A Randomized, Phase III Trial to Evaluate Rucaparib Monotherapy as Maintenance Treatment in Patients With Newly Diagnosed Ovarian Cancer (ATHENA–MONO/GOG-3020/ENGOT-ov45)

Authors: Monk, Bradley J., Parkinson, Christine, Lim, Myong Cheol, O'Malley, David M., Oaknin, Ana, Wilson, Michelle K., Coleman, Robert L., Lorusso, Domenica, Bessette, Paul, Ghamande, Sharad, Christopoulou, Athina, Provencher, Diane, Prendergast, Emily, Demirkiran, Fuat, Mikheeva, Olga, Yeku, Oladapo, Chudecka-Glaz, Anita, Schenker, Michael, Littell, Ramey D., Safra, Tamar, Chou, Hung-Hsueh, Morgan, Mark A., Drochýtek, Vít, Barlin, Joyce N., Van Gorp, Toon, Ueland, Fred, Lindahl, Gabriel, Anderson, Charles, Collins, Dearbhaile C., Moore, Kathleen, Marme, Frederik, Westin, Shannon N., McNeish, Iain A., Shih, Danny, Lin, Kevin K., Goble, Sandra, Hume, Stephanie, Fujiwara, Keiichi, Kristeleit, Rebecca S.

Source: Journal of clinical oncology. 40(34):3952-3964

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173119109.0x000001&indx=1&recIds=ETOCvdc_100173119109.0x000001

Real-world effectiveness and safety of first-line (1L) avelumab + axitinib in patients with advanced renal cell carcinoma (aRCC): Primary analysis of the AVION study.

Authors: Merseburger, Axel Stuart, Baklanova, Olga, Garlonta, Victor T., Androulakis, Nikolaos E. M., Christopoulou, Athina, Timotheadou, Eleni, Demey, Wim, Janssen, Jan, Ivanyi, Philipp, Brouwers, Barbara Anna Henk, Wynendaele, Wim, Wang, Lusha, Kostkova, Lenka, Hoffman, Jason, Manzel, Arndt, Koumarianou, Anna

Source: Journal of Clinical Oncology; 2/20/2025 Supplement 5, Vol. 43, p474-474, 177p

Steroid Use Independently Predicts for Poor Outcomes in Patients With Advanced NSCLC and High PD-L1 Expression Receiving First-Line Pembrolizumab Monotherapy

Authors: Mountzios, Giannis, de Toma, Alessandro, Economopoulou, Panagiota, Friedlaender, Alex, Banini, Marco, Lo Russo, Giuseppe, Baxevanos, Panagiotis, Roila, Fausto, Banna, Giuseppe Luigi, Christopoulou, Athina, Jimenez, Beatriz, Collazo-Lorduy, Ana, Linardou, Helena, Calles, Antonio, Galetta, Domenico, Addeo, Alfredo, Camerini, Andrea, Pizzutilo, Pamela, Kosmidis, Paris, Garassino, Marina Chiara, Proto, Claudia, Signorelli, Diego, Metro, Giulio

Source: In Clinical Lung Cancer March 2021 22(2):e180-e192

Implementing geriatric assessment for dose optimization of CDK4/6 inhibitors in older breast cancer patients.

Authors: Valachis, Antonis, Biganzoli, Laura, Christopoulou, Athina, Fjermeros, Kamilla, Fountzila, Elena, Geisler, Jürgen, Gomez-Bravo, Raquel, Karihtala, Peeter, Kosmidis, Paris, Koutras, Angelos, Linardou, Helena, Lindman, Henrik, Martínez-Ballestero, Iván, Rodríguez, Anna Belén, Meattini, Icro, Munoz-Mateu, Montserrat, Othman, Mukhrizah, Psyrri, Amanda, Risi, Emanuela, Schiza, Aglaia

Source: Future Oncology; 2024, Vol. 20 Issue 37, p2937-2948, 12p

Molecular Alterations in Paired Epithelial Ovarian Tumors in Patients Treated with Neoadjuvant Chemotherapy.

Authors: Nikolaidi, Adamantia, Papadopoulou, Eirini, Haidopoulos, Dimitrios, Liontos, Michalis, Fountzilas, Elena, Tsaousis, Georgios, Goula, Kalliroi, Tsolaki, Eleftheria, Christopoulou, Athina, Binas, Ioannis, Stamatopoulou, Sofia, Koumarianou, Anna, Karageorgopoulou, Sofia, Goussia, Anna, Psyrri, Amanda, Papadimitriou, Christos, Gogas, Helen

