SRSF2 safeguards efficient transcription of DNA damage and repair genes

Authors: Rebecca E. Wagner, Leonie Arnetzl, Thiago Britto-Borges, Anke Heit-Mondrzyk, Ali Bakr, Etienne Sollier, Nikoletta A. Gkatza, Jasper Panten, Sylvain Delaunay, Daniela Sohn, Peter Schmezer, Duncan T. Odom, Karin Müller-Decker, Christoph Plass, Christoph Dieterich, Pavlo Lutsik, Susanne Bornelöv, Michaela Frye

Source: Cell Reports, Vol 43, Iss 11, Pp 114869- (2024)

Subject Terms: CP: Molecular biology, CP: Cancer, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124724012208; https://doaj.org/toc/2211-1247

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Detecting m6A at single-molecular resolution via direct RNA sequencing and realistic training data

Authors: Adrian Chan, Isabel S. Naarmann-de Vries, Carolin P. M. Scheitl, Claudia Höbartner, Christoph Dieterich

Source: Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/325916d9dda74ff1b556e39e8d914fa0

Machine learning for catalysing the integration of noncoding RNA in research and clinical practice

Authors: David de Gonzalo-Calvo, Kanita Karaduzovic-Hadziabdic, Louise Torp Dalgaard, Christoph Dieterich, Manel Perez-Pons, Artemis Hatzigeorgiou, Yvan Devaux, Georgios Kararigas

Source: EBioMedicine, Vol 106, Iss , Pp 105247- (2024)

Subject Terms: Artificial intelligence, Biomarker, Machine learning, Molecular pathways, Noncoding RNA, Personalised medicine, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396424002834; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/a53c6bf98be244729a4a3b6ccbd5bb8e

Comprehensive identification of diverse ribosomal RNA modifications by targeted nanopore direct RNA sequencing and JACUSA2

Authors: Isabel S. Naarmann-de Vries, Christiane Zorbas, Amina Lemsara, Michael Piechotta, Felix G. M. Ernst, Ludivine Wacheul, Denis L. J. Lafontaine, Christoph Dieterich

Source: RNA Biology, Vol 20, Iss 1, Pp 652-665 (2023)

Subject Terms: rna modification, nanopore, direct rna-seq, ribosomal rna, rna methylation, cytidine acetylation, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1547-6286; https://doaj.org/toc/1555-8584

Access URL: https://doaj.org/article/8f77b1764996404daaed691a7f7b7d25

MePMe-seq: antibody-free simultaneous m6A and m5C mapping in mRNA by metabolic propargyl labeling and sequencing

Authors: Katja Hartstock, Nadine A. Kueck, Petr Spacek, Anna Ovcharenko, Sabine Hüwel, Nicolas V. Cornelissen, Amarnath Bollu, Christoph Dieterich, Andrea Rentmeister

Source: Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/04c30eaeffb0400aa0663808a5c63a0c

Striated muscle-specific base editing enables correction of mutations causing dilated cardiomyopathy

Authors: Markus Grosch, Laura Schraft, Adrian Chan, Leonie Küchenhoff, Kleopatra Rapti, Anne-Maud Ferreira, Julia Kornienko, Shengdi Li, Michael H. Radke, Chiara Krämer, Sandra Clauder-Münster, Emerald Perlas, Johannes Backs, Michael Gotthardt, Christoph Dieterich, Maarten M. G. van den Hoogenhof, Dirk Grimm, Lars M. Steinmetz

Source: Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/287d1894c5f548b689b58cdf403063c5

A distributable German clinical corpus containing cardiovascular clinical routine doctor’s letters

Authors: Phillip Richter-Pechanski, Philipp Wiesenbach, Dominic M. Schwab, Christina Kiriakou, Mingyang He, Michael M. Allers, Anna S. Tiefenbacher, Nicola Kunz, Anna Martynova, Noemie Spiller, Julian Mierisch, Florian Borchert, Charlotte Schwind, Norbert Frey, Christoph Dieterich, Nicolas A. Geis

Source: Scientific Data, Vol 10, Iss 1, Pp 1-16 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2052-4463

Access URL: https://doaj.org/article/c652c05182474afc9633251ef8d628ec

CAG repeat expansion in the Huntington's disease gene shapes linear and circular RNAs biogenesis.

