, Sumati Gupta, Matthew Zibelman, Brendan D Curti, Kevin J Harrington, Steven J O'Day, Andrew G Hill, David C Campbell, Gavin M Wright, David E Gerber, Jonathan E Rosenberg, Jaime R Merchan, Charles M Rudin, Hardev S Pandha, Wallace L Akerley, Daphne Day, Timothy D Clay, Ross R Jennens, Yixin Ren, Emmett V Schmidt, Lisa Guttman

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 1 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/11/1/e005007.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/07dff5f507bc4d64bce5f819f24c264d

Iatrogenic ureteric stricture post image guided renal cryoablation in a patient with von hippel-lindau syndrome

Authors: Helen Ng, Vinson Wai-Shun Chan, Jon Cartledge, MB BCh MD FRCSEd(Urol), Michael Kimuli, MB BCh FRCS, Christy Ralph, PhD BMBS BMedSci MA MRCP, Satinder Jagdev, MBChB PhD, Naveen Vasudev, PhD MRCP MBChB BMSc (Hons), Selina Bhattarai, MBBS, MD Pathology, FRCPath, James Lenton, MBChB FRCR, Jonathan Smith, MBChB FRCR, Tze Min Wah, PhD, MBChB, FRCR

Source: Radiology Case Reports, Vol 16, Iss 8, Pp 1980-1984 (2021)

Subject Terms: Ureteric stricture, Cryoablation, Renal cell carcinoma, Von-Hippel Lindau, Complication, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1930043321002922; https://doaj.org/toc/1930-0433

Access URL: https://doaj.org/article/c8d39978b65d40f4bdd816244f935e4f

Urinothorax following percutaneous image-guided renal cryoablation

Authors: Helen Ng, MBChB, Kaiwen Wang, MBChB, Jon Cartledge, MBChB, MD, FRCSEd (Urol), Chandra Shekhar Biyani, MBChB, FRCS, Christy Ralph, PhD, BMBS, BMedSci, MA, MRCP, Satinder Jagdev, MBChB, PhD, Naveen Vasudev, PhD, MRCP, MBChB, BMSc (Hons), Selina Bhattarai, MBBS, MD Pathology, FRCPath, Bobby, Bhartia, MBChB, FRCR, James Lenton, MBChB, FRCR, Jonathan Smith, MBChB, FRCR, Simon Whiteley, MBBS, FRCA, FFICM, Peter Tcherveniakov, MBChB, FRCS, Tze Min Wah, PhD, MBChB, FRCR

Source: Radiology Case Reports, Vol 15, Iss 11, Pp 2348-2352 (2020)

Subject Terms: Urinothorax, Cryoablation, Renal cell carcinoma, Solitary kidney, Complication, Medical physics. Medical radiology. Nuclear medicine, R895-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1930043320304805; https://doaj.org/toc/1930-0433

Access URL: https://doaj.org/article/3a4ab27228674f0f9e70fa9d207167f2

Plasmacytoid dendritic cells orchestrate innate and adaptive anti-tumor immunity induced by oncolytic coxsackievirus A21

Authors: Louise M. E. Müller, Matthew Holmes, Joanne L. Michael, Gina B. Scott, Emma J. West, Karen J. Scott, Christopher Parrish, Kathryn Hall, Sina Stäble, Victoria A. Jennings, Matthew Cullen, Stewart McConnell, Catherine Langton, Emma L. Tidswell, Darren Shafren, Adel Samson, Kevin J. Harrington, Hardev Pandha, Christy Ralph, Richard J. Kelly, Gordon Cook, Alan A. Melcher, Fiona Errington-Mais

Source: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)

Subject Terms: Oncolytic viruses, Coxsackievirus A21, Plasmacytoid DC, Innate immunity, Adaptive immunity, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40425-019-0632-y; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/45333d28906e4c79a697ecb02c401857

Reovirus-induced cell-mediated immunity for the treatment of multiple myeloma within the resistant bone marrow niche

Authors: Victoria Jennings, Christopher Parrish, Christy Ralph, Alan Melcher, Adel Samson, Gordon Cook, Fiona Errington-Mais, Matt Coffey, Munitta Muthana, Gemma Migneco, Louise M E Müller, Gina B Scott, Jenny Down, Sancha King, Basem Askar, Babatunde Oyajobi, Karen Scott, Emma West, Elizabeth J Ilett, Michelle Lawson

Source: Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/9/3/e001803.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/db50054d7a414d2980de99757b9e839e

Current Treatment and Outcomes Benchmark for Locally Advanced or Metastatic Urothelial Cancer From a Large UK-Based Single Centre