Source: Cancers; Nov2024, Vol. 16 Issue 21, p3580, 13p

Subject Terms: THERAPEUTIC use of antineoplastic agents, STATISTICAL correlation, RESEARCH funding, ENZYME inhibitors, CYTOREDUCTIVE surgery, CANCER patients, RETROSPECTIVE studies, LYMPHOCYTES, DESCRIPTIVE statistics, CANCER chemotherapy, ADJUVANT chemotherapy, CELL lines, COMBINED modality therapy, GENE expression profiling, RESEARCH, OVARIAN epithelial cancer, GENETIC mutation, PACLITAXEL, COMPARATIVE studies, MOLECULAR pathology, PLATINUM, SEQUENCE analysis

Real-world clinical outcome and toxicity data and economic aspects in patients with advanced breast cancer treated with cyclin-dependent kinase 4/6 (CDK4/6) inhibitors combined with endocrine therapy: the experience of the Hellenic Cooperative Oncology Group

Authors: Fountzilas, Elena, Koliou, Georgia-Angeliki, Vozikis, Athanassios, Rapti, Vassiliki, Nikolakopoulos, Achilleas, Boutis, Anastasios, Christopoulou, Athina, Kontogiorgos, Ioannis, Karageorgopoulou, Sofia, Lalla, Efthalia, Tryfonopoulos, Dimitrios, Boukovinas, Ioannis, Rapti, Cleopatra, Nikolaidi, Adamantia, Karteri, Sofia, Moirogiorgou, Evangelia, Binas, Ioannis, Mauri, Davide, Aravantinos, Gerasimos, Zagouri, Flora, Saridaki, Zacharenia, Psyrri, Amanda, Bafaloukos, Dimitrios, Koumarianou, Anna, Res, Eleni, Linardou, Helena, Mountzios, Giannis, Razis, Evangelia, Fountzilas, George, Koumakis, Georgios

Source: In ESMO Open 2020 5(4)

Impact of performance status on non-small-cell lung cancer patients with a PD-L1 tumour proportion score ≥50% treated with front-line pembrolizumab

Authors: Friedlaender, Alex, Metro, Giulio, Signorelli, Diego, Gili, Alessio, Economopoulou, Panagiota, Roila, Fausto, Banna, Giuseppe, De Toma, Alessandro, Camerini, Andrea, Christopoulou, Athina, Lo Russo, Giuseppe, Banini, Marco, Galetta, Domenico, Jimenez, Beatriz, Collazo-Lorduy, Ana, Calles, Antonio, Baxevanos, Panagiotis, Linardou, Helena, Kosmidis, Paris, Mountzios, Giannis, Garassino, Marina C., Addeo, Alfredo

Source: Acta oncologica. 59(9):1058-1063

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100115554508.0x000001&indx=1&recIds=ETOCvdc_100115554508.0x000001

Polygenic Risk Score (PRS) Combined with NGS Panel Testing Increases Accuracy in Hereditary Breast Cancer Risk Estimation.

Authors: Tsoulos, Nikolaos, Papadopoulou, Eirini, Agiannitopoulos, Konstantinos, Grigoriadis, Dimitrios, Tsaousis, Georgios N., Bouzarelou, Dimitra, Gogas, Helen, Troupis, Theodore, Venizelos, Vassileios, Fountzilas, Elena, Theochari, Maria, Ziogas, Dimitrios C., Giassas, Stylianos, Koumarianou, Anna, Christopoulou, Athina, Busby, George, Nasioulas, George, Markopoulos, Christos

Source: Diagnostics (2075-4418); Aug2024, Vol. 14 Issue 16, p1826, 12p

Subject Terms: GENETIC risk score, ETIOLOGY of diseases, FAMILY history (Medicine), DISEASE risk factors, GENETIC variation

Comprehensive Analysis of CXCR4, JUNB, and PD-L1 Expression in Circulating Tumor Cells (CTCs) from Prostate Cancer Patients.

Authors: Roumeliotou, Argyro, Strati, Areti, Chamchougia, Foteini, Xagara, Anastasia, Tserpeli, Victoria, Smilkou, Stavroula, Lagopodi, Elina, Christopoulou, Athina, Kontopodis, Emmanouil, Drositis, Ioannis, Androulakis, Nikolaos, Georgoulias, Vassilis, Koinis, Filippos, Kotsakis, Athanasios, Lianidou, Evi, Kallergi, Galatea

Source: Cells (2073-4409); May2024, Vol. 13 Issue 9, p782, 19p

Subject Terms: PROSTATE cancer patients, CXCR4 receptors, PROGRAMMED death-ligand 1, OVERALL survival, BIOMARKERS

Cytoreductive Surgery Plus Hyperthermic Intraperitoneal Chemotherapy for Patients with Peritoneal Metastases from Endometrial Cancer

Authors: Cornali, Tommaso, Sammartino, Paolo, Kopanakis, Nikolaos, Christopoulou, Athina, Framarino dei Malatesta, Marialuisa, Efstathiou, Elias, Spagnoli, Alessandra, Ciardi, Antonio, Biacchi, Daniele, Spiliotis, John

Source: Annals of surgical oncology. 25(3):679-687

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100118560570.0x000001&indx=1&recIds=ETOCvdc_100118560570.0x000001

Functional Analysis of Viable Circulating Tumor Cells from Triple-Negative Breast Cancer Patients Using TetherChip Technology.

