Cardiomyocyte precursors generated by direct reprogramming and molecular beacon selection attenuate ventricular remodeling after experimental myocardial infarction

Authors: Dipthi Bachamanda Somesh, Kristin Klose, Janita A. Maring, Désirée Kunkel, Karsten Jürchott, Stephanie I. Protze, Oliver Klein, Grit Nebrich, Matthias Becker, Ulrike Krüger, Timo Z. Nazari-Shafti, Volkmar Falk, Andreas Kurtz, Manfred Gossen, Christof Stamm

Source: Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-23 (2023)

Subject Terms: Cell therapy, Direct reprogramming, Fibroblast, Induced cardiomyocyte precursor, Molecular beacon, Myocardial infarction, Medicine (General), R5-920, Biochemistry, QD415-436

File Description: electronic resource

Relation: https://doaj.org/toc/1757-6512

Access URL: https://doaj.org/article/c371854fe11c4e7097810a43c278f286

Comparative analysis of adeno-associated virus serotypes for gene transfer in organotypic heart slices

Authors: Zihou Liu, Kristin Klose, Sebastian Neuber, Meng Jiang, Manfred Gossen, Christof Stamm

Source: Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)

Subject Terms: Myocardial slice, Organotypic heart slice culture, Adeno-associated virus, Gene transfer, Gene therapy, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12967-020-02605-4; https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/6540bf99637e416f83391b6066a0cf34

Deep-learning-based real-time prediction of acute kidney injury outperforms human predictive performance

Authors: Nina Rank, Boris Pfahringer, Jörg Kempfert, Christof Stamm, Titus Kühne, Felix Schoenrath, Volkmar Falk, Carsten Eickhoff, Alexander Meyer

Source: npj Digital Medicine, Vol 3, Iss 1, Pp 1-12 (2020)

Subject Terms: Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://doaj.org/toc/2398-6352

Access URL: https://doaj.org/article/f075b261cadc4b909376e8bceccb2f25

Impact of procedural variability and study design quality on the efficacy of cell-based therapies for heart failure - a meta-analysis.

Authors: Zhiyi Xu, Sebastian Neuber, Timo Nazari-Shafti, Zihou Liu, Fengquan Dong, Christof Stamm

Source: PLoS ONE, Vol 17, Iss 1, p e0261462 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261462&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/34d9a193d380414b9e8f7eb116ec0d71

Hematopoietic stem-cell senescence and myocardial repair - Coronary artery disease genotype/phenotype analysis of post-MI myocardial regeneration response induced by CABG/CD133+ bone marrow hematopoietic stem cell treatment in RCT PERFECT Phase 3

Authors: Markus Wolfien, Denise Klatt, Amankeldi A. Salybekov, Masaaki Ii, Miki Komatsu-Horii, Ralf Gaebel, Julia Philippou-Massier, Eric Schrinner, Hiroshi Akimaru, Erika Akimaru, Robert David, Jens Garbade, Jan Gummert, Axel Haverich, Holger Hennig, Hiroto Iwasaki, Alexander Kaminski, Atsuhiko Kawamoto, Christian Klopsch, Johannes T. Kowallick, Stefan Krebs, Julia Nesteruk, Hermann Reichenspurner, Christian Ritter, Christof Stamm, Ayumi Tani-Yokoyama, Helmut Blum, Olaf Wolkenhauer, Axel Schambach, Takayuki Asahara, Gustav Steinhoff

Source: EBioMedicine, Vol 57, Iss , Pp 102862- (2020)

Subject Terms: Clonal hematopoiesis of indeterminate pathology, CHIP, SH2B3, Myocardial regeneration, Cardiac stem cell therapy, Angiogenesis induction, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396420302371; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/dd58128840ab4b1fb0fa839501efef79

Cardiac Function Improvement and Bone Marrow Response –

Authors: Gustav Steinhoff, Julia Nesteruk, Markus Wolfien, Günther Kundt, Jochen Börgermann, Robert David, Jens Garbade, Jana Große, Axel Haverich, Holger Hennig, Alexander Kaminski, Joachim Lotz, Friedrich-Wilhelm Mohr, Paula Müller, Robert Oostendorp, Ulrike Ruch, Samir Sarikouch, Anna Skorska, Christof Stamm, Gudrun Tiedemann, Florian Mathias Wagner, Olaf Wolkenhauer

Source: EBioMedicine, Vol 22, Iss C, Pp 208-224 (2017)