Authors: Dilara Ayyildiz, Guendalina Bergonzoni, Alan Monziani, Takshashila Tripathi, Jessica Döring, Emanuela Kerschbamer, Francesca Di Leva, Elia Pennati, Luisa Donini, Marina Kovalenko, Jacopo Zasso, Luciano Conti, Vanessa C Wheeler, Christoph Dieterich, Silvano Piazza, Erik Dassi, Marta Biagioli

Source: PLoS Genetics, Vol 19, Iss 10, p e1010988 (2023)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1010988&type=printable; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/87731a943eda4263b60cff414dc33cfe

Magnetique: an interactive web application to explore transcriptome signatures of heart failure

Authors: Thiago Britto-Borges, Annekathrin Ludt, Etienne Boileau, Enio Gjerga, Federico Marini, Christoph Dieterich

Source: Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-9 (2022)

Subject Terms: Interactive dashboard, Heart failure, Cardiomyopathies, Differential gene expression, Differential transcript usage, Protein network inference, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/6252e690fb734237942009ec7b7b7381

Evidence for correlations between BMI-associated SNPs and circRNAs

Authors: Luisa Sophie Rajcsanyi, Inga Diebels, Lydia Pastoors, Deniz Kanber, Triinu Peters, Anna-Lena Volckmar, Yiran Zheng, Martin Grosse, Christoph Dieterich, Johannes Hebebrand, Frank J. Kaiser, Bernhard Horsthemke, Anke Hinney

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/1cd7ead5088847afa8cbf877939db6c3

RNA modification mapping with JACUSA2

Authors: Michael Piechotta, Isabel S. Naarmann-de Vries, Qi Wang, Janine Altmüller, Christoph Dieterich

Source: Genome Biology, Vol 23, Iss 1, Pp 1-11 (2022)

Subject Terms: m6A, Pseudouridine, Reverse transcription signature, Nanopore, Biology (General), QH301-705.5, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1474-760X

Access URL: https://doaj.org/article/d20a1216bbce44449cbfe5394d70b3d4

Circular RNA circCCNT2 is upregulated in the anterior cingulate cortex of individuals with bipolar disorder

Authors: Rixing Lin, Juan Pablo Lopez, Cristiana Cruceanu, Caroline Pierotti, Laura M. Fiori, Alessio Squassina, Caterina Chillotti, Christoph Dieterich, Nikolaos Mellios, Gustavo Turecki

Source: Translational Psychiatry, Vol 11, Iss 1, Pp 1-8 (2021)

Subject Terms: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://doaj.org/toc/2158-3188

Access URL: https://doaj.org/article/e1375c7f13de497ab883d11db3beb395

RN7SK small nuclear RNA controls bidirectional transcription of highly expressed gene pairs in skin

Authors: Roberto Bandiera, Rebecca E. Wagner, Thiago Britto-Borges, Christoph Dieterich, Sabine Dietmann, Susanne Bornelöv, Michaela Frye

Source: Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/934626f2ca0a4f63a03c33541d00ceca

SMG5-SMG7 authorize nonsense-mediated mRNA decay by enabling SMG6 endonucleolytic activity

Authors: Volker Boehm, Sabrina Kueckelmann, Jennifer V. Gerbracht, Sebastian Kallabis, Thiago Britto-Borges, Janine Altmüller, Marcus Krüger, Christoph Dieterich, Niels H. Gehring

Source: Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/9c2915beac40413f8c56308a467df541

Full-Length Spatial Transcriptomics Reveals the Unexplored Isoform Diversity of the Myocardium Post-MI

