Treatment patterns and outcomes in follicular lymphoma with POD24: an analysis from the LEO Consortium

Authors: Jonathan R. Day, Melissa C. Larson, Urshila Durani, Jean L. Koff, Yucai Wang, Thomas M. Habermann, Izidore S. Lossos, Loretta J. Nastoupil, Christopher Strouse, Dai Chihara, Peter Martin, John P. Leonard, Jonathon B. Cohen, Brad S. Kahl, Jia Ruan, W. Richard Burack, Jonathan W. Friedberg, James R. Cerhan, Christopher R. Flowers, Brian K. Link, Matthew J. Maurer, Carla Casulo

Source: Blood Advances, Vol 9, Iss 5, Pp 1013-1023 (2025)

Subject Terms: Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2473952924006773; https://doaj.org/toc/2473-9529

Access URL: https://doaj.org/article/1b557fc32cda4862a658becc8015d190

Ruxolitinib synergizes with regulatory T cells to improve inflammation but has no added benefits in decreasing albuminuria in SLE

Authors: Mi-Ae Lyu, Ximing Tang, Maria Gabriela Raso, Meixian Huang, Ke Zeng, Tara Sadeghi, Christopher R. Flowers, Simrit Parmar

Source: Frontiers in Immunology, Vol 16 (2025)

Subject Terms: adoptive cell therapy, regulatory T cells (Tregs), allogeneic, umbilical cord blood (UCB), ruxolitinib, JAK/STAT pathway, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2025.1449693/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/b9f5bb5f93e54c6b847f7b2195c8b1e2

Utilization of Real-World Data to Facilitate Clinical Trials for Patients with Lymphoma

Authors: Dai Chihara, Brian P. Hobbs, Matthew J. Maurer, Christopher R. Flowers

Source: Pharmacoepidemiology, Vol 3, Iss 3, Pp 252-264 (2024)

Subject Terms: lymphoma, real-world evidence, clinical trial, data science, Therapeutics. Pharmacology, RM1-950, Other systems of medicine, RZ201-999, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://www.mdpi.com/2813-0618/3/3/17; https://doaj.org/toc/2813-0618

Access URL: https://doaj.org/article/d0b5d43e40cd4e559035c477f665558d

Cord blood T regulatory cells synergize with ruxolitinib to improve GVHD outcomes

Authors: Ke Zeng, Hongbing Ma, Meixian Huang, Mi-Ae Lyu, Tara Sadeghi, Christopher R. Flowers, Simrit Parmar

Source: Frontiers in Transplantation, Vol 3 (2024)

Subject Terms: GVHD, T regulatory cell, allogeneic, cord blood, ruxolitinib, Specialties of internal medicine, RC581-951

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/frtra.2024.1448650/full; https://doaj.org/toc/2813-2440

Access URL: https://doaj.org/article/3938738d4cd34e66a46f8d5c3ab3ddd8

Population pharmacokinetics and exposure–response analyses of polatuzumab vedotin in patients with previously untreated DLBCL from the POLARIX study

Authors: Rong Deng, Leonid Gibiansky, Tong Lu, Christopher R. Flowers, Laurie H. Sehn, Qi Liu, Priya Agarwal, Michael Z. Liao, Randall Dere, Calvin Lee, Gabriel Man, Jamie Hirata, Chunze Li, Dale Miles

Source: CPT: Pharmacometrics & Systems Pharmacology, Vol 13, Iss 6, Pp 1055-1066 (2024)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://doaj.org/toc/2163-8306

Access URL: https://doaj.org/article/94a1657630df4f2992ff53a1a61eb869

CASi: A framework for cross-timepoint analysis of single-cell RNA sequencing data

Authors: Yizhuo Wang, Christopher R. Flowers, Michael Wang, Xuelin Huang, Ziyi Li

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/41fd27dd21554bddb14a9c1ba9e30400

CXCR4-enriched T regulatory cells preferentially home to bone marrow and resolve inflammation

Authors: Meixian Huang, Zeng Ke, Mi-Ae Lyu, Lucia Masarova, Tara Sadeghi, Christopher R. Flowers, Simrit Parmar

Source: iScience, Vol 27, Iss 9, Pp 110830- (2024)

Subject Terms: Immunology, Immunity, Cell biology, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004224020558; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/33d674a18d9d471dbea146cf07d4d88c

Safety and activity of lenalidomide in combination with obinutuzumab in patients with relapsed indolent non-Hodgkin lymphoma: a single group, open-label, phase 1/2 trialResearch in context

Authors: Ashwath Gurumurthi, Collin K. Chin, Lei Feng, Nathan H. Fowler, Paolo Strati, Fredrick B. Hagemeister, Luis E. Fayad, Jason R. Westin, Chizobam Obi, Janine Arafat, Ranjit Nair, Raphael E. Steiner, Sattva S. Neelapu, Christopher R. Flowers, Loretta J. Nastoupil

