Hepatic IR and IGF1R signaling govern distinct metabolic and carcinogenic processes upon PTEN deficiency in the liver

Authors: Monika Gjorgjieva, Nicolas Calo, Cyril Sobolewski, Dorothea Portius, Jean-Luc Pitetti, Flavien Berthou, Anne-Sophie Ay, Marion Peyrou, Lucie Bourgoin, Christine Maeder, Margot Fournier, Marta Correia de Sousa, Etienne Delangre, Laurent Vinet, Xavier Montet, Christine Sempoux, Serge Nef, Michelangelo Foti

Source: JHEP Reports, Vol 7, Iss 4, Pp 101305- (2025)

Subject Terms: Hepatic metabolism, Hepatocarcinogenesis, Insulin receptor, IGF-1 receptor, Steatosis, Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589555924003094; https://doaj.org/toc/2589-5559

Access URL: https://doaj.org/article/47a94198f8ab42a1b3859fc35f55af3e

MiR-22 Deficiency Fosters Hepatocellular Carcinoma Development in Fatty Liver

Authors: Monika Gjorgjieva, Anne-Sophie Ay, Marta Correia de Sousa, Etienne Delangre, Dobrochna Dolicka, Cyril Sobolewski, Christine Maeder, Margot Fournier, Christine Sempoux, Michelangelo Foti

Source: Cells, Vol 11, Iss 18, p 2860 (2022)

Subject Terms: non-alcoholic fatty liver disease, hepatocellular carcinoma, microRNA, metabolism, miR-22, Thrombospondin-1, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/18/2860; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/e586bccd94ae4c939070d578c9dd7af0

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