Authors: Vardas, Vasileios, Ju, Julia A., Christopoulou, Athina, Xagara, Anastasia, Georgoulias, Vassilis, Kotsakis, Athanasios, Alix-Panabières, Catherine, Martin, Stuart S., Kallergi, Galatea

Source: Cells (2073-4409); Aug2023, Vol. 12 Issue 15, p1940, 19p

Subject Terms: TRIPLE-negative breast cancer, FUNCTIONAL analysis, CANCER patients, BREAST, DRUG efficacy, BREAST cancer

Immune Checkpoint and EMT-Related Molecules in Circulating Tumor Cells (CTCs) from Triple Negative Breast Cancer Patients and Their Clinical Impact.

Authors: Vardas, Vasileios, Tolios, Anastasios, Christopoulou, Athina, Georgoulias, Vassilis, Xagara, Anastasia, Koinis, Filippos, Kotsakis, Athanasios, Kallergi, Galatea

Source: Cancers; Apr2023, Vol. 15 Issue 7, p1974, 15p

Subject Terms: STATISTICS, EXPERIMENTAL design, PROGRAMMED death-ligand 1, IMMUNE checkpoint proteins, FLUOROIMMUNOASSAY, GENE expression, TREATMENT effectiveness, SEVERITY of illness index, DESCRIPTIVE statistics, RESEARCH funding, DATA analysis, BREAST tumors, OVERALL survival, PHENOTYPES

Phenotypic Characterization of Circulating Tumor Cells Isolated from Non-Small and Small Cell Lung Cancer Patients.

Authors: Roumeliotou, Argyro, Pantazaka, Evangelia, Xagara, Anastasia, Dimitrakopoulos, Foteinos-Ioannis, Koutras, Angelos, Christopoulou, Athina, Kourelis, Theodoros, Aljarba, Nada H., Alkahtani, Saad, Koinis, Filippos, Kotsakis, Athanasios, Kallergi, Galatea

Source: Cancers; Jan2023, Vol. 15 Issue 1, p171, 16p

Subject Terms: LUNG cancer prognosis, SMALL cell carcinoma, MICROSCOPY, METASTASIS, CANCER patients, GENE expression, TUMOR classification, RESEARCH funding, TUMOR markers, TRANSCRIPTION factors, PROGRESSION-free survival, PHENOTYPES, OVERALL survival, PROPORTIONAL hazards models

Predictive and prognostic significance of PIOS (Patras Immunotherapy Score) model in patients with advanced NSCLC treated with nivolumab or pembrolizumab: Results from a validation cohort.

Authors: Dimtrakopoulos, Foteinos-Ioannis D., Mountzios, Giannis Socrates, Christopoulos, Petros, Papastergiou, Thomas, Zervas, Eleftherios, Agelaki, Sofia, Samantas, Epaminondas, Athanasiadis, Ilias, Baka, Sofia, Syrigos, Kostas N., Christopoulou, Athina, Lianos, Evangelos, Tsoukalas, Nikolaos, Perdikouri, Eleni Isidora, Oikonomopoulos, Georgios, Kalofonou, Foteini, Makatsoris, Thomas, Koutras, Angelos, Megalooikonomou, Vasileios, Kalofonos, Haralabos

Source: Journal of clinical oncology. 39(15 suppl):e21164-e21164

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173222367.0x000001&indx=1&recIds=ETOCvdc_100173222367.0x000001

Thromboprophylaxis in active cancer patients: Is it a controversial clinical issue or not? Preliminary results of ACT4CAT study.

Authors: Tsoukalas, Nikolaos, Christopoulou, Athina, Papandreou, Christos N., Koumarianou, Anna, Athanasiadis, Ilias, Peroukidis, Stavros, Samelis, Georgios, Psyrri, Amanda, Kapodistrias, Nikolaos, Nikolakopoulos, Achilleas, Andreadis, Charalampos, Ardavanis, Alexandros, Samantas, Epaminondas, Bokas, Alexandros, Vassilios, Barbounis, Kentepozidis, Nikolaos K., Mavroudis, Dimitrios, Athanasiadis, Athanasios, Papakotoulas, Pavlos, Boukovinas, Ioannis

Source: Journal of clinical oncology. 39(15 suppl):e18803-e18803

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173214254.0x000001&indx=1&recIds=ETOCvdc_100173214254.0x000001

Validation of Patras Immunotherapy Score model for prediction and prognosis of patients with advanced NSCLC treated with nivolumab or pembrolizumab: results from a European multicentre study.