Source: EClinicalMedicine, Vol 74, Iss , Pp 102747- (2024)

Subject Terms: Follicular lymphoma, Lenalidomide, Obinutuzumab, Relapsed, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589537024003262; https://doaj.org/toc/2589-5370

Access URL: https://doaj.org/article/ce025c6f41e44776b07e12e8ef403353

Integrative analysis of clinicopathological features defines novel prognostic models for mantle cell lymphoma in the immunochemotherapy era: a report from The North American Mantle Cell Lymphoma Consortium

Authors: Julie M. Vose, Kai Fu, Lu Wang, Adnan Mansoor, Douglas Stewart, Hongxia Cheng, Lynette Smith, Ji Yuan, Hina Naushad Qureishi, Brian K. Link, Melissa H. Cessna, Paul M. Barr, Brad S. Kahl, Matthew S. Mckinney, Nadia Khan, Ranjana H. Advani, Peter Martin, Andre H. Goy, Tycel J. Phillips, Amitkumar Mehta, Manali Kamdar, Michael Crump, Barbara Pro, Christopher R. Flowers, Caron A. Jacobson, Sonali M. Smith, Deborah M. Stephens, Veronika Bachanova, Zhaohui Jin, Shishou Wu, Francisco Hernandez-Ilizaliturri, Pallawi Torka, Andrea Anampa-Guzmán, Farshid Kashef, Xing Li, Sunandini Sharma, Timothy C. Greiner, James O. Armitage, Matthew Lunning, Dennis D. Weisenburger, Robert G. Bociek, Javeed Iqbal, Guohua Yu, Chengfeng Bi, the North American Mantle Cell Lymphoma Consortium

Source: Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-12 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-8722

Access URL: https://doaj.org/article/38f17dfbe7af46e394e36a8885eeec63

Immune-depleted tumor microenvironment is associated with poor outcomes and BTK inhibitor resistance in mantle cell lymphoma

Authors: Preetesh Jain, Krystle Nomie, Nikita Kotlov, VitaIy Segodin, Holly Hill, Chi Young Ok, Ahmed Fetooh, Rashmi Kanagal-Shamanna, Francisco Vega, Alexander Bagaev, Nathan Fowler, Christopher R. Flowers, Michael Wang

Source: Blood Cancer Journal, Vol 13, Iss 1, Pp 1-5 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2044-5385

Access URL: https://doaj.org/article/19cd5314563442188352426c12d4f839

PD-L1+ macrophages are associated with favorable features in primary mediastinal (thymic) large B-cell lymphoma

Authors: Raphael E. Steiner, Edwin R. Parra, Francisco Vega, Lei Feng, Jason R. Westin, Sattva S. Neelapu, Paolo Strati, Michael R. Green, Christopher R. Flowers, Luisa M. Solis, Ignacio I. Wistuba, Sairah Ahmed, Ranjit Nair, Fredrick B. Hagemeister, Mansoor Noorani, Mario L. Marques-Piubelli

Source: Experimental Hematology & Oncology, Vol 12, Iss 1, Pp 1-5 (2023)

Subject Terms: Primary mediastinal large B-cell lymphoma, Macrophages, PD-L1, CD30, Biomarker, Diseases of the blood and blood-forming organs, RC633-647.5, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2162-3619

Access URL: https://doaj.org/article/e3114eba62f94495bc871889c61eb0f9

Effect of delayed cell infusion in patients with large B-cell lymphoma treated with chimeric antigen receptor T-cell therapy

Authors: Andrew P. Jallouk, Naishu Kui, Ryan Sun, Jason R. Westin, Raphael E. Steiner, Ranjit Nair, Loretta J. Nastoupil, Luis E. Fayad, Ajlan Al Zaki, Misha Hawkins, Sherry Adkins, Mansoor Noorani, Kaberi Das, Jared Henderson, Elizabeth J. Shpall, Partow Kebriaei, Jeremy Ramdial, Christopher R. Flowers, Sattva S. Neelapu, Sairah Ahmed, Paolo Strati

Source: Haematologica, Vol 109, Iss 5 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/11368; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/b01259b6f4fa46b6872193b9823dd88d

Matching-adjusted indirect comparison from the Lymphoma Epidemiology of Outcomes Consortium for Real World Evidence (LEO CReWE) study to a clinical trial of mosunetuzumab in relapsed or refractory follicular lymphoma

Authors: Matthew J. Maurer, Carla Casulo, Melissa C. Larson, Thomas M. Habermann, Izidore S. Lossos, Yucai Wang, Loretta J. Nastoupil, Christopher Strouse, Dai Chihara, Peter Martin, Jonathon B. Cohen, Brad S. Kahl, W Richard Burack, Jean L. Koff, Yong Mun, Anthony Masaquel, Mei Wu, Michael C. Wei, Ashwini Shewade, Jia Li, James R. Cerhan, Brian K. Link, Christopher R. Flowers