Subject Terms: Randomised double-blinded phase III multicentre trial, CD133+, CD34+, Endothelial progenitor cell (EPC), SH2B3, Lnk adaptor, Cardiac repair, Cardiac stem cell therapy, Angiogenesis, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352396417302967; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/506c8e7e8ae54a5c92e1b4df2aea82a0

Adult Tissue Extracellular Matrix Determines Tissue Specification of Human iPSC‐Derived Embryonic Stage Mesodermal Precursor Cells

Authors: Imran Ullah, Jonas Felix Busch, Anja Rabien, Bettina Ergün, Christof Stamm, Christoph Knosalla, Stefan Hippenstiel, Petra Reinke, Andreas Kurtz

Source: Advanced Science, Vol 7, Iss 5, Pp n/a-n/a (2020)

Subject Terms: cell differentiation, extracellular matrix, pluripotent stem cells, regenerative medicine, tissue engineering, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/9da7781e490d415ebb692290691717f8

Dysregulation of proangiogeneic factors in pressure-overload left-ventricular hypertrophy results in inadequate capillary growth

Authors: Mohamed Zeriouh, Anton Sabashnikov, Arne Tenbrock, Klaus Neef, Julia Merkle, Kaveh Eghbalzadeh, Carolyn Weber, Oliver J. Liakopoulos, Antje-Christin Deppe, Christof Stamm, Douglas B. Cowan, Thorsten Wahlers, Yeong-Hoon Choi

Source: Therapeutic Advances in Cardiovascular Disease, Vol 13 (2019)

Subject Terms: Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1753-9455

Access URL: https://doaj.org/article/dcbd1d4d9555429497bd4b52206e0f08

Mesenchymal Stromal Cells Cultured in Serum from Heart Failure Patients Are More Resistant to Simulated Chronic and Acute Stress

Authors: Timo Z. Nazari-Shafti, Zhiyi Xu, Andreas Matthäus Bader, Georg Henke, Kristin Klose, Volkmar Falk, Christof Stamm

Source: Stem Cells International, Vol 2018 (2018)

Subject Terms: Internal medicine, RC31-1245

File Description: electronic resource

Relation: https://doaj.org/toc/1687-966X; https://doaj.org/toc/1687-9678

Access URL: https://doaj.org/article/3f388477e5674288af7393f61aabcb4c

Cord Blood Mesenchymal Stromal Cell-Conditioned Medium Protects Endothelial Cells via STAT3 Signaling

Authors: Andreas Matthaeus Bader, Andreja Brodarac, Kristin Klose, Karen Bieback, Yeong-Hoon Choi, Kyung-Sun Kang, Andreas Kurtz, Christof Stamm

Source: Cellular Physiology and Biochemistry, Vol 34, Iss 3, Pp 646-657 (2014)

Subject Terms: Cell therapy, Endothelial cell, Ischemia, Stem cell, Cord blood, Physiology, QP1-981, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.karger.com/Article/FullText/363030; https://doaj.org/toc/1015-8987; https://doaj.org/toc/1421-9778

Access URL: https://doaj.org/article/c0e86e0e49844fc8b0ae2ddd2851a9ff

Myocardial Regeneration via Progenitor Cell-Derived Exosomes

Authors: Janita A. Maring, Christien M. Beez, Volkmar Falk, Martina Seifert, Christof Stamm

Source: Stem Cells International, Vol 2017 (2017)

Subject Terms: Internal medicine, RC31-1245

File Description: electronic resource

Relation: https://doaj.org/toc/1687-966X; https://doaj.org/toc/1687-9678

Access URL: https://doaj.org/article/e1dfe7420ccf4aa490b968af6a6a1c71

Epithelial-to-Mesenchymal Transition Enhances the Cardioprotective Capacity of Human Amniotic Epithelial Cells

Authors: Rajika Roy, Marian Kukucka, Daniel Messroghli, Désirée Kunkel, Andreja Brodarac, Kristin Klose, Sven Geißler, Peter Moritz Becher, Sung Keun Kang, Yeong-Hoon Choi, Christof Stamm M.D.

Source: Cell Transplantation, Vol 24 (2015)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/0963-6897; https://doaj.org/toc/1555-3892

Access URL: https://doaj.org/article/61fc316aa5ee4c338c3ece85e0e78dd8

Hypoxic Preconditioning Increases Survival and Pro-Angiogenic Capacity of Human Cord Blood Mesenchymal Stromal Cells In Vitro.