Authors: Dimitrakopoulos, Foteinos-Ioannis, Mountzios, Giannis, Christopoulos, Petros, Papastergiou, Thomas, Elshiaty, Mariam, Daniello, Lea, Zervas, Elefterios, Agelaki, Sofia, Samantas, Epaminondas, Nikolaidi, Adamantia, Athanasiadis, Ilias, Baka, Sofia, Syrigos, Konstantinos, Christopoulou, Athina, Lianos, Evangelos, Samitas, Konstantinos, Tsoukalas, Nikolaos, Perdikouri, Eleni-Isidora, Oikonomopoulos, George, Kottorou, Anastasia

Source: Therapeutic Advances in Medical Oncology; 9/8/2022, p1-16, 16p

PARP-1 Expression and BRCA1 Mutations in Breast Cancer Patients' CTCs.

Authors: Sklias, Thodoris, Vardas, Vasileios, Pantazaka, Evangelia, Christopoulou, Athina, Georgoulias, Vassilis, Kotsakis, Athanasios, Vasilopoulos, Yiannis, Kallergi, Galatea

Source: Cancers; Apr2022, Vol. 14 Issue 7, p1731, 13p

Subject Terms: SEQUENCE analysis, GENETIC mutation, BRCA genes, LOG-rank test, GENE expression, CANCER patients, TRANSFERASES, GENOTYPES, EXTRACELLULAR space, BREAST tumors, NUCLEIC acids

Ablative Radioembolization (SIRT) of a Large Inoperable Renal Cell Carcinoma Invading the Liver That Resulted in Hematuria Control and Complete Necrosis by mRECIST Criteria.

Authors: Spyridonidis, Ioannis, Dimopoulos, Platon, Spyridonidis, Trifon, Christopoulou, Athina, Katsanos, Konstantinos

Source: Clinical Nuclear Medicine; Jun2024, Vol. 49 Issue 6, p557-558, 2p

Front-Line Bevacizumab plus Chemotherapy with or without Maintenance Therapy for Metastatic Breast Cancer: An Observational Study by the Hellenic Oncology Research Group.

Authors: Kokkali, Stefania, Saloustros, Emmanouil, Stefanou, Dimitra, Makrantonakis, Paris, Kentepozidis, Nikolaos, Boukovinas, Ioannis, Xenidis, Nikolaos, Katsaounis, Panagiotis, Ardavanis, Alexandros, Ziras, Nikolaos, Christopoulou, Athina, Rigas, George, Kalbakis, Kostas, Vardakis, Nikolaos, Emmanouilides, Christos, Athanasiadis, Ilias, Anagnostopoulos, Athanassios, Hatzidaki, Dora, Prinarakis, Efthimios, Simopoulou, Foteini

Source: Current Oncology; Feb2022, Vol. 29 Issue 2, p1237-1251, 15p, 6 Charts, 4 Graphs

Subject Terms: BREAST cancer prognosis, FATIGUE risk factors, SCIENTIFIC observation, ACQUISITION of data methodology, CONFIDENCE intervals, CANCER chemotherapy, EPIDERMAL growth factor, METASTASIS, ANTINEOPLASTIC agents, RETROSPECTIVE studies, NEUTROPENIA, SURVIVAL analysis (Biometry), MEDICAL records, ANEMIA, DESCRIPTIVE statistics, BEVACIZUMAB, TERMINATION of treatment, BREAST tumors, DISEASE risk factors

Real-world safety and efficacy data of immunotherapy in patients with cancer and autoimmune disease: the experience of the Hellenic Cooperative Oncology Group.

Authors: Fountzilas, Elena, Lampaki, Sofia, Koliou, Georgia-Angeliki, Koumarianou, Anna, Levva, Sofia, Vagionas, Anastasios, Christopoulou, Athina, Laloysis, Athanasios, Psyrri, Amanda, Binas, Ioannis, Mountzios, Giannis, Kentepozidis, Nikolaos, Kotsakis, Athanassios, Saloustros, Emmanouil, Boutis, Anastasios, Nikolaidi, Adamantia, Fountzilas, George, Georgoulias, Vassilis, Chrysanthidis, Miltiadis, Kotteas, Elias

Source: Cancer Immunology, Immunotherapy; Feb2022, Vol. 71 Issue 2, p327-337, 11p

Subject Terms: CANCER patients, AUTOIMMUNE diseases, DRUG side effects, NON-small-cell lung carcinoma, IMMUNE checkpoint inhibitors