Source: Haematologica, Vol 999, Iss 1 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/11360; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/1d7e46afb331468e9c6f00cad9ff0929

Allogeneic cord blood regulatory T cells decrease dsDNA antibody and improve albuminuria in systemic lupus erythematosus

Authors: Mi-Ae Lyu, Ximing Tang, Joseph D. Khoury, Maria Gabriela Raso, Meixian Huang, Ke Zeng, Mitsutaka Nishimoto, Hongbing Ma, Tara Sadeghi, Christopher R. Flowers, Simrit Parmar

Source: Frontiers in Immunology, Vol 14 (2023)

Subject Terms: umbilical cord blood (UCB), allogeneic, regulatory T cells (Tregs), systemic lupus erythematosus (SLE), lupus nephritis (LN), dsDNA antibodies, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fimmu.2023.1217121/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/9f82fde00d65413a8abc398e3a17fd44

Polatuzumab vedotin plus bendamustine and rituximab or obinutuzumab in relapsed/refractory follicular lymphoma: a phase Ib/II study

Authors: Christopher R. Flowers, Matthew J. Matasar, Alex F. Herrera, Mark Hertzberg, Sarit Assouline, Judit Demeter, Andrew McMillan, Amitkumar Mehta, Stephen Opat, Marek Trnňný, Lisa Musick, Jamie Hirata, Annie Yang, Laurie H. Sehn

Source: Haematologica, Vol 109, Iss 4 (2023)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/11281; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/831f0cfd181940158d1d3914f1090dfd

Cotargeting of BTK and MALT1 overcomes resistance to BTK inhibitors in mantle cell lymphoma

Authors: Vivian Changying Jiang, Yang Liu, Junwei Lian, Shengjian Huang, Alexa Jordan, Qingsong Cai, Ruitao Lin, Fangfang Yan, Joseph McIntosh, Yijing Li, Yuxuan Che, Zhihong Chen, Jovanny Vargas, Maria Badillo, John Nelson Bigcal, Heng-Huan Lee, Wei Wang, Yixin Yao, Lei Nie, Christopher R. Flowers, Michael Wang

Source: The Journal of Clinical Investigation, Vol 133, Iss 3 (2023)

Subject Terms: Hematology, Therapeutics, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/dfe8948e0b6d44bcb2459e48fba2403e

Axicabtagene ciloleucel in relapsed or refractory large B-cell lymphoma patients in complete metabolic response

Authors: Andrew P. Jallouk, Sushanth Gouni, Jason Westin, Lei Feng, Haleigh Mistry, Raphael E. Steiner, Jinsu James, Mansoor Noorani, Sandra Horowitz, Nahum Puebla-Osorio, Luis E. Fayad, Swaminathan P. Iyer, Misha Hawkins, Christopher R. Flowers, Sairah Ahmed, Loretta J. Nastoupil, Partow Kebriaei, Elizabeth J. Shpall, Sattva S. Neelapu, Yago Nieto, Paolo Strati

Source: Haematologica, Vol 108, Iss 4 (2022)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/10866; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/e594de9ca2264723b1d6eb36952f069d

Adjunct Therapy with T Regulatory Cells Decreases Inflammation and Preserves the Anti-Tumor Activity of CAR T Cells

Authors: Ke Zeng, Meixian Huang, Mi-Ae Lyu, Joseph D. Khoury, Sairah Ahmed, Krina K. Patel, Boro Dropulić, Jane Reese-Koc, Paolo F. Caimi, Tara Sadeghi, Marcos de Lima, Christopher R. Flowers, Simrit Parmar

Source: Cells, Vol 12, Iss 14, p 1880 (2023)

Subject Terms: regulatory T cells, CAR T cells, CRS, lymphoma, allogeneic, umbilical cord blood, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/12/14/1880; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/d9710af70c644334bc7a67911e854f02

Herpes simplex virus lymphadenitis is associated with tumor reduction in a patient with chronic lymphocytic leukemia

Authors: Andres Chang, Anton M. Sholukh, Andreas Wieland, David L. Jaye, Mary Carrington, Meei-Li Huang, Hong Xie, Keith R. Jerome, Pavitra Roychoudhury, Alexander L. Greninger, Jean L. Koff, Jonathon B. Cohen, David M. Koelle, Lawrence Corey, Christopher R. Flowers, Rafi Ahmed

Source: The Journal of Clinical Investigation, Vol 132, Iss 18 (2022)

Subject Terms: Hematology, Immunology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/b553259f84e34b31aaacb3c20315e95c

Comparison of Access to Novel Drugs for Lymphoma and Chronic Lymphocytic Leukemia Between India and the United States

Authors: Vishwanath Sathyanarayanan, Christopher R. Flowers, Swaminathan P. Iyer

Source: JCO Global Oncology, Vol , Iss 6, Pp 1124-1133 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2687-8941

Access URL: https://doaj.org/article/cc393339519a45dc9eb5637a36459980