Authors: Etienne Boileau, Xue Li, Isabel S Naarmann-de Vries, Christian Becker, Ramona Casper, Janine Altmüller, Florian Leuschner, Christoph Dieterich

Source: Frontiers in Genetics, Vol 13 (2022)

Subject Terms: spatial transcriptomics, single-cell RNA sequencing, oxford nanopore technology, myocardial infarction, visium spatial, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2022.912572/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/2b2183ae1a7843588cbdcd0db910366c

A spatially resolved brain region- and cell type-specific isoform atlas of the postnatal mouse brain

Authors: Anoushka Joglekar, Andrey Prjibelski, Ahmed Mahfouz, Paul Collier, Susan Lin, Anna Katharina Schlusche, Jordan Marrocco, Stephen R. Williams, Bettina Haase, Ashley Hayes, Jennifer G. Chew, Neil I. Weisenfeld, Man Ying Wong, Alexander N. Stein, Simon A. Hardwick, Toby Hunt, Qi Wang, Christoph Dieterich, Zachary Bent, Olivier Fedrigo, Steven A. Sloan, Davide Risso, Erich D. Jarvis, Paul Flicek, Wenjie Luo, Geoffrey S. Pitt, Adam Frankish, August B. Smit, M. Elizabeth Ross, Hagen U. Tilgner

Source: Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/b27a2afb47544e009093959c837b41e3

Targeted Analysis of circRNA Expression in Patient Samples by Lexo-circSeq

Authors: Isabel S. Naarmann-de Vries, Jessica Eschenbach, Sarah Schudy, Benjamin Meder, Christoph Dieterich

Source: Frontiers in Molecular Biosciences, Vol 9 (2022)

Subject Terms: circRNA, cardiomyopathy, SLC8A1, RBM33, RNA-seq, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2022.875805/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/fa90a8c89519419b96df97d6cfb3e016

Analysis of myocardial cellular gene expression during pressure overload reveals matrix based functional intercellular communication

Authors: Natali Froese, Julio Cordero, Aya Abouissa, Felix A. Trogisch, Steve Grein, Malgorzata Szaroszyk, Yong Wang, Anna Gigina, Mortimer Korf-Klingebiel, Berislav Bosnjak, Colin F. Davenport, Lutz Wiehlmann, Robert Geffers, Eva Riechert, Lonny Jürgensen, Etienne Boileau, Yanzhu Lin, Christoph Dieterich, Reinhold Förster, Johann Bauersachs, Roxana Ola, Gergana Dobreva, Mirko Völkers, Joerg Heineke

Source: iScience, Vol 25, Iss 3, Pp 103965- (2022)

Subject Terms: Biological sciences, Molecular biology, Systems biology, Transcriptomics, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004222002358; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/6224cc5550424983837de122401cc858

MicroRNA-138 controls hippocampal interneuron function and short-term memory in mice

Authors: Reetu Daswani, Carlotta Gilardi, Michael Soutschek, Prakruti Nanda, Kerstin Weiss, Silvia Bicker, Roberto Fiore, Christoph Dieterich, Pierre-Luc Germain, Jochen Winterer, Gerhard Schratt

Source: eLife, Vol 11 (2022)

Subject Terms: microRNA, interneuron, short-term memory, inhibitory synapse, E-I balance, schizophrenia, Medicine, Science, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://elifesciences.org/articles/74056; https://doaj.org/toc/2050-084X

Access URL: https://doaj.org/article/a5a070b8ebc54d738e70853f52978666

Automatic extraction of 12 cardiovascular concepts from German discharge letters using pre-trained language models

Authors: Phillip Richter-Pechanski, Nicolas A Geis, Christina Kiriakou, Dominic M Schwab, Christoph Dieterich

Source: Digital Health, Vol 7 (2021)

Subject Terms: Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://doaj.org/toc/2055-2076

Access URL: https://doaj.org/article/d41227b45cd844759a6de54b16972fe7