Bacteriocin-like peptides encoded by a horizontally acquired island mediate Neisseria gonorrhoeae autolysis.

Authors: Katy Poncin, Samantha A McKeand, Hayley Lavender, Kacper Kurzyp, Odile B Harrison, Annabell Roberti, Charlotte Melia, Errin Johnson, Martin C J Maiden, David R Greaves, Rachel Exley, Christoph M Tang

Source: PLoS Biology, Vol 23, Iss 2, p e3003001 (2025)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1544-9173; https://doaj.org/toc/1545-7885

Access URL: https://doaj.org/article/56fef2f1fbd04394a1e880feb49626b3

Tackling immunosuppression by Neisseria gonorrhoeae to facilitate vaccine design.

Authors: Rebekah A Jones, Fidel Ramirez-Bencomo, Gail Whiting, Min Fang, Hayley Lavender, Kacper Kurzyp, Angela Thistlethwaite, Lenka Stejskal, Smruti Rashmi, Ann E Jerse, Ana Cehovin, Jeremy P Derrick, Christoph M Tang

Source: PLoS Pathogens, Vol 20, Iss 11, p e1012688 (2024)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/0b6272bd1e784526b32874625ff2ee64

Evolution, persistence, and host adaption of a gonococcal AMR plasmid that emerged in the pre-antibiotic era.

Authors: Wearn-Xin Yee, Muhammad Yasir, A Keith Turner, David J Baker, Ana Cehovin, Christoph M Tang

Source: PLoS Genetics, Vol 19, Iss 5, p e1010743 (2023)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/40f3ec4adcdd4292ab94a0c56d1e67ac

Genome-wide association studies reveal the role of polymorphisms affecting factor H binding protein expression in host invasion by Neisseria meningitidis.

Authors: Sarah G Earle, Mariya Lobanovska, Hayley Lavender, Changyan Tang, Rachel M Exley, Elisa Ramos-Sevillano, Douglas F Browning, Vasiliki Kostiou, Odile B Harrison, Holly B Bratcher, Gabriele Varani, Christoph M Tang, Daniel J Wilson, Martin C J Maiden

Source: PLoS Pathogens, Vol 17, Iss 10, p e1009992 (2021)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/0b6f3dfc4de74b43a1339c59c7591f44

Type VI secretion system killing by commensal Neisseria is influenced by expression of type four pili

Authors: Rafael Custodio, Rhian M Ford, Cara J Ellison, Guangyu Liu, Gerda Mickute, Christoph M Tang, Rachel M Exley

Source: eLife, Vol 10 (2021)

Subject Terms: Neisseria cinerea, Neisseria meningitidis, T6SS, Type IV pili, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/63755; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/166cfad48bbd41369d9889d0d64efae5

Commensal Neisseria cinerea impairs Neisseria meningitidis microcolony development and reduces pathogen colonisation of epithelial cells.

Authors: Rafael Custodio, Errin Johnson, Guangyu Liu, Christoph M Tang, Rachel M Exley

Source: PLoS Pathogens, Vol 16, Iss 3, p e1008372 (2020)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/3c5f8ce28d814eac934e4a4d11f68d78

Genetic plasticity of the Shigella virulence plasmid is mediated by intra- and inter-molecular events between insertion sequences.

Authors: Giulia Pilla, Gareth McVicker, Christoph M Tang

Source: PLoS Genetics, Vol 13, Iss 9, p e1007014 (2017)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC5629016?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/c4a9d84a85da492db516ee445001d33b

Thermoregulation of Meningococcal fHbp, an Important Virulence Factor and Vaccine Antigen, Is Mediated by Anti-ribosomal Binding Site Sequences in the Open Reading Frame.

Authors: Edmund Loh, Hayley Lavender, Felicia Tan, Alexander Tracy, Christoph M Tang

Source: PLoS Pathogens, Vol 12, Iss 8, p e1005794 (2016)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/ec87130d39d04d7eb29600388e0e649c

Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility

Authors: Joseph JE Caesar, Hayley Lavender, Philip N Ward, Rachel M Exley, Jack Eaton, Emily Chittock, Talat H Malik, Elena Goiecoechea De Jorge, Matthew C Pickering, Christoph M Tang, Susan M Lea

Source: eLife, Vol 3 (2014)

Subject Terms: Neisseria meningitidis, complement evasion, genetic susceptibility, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/04008; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/70bd75d9cb164b2881f476352ff38940

Distinct binding and immunogenic properties of the gonococcal homologue of meningococcal factor h binding protein.

Authors: Ilse Jongerius, Hayley Lavender, Lionel Tan, Nicola Ruivo, Rachel M Exley, Joseph J E Caesar, Susan M Lea, Steven Johnson, Christoph M Tang

Source: PLoS Pathogens, Vol 9, Iss 8, p e1003528 (2013)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3731240?pdf=render; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/cb5ebf2b7dc04e1d853c66d45d0ea94c

Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules.

Authors: Steven Johnson, Lionel Tan, Stijn van der Veen, Joseph Caesar, Elena Goicoechea De Jorge, Rachel J Harding, Xilian Bai, Rachel M Exley, Philip N Ward, Nicola Ruivo, Kaushali Trivedi, Elspeth Cumber, Rhian Jones, Luke Newham, David Staunton, Rafael Ufret-Vincenty, Ray Borrow, Matthew C Pickering, Susan M Lea, Christoph M Tang

Source: PLoS Pathogens, Vol 8, Iss 10, p e1002981 (2012)

Subject Terms: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1002981&type=printable; https://doaj.org/toc/1553-7366; https://doaj.org/toc/1553-7374

Access URL: https://doaj.org/article/be29726a5dda472eba006fbddaa7e68a

The influence of IS1301 in the capsule biosynthesis locus on meningococcal carriage and disease.