Authors: Andreas Matthäus Bader, Kristin Klose, Karen Bieback, Dirk Korinth, Maria Schneider, Martina Seifert, Yeong-Hoon Choi, Andreas Kurtz, Volkmar Falk, Christof Stamm

Source: PLoS ONE, Vol 10, Iss 9, p e0138477 (2015)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4575058?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f12ea68053104158b87f475927c0136b

Dynamic Support Culture of Murine Skeletal Muscle-Derived Stem Cells Improves Their Cardiogenic Potential In Vitro

Authors: Klaus Neef, Philipp Treskes, Guoxing Xu, Florian Drey, Sureshkumar Perumal Srinivasan, Tomo Saric, Erastus Nembo, Judith Semmler, Filomain Nguemo, Christof Stamm, Douglas B. Cowan, Antje-Christin Deppe, Maximilian Scherner, Thorsten Wittwer, Jürgen Hescheler, Thorsten Wahlers, Yeong-Hoon Choi

Source: Stem Cells International, Vol 2015 (2015)

Subject Terms: Internal medicine, RC31-1245

File Description: electronic resource

Relation: https://doaj.org/toc/1687-966X; https://doaj.org/toc/1687-9678

Access URL: https://doaj.org/article/88fdd522903a4e5cbbd25eb6b942b251

Noninvasive in Vivo Tracking of Mesenchymal Stem Cells and Evaluation of Cell Therapeutic Effects in a Murine Model Using a Clinical 3.0 T MRI

Authors: Florian Drey, Yeong-Hoon Choi, Klaus Neef, Birgit Ewert, Arne Tenbrock, Philipp Treskes, Henning Bovenschulte, Oliver J. Liakopoulos, Meike Brenkmann, Christof Stamm, Thorsten Wittwer, Thorsten Wahlers

Source: Cell Transplantation, Vol 22 (2013)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/0963-6897; https://doaj.org/toc/1555-3892

Access URL: https://doaj.org/article/6555f8f171dd4e5b95f0993f891e3f90

Two-Dimensional Speckle Tracking Strain Analysis for Efficacy Assessment of Myocardial Cell Therapy

Authors: Boris A. Nasseri M.D., Marian Kukucka, Michael Dandel, Christoph Knosalla, Yeong-Hoon Choi, Wolfram Ebell, Roland Hetzer, Christof Stamm

Source: Cell Transplantation, Vol 18 (2009)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/0963-6897; https://doaj.org/toc/1555-3892

Access URL: https://doaj.org/article/8b395a12166747f0b322971fc6c00736

Myocardial hypertrophy overrides the angiogenic response to hypoxia.

Authors: Yeong-Hoon Choi, Douglas B Cowan, Meena Nathan, Dimitrios Poutias, Christof Stamm, Pedro J del Nido, Francis X McGowan

Source: PLoS ONE, Vol 3, Iss 12, p e4042 (2008)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC2603310?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/654d0390cb7c4dc786d8df085944139b

Intramyocardial Delivery of Bone Marrow Mononuclear Cells and Mechanical Assist Device Implantation in Patients with End-Stage Cardiomyopathy

Authors: Boris A. Nasseri, Marian Kukucka, Michael Dandel, Christoph Knosalla, Evgenij Potapov, Hans B. Lehmkuhl, Rudolph Meyer, Wolfram Ebell, Christof Stamm, Roland Hetzer

Source: Cell Transplantation, Vol 16 (2007)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/0963-6897; https://doaj.org/toc/1555-3892

Access URL: https://doaj.org/article/03d40b04a1404336906c668f63825b6d

Stem Cell Therapy for Ischemic Heart Disease: Beginning or End of the Road?

Authors: Christof Stamm DR, Andreas Liebold, Gustav Steinhoff, Dirk Strunk

Source: Cell Transplantation, Vol 15 (2006)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/0963-6897; https://doaj.org/toc/1555-3892

Access URL: https://doaj.org/article/37b0e15f55204948abd5d24b19b57a33

Processing of Human Cardiac Tissue Toward Extracellular Matrix Self-assembling Hydrogel for In Vitro and In Vivo Applications

Authors: Matthias Becker, author^{1, 2}, Janita A. Maring, author^{1, 2}, Barbara Oberwallner, author², Benjamin Kappler, author², Oliver Klein, author^{1, 2}, Volkmar Falk, author^{2, 3, 4, 5}, Christof Stamm, author^{2, 3, 4}

Source: Journal of Visualized Experiments. (130)

Availability: http://www.jove.com/video/56419