Authors: Sue Cheeseman, Matthew Thompson, Will Sopwith, Paul Godden, Divyagiri Seshagiri, Lola Adedokun, Kieran Zucker, Sunjay Jain, Sanjeev Kotwal, Stephen Prescott, Ann Henry, Joji Joseph, Sameer Chilka, Jo-An Roulson, Michael Weston, Simon Burbidge, Simon Brown, Satinder Jagdev, Christy Ralph, Geoff Hall, Naveen S. Vasudev

Source: Frontiers in Oncology, Vol 10 (2020)

Subject Terms: carboplatin, cisplatin, real-world, chemotherapy, urothelial cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2020.00167/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/0dc704cd57da464ba6d11afa599bce2e

Feasibility Study on Using Dynamic Contrast Enhanced MRI to Assess the Effect of Tyrosine Kinase Inhibitor Therapy within the STAR Trial of Metastatic Renal Cell Cancer

Authors: Jim Zhong, Ebrahim Palkhi, David L. Buckley, Fiona J. Collinson, Christy Ralph, Satinder Jagdev, Naveen S. Vasudev, Jayne Swain, Janet E. Brown, Tze Min Wah

Source: Diagnostics, Vol 11, Iss 7, p 1302 (2021)

Subject Terms: dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), tyrosine kinase inhibitor, anti-angiogenic therapy, metastatic renal cell cancer, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4418/11/7/1302; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/4d6d2aafbb954842b324eda9760a2653

Evidence for Oncolytic Virotherapy: Where Have We Got to and Where Are We Going?

Authors: Samantha Turnbull, Emma J. West, Karen J. Scott, Elizabeth Appleton, Alan Melcher, Christy Ralph

Source: Viruses, Vol 7, Iss 12, Pp 6291-6312 (2015)

Subject Terms: oncolytic virus, immunotherapy, reovirus, vaccinia, HSV, clinical trials, Microbiology, QR1-502

File Description: electronic resource

Relation: http://www.mdpi.com/1999-4915/7/12/2938; https://doaj.org/toc/1999-4915

Access URL: https://doaj.org/article/3696656bf094438d87d6887fd4f64d83

Essential Forms of Capital for Sustainable Community Development

Authors: Rainey, Daniel V., Robinson, Kenneth L., Allen, Ivye, Christy, Ralph D.

Source: American Journal of Agricultural Economics, 2003 Aug 01. 85(3), 708-715.

Access URL: https://www.jstor.org/stable/1244999

Linking Globalization, Economic Growth and Poverty: Impacts of Agribusiness Strategies on Sub-Saharan Africa

Authors: Weatherspoon, Dave, Cacho, Joyce, Christy, Ralph

Source: American Journal of Agricultural Economics, 2001 Aug 01. 83(3), 722-729.

Access URL: https://www.jstor.org/stable/1245106

Markets or Government? Balancing Imperfect and Complementary Alternatives

Authors: Christy, Ralph D.

Source: American Journal of Agricultural Economics, 1996 Dec 01. 78(5), 1145-1156.

Access URL: https://www.jstor.org/stable/1243485

The Impacts of Structural Change and Public Policy on the Rural Disadvantaged

Authors: Christy, Ralph D., Figueroa, Enrique E.

Source: American Journal of Agricultural Economics, 1990 Dec 01. 72(5), 1169-1178.

Access URL: https://www.jstor.org/stable/1242527

Limited Resource Farmers and the Marketing System

Authors: Dagher, Magid A., Christy, Ralph D., McLean-Meyinsse, Patricia E.

Source: American Journal of Agricultural Economics, 1991 Dec 01. 73(5), 1485-1489.

Access URL: https://www.jstor.org/stable/1242408

African Americans in Rural Society: Needed Directions in Public Policy

Authors: Allen, Joyce E., Christy, Ralph D.

Source: American Journal of Agricultural Economics, 1992 Aug 01. 74(3), 826-833.

Access URL: https://www.jstor.org/stable/1242604

Innovative institutions, public policies and private strategies for agro-enterprise development

Authors: Innovative institutions, public policies, and private strategies for inclusive agro-enterprise development (Symposium) (2012 : Foz do Iguaçu, Brazil), Tihanyi, Krisztina, 1973, Mabaya, Edward, Mhlanga, Nomathemba, Da Silva, Carlos A., Christy, Ralph D., Food and Agriculture Organization of the United Nations

Access URL: http://hdl.handle.net/2027/umn.31951d03818924n

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Private strategies and public policies : the economics of information and the economic organization of markets

Authors: Christy, Ralph D., New York State College of Agriculture and Life Sciences. Department of Agricultural, Resource, and Managerial Economics.

Access URL: http://hdl.handle.net/2027/umn.31951d03886038g