Authors: Elisabeth Kugelberg, Bridget Gollan, Christopher Farrance, Holly Bratcher, Jay Lucidarme, Ana Belén Ibarz-Pavón, Martin C J Maiden, Ray Borrow, Christoph M Tang

Source: PLoS ONE, Vol 5, Iss 2, p e9413 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2828469?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/1f7f5ee99f814997860ffe9701bc8f52

Complete genome sequence and comparative metabolic profiling of the prototypical enteroaggregative Escherichia coli strain 042.

Authors: Roy R Chaudhuri, Mohammed Sebaihia, Jon L Hobman, Mark A Webber, Denisse L Leyton, Martin D Goldberg, Adam F Cunningham, Anthony Scott-Tucker, Paul R Ferguson, Christopher M Thomas, Gad Frankel, Christoph M Tang, Edward G Dudley, Ian S Roberts, David A Rasko, Mark J Pallen, Julian Parkhill, James P Nataro, Nicholas R Thomson, Ian R Henderson

Source: PLoS ONE, Vol 5, Iss 1, p e8801 (2010)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2808357?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/cd9e2f44dec2419cbd0ada1a80ba75e1

Evolution and exchange of plasmids in pathogenic Neisseria

Authors: Wearn-Xin Yee, Tabea Elsener, Ana Cehovin, Martin C. J. Maiden, Christoph M. Tang

Source: mSphere, Vol 8, Iss 6 (2023)

Subject Terms: evolution, plasmid, Neisseria, conjugation, AMR, HGT, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2379-5042

Access URL: https://doaj.org/article/bcc701fab6974d8299d2c069174a4a61

Evaluation of a Live Attenuated S. sonnei Vaccine Strain in the Human Enteroid Model

Authors: Giulia Pilla, Tao Wu, Christen Grassel, Jonathan Moon, Jennifer Foulke-Abel, Christoph M. Tang, Eileen M. Barry

Source: Pathogens, Vol 10, Iss 9, p 1079 (2021)

Subject Terms: Shigella sonnei, human enteroids, Shigella vaccine, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2076-0817/10/9/1079; https://doaj.org/toc/2076-0817

Access URL: https://doaj.org/article/c79461ec0421489d93f1b7bed99aaaa9

Shared mechanisms of enhanced plasmid maintenance and antibiotic tolerance mediated by the VapBC toxin:antitoxin system

Authors: Sarah Hollingshead, Gareth McVicker, Maria R. Nielsen, YuGeng Zhang, Giulia Pilla, Rebekah A. Jones, Jonathan C. Thomas, Sarah E. H. Johansen, Rachel M. Exley, Ditlev E. Brodersen, Christoph M. Tang

Source: mBio, Vol 16, Iss 2 (2025)

Subject Terms: Shigella, plasmid stability, antibiotic tolerance, TA systems, VapBC, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/380536adc2364bd4bed4b74f9f5e0ead

Towards a better understanding of antimicrobial resistance dissemination: what can be learnt from studying model conjugative plasmids?

Authors: Zhen Shen, Christoph M. Tang, Guang-Yu Liu

Source: Military Medical Research, Vol 9, Iss 1, Pp 1-11 (2022)

Subject Terms: Horizontal gene transfer, Antimicrobial resistance, Conjugative plasmids, Type IV secretion system, Restriction-modification systems, SOS response, Medicine (General), R5-920, Military Science

File Description: electronic resource

Relation: https://doaj.org/toc/2054-9369

Access URL: https://doaj.org/article/d5134c4c31ad4284b79cb6dbaa5a1daf

Et tu, Neisseria? Conflicts of Interest Between Neisseria Species

Authors: Rene Baerentsen, Christoph M. Tang, Rachel M. Exley

Source: Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)

Subject Terms: Neisseria, pathogen, commensal, antagonism, growth inhibition, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcimb.2022.913292/full; https://doaj.org/toc/2235-2988

Access URL: https://doaj.org/article/bc051f35d43341d4acbd2c7109ef12c0

Methylation of PhoP by CheR Regulates Salmonella Virulence

Authors: Yang Su, Jianhui Li, Wenting Zhang, Jinjing Ni, Rui Huang, Zuoqiang Wang, Sen Cheng, Yue Wang, Zhixin Tian, Qiuxiang Zhou, Donghai Lin, Wenjuan Wu, Christoph M. Tang, Xiaoyun Liu, Jie Lu, Yu-Feng Yao

Source: mBio, Vol 12, Iss 5 (2021)

Subject Terms: Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2150-7511

Access URL: https://doaj.org/article/19f014700315414cbc5144d4ac08ed96

DNA ADP-Ribosylation Stalls Replication and Is Reversed by RecF-Mediated Homologous Recombination and Nucleotide Excision Repair

Authors: Emeline Lawarée, Gytis Jankevicius, Charles Cooper, Ivan Ahel, Stephan Uphoff, Christoph M. Tang

Source: Cell Reports, Vol 30, Iss 5, Pp 1373-1384.e4 (2020)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124720300231; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/3e3003a16285442cb7ec8d952